DE69518838D1 - Heterodimere trägerzusammensetzung von immunogenen polypeptiden und verfahren zu deren verwendung - Google Patents

Heterodimere trägerzusammensetzung von immunogenen polypeptiden und verfahren zu deren verwendung

Info

Publication number
DE69518838D1
DE69518838D1 DE69518838T DE69518838T DE69518838D1 DE 69518838 D1 DE69518838 D1 DE 69518838D1 DE 69518838 T DE69518838 T DE 69518838T DE 69518838 T DE69518838 T DE 69518838T DE 69518838 D1 DE69518838 D1 DE 69518838D1
Authority
DE
Germany
Prior art keywords
heterodime
composition
immunogenic polypeptides
subunit
cell antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69518838T
Other languages
English (en)
Other versions
DE69518838T2 (de
Inventor
E Houston
E Zhou
M Kay
S Hodges
J Cachia
T Irvin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Protein Engineering Network Of Centres Of Exce
Original Assignee
SPI Synthetic Peptides Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SPI Synthetic Peptides Inc filed Critical SPI Synthetic Peptides Inc
Publication of DE69518838D1 publication Critical patent/DE69518838D1/de
Application granted granted Critical
Publication of DE69518838T2 publication Critical patent/DE69518838T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69518838T 1994-05-18 1995-05-18 Heterodimere trägerzusammensetzung von immunogenen polypeptiden und verfahren zu deren verwendung Expired - Fee Related DE69518838T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24550794A 1994-05-18 1994-05-18
PCT/CA1995/000293 WO1995031480A1 (en) 1994-05-18 1995-05-18 Heterodimer polypeptide immunogen carrier composition and method

Publications (2)

Publication Number Publication Date
DE69518838D1 true DE69518838D1 (de) 2000-10-19
DE69518838T2 DE69518838T2 (de) 2001-05-03

Family

ID=22926961

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69518838T Expired - Fee Related DE69518838T2 (de) 1994-05-18 1995-05-18 Heterodimere trägerzusammensetzung von immunogenen polypeptiden und verfahren zu deren verwendung

Country Status (7)

Country Link
EP (1) EP0759941B1 (de)
JP (2) JP3872813B2 (de)
AT (1) ATE196297T1 (de)
AU (1) AU708472B2 (de)
CA (1) CA2190494C (de)
DE (1) DE69518838T2 (de)
WO (1) WO1995031480A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997012988A1 (en) * 1995-10-06 1997-04-10 Pence Coiled-coil heterodimer methods and compositions for the detection and purification of expressed proteins
CN1215404A (zh) * 1996-04-03 1999-04-28 佩普里瑟奇公司 非树状骨架肽载体
US6130037A (en) * 1996-04-25 2000-10-10 Pence And Mcgill University Biosensor device and method
US6165335A (en) 1996-04-25 2000-12-26 Pence And Mcgill University Biosensor device and method
US6271198B1 (en) 1996-11-06 2001-08-07 Genentech, Inc. Constrained helical peptides and methods of making same
DE69906729T2 (de) 1998-06-12 2004-02-05 The Governors Of The University Of Alberta, Edmonton Zusammensetzung und methode zur behandlung von pseudomonas aeruginosa infektionen
AR020102A1 (es) * 1998-07-30 2002-04-10 Ucb Sa Compuesto para la prevencion y/o tratamiento de la alergia; composicion farmaceutica, composicion cosmetica, composicion en forma de bebida, alimento y/oalimento para animales domesticos que lo comprende y uso de dicho compuesto o dicha composicion farmaceutica para la fabricacion de un alimento
WO2000052456A1 (en) 1999-03-02 2000-09-08 Helix Biopharma Corporation Biosensor device and method
EE200100552A (et) 1999-04-23 2002-12-16 Pharmexa A/S Meetod kasvuteguri IL-5 aktiivsuse in vivo mahasurumiseks, IL-5 analoog, seda kodeeriv nukleiinhappefragment ning kasutamine immunogeense kompositsiooni valmistamiseks
US6872806B1 (en) 1999-06-25 2005-03-29 The Governors Of The University Of Alberta Polypeptide compositions formed using a coiled-coil template and methods of use
AU2001269833A1 (en) * 2000-06-14 2001-12-24 Cytovax Biotechnologies, Inc. Use of coiled-coil structural scaffold to generate structure-specific peptides
SI1530482T1 (sl) * 2002-07-18 2014-03-31 Helix Biopharma Corp. Uporaba ureaze za inhibiranje rasti rakavih celic
US7264800B2 (en) 2002-07-18 2007-09-04 Helix Biopharma Corporation Method and composition for inhibiting cancer cell growth
WO2005040333A2 (en) * 2003-10-24 2005-05-06 National Research Council Of Canada Ligand-pseudoreceptor system for generation of adenoviral vectors with altered tropism
WO2005090388A1 (en) 2004-03-19 2005-09-29 The University Of Queensland Alpha helical mimics, their uses and methods for their production
CA2523032A1 (en) 2005-10-07 2007-04-07 Immunovaccine Technologies Inc. Vaccines for cancer therapy
JP5731198B2 (ja) 2007-09-27 2015-06-10 イムノバクシーン・テクノロジーズ・インコーポレイテッドＩｍｍｕｎｏｖａｃｃｉｎｅ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． インビボでのポリヌクレオチドの送達のための連続疎水相を含む担体におけるリポソームの使用
JP5715051B2 (ja) 2008-06-05 2015-05-07 イムノバクシーン・テクノロジーズ・インコーポレイテッドＩｍｍｕｎｏｖａｃｃｉｎｅ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． リポソーム、抗原、ポリヌクレオチド及び疎水性物質の連続相を含む担体を含む組成物
CN102939101A (zh) 2010-01-26 2013-02-20 科罗拉多大学董事会，法人 用于通用疫苗的流感病毒组合物和方法
KR102112002B1 (ko) 2011-04-29 2020-05-18 셀렉타 바이오사이언시즈, 인크. 치료적 단백질에 대해 면역 반응을 감소시키는 관용원성 합성 나노운반체
US10105435B2 (en) 2011-10-06 2018-10-23 Immunovaccine Technologies Inc. Liposome compositions comprising an adjuvant that activates or increases the activity of TLR2 and uses thereof
WO2013083254A1 (en) 2011-12-09 2013-06-13 Bavarian Nordic A/S Poxvirus vector for the expression of bacterial antigens linked to tetanus toxin fragment c
CN105339012A (zh) 2013-05-03 2016-02-17 西莱克塔生物科技公司 降低i型和iv型超敏反应的致耐受性合成纳米载体的局部伴随施用
CA2957800A1 (en) 2014-09-07 2016-03-10 Selecta Biosciences, Inc. Methods and compositions for attenuating anti-viral transfer vector immune responses
WO2018169811A1 (en) 2017-03-11 2018-09-20 Selecta Biosciences, Inc. Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant
JP7439372B2 (ja) * 2018-06-21 2024-02-28 シャタック ラボ，インコーポレイテッド ヘテロ二量体タンパク質及びその使用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015110A1 (en) * 1992-01-31 1993-08-05 Whitehead Institute For Biomedical Research Amino acid sequences which pair specifically

Also Published As

Publication number Publication date
AU2441895A (en) 1995-12-05
JPH10504018A (ja) 1998-04-14
DE69518838T2 (de) 2001-05-03
CA2190494A1 (en) 1995-11-23
JP3872813B2 (ja) 2007-01-24
AU708472B2 (en) 1999-08-05
EP0759941B1 (de) 2000-09-13
ATE196297T1 (de) 2000-09-15
JP2006257095A (ja) 2006-09-28
EP0759941A1 (de) 1997-03-05
WO1995031480A1 (en) 1995-11-23
CA2190494C (en) 2002-05-07

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8327 Change in the person/name/address of the patent owner

Owner name: THE PROTEIN ENGINEERING NETWORK OF CENTRES OF EXCE

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee