MX2012011668A - Peptidos cdca5 y vacunas que incluyen los mismos. - Google Patents
Peptidos cdca5 y vacunas que incluyen los mismos.Info
- Publication number
- MX2012011668A MX2012011668A MX2012011668A MX2012011668A MX2012011668A MX 2012011668 A MX2012011668 A MX 2012011668A MX 2012011668 A MX2012011668 A MX 2012011668A MX 2012011668 A MX2012011668 A MX 2012011668A MX 2012011668 A MX2012011668 A MX 2012011668A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- peptides
- nucleic acids
- substances
- compositions
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Se describen en la presente péptidos aislados derivados de SEQ ID NO: 21 y fragmentos de los mismos que enlazan a un antígeno HLA e inducen linfocitos T citotóxicos (CTL) y de esta manera son adecuados para uso en el contexto de inmunoterapia de cáncer, más particularmente vacunas para el cáncer. Los péptidos inventivos abarcan tanto las secuencias de aminoácidos mencionadas arriba y versiones modificadas de los mismos, en los cuales uno, dos, o. varios aminoácidos son sustituidos, eliminados, agregados o insertados, con tal de que tales versiones modificadas mantengan la capacidad de inducción de CTL y/o de enlace lILA. Se proporcionan además ácidos nucleicos que codifican cualquiera de los péptidos antes mencionados así como agentes, sustancias y/o composiciones farmacéuticas que incluyen o incorporan cualquiera de los péptidos o ácidos nucleicos antes mencionados. Los péptidos, ácidos nucleicos, agentes, sustancias y composiciones farmacéuticas de esta invención encuentran utilidad particular en el tratamiento de cánceres y tumores, que incluyen, por ejemplo, AML, cáncer de vejiga, cáncer de mama, cáncer cervical, carcinoma colangiocelular, CML, cáncer colorrectal, cáncer esofágico, cáncer gástrico, cáncer gástrico tipo difuso, cáncer de pulmón, linfoma, cáncer de próstata, SCLC, y tumor de tejido suave.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32267610P | 2010-04-09 | 2010-04-09 | |
PCT/JP2011/002078 WO2011125334A1 (en) | 2010-04-09 | 2011-04-07 | Cdca5 peptides and vaccines including the same |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012011668A true MX2012011668A (es) | 2012-12-17 |
Family
ID=44762304
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012011668A MX2012011668A (es) | 2010-04-09 | 2011-04-07 | Peptidos cdca5 y vacunas que incluyen los mismos. |
Country Status (14)
Country | Link |
---|---|
US (1) | US20130108664A1 (es) |
EP (1) | EP2556084A4 (es) |
JP (1) | JP2013523084A (es) |
KR (1) | KR20130043627A (es) |
CN (1) | CN102947325B (es) |
AU (1) | AU2011236397A1 (es) |
BR (1) | BR112012025567A2 (es) |
CA (1) | CA2795534A1 (es) |
MX (1) | MX2012011668A (es) |
RU (1) | RU2012147590A (es) |
SG (2) | SG183945A1 (es) |
TW (1) | TW201138806A (es) |
WO (1) | WO2011125334A1 (es) |
ZA (1) | ZA201207416B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112015012234A2 (pt) * | 2012-12-04 | 2017-08-15 | Oncotherapy Science Inc | Peptídios sema5b e vacinas contendo os mesmos |
WO2014106886A1 (en) * | 2013-01-07 | 2014-07-10 | Oncotherapy Science, Inc. | Cdca5 peptides and vaccines containing the same |
TW201636358A (zh) * | 2014-12-09 | 2016-10-16 | 腫瘤療法 科學股份有限公司 | 對於th1細胞之gpc3抗原決定位胜肽及含此之疫苗 |
CN107619835A (zh) * | 2017-05-11 | 2018-01-23 | 广东医科大学 | Cdca5在胃癌中的表达载体及其构建方法及cdca5在胃癌中特异干扰片段 |
FI3652606T3 (fi) * | 2017-07-12 | 2023-03-16 | Nouscom Ag | Jaettuihin tuumorineoantigeeneihin perustuva yleisrokote epästabiilien mikrosatelliitti (msi) -syöpien ennaltaehkäisyyn ja hoitoon |
CN109355394A (zh) * | 2018-12-28 | 2019-02-19 | 江苏省人民医院(南京医科大学第附属医院) | 癌-睾丸抗原cdca5作为食管鳞癌预后标志物及治疗靶点 |
HUE065269T2 (hu) * | 2019-05-29 | 2024-05-28 | Hubro Therapeutics As | Peptidek |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2450067A1 (en) * | 2001-06-15 | 2002-12-27 | Incyte Genomics, Inc. | Proteins associated with cell growth, differentiation, and death |
JP2003135075A (ja) * | 2001-11-05 | 2003-05-13 | Research Association For Biotechnology | 新規な全長cDNA |
EP2267023B1 (en) * | 2002-09-12 | 2015-02-11 | Oncotherapy Science, Inc. | KDR peptides and vaccines comprising the same |
TWI434853B (zh) * | 2007-04-11 | 2014-04-21 | Oncotherapy Science Inc | 腫瘤血管內皮標誌8胜肽及包含此胜肽之疫苗 |
RU2010111135A (ru) * | 2007-08-24 | 2011-10-27 | Онкотерапи Сайенс, Инк. (Jp) | Связанные со злокачественными опухолями гены cdca5. epha7. stk31 и wdhd1 |
TW200932260A (en) * | 2007-11-28 | 2009-08-01 | Oncotherapy Science Inc | STAT3 epitope peptides |
-
2011
- 2011-04-07 SG SG2012066221A patent/SG183945A1/en unknown
- 2011-04-07 CA CA2795534A patent/CA2795534A1/en not_active Abandoned
- 2011-04-07 MX MX2012011668A patent/MX2012011668A/es not_active Application Discontinuation
- 2011-04-07 CN CN201180028644.6A patent/CN102947325B/zh not_active Expired - Fee Related
- 2011-04-07 RU RU2012147590/10A patent/RU2012147590A/ru not_active Application Discontinuation
- 2011-04-07 BR BR112012025567A patent/BR112012025567A2/pt not_active IP Right Cessation
- 2011-04-07 AU AU2011236397A patent/AU2011236397A1/en not_active Abandoned
- 2011-04-07 KR KR1020127028423A patent/KR20130043627A/ko not_active Application Discontinuation
- 2011-04-07 WO PCT/JP2011/002078 patent/WO2011125334A1/en active Application Filing
- 2011-04-07 JP JP2012546271A patent/JP2013523084A/ja not_active Withdrawn
- 2011-04-07 EP EP11765236.2A patent/EP2556084A4/en not_active Withdrawn
- 2011-04-07 US US13/639,935 patent/US20130108664A1/en not_active Abandoned
- 2011-04-07 SG SG10201502791YA patent/SG10201502791YA/en unknown
- 2011-04-08 TW TW100112188A patent/TW201138806A/zh unknown
-
2012
- 2012-10-03 ZA ZA2012/07416A patent/ZA201207416B/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20130043627A (ko) | 2013-04-30 |
CN102947325B (zh) | 2015-04-01 |
CA2795534A1 (en) | 2011-10-13 |
CN102947325A (zh) | 2013-02-27 |
JP2013523084A (ja) | 2013-06-17 |
US20130108664A1 (en) | 2013-05-02 |
RU2012147590A (ru) | 2014-05-20 |
WO2011125334A1 (en) | 2011-10-13 |
AU2011236397A1 (en) | 2012-11-01 |
EP2556084A1 (en) | 2013-02-13 |
SG10201502791YA (en) | 2015-05-28 |
BR112012025567A2 (pt) | 2019-09-24 |
ZA201207416B (en) | 2013-06-26 |
SG183945A1 (en) | 2012-10-30 |
TW201138806A (en) | 2011-11-16 |
EP2556084A4 (en) | 2013-08-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |