AU2006301891B2 - Use of liposomes in a carrier comprising a continuous hydrophobic phase as a vehicle for cancer treatment - Google Patents

Use of liposomes in a carrier comprising a continuous hydrophobic phase as a vehicle for cancer treatment Download PDF

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Publication number
AU2006301891B2
AU2006301891B2 AU2006301891A AU2006301891A AU2006301891B2 AU 2006301891 B2 AU2006301891 B2 AU 2006301891B2 AU 2006301891 A AU2006301891 A AU 2006301891A AU 2006301891 A AU2006301891 A AU 2006301891A AU 2006301891 B2 AU2006301891 B2 AU 2006301891B2
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composition
peptide
seq
liposomes
mice
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AU2006301891A
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AU2006301891A1 (en
Inventor
Robert G. Brown
Pirouz M. Daftarian
Wijbe M. Kast
Marc Mansour
Bill Pohajdak
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Immunovaccine Technologies Inc
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Immunovaccine Technologies Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
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    • A01K2267/0331—Animal model for proliferative diseases
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    • A—HUMAN NECESSITIES
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    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
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  • General Engineering & Computer Science (AREA)
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  • Toxicology (AREA)
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AU2006301891A 2005-10-07 2006-10-05 Use of liposomes in a carrier comprising a continuous hydrophobic phase as a vehicle for cancer treatment Ceased AU2006301891B2 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CA002523032A CA2523032A1 (en) 2005-10-07 2005-10-07 Vaccines for cancer therapy
CA2,523,032 2005-10-07
CA2,533,705 2006-01-13
CA002533705A CA2533705A1 (en) 2005-10-07 2006-01-13 Use of liposomes in a water-in-oil emulsion or in a continuous hydrophobic carrier as a vehicle for cancer treatment
CA002542212A CA2542212A1 (en) 2005-10-07 2006-04-07 Use of liposomes in a water-in-oil emulsion or in a continuous hydrophobic carrier as a vehicle for cancer treatment
CA2,542,212 2006-04-07
US80657306P 2006-07-05 2006-07-05
US60/806,573 2006-07-05
PCT/CA2006/001640 WO2007041832A1 (en) 2005-10-07 2006-10-05 Use of liposomes in a carrier comprising a continuous hydrophobic phase as a vehicle for cancer treatment

Publications (2)

Publication Number Publication Date
AU2006301891A1 AU2006301891A1 (en) 2007-04-19
AU2006301891B2 true AU2006301891B2 (en) 2012-09-06

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AU2006301891A Ceased AU2006301891B2 (en) 2005-10-07 2006-10-05 Use of liposomes in a carrier comprising a continuous hydrophobic phase as a vehicle for cancer treatment

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US (3) US20090297593A1 (enExample)
EP (1) EP1948225B1 (enExample)
JP (1) JP5528703B2 (enExample)
CN (1) CN101282742B (enExample)
AU (1) AU2006301891B2 (enExample)
CA (4) CA2523032A1 (enExample)
ES (1) ES2451599T3 (enExample)
WO (1) WO2007041832A1 (enExample)

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US9090673B2 (en) * 2003-12-12 2015-07-28 City Of Hope Synthetic conjugate of CpG DNA and T-help/CTL peptide
CA2523032A1 (en) 2005-10-07 2007-04-07 Immunovaccine Technologies Inc. Vaccines for cancer therapy
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AU2008307042B2 (en) * 2007-10-03 2014-01-30 Immunovaccine Technologies Inc. Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof
CA2723918C (en) * 2008-06-05 2018-01-09 Immunovaccine Technologies Inc. Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance
US9624284B2 (en) * 2011-09-13 2017-04-18 Immunotope, Inc. Cytotoxic T lymphocyte inducing immunogens for prevention treatment and diagnosis of cancer
IN2014CN02581A (enExample) * 2011-10-06 2015-08-07 Immunovaccine Technologies Inc
CA2840997A1 (en) * 2013-02-05 2014-08-05 Nitto Denko Corporation Vaccine composition for transdermal administration
WO2014153636A1 (en) 2013-03-27 2014-10-02 Immunovaccine Technologies Inc. Method for improving the efficacy of a survivin vaccine in the treatment of cancer
EP3164135B1 (en) * 2014-07-02 2019-10-23 David Lembo Oxysterols for use in the treatment and prevention of diseases caused by viruses
WO2016021605A1 (ja) * 2014-08-04 2016-02-11 日東電工株式会社 Ｃｔｌのアポトーシスを抑制するまたｃｔｌの誘導抑制を阻害するワクチン医薬組成物
WO2016109880A1 (en) 2015-01-06 2016-07-14 Immunovaccine Technologies Inc. Lipid a mimics, methods of preparation, and uses thereof
US20180162913A1 (en) * 2015-05-01 2018-06-14 Immunovaccine Technologies Inc. Methods for potentiating an immune response using depot-forming and non-depot-forming vaccines
US11160861B2 (en) 2015-11-18 2021-11-02 Immunovaccine Technologies Inc. Adjuvanting systems and water-free vaccine compositions comprising a polyI:C polynucleotide adjuvant and a lipid-based adjuvant
CN109328070A (zh) 2016-05-04 2019-02-12 免疫疫苗技术有限公司 包含两亲化合物、新抗原和疏水载体的疫苗组合物及其使用方法
SG11201808552XA (en) 2016-05-18 2018-10-30 Cue Biopharma Inc T-cell modulatory multimeric polypeptides and methods of use thereof
JP7125197B2 (ja) 2016-09-27 2022-08-24 イミューノヴァクシーン テクノロジーズ インコーポレイテッド ヒト対象において抗体免疫応答を誘導するために低投与体積ｂ細胞エピトープ組成物を使用する方法
CN110325205B (zh) * 2016-12-22 2023-08-15 库尔生物制药有限公司 T细胞调节性多聚体多肽及其使用方法
US11851471B2 (en) 2017-01-09 2023-12-26 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
KR20240005989A (ko) 2017-03-15 2024-01-12 큐 바이오파마, 인크. 면역 반응을 조절하는 방법
WO2019139896A1 (en) 2018-01-09 2019-07-18 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof
EP3768242A4 (en) * 2018-03-20 2021-12-08 ImmunoVaccine Technologies Inc. METHODS AND COMPOSITIONS FOR THE TARGETED DELIVERY OF ACTIVE SUBSTANCES AND IMMUNMODULATORY AGENTS TO LYMPH NODES
IL296209A (en) 2020-05-12 2022-11-01 Cue Biopharma Inc Multimeric t-cell modulatory polypeptides and methods of using them
JP2023541366A (ja) 2020-09-09 2023-10-02 キュー バイオファーマ， インコーポレイテッド １型真性糖尿病（ｔ１ｄ）を治療するためのｍｈｃクラスｉｉ ｔ細胞調節多量体ポリペプチド及びその使用方法
CN116531498A (zh) * 2023-04-11 2023-08-04 金宇保灵生物药品有限公司 一种免疫增强剂、制备方法及其应用

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