ATE196297T1 - Heterodimere trägerzusammensetzung von immunogenen polypeptiden und verfahren zu deren verwendung - Google Patents

Heterodimere trägerzusammensetzung von immunogenen polypeptiden und verfahren zu deren verwendung

Info

Publication number
ATE196297T1
ATE196297T1 AT95918481T AT95918481T ATE196297T1 AT E196297 T1 ATE196297 T1 AT E196297T1 AT 95918481 T AT95918481 T AT 95918481T AT 95918481 T AT95918481 T AT 95918481T AT E196297 T1 ATE196297 T1 AT E196297T1
Authority
AT
Austria
Prior art keywords
heterodimeric
carrier composition
immunogenic polypeptides
subunit
cell antigen
Prior art date
Application number
AT95918481T
Other languages
English (en)
Inventor
Michael E Houston
Nian E Zhou
Cyril M Kay
Robert S Hodges
Paul J Cachia
Randall T Irvin
Original Assignee
Synthetic Peptides Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthetic Peptides Inc filed Critical Synthetic Peptides Inc
Application granted granted Critical
Publication of ATE196297T1 publication Critical patent/ATE196297T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT95918481T 1994-05-18 1995-05-18 Heterodimere trägerzusammensetzung von immunogenen polypeptiden und verfahren zu deren verwendung ATE196297T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24550794A 1994-05-18 1994-05-18
PCT/CA1995/000293 WO1995031480A1 (en) 1994-05-18 1995-05-18 Heterodimer polypeptide immunogen carrier composition and method

Publications (1)

Publication Number Publication Date
ATE196297T1 true ATE196297T1 (de) 2000-09-15

Family

ID=22926961

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95918481T ATE196297T1 (de) 1994-05-18 1995-05-18 Heterodimere trägerzusammensetzung von immunogenen polypeptiden und verfahren zu deren verwendung

Country Status (7)

Country Link
EP (1) EP0759941B1 (de)
JP (2) JP3872813B2 (de)
AT (1) ATE196297T1 (de)
AU (1) AU708472B2 (de)
CA (1) CA2190494C (de)
DE (1) DE69518838T2 (de)
WO (1) WO1995031480A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11512620A (ja) * 1995-10-06 1999-11-02 ペンス 発現されたタンパク質の検出および精製のためのコイルドコイルヘテロダイマー法および組成物
JP2001502658A (ja) * 1996-04-03 2001-02-27 ペプレサーチ・エー／エス 非樹状中心骨格ペプチド担体
US6130037A (en) * 1996-04-25 2000-10-10 Pence And Mcgill University Biosensor device and method
US6165335A (en) 1996-04-25 2000-12-26 Pence And Mcgill University Biosensor device and method
US6271198B1 (en) 1996-11-06 2001-08-07 Genentech, Inc. Constrained helical peptides and methods of making same
CA2329689A1 (en) 1998-06-12 1999-12-23 The Governors Of The University Of Alberta Composition and method for treatment of pseudomonas
AR020102A1 (es) * 1998-07-30 2002-04-10 Ucb Sa Compuesto para la prevencion y/o tratamiento de la alergia; composicion farmaceutica, composicion cosmetica, composicion en forma de bebida, alimento y/oalimento para animales domesticos que lo comprende y uso de dicho compuesto o dicha composicion farmaceutica para la fabricacion de un alimento
WO2000052456A1 (en) 1999-03-02 2000-09-08 Helix Biopharma Corporation Biosensor device and method
EE200100552A (et) 1999-04-23 2002-12-16 Pharmexa A/S Meetod kasvuteguri IL-5 aktiivsuse in vivo mahasurumiseks, IL-5 analoog, seda kodeeriv nukleiinhappefragment ning kasutamine immunogeense kompositsiooni valmistamiseks
US6872806B1 (en) 1999-06-25 2005-03-29 The Governors Of The University Of Alberta Polypeptide compositions formed using a coiled-coil template and methods of use
JP2004503565A (ja) * 2000-06-14 2004-02-05 サイトヴァックス・バイオテクノロジーズ・インコーポレーテッド 構造特異的ペプチドを生産するためのコイルドコイル構造的骨格の使用
CN100577203C (zh) * 2002-07-18 2010-01-06 赫利克斯生物药品公司 尿素酶用于抑制癌症细胞生长的用途
US7264800B2 (en) 2002-07-18 2007-09-04 Helix Biopharma Corporation Method and composition for inhibiting cancer cell growth
CA2543200A1 (en) * 2003-10-24 2005-05-06 National Research Council Of Canada Ligand-pseudoreceptor system for generation of adenoviral vectors with altered tropism
US8193310B2 (en) 2004-03-19 2012-06-05 The University Of Queensland Alpha helical mimics, their uses and methods for their production
CA2523032A1 (en) 2005-10-07 2007-04-07 Immunovaccine Technologies Inc. Vaccines for cancer therapy
CN106310293A (zh) 2007-09-27 2017-01-11 免疫疫苗技术有限公司 在包括连续疏水相的载体中的脂质体在体内输送多核苷酸中的应用
US20110070298A1 (en) 2008-06-05 2011-03-24 Immunovaccine Technologies Inc. Compositions Comprising Liposomes, An Antigen, A Polynucleotide and A Carrier Comprising a Continuous Phase of a Hydrophobic Substance
CN102946901A (zh) 2010-01-26 2013-02-27 科罗拉多大学董事会，法人 模板化成双链卷曲螺旋的呼吸病毒表位及其在免疫中的应用
EP2704693A4 (de) * 2011-04-29 2015-01-28 Selecta Biosciences Inc Gesteuerte freisetzung von immunsuppressiva aus synthetischen nanoträgern
BR112014007927B1 (pt) 2011-10-06 2021-04-13 Immunovaccine Technologies Inc Composições de lipossoma compreendendo um adjuvante e usos das referidas composições e usos das referidas composições
WO2013083254A1 (en) 2011-12-09 2013-06-13 Bavarian Nordic A/S Poxvirus vector for the expression of bacterial antigens linked to tetanus toxin fragment c
CN110251675A (zh) 2013-05-03 2019-09-20 西莱克塔生物科技公司 降低或预防响应于非变应原性抗原的过敏反应的致耐受性合成纳米载体
WO2016037163A1 (en) 2014-09-07 2016-03-10 Selecta Biosciences, Inc. Methods and compositions for attenuating gene therapy anti-viral transfer vector immune responses
WO2018169811A1 (en) 2017-03-11 2018-09-20 Selecta Biosciences, Inc. Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant
WO2019246508A1 (en) 2018-06-21 2019-12-26 Shattuck Labs, Inc. Heterodimeric proteins and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015110A1 (en) * 1992-01-31 1993-08-05 Whitehead Institute For Biomedical Research Amino acid sequences which pair specifically

Also Published As

Publication number Publication date
JP2006257095A (ja) 2006-09-28
JP3872813B2 (ja) 2007-01-24
WO1995031480A1 (en) 1995-11-23
DE69518838T2 (de) 2001-05-03
EP0759941A1 (de) 1997-03-05
DE69518838D1 (de) 2000-10-19
AU2441895A (en) 1995-12-05
CA2190494A1 (en) 1995-11-23
JPH10504018A (ja) 1998-04-14
CA2190494C (en) 2002-05-07
AU708472B2 (en) 1999-08-05
EP0759941B1 (de) 2000-09-13

Similar Documents

Publication Publication Date Title
ATE196297T1 (de) Heterodimere trägerzusammensetzung von immunogenen polypeptiden und verfahren zu deren verwendung
DK1273304T4 (da) Anvendelse af interleukin-15
NZ503763A (en) Antigenic compositions and vaccines comprising a high molecular weight (HMW) protein of Clamydia for therapeutic and prophylactic use
IT8947938A0 (it) Adsorbati di resina, procedimento per prepararli e composizioni farmaceutiche che li contengono
DE69120040T2 (de) Selbsthärtende keramisierbare Polysiloxane
ATE196314T1 (de) Verfahren und zusammensetzungen zur verhinderung von entzündungen und angiogenese enthaltend säugetieren cd97 alpha untereinheit
DE69232078T2 (de) Absorbierbare, chirurgische Klammer sowie ebensolcher Halter mit reduzierter Masse
DK146688D0 (da) Blegemiddelaktivatorsammensaetning, detergentsammensaetning indeholdende samme fremgangsmaade til fremstilling af saadanne sammensaetninger
EP0651818A4 (de) Immunogene peptide, antikörper sowie deren verwendungen im zusammenhang mit der cd4-rezeptorbindung.
CY1109710T1 (el) Επιτοπα βοηθητικων τ λεμφοκυτταρων
DE3850185D1 (de) Härtbare Verbindungen, deren Herstellung und Verwendung.
TR199700834T1 (xx) 1-Aril-2-Akilamino ethan bile�ikleri ve bunlar�n n�rokinin olarak �zellikle n�rokinin 1 has�mlar� olarak kullan�mlar�.
GR3029264T3 (en) Anti-feline immunodeficiency virus (fiv) vaccines.
TW272197B (de)
IL74147A0 (en) Substituted hexahydro-aryl-quinolizines and salts thereof and pharmaceutical compositions containing them
DK0783521T3 (da) Polypeptidforbindelser indeholdende D-2-alkyltryptophan, hvilke er i stand til at fremme frigivelsen af væksthormon
FR2630430B1 (fr) Nouvelles compositions vitreuses luminescentes, leur preparation et leur application
DE59003113D1 (de) Bindemittelkombinationen, ein Verfahren zu ihrer Herstellung und ihre Verwendung.
HUP0003396A1 (hu) Szomatosztatin antagonista peptidek
DE68901587D1 (de) Aus hydroxyimidazolinen und polyaminen hergestellte zusammensetzungen und deren verwendung als zusaetze fuer brennstoffe.
MY102593A (en) Antigents of plasmodium falciparum
IT8721159A0 (it) Amidi di amino tioacetali ciclici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
ES8707729A1 (es) Un procedimiento para la preparacion de hexahidroarilquinolizinas sustituidas.
DE3853710T2 (de) Siliciumatome und Imidogruppen enthaltende Oligomere, härtbare Zusammensetzungen und deren Herstellung.
IT9020295A0 (it) Procedimento di dosaggio di anti-corpi igg anti-allergeni specifici, frazione ricca in ihg4 ottenuta secondo questo procedimento e composizione farmaceutica contenente questa frazione

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties