JP2013121977A5 - - Google Patents
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- Publication number
- JP2013121977A5 JP2013121977A5 JP2013018233A JP2013018233A JP2013121977A5 JP 2013121977 A5 JP2013121977 A5 JP 2013121977A5 JP 2013018233 A JP2013018233 A JP 2013018233A JP 2013018233 A JP2013018233 A JP 2013018233A JP 2013121977 A5 JP2013121977 A5 JP 2013121977A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- composition
- peptide
- conjugate
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 206010028980 Neoplasm Diseases 0.000 claims 8
- 201000011510 cancer Diseases 0.000 claims 6
- 235000014113 dietary fatty acids Nutrition 0.000 claims 6
- 239000000194 fatty acid Substances 0.000 claims 6
- 229930195729 fatty acid Natural products 0.000 claims 6
- 150000004665 fatty acids Chemical class 0.000 claims 6
- 125000000539 amino acid group Chemical group 0.000 claims 5
- 238000000034 method Methods 0.000 claims 4
- 230000036457 multidrug resistance Effects 0.000 claims 4
- 230000002265 prevention Effects 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- 238000011282 treatment Methods 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 238000011394 anticancer treatment Methods 0.000 claims 3
- 101150066553 MDR1 gene Proteins 0.000 claims 2
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 125000003277 amino group Chemical group 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 210000004556 brain Anatomy 0.000 claims 2
- 210000000481 breast Anatomy 0.000 claims 2
- 210000001072 colon Anatomy 0.000 claims 2
- 210000000936 intestine Anatomy 0.000 claims 2
- 210000003734 kidney Anatomy 0.000 claims 2
- 208000032839 leukemia Diseases 0.000 claims 2
- 239000002502 liposome Substances 0.000 claims 2
- 210000004185 liver Anatomy 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 229940035032 monophosphoryl lipid a Drugs 0.000 claims 2
- 201000000050 myeloid neoplasm Diseases 0.000 claims 2
- 210000002307 prostate Anatomy 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 210000003932 urinary bladder Anatomy 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 102000000589 Interleukin-1 Human genes 0.000 claims 1
- 108010002352 Interleukin-1 Proteins 0.000 claims 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 claims 1
- 238000011319 anticancer therapy Methods 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 239000001506 calcium phosphate Substances 0.000 claims 1
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 1
- 235000011010 calcium phosphates Nutrition 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 238000010511 deprotection reaction Methods 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 239000003094 microcapsule Substances 0.000 claims 1
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 1
- 239000000277 virosome Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0309188 | 2003-07-25 | ||
| FR0309188A FR2857875A1 (fr) | 2003-07-25 | 2003-07-25 | Vaccin therapeutique cible contre la p-glycoproteine 170 pour inhiber la resistance multidrogues dans le traitement des cancers |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006521498A Division JP2006528650A (ja) | 2003-07-25 | 2004-07-25 | 癌の治療における多剤耐性を抑制するための、ｐ−糖タンパク質１７０を標的とする治療ワクチン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013121977A JP2013121977A (ja) | 2013-06-20 |
| JP2013121977A5 true JP2013121977A5 (enExample) | 2014-01-09 |
Family
ID=33561147
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006521498A Pending JP2006528650A (ja) | 2003-07-25 | 2004-07-25 | 癌の治療における多剤耐性を抑制するための、ｐ−糖タンパク質１７０を標的とする治療ワクチン |
| JP2013018233A Withdrawn JP2013121977A (ja) | 2003-07-25 | 2013-02-01 | 癌の治療における多剤耐性を抑制するための、ｐ−糖タンパク質１７０を標的とする治療ワクチン |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006521498A Pending JP2006528650A (ja) | 2003-07-25 | 2004-07-25 | 癌の治療における多剤耐性を抑制するための、ｐ−糖タンパク質１７０を標的とする治療ワクチン |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060233758A1 (enExample) |
| EP (2) | EP1651257B1 (enExample) |
| JP (2) | JP2006528650A (enExample) |
| KR (2) | KR20060125676A (enExample) |
| CN (1) | CN1856323B (enExample) |
| AU (1) | AU2004262472B2 (enExample) |
| CA (1) | CA2533540C (enExample) |
| FR (1) | FR2857875A1 (enExample) |
| WO (1) | WO2005014036A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8663650B2 (en) * | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
| US7807171B2 (en) * | 2003-07-25 | 2010-10-05 | Ac Immune Sa | Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
| US20080026995A1 (en) * | 2003-07-25 | 2008-01-31 | Ac Immune Sa | Therapeutic vaccine targeted against p-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
| US8090392B2 (en) * | 2005-08-05 | 2012-01-03 | Interdigital Technology Corporation | Method and system for reporting a short message capability via an IP multimedia subsystem |
| US8273361B2 (en) | 2006-09-26 | 2012-09-25 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| KR101130754B1 (ko) * | 2010-06-25 | 2012-03-28 | 제일약품주식회사 | 난용성 트리사이클릭 유도체 화합물의 용해도가 향상된 약학적 조성물 |
| US9289488B2 (en) | 2010-08-12 | 2016-03-22 | Ac Immune Sa | Vaccine engineering |
| AR083561A1 (es) | 2010-10-26 | 2013-03-06 | Ac Immune Sa | Preparacion de una construccion antigenica |
| LT2850431T (lt) | 2012-05-16 | 2018-06-25 | Immune Design Corp. | Vakcinos, skirtos hsv-2 |
| KR102039520B1 (ko) | 2013-04-18 | 2019-11-01 | 이뮨 디자인 코포레이션 | 암 치료에 이용하기 위한 gla 단일요법 |
| CA3118692A1 (en) | 2018-11-06 | 2020-05-14 | Alsatech, Inc. | Cell-based gene therapy for neurodegenerative diseases |
| CN112687354B (zh) * | 2019-01-29 | 2022-07-12 | 杭州纽安津生物科技有限公司 | 针对靶向药物PI3K、AKT、mTOR通路的激酶抑制剂的多肽疫苗组合及其设计方法 |
| CN113648429B (zh) * | 2021-07-06 | 2023-11-10 | 中山大学 | 靶向肿瘤周围细胞激活免疫的聚合物及其制备方法与应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1257893B (it) * | 1992-06-17 | 1996-02-16 | Ist Superiore Sanita | Anticorpi monoclonali che riconoscono un epitopo della p-glicoproteina umana. |
| WO1994010198A1 (en) * | 1992-11-02 | 1994-05-11 | Yves Claude Nicolau | Method of reducing multidrug resistance in cells and tissues |
| JP3759759B2 (ja) * | 1994-03-04 | 2006-03-29 | 日本油脂株式会社 | リポソームおよび薬物運搬体 |
| JP4385152B2 (ja) * | 1997-09-17 | 2009-12-16 | 三菱化学株式会社 | ２価反応性水溶性高分子誘導体及びそれを含有する複合体 |
| JP2002047298A (ja) * | 2000-07-10 | 2002-02-12 | Academia Sinica | 新規抗がん剤伝達系 |
| US8663650B2 (en) * | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
| JP2007500218A (ja) * | 2003-05-12 | 2007-01-11 | アフィーマックス・インコーポレイテッド | ポリ（エチレングリコール）修飾ペプチド系化合物の新規スペーサー部分 |
-
2003
- 2003-07-25 FR FR0309188A patent/FR2857875A1/fr not_active Withdrawn
-
2004
- 2004-07-25 KR KR1020067001783A patent/KR20060125676A/ko not_active Ceased
- 2004-07-25 JP JP2006521498A patent/JP2006528650A/ja active Pending
- 2004-07-25 KR KR1020127033292A patent/KR20130008092A/ko not_active Ceased
- 2004-07-25 CA CA2533540A patent/CA2533540C/fr not_active Expired - Fee Related
- 2004-07-25 CN CN2004800274241A patent/CN1856323B/zh not_active Expired - Fee Related
- 2004-07-25 EP EP04763487.8A patent/EP1651257B1/fr not_active Expired - Lifetime
- 2004-07-25 EP EP10185331.5A patent/EP2316478B1/fr not_active Expired - Lifetime
- 2004-07-25 AU AU2004262472A patent/AU2004262472B2/en not_active Ceased
- 2004-07-25 WO PCT/EP2004/008330 patent/WO2005014036A1/fr not_active Ceased
-
2005
- 2005-11-16 US US11/274,885 patent/US20060233758A1/en not_active Abandoned
-
2013
- 2013-02-01 JP JP2013018233A patent/JP2013121977A/ja not_active Withdrawn
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