JP2009510133A5 - - Google Patents

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Publication number
JP2009510133A5
JP2009510133A5 JP2008533836A JP2008533836A JP2009510133A5 JP 2009510133 A5 JP2009510133 A5 JP 2009510133A5 JP 2008533836 A JP2008533836 A JP 2008533836A JP 2008533836 A JP2008533836 A JP 2008533836A JP 2009510133 A5 JP2009510133 A5 JP 2009510133A5
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JP
Japan
Prior art keywords
composition
composition according
epitope
antigen
liposome
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JP2008533836A
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English (en)
Japanese (ja)
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JP2009510133A (ja
JP5528703B2 (ja
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Priority claimed from CA002523032A external-priority patent/CA2523032A1/en
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Publication of JP2009510133A publication Critical patent/JP2009510133A/ja
Publication of JP2009510133A5 publication Critical patent/JP2009510133A5/ja
Application granted granted Critical
Publication of JP5528703B2 publication Critical patent/JP5528703B2/ja
Expired - Fee Related legal-status Critical Current
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JP2008533836A 2005-10-07 2006-10-05 がん治療のためのビヒクルとして連続的疎水性相を含む担体におけるリポソームの使用 Expired - Fee Related JP5528703B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CA002523032A CA2523032A1 (en) 2005-10-07 2005-10-07 Vaccines for cancer therapy
CA2,523,032 2005-10-07
CA002533705A CA2533705A1 (en) 2005-10-07 2006-01-13 Use of liposomes in a water-in-oil emulsion or in a continuous hydrophobic carrier as a vehicle for cancer treatment
CA2,533,705 2006-01-13
CA2,542,212 2006-04-07
CA002542212A CA2542212A1 (en) 2005-10-07 2006-04-07 Use of liposomes in a water-in-oil emulsion or in a continuous hydrophobic carrier as a vehicle for cancer treatment
US80657306P 2006-07-05 2006-07-05
US60/806,573 2006-07-05
PCT/CA2006/001640 WO2007041832A1 (en) 2005-10-07 2006-10-05 Use of liposomes in a carrier comprising a continuous hydrophobic phase as a vehicle for cancer treatment

Publications (3)

Publication Number Publication Date
JP2009510133A JP2009510133A (ja) 2009-03-12
JP2009510133A5 true JP2009510133A5 (enExample) 2009-11-26
JP5528703B2 JP5528703B2 (ja) 2014-06-25

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ID=37942250

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008533836A Expired - Fee Related JP5528703B2 (ja) 2005-10-07 2006-10-05 がん治療のためのビヒクルとして連続的疎水性相を含む担体におけるリポソームの使用

Country Status (8)

Country Link
US (3) US20090297593A1 (enExample)
EP (1) EP1948225B1 (enExample)
JP (1) JP5528703B2 (enExample)
CN (1) CN101282742B (enExample)
AU (1) AU2006301891B2 (enExample)
CA (4) CA2523032A1 (enExample)
ES (1) ES2451599T3 (enExample)
WO (1) WO2007041832A1 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1486102A (en) * 2000-11-07 2002-05-21 Immunovaccine Technologies Inc Vaccines with enhanced immune response and methods for their preparation
US9090673B2 (en) * 2003-12-12 2015-07-28 City Of Hope Synthetic conjugate of CpG DNA and T-help/CTL peptide
CA2523032A1 (en) 2005-10-07 2007-04-07 Immunovaccine Technologies Inc. Vaccines for cancer therapy
EP2197497B1 (en) 2007-09-27 2016-06-01 ImmunoVaccine Technologies Inc. Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo
CA2700828C (en) * 2007-10-03 2017-01-24 Immunovaccine Technologies Inc. Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof
AU2009253780B2 (en) * 2008-06-05 2014-08-14 Immunovaccine Technologies Inc. Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance
WO2013040015A2 (en) * 2011-09-13 2013-03-21 Immunotope, Inc. Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
CN113876945A (zh) * 2011-10-06 2022-01-04 免疫疫苗技术有限公司 包括激活或增加tlr2活性的佐剂的脂质体组合物及其应用
KR20140100415A (ko) * 2013-02-05 2014-08-14 닛토덴코 가부시키가이샤 경피 투여용 백신 조성물
AU2013384879B2 (en) 2013-03-27 2018-12-13 Immunovaccine Technologies Inc. Method for improving the efficacy of a survivin vaccine in the treatment of cancer
WO2016001870A1 (en) * 2014-07-02 2016-01-07 David Lembo Oxysterols for use in the treatment and prevention of diseases caused by viruses
JP2016034944A (ja) * 2014-08-04 2016-03-17 日東電工株式会社 Ctlのアポトーシスを抑制するまたctlの誘導抑制を阻害するワクチン医薬組成物
CN107531736B (zh) 2015-01-06 2022-04-15 免疫疫苗科技公司 脂质a模拟物、其制备方法和用途
WO2016176761A1 (en) * 2015-05-01 2016-11-10 Immunovaccine Technologies Inc., Methods for potentiating an immune response using depot-forming and non-depot-forming vaccines
JP6989134B2 (ja) 2015-11-18 2022-01-05 イミューノヴァクシーン テクノロジーズ インコーポレイテッドImmunovaccine Technologies Inc. ポリi:cポリヌクレオチドアジュバント及び脂質系アジュバントを含むアジュバント系及び水を含まないワクチン組成物
EP3452083A4 (en) 2016-05-04 2020-01-01 ImmunoVaccine Technologies Inc. VACCINE COMPOSITIONS COMPRISING AN AMPHIPATHIC COMPOUND, NEOANTIGEN AND HYDROPHOBIC SUPPORT, AND METHODS OF USE THEREOF
CN109475628A (zh) 2016-05-18 2019-03-15 库尔生物制药有限公司 T细胞调节性多聚体多肽及其使用方法
JP7125197B2 (ja) 2016-09-27 2022-08-24 イミューノヴァクシーン テクノロジーズ インコーポレイテッド ヒト対象において抗体免疫応答を誘導するために低投与体積b細胞エピトープ組成物を使用する方法
AU2017379900B2 (en) * 2016-12-22 2024-12-05 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
WO2018129474A1 (en) 2017-01-09 2018-07-12 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
EP3596118B1 (en) 2017-03-15 2024-08-21 Cue Biopharma, Inc. Combination of multimeric fusion polypeptides and immune checkpoint inhibitor for treating hpv-associated cancer
WO2019139896A1 (en) 2018-01-09 2019-07-18 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof
AU2019239785A1 (en) * 2018-03-20 2020-10-08 Immunovaccine Technologies Inc. Methods and compositions for targeted delivery of active agents and immunomodulatory agents to lymph nodes
EP4149534A4 (en) 2020-05-12 2024-09-04 Cue Biopharma, Inc. MULTIMERIC POLYPEPTIDES MODULATING T CELLS AND METHODS OF USE THEREOF
WO2022056014A1 (en) 2020-09-09 2022-03-17 Cue Biopharma, Inc. Mhc class ii t-cell modulatory multimeric polypeptides for treating type 1 diabetes mellitus (t1d) and methods of use thereof
CN116531498A (zh) * 2023-04-11 2023-08-04 金宇保灵生物药品有限公司 一种免疫增强剂、制备方法及其应用

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090406A (en) * 1984-04-12 2000-07-18 The Liposome Company, Inc. Potentiation of immune responses with liposomal adjuvants
US5897873A (en) * 1984-04-12 1999-04-27 The Liposome Company, Inc. Affinity associated vaccine
US6093406A (en) * 1988-06-02 2000-07-25 The United States Of America As Represented By The Secretary Of The Army Vaccine for induction of immunity to malaria
FR2649013B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable
US5015476A (en) * 1989-08-11 1991-05-14 Paravax, Inc. Immunization implant and method
IE904098A1 (en) * 1989-11-13 1991-05-22 Nova Pharm Corp Lipospheres for controlled delivery of substances
US5709879A (en) * 1990-06-29 1998-01-20 Chiron Corporation Vaccine compositions containing liposomes
FI925835L (fi) 1990-06-29 1992-12-22 Chiron Corp Vacciner innehaollande liposomer
KR100252371B1 (ko) * 1990-12-12 2000-05-01 포터 더글라스 서브유니트 파필로마비루스 백신 및 그들에 사용하기 위한 펩티드
CA2072249C (en) * 1991-06-28 2003-06-17 Saiko Hosokawa Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
WO1993025231A1 (en) 1992-06-05 1993-12-23 Dalhousie University Use of zona pellucida glycoproteins for immunocontraception
USRE37224E1 (en) * 1992-06-05 2001-06-12 Dalhousie University Method to prevent fertilization in mammals by administering a single dose of zona pellucida derived antigens, liposome and adjuvant
US5736141A (en) * 1992-06-05 1998-04-07 Dalhousie University Method to prevent fertilization in mammals by administering a single dose of zona pellucida derived antigens, liposome and Freund's adjuvant
US5820879A (en) * 1993-02-12 1998-10-13 Access Pharmaceuticals, Inc. Method of delivering a lipid-coated condensed-phase microparticle composition
JPH06247842A (ja) * 1993-02-23 1994-09-06 Green Cross Corp:The リポソーム組成物の製造方法
EP0721341A4 (en) * 1993-08-06 1998-04-22 Cytel Corp CLONING AND DESCRIPTION OF FULL MAGE-1 GENE CHARACTERISTICS
US20050049197A1 (en) * 1993-09-14 2005-03-03 Epimmune Inc. Induction of immune response against desired determinants
US5874560A (en) * 1994-04-22 1999-02-23 The United States Of America As Represented By The Department Of Health And Human Services Melanoma antigens and their use in diagnostic and therapeutic methods
WO1995031480A1 (en) * 1994-05-18 1995-11-23 S.P.I. Synthetic Peptides Incorporated Heterodimer polypeptide immunogen carrier composition and method
US5637300A (en) * 1994-08-03 1997-06-10 Dunbar; Bonnie S. Contraceptive vaccine comprising a glycosylated 55 kD zona pellucida protein immunogen and method of use of the same in contraception
US6355256B1 (en) * 1994-09-30 2002-03-12 Ludwig Institute For Cancer Research Compositions containing a p53 derived protein or peptide, an adjuvant, and interleukin-12 and uses thereof
US5705151A (en) * 1995-05-18 1998-01-06 National Jewish Center For Immunology & Respiratory Medicine Gene therapy for T cell regulation
AU6330896A (en) * 1995-06-07 1996-12-30 Governors Of The University Of Alberta, The A method for eliciting a th1-specific immune response
US6096313A (en) * 1996-02-09 2000-08-01 Ludwig Institute For Cancer Research Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant
US5840839A (en) * 1996-02-09 1998-11-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein
US7019112B1 (en) * 1996-03-19 2006-03-28 University Of Virginia Patent Foundation Peptides recognized by melanoma-specific A1-, A2- and A3-restricted cytoxic lymphocytes, and uses therefor
US5919480A (en) * 1996-06-24 1999-07-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Liposomal influenza vaccine composition and method
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US5910306A (en) * 1996-11-14 1999-06-08 The United States Of America As Represented By The Secretary Of The Army Transdermal delivery system for antigen
WO1998053799A2 (en) * 1997-05-28 1998-12-03 Jenner Biotherapies, Inc. Immunogenic compositions
US6977074B2 (en) * 1997-07-10 2005-12-20 Mannkind Corporation Method of inducing a CTL response
EP1015468A4 (en) * 1997-08-29 2000-09-06 Human Genome Sciences Inc FOLLISTATINE-3
US6291430B1 (en) * 1997-09-12 2001-09-18 Ludwig Institute For Cancer Research Mage-3 peptides presented by HLA class II molecules
US6183746B1 (en) * 1997-10-09 2001-02-06 Zycos Inc. Immunogenic peptides from the HPV E7 protein
ES2284247T3 (es) * 1998-04-03 2007-11-01 University Of Iowa Research Foundation Metodos y productos para estimular el sistema inmunitario usando oligonucleotidos y citoquinas inmunoterapeuticos.
US6588671B2 (en) * 1998-04-09 2003-07-08 Dcard, Inc. Positioning of a recording head for a data storage device
US6472375B1 (en) * 1998-04-16 2002-10-29 John Wayne Cancer Institute DNA vaccine and methods for its use
US6632447B1 (en) * 1998-05-07 2003-10-14 The University Of Tennessee Research Corporation Method for chemoprevention of prostate cancer
GB9810236D0 (en) * 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US6406719B1 (en) * 1998-05-13 2002-06-18 Microbiological Research Authority Encapsulation of bioactive agents
ATE480566T1 (de) * 1998-06-15 2010-09-15 Quest Pharmatech Inc Immuntherapeutische zusammensetzung und verfahren zur behandlung von prostatakrebs
WO2000000178A1 (en) * 1998-06-30 2000-01-06 Rohto Pharmaceutical Co., Ltd. Compositions containing liposomes and/or emulsions and process for the preparation thereof
US20050084524A1 (en) * 1998-09-30 2005-04-21 Alza Corporation Method for potentiating activity of a chemotherapeutic drug
US6787154B2 (en) * 1998-10-20 2004-09-07 Salvatore Albani Artificial antigen presenting cells
CA2356452A1 (en) 1998-12-22 2000-06-29 Robert Brown Compositions and methods for reducing or preventing fertilization in fish and birds
WO2000071671A2 (en) * 1999-05-26 2000-11-30 New York University New mutant genes in familial british dementia and familial danish dementia
JP2003511420A (ja) * 1999-10-13 2003-03-25 カイロン コーポレイション タンパク質から細胞性免疫応答を得る方法
US6511676B1 (en) * 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
US7026443B1 (en) * 1999-12-10 2006-04-11 Epimmune Inc. Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions
US6602510B1 (en) * 2000-04-05 2003-08-05 Epimmune Inc. HLA class I A2 tumor associated antigen peptides and vaccine compositions
AU1486102A (en) * 2000-11-07 2002-05-21 Immunovaccine Technologies Inc Vaccines with enhanced immune response and methods for their preparation
EP1343476B1 (en) 2000-12-01 2008-05-28 Biomira Inc. Preparation of large liposomes by infusion into peg
WO2002070006A2 (en) 2000-12-08 2002-09-12 Academisch Ziekenhuis Leiden Long peptides of 22-45 amino acid residues that induce and/or enhance antigen specific immune responses
CN1168740C (zh) * 2001-04-04 2004-09-29 上海美恩生物技术有限公司 细胞因子基因修饰的抗原提呈细胞/肿瘤细胞偶联物、其制法和用途
US20050037061A1 (en) * 2001-07-25 2005-02-17 Saiko Hosokawa Remedies for mammary cancer
CA2454750C (en) * 2001-07-31 2012-09-18 David M. Koelle Immunologically significant herpes simplex virus antigens and methods for using same
US7056515B2 (en) * 2002-02-08 2006-06-06 Immunovaccine Technologies Inc. Antigens for immunocontraception
WO2003066680A2 (en) 2002-02-08 2003-08-14 Immunovaccine Technologies Inc. Antigens for immunocontraception
JP2005535627A (ja) * 2002-06-25 2005-11-24 シティ・オブ・ホープ アジュバント不含ペプチド・ワクチン
JP2004051238A (ja) 2002-07-16 2004-02-19 Canon Inc シート搬送装置及び画像形成装置
US6586671B1 (en) 2002-08-06 2003-07-01 Interrail Signal, Inc. Above ground track signal terminal apparatus
WO2004017944A1 (en) * 2002-08-23 2004-03-04 Neopharm, Inc. Liposomal gemcitabine compositions for better drug delivery
EP1393720A1 (en) * 2002-08-27 2004-03-03 Universiteit Utrecht Vesicle-encapsulated corticosteroids for treatment of cancer
US7179645B2 (en) * 2002-09-24 2007-02-20 Antigen Express, Inc. Ii-Key/antigenic epitope hybrid peptide vaccines
DE10249401A1 (de) * 2002-10-23 2004-05-13 Bernina Biosystems Gmbh Liposomen formende Zusammensetzung
US20050158375A1 (en) * 2002-11-15 2005-07-21 Toshikiro Kimura Pharmaceutical composition containing liposomes for treating cancer
AU2003296330A1 (en) * 2002-12-10 2004-06-30 Epimmune Inc. Hla-a1, a2 -a3,-a24,-b7,and -b44 tumor associated antigen peptides and compositions
PT1575977E (pt) * 2002-12-23 2009-12-15 Dynavax Tech Corp Oligonucleótidos de sequência imunoestimuladora e métodos de utilização dos mesmos
JP2007524380A (ja) * 2003-04-02 2007-08-30 ボード オブ リージェンツ ザ ユニバーティー オブ テキサス システム 抗腫瘍効果をもつBik変異型
ES2456666T3 (es) * 2003-04-18 2014-04-23 Biotech Synergy, Inc. Péptidos antígenos HLA-A2 asociados a un tumor y composiciones
EP1660636A4 (en) * 2003-08-26 2009-07-01 Univ Texas VACCINES AGAINST CANCER
US20050220781A1 (en) * 2003-09-04 2005-10-06 Duen-Hwa Yan IFIX, a novel HIN-200 protein, for cancer therapy
GB0321615D0 (en) * 2003-09-15 2003-10-15 Glaxo Group Ltd Improvements in vaccination
AU2005222776A1 (en) * 2003-12-31 2005-09-29 Genimmune N.V. Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions
JP2007522119A (ja) * 2004-01-28 2007-08-09 キュリックス エーピーエス アミロイド関連疾患用ワクチンとしてのアミロイドタンパク質のコンジュゲート
DK1737966T3 (da) * 2004-04-02 2012-07-09 Univ Texas Cancerspecifik promotorer
CA2566559C (en) * 2004-05-17 2014-05-06 Inex Pharmaceuticals Corporation Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof
CA2523032A1 (en) 2005-10-07 2007-04-07 Immunovaccine Technologies Inc. Vaccines for cancer therapy

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