ATE196314T1 - Verfahren und zusammensetzungen zur verhinderung von entzündungen und angiogenese enthaltend säugetieren cd97 alpha untereinheit - Google Patents
Verfahren und zusammensetzungen zur verhinderung von entzündungen und angiogenese enthaltend säugetieren cd97 alpha untereinheitInfo
- Publication number
- ATE196314T1 ATE196314T1 AT97946405T AT97946405T ATE196314T1 AT E196314 T1 ATE196314 T1 AT E196314T1 AT 97946405 T AT97946405 T AT 97946405T AT 97946405 T AT97946405 T AT 97946405T AT E196314 T1 ATE196314 T1 AT E196314T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- methods
- angiogenesis
- alpha subunit
- preventing inflammation
- Prior art date
Links
- 102100026423 Adhesion G protein-coupled receptor E5 Human genes 0.000 title abstract 5
- 101000718243 Homo sapiens Adhesion G protein-coupled receptor E5 Proteins 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 title 1
- 241000124008 Mammalia Species 0.000 title 1
- 230000033115 angiogenesis Effects 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2787196P | 1996-10-25 | 1996-10-25 | |
| PCT/US1997/019772 WO1998017796A2 (en) | 1996-10-25 | 1997-10-24 | Methods and compositions for inhibiting inflammation and angiogenesis comprising a mammalian cd97 alpha subunit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE196314T1 true ATE196314T1 (de) | 2000-09-15 |
Family
ID=21840250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97946405T ATE196314T1 (de) | 1996-10-25 | 1997-10-24 | Verfahren und zusammensetzungen zur verhinderung von entzündungen und angiogenese enthaltend säugetieren cd97 alpha untereinheit |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6365712B1 (de) |
| EP (1) | EP0938557B1 (de) |
| JP (1) | JP2001510987A (de) |
| AT (1) | ATE196314T1 (de) |
| AU (1) | AU5158098A (de) |
| CA (1) | CA2270154A1 (de) |
| DE (1) | DE69703121D1 (de) |
| WO (1) | WO1998017796A2 (de) |
Families Citing this family (63)
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|---|---|---|---|---|
| AU768859B2 (en) * | 1999-07-29 | 2004-01-08 | Dyax Corp. | Binding moieties for fibrin |
| US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
| US9364565B2 (en) * | 2000-03-15 | 2016-06-14 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods of using same |
| CA2400319C (en) | 2000-03-15 | 2008-09-16 | Orbus Medical Technologies Inc. | Coating that promotes endothelial cell adherence |
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| US8088060B2 (en) | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
| US20030229393A1 (en) * | 2001-03-15 | 2003-12-11 | Kutryk Michael J. B. | Medical device with coating that promotes cell adherence and differentiation |
| US20070141107A1 (en) * | 2000-03-15 | 2007-06-21 | Orbusneich Medical, Inc. | Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device |
| US20070055367A1 (en) * | 2000-03-15 | 2007-03-08 | Orbus Medical Technologies, Inc. | Medical device with coating that promotes endothelial cell adherence and differentiation |
| GB0009181D0 (en) * | 2000-04-13 | 2000-05-31 | Isis Innovation | Protein |
| GB2367822A (en) * | 2000-06-19 | 2002-04-17 | Smithkline Beecham Corp | CD97 polypeptides |
| US6984373B2 (en) | 2000-12-23 | 2006-01-10 | Dyax Corp. | Fibrin binding moieties useful as imaging agents |
| WO2002064093A2 (en) | 2001-02-15 | 2002-08-22 | King Pharmaceuticals, Inc. | Stabilized pharmaceutical and thyroid hormone compositions and method of preparation |
| US8722654B2 (en) | 2001-03-02 | 2014-05-13 | The Brigham And Women's Hospital, Inc. | Lipoxin analogs as novel inhibitors of angiogenesis |
| EP1406698B1 (de) | 2001-03-02 | 2008-10-29 | The Brigham and Women's Hospital | Lipoxin analoge als neue inhibitoren der angiogenese |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| WO2003062438A1 (en) * | 2002-01-22 | 2003-07-31 | Biomatera Inc. | Method of drying biodegradable polymers |
| US7727718B2 (en) * | 2005-01-04 | 2010-06-01 | Molecular Research Center, Inc. | Reagents for storage and preparation of samples for DNA analysis |
| EP1981338A2 (de) * | 2006-01-13 | 2008-10-22 | Advanced Bionutrition Corporation | Produktionssystem mit kontinuierlicher sprühnebelaufnahme |
| US8968210B2 (en) | 2008-10-01 | 2015-03-03 | Covidien LLP | Device for needle biopsy with integrated needle protection |
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| WO2011102394A1 (ja) | 2010-02-17 | 2011-08-25 | 日本たばこ産業株式会社 | 植物内容成分の調節因子、およびその利用 |
| EA030220B1 (ru) | 2013-06-28 | 2018-07-31 | Эмджен Инк. | Устойчивая жидкая композиция, содержащая amg-416 (этелкалцетид) |
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| JP2017528433A (ja) | 2014-07-21 | 2017-09-28 | ノバルティス アーゲー | 低い免疫増強用量のmTOR阻害剤とCARの組み合わせ |
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| US12128069B2 (en) | 2015-04-23 | 2024-10-29 | The Trustees Of The University Of Pennsylvania | Treatment of cancer using chimeric antigen receptor and protein kinase a blocker |
| EP3331913A1 (de) | 2015-08-07 | 2018-06-13 | Novartis AG | Behandlung von krebs mithilfe von chimären cd3-rezeptor-proteinen |
| PL3380620T3 (pl) | 2015-11-23 | 2024-11-12 | Novartis Ag | Zoptymalizowane lentiwirusowe wektory transferowe i ich zastosowanie |
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| KR20190036551A (ko) | 2016-08-01 | 2019-04-04 | 노파르티스 아게 | Pro-m2 대식세포 분자의 억제제를 병용하는, 키메라 항원 수용체를 이용한 암의 치료 |
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| CN111566124A (zh) | 2017-10-25 | 2020-08-21 | 诺华股份有限公司 | 制备表达嵌合抗原受体的细胞的方法 |
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| US20210213063A1 (en) | 2018-05-25 | 2021-07-15 | Novartis Ag | Combination therapy with chimeric antigen receptor (car) therapies |
| WO2019237035A1 (en) | 2018-06-08 | 2019-12-12 | Intellia Therapeutics, Inc. | Compositions and methods for immunooncology |
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| KR20210106437A (ko) | 2018-12-20 | 2021-08-30 | 노파르티스 아게 | 3-(1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체를 포함하는 투약 요법 및 약학적 조합물 |
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| WO2020219742A1 (en) | 2019-04-24 | 2020-10-29 | Novartis Ag | Compositions and methods for selective protein degradation |
| CN110627903B (zh) * | 2019-10-29 | 2021-09-21 | 河南大学 | 抗cd97单克隆抗体、其可变区与恒定区序列及应用 |
| JP2023506958A (ja) | 2019-12-20 | 2023-02-20 | ノバルティス アーゲー | 骨髄線維症および骨髄異形成症候群を処置するための、デシタビンまたは抗pd-1抗体スパルタリズマブを伴うかまたは伴わない抗tim-3抗体mbg453および抗tgf-ベータ抗体nis793の組合せ |
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| TW202304979A (zh) | 2021-04-07 | 2023-02-01 | 瑞士商諾華公司 | 抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途 |
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| WO2023214325A1 (en) | 2022-05-05 | 2023-11-09 | Novartis Ag | Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors |
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| AU2024276994A1 (en) | 2023-05-24 | 2025-10-23 | Kumquat Biosciences Inc. | Heterocyclic compounds and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2263219A1 (en) | 1996-08-09 | 1998-02-19 | Stichting Sanquin Bloedvoorziening | Methods and means for modifying complement activation |
-
1997
- 1997-10-24 EP EP97946405A patent/EP0938557B1/de not_active Expired - Lifetime
- 1997-10-24 US US09/284,819 patent/US6365712B1/en not_active Expired - Fee Related
- 1997-10-24 JP JP51974798A patent/JP2001510987A/ja active Pending
- 1997-10-24 WO PCT/US1997/019772 patent/WO1998017796A2/en not_active Ceased
- 1997-10-24 AT AT97946405T patent/ATE196314T1/de not_active IP Right Cessation
- 1997-10-24 CA CA002270154A patent/CA2270154A1/en not_active Abandoned
- 1997-10-24 AU AU51580/98A patent/AU5158098A/en not_active Abandoned
- 1997-10-24 DE DE69703121T patent/DE69703121D1/de not_active Expired - Lifetime
-
2002
- 2002-01-29 US US10/059,506 patent/US6846911B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001510987A (ja) | 2001-08-07 |
| EP0938557A2 (de) | 1999-09-01 |
| CA2270154A1 (en) | 1998-04-30 |
| AU5158098A (en) | 1998-05-15 |
| DE69703121D1 (de) | 2000-10-19 |
| US6365712B1 (en) | 2002-04-02 |
| EP0938557B1 (de) | 2000-09-13 |
| WO1998017796A2 (en) | 1998-04-30 |
| WO1998017796A3 (en) | 1998-07-09 |
| US20020168361A1 (en) | 2002-11-14 |
| US6846911B2 (en) | 2005-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |