JP2009510064A5 - - Google Patents
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- JP2009510064A5 JP2009510064A5 JP2008533434A JP2008533434A JP2009510064A5 JP 2009510064 A5 JP2009510064 A5 JP 2009510064A5 JP 2008533434 A JP2008533434 A JP 2008533434A JP 2008533434 A JP2008533434 A JP 2008533434A JP 2009510064 A5 JP2009510064 A5 JP 2009510064A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- pain
- use according
- disorder
- diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72152705P | 2005-09-29 | 2005-09-29 | |
| PCT/US2006/036423 WO2007040982A1 (en) | 2005-09-29 | 2006-09-20 | 5- (phenylisoxazolylethoxy) -triazol- 3 -yl substituted pyridine compounds for the treatment of neurological, psychiatric or pain disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009211258A Division JP2010013476A (ja) | 2005-09-29 | 2009-09-14 | 神経障害、精神障害または疼痛性障害の処置用の新規化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009510064A JP2009510064A (ja) | 2009-03-12 |
| JP2009510064A5 true JP2009510064A5 (https=) | 2009-11-05 |
Family
ID=37745801
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008533434A Pending JP2009510064A (ja) | 2005-09-29 | 2006-09-20 | 神経障害、精神障害または疼痛性障害の処置用の新規化合物 |
| JP2009211258A Pending JP2010013476A (ja) | 2005-09-29 | 2009-09-14 | 神経障害、精神障害または疼痛性障害の処置用の新規化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009211258A Pending JP2010013476A (ja) | 2005-09-29 | 2009-09-14 | 神経障害、精神障害または疼痛性障害の処置用の新規化合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US7476684B2 (https=) |
| EP (1) | EP1934209A1 (https=) |
| JP (2) | JP2009510064A (https=) |
| KR (1) | KR20080050421A (https=) |
| CN (1) | CN101273037A (https=) |
| AR (1) | AR058807A1 (https=) |
| AU (1) | AU2006297462A1 (https=) |
| BR (1) | BRPI0616228A2 (https=) |
| CA (1) | CA2623009A1 (https=) |
| EC (1) | ECSP088283A (https=) |
| IL (1) | IL189990A0 (https=) |
| NO (1) | NO20081434L (https=) |
| RU (1) | RU2008108219A (https=) |
| TW (1) | TW200800976A (https=) |
| UA (1) | UA92503C2 (https=) |
| UY (1) | UY29796A1 (https=) |
| WO (1) | WO2007040982A1 (https=) |
| ZA (1) | ZA200802163B (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL166510A0 (en) * | 2002-08-09 | 2006-01-15 | Nps Pharma Inc | 1,2,4"oxadiazole as modulators of metabotropic glutamate receptor-5 |
| US7585881B2 (en) * | 2004-02-18 | 2009-09-08 | Astrazeneca Ab | Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| AR058807A1 (es) * | 2005-09-29 | 2008-02-27 | Astrazeneca Ab | 5-(fenilisoxazoletoxi)-triazol-3-il piridinas sustituidas, para el tratamiento de trastornos mediados por el receptor mglur5 |
| TW200821305A (en) * | 2006-10-05 | 2008-05-16 | Astrazeneca Ab | MGluR5 modulators |
| PE20090875A1 (es) | 2007-10-19 | 2009-08-08 | Astrazeneca Ab | Derivados de tetrazol como moduladores de los receptores de glutamato metabotropicos |
| EP2212316A4 (en) * | 2007-10-26 | 2012-06-27 | Astrazeneca Ab | DERIVATIVES OF AMINO1,2,4-TRIAZOLES AS MODULATORS OF MGLUR5 |
| WO2010019101A1 (en) * | 2008-08-12 | 2010-02-18 | Astrazeneca Ab | A crystalline form of 4- (5-{ (ir) -1- [5- (3- chlorophenyl) isoxazol-3-yl] ethoxy } - 4 -methyl- 4h- 1, 2,4- triazol-3-yl) pyridine |
| CN102176910A (zh) * | 2008-08-12 | 2011-09-07 | 阿斯利康(瑞典)有限公司 | 4-(5-{(1r)-1-[5-(3-氯苯基)异噁唑-3-基]乙氧基}-4-甲基-4h-1,2,4-三唑-3-基)吡啶的新晶体形式 |
| CA2751761A1 (en) * | 2008-10-22 | 2010-04-29 | House Ear Institute | Treatment and/or prevention of inner ear conditions by modulation of a metabotropic glutamate receptor |
| MX2011005981A (es) * | 2008-12-12 | 2011-06-27 | Astrazeneca Ab | Nuevo proceso para preparar 4-[4-metil-5-(alquiltio c1-10/aril c5-10-alquilto c1-6)-4h-1,2,4-triazol-3-il]piridinas. |
| KR20110101164A (ko) * | 2008-12-18 | 2011-09-15 | 아스트라제네카 아베 | 1-〔5-(3-클로로-페닐)-이소옥사졸-3-일〕-에타논 및 (ｒ)-1-〔5-(3-클로로-페닐)-이속사졸-3-일〕-에탄올의 신규 제조 방법 |
| EP2379531A1 (en) * | 2008-12-18 | 2011-10-26 | AstraZeneca AB | Processes for the manufacture of 3-{4-methyl-5- [ (ir) -1- (2- (3-methylphenyl) -2h-tetrazol-5-yl) -ethoxy]-4h- [1,2, 4]triazol-3-yl} -pyridine, 4-methyl-3-methylthio-5- (3- pyridyl)-l,2,4-triazole, and (ir) -1- [2- (3-methylphenyl) -2h- tetrazol-5-yl]ethanol |
| US8349852B2 (en) | 2009-01-13 | 2013-01-08 | Novartis Ag | Quinazolinone derivatives useful as vanilloid antagonists |
| WO2010139966A1 (en) * | 2009-06-05 | 2010-12-09 | Oslo University Hospital Hf | Azole derivatives as wtn pathway inhibitors |
| ES2443578T3 (es) | 2009-12-29 | 2014-02-19 | Eli Lilly And Company | Compuestos de tetrahidrotriazolopiridina como potenciadores de receptores selectivos de mGlu5 útiles para el tratamiento de la esquizofrenia |
| WO2011092290A1 (en) | 2010-02-01 | 2011-08-04 | Novartis Ag | Pyrazolo[5,1b]oxazole derivatives as crf-1 receptor antagonists |
| AR080056A1 (es) | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
| EP2531490B1 (en) | 2010-02-02 | 2014-10-15 | Novartis AG | Cyclohexyl amide derivatives as crf receptor antagonists |
| US8080568B1 (en) * | 2010-06-29 | 2011-12-20 | Ewha University - Industry Collaboration Foundation | 2-pyridyl substituted imidazoles as therapeutic ALK5 and/or ALK4 inhibitors |
| UA112418C2 (uk) * | 2010-09-07 | 2016-09-12 | Астеллас Фарма Інк. | Терапевтичний болезаспокійливий засіб |
| JP2013544874A (ja) | 2010-12-08 | 2013-12-19 | オスロ ユニヴァーシティー ホスピタル エイチエフ | Ｗｎｔシグナル伝達経路阻害薬としてのトリアゾール誘導体 |
| WO2012127393A1 (en) | 2011-03-18 | 2012-09-27 | Novartis Ag | COMBINATIONS OF ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVATORS AND mGluR5 ANTAGONISTS FOR USE IN DOPAMINE INDUCED DYSKINESIA IN PARKINSON'S DISEASE |
| KR20160120157A (ko) | 2015-04-07 | 2016-10-17 | 주식회사 메드팩토 | 암 예방 또는 치료용 약학적 조성물 및 이를 이용한 방법 |
| WO2016163754A1 (en) * | 2015-04-07 | 2016-10-13 | Medpacto Inc. | Pharmaceutical composition for preventing or treating cancer and method using thereof |
| KR102027368B1 (ko) * | 2018-05-29 | 2019-10-01 | 서울대학교산학협력단 | 통증의 강도를 측정하는 방법 |
| CN113329754A (zh) | 2018-11-20 | 2021-08-31 | 麻雀制药股份有限公司 | 用于施用皮质类固醇的方法 |
| CN113811297B (zh) * | 2019-05-15 | 2024-03-26 | 克拉斯·图林 | 用于预防和/或治疗动物中的疼痛的4-[5-[(rac)-1-[5-(3-氯苯基)-3-异噁唑基]乙氧基]-4-甲基-4H-1,2,4-三唑-3-基]吡啶 |
| BR112022005579A2 (pt) * | 2019-11-05 | 2022-06-21 | Claes Thulin | 4-[5-[(rac)-1-[5-(3-clorofenil)-3-isoxazolil]etoxi]-4-metil-4h-1,2,4-triazol-3-il]piridina para uso na prevenção e/ou no tratamento de surmenage em um mamífero |
| EP4525983A4 (en) | 2022-05-16 | 2025-09-03 | Sparrow Pharmaceuticals Inc | METHODS AND COMPOSITIONS FOR TREATING GLUCOCORTICOID EXCESS |
| WO2024088712A1 (en) | 2022-10-28 | 2024-05-02 | Orphelion Ab | Mglur5 receptor antagonists for use in prevention and/or treatment of bone marrow lesions (bml) and/or osteoporosis, cartilage loss, osteosclerosis, osteitis in a mammal |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ517221A (en) | 1999-08-19 | 2004-01-30 | Nps Pharma Inc | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| CN1853630A (zh) * | 2001-02-21 | 2006-11-01 | Nps制药公司 | 杂多环化合物及其在亲代谢的谷氨酸受体拮抗剂中的应用 |
| IL166510A0 (en) * | 2002-08-09 | 2006-01-15 | Nps Pharma Inc | 1,2,4"oxadiazole as modulators of metabotropic glutamate receptor-5 |
| MXPA05001592A (es) | 2002-08-09 | 2005-05-05 | Astrazeneca Ab | Oxadiazoles como moduladores de receptor-5 de glutamato metabotropico. |
| AU2003264018A1 (en) | 2002-08-09 | 2004-02-25 | Astrazeneca Ab | Compounds having an activity at metabotropic glutamate receptors |
| WO2005060971A1 (en) | 2003-12-18 | 2005-07-07 | Astrazeneca Ab | Treatment of reflux-related diseases |
| BRPI0417308A (pt) | 2003-12-19 | 2007-09-11 | Astrazeneca Ab | compostos, respectivo uso, composição farmacêutica, métodos de tratamento de distúrbios mediados pelo receptor mglur5 e de inibição da ativação de receptores mglur5 e processo de produção de compostos de piridila |
| WO2005077368A2 (en) * | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
| WO2005077345A1 (en) | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Compounds for the treatment of gastro-esophageal reflux disease |
| DK1716152T3 (da) | 2004-02-18 | 2008-11-03 | Astrazeneca Ab | Kondenserade heterocykliske forbindelser og deres anvendelse som metabotrope receptorantagonister til behandling af gastrointentinde lidelser |
| US7585881B2 (en) * | 2004-02-18 | 2009-09-08 | Astrazeneca Ab | Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| RU2381226C2 (ru) | 2004-02-18 | 2010-02-10 | Астразенека Аб | Полигетероциклические соединения и их применение в качестве антагонистов метаботропного рецептора глутамата |
| EP1720860A1 (en) | 2004-02-18 | 2006-11-15 | AstraZeneca AB | Triazole compounds and their use as metabotropic glutamate receptor antagonists |
| BRPI0507499A (pt) | 2004-02-18 | 2007-07-24 | Astrazeneca Ab | composto ou um sal farmaceuticamente aceitável ou hidrato dos mesmos, composição farmacêutica, uso do composto, e, métodos para tratar distúrbios mediados por mglur 5 e para inibir a ativação de receptores de mglur 5 |
| TW200533664A (en) | 2004-02-18 | 2005-10-16 | Astrazeneca Ab | Tetrazole compounds and their use as metabotropic glutamate receptor antagonists |
| AR058807A1 (es) * | 2005-09-29 | 2008-02-27 | Astrazeneca Ab | 5-(fenilisoxazoletoxi)-triazol-3-il piridinas sustituidas, para el tratamiento de trastornos mediados por el receptor mglur5 |
-
2006
- 2006-09-15 AR ARP060104038A patent/AR058807A1/es not_active Application Discontinuation
- 2006-09-15 UY UY29796A patent/UY29796A1/es not_active Application Discontinuation
- 2006-09-19 TW TW095134584A patent/TW200800976A/zh unknown
- 2006-09-20 CA CA002623009A patent/CA2623009A1/en not_active Abandoned
- 2006-09-20 US US11/523,717 patent/US7476684B2/en not_active Expired - Fee Related
- 2006-09-20 UA UAA200802884A patent/UA92503C2/ru unknown
- 2006-09-20 RU RU2008108219/04A patent/RU2008108219A/ru not_active Application Discontinuation
- 2006-09-20 JP JP2008533434A patent/JP2009510064A/ja active Pending
- 2006-09-20 EP EP06803836A patent/EP1934209A1/en not_active Withdrawn
- 2006-09-20 WO PCT/US2006/036423 patent/WO2007040982A1/en not_active Ceased
- 2006-09-20 BR BRPI0616228-2A patent/BRPI0616228A2/pt not_active IP Right Cessation
- 2006-09-20 AU AU2006297462A patent/AU2006297462A1/en not_active Abandoned
- 2006-09-20 US US12/067,270 patent/US20080227824A1/en not_active Abandoned
- 2006-09-20 KR KR1020087006537A patent/KR20080050421A/ko not_active Withdrawn
- 2006-09-20 CN CNA2006800343984A patent/CN101273037A/zh active Pending
-
2007
- 2007-07-27 US US11/829,866 patent/US20070270468A1/en not_active Abandoned
- 2007-07-27 US US11/829,867 patent/US20070270469A1/en not_active Abandoned
-
2008
- 2008-03-06 IL IL189990A patent/IL189990A0/en unknown
- 2008-03-07 ZA ZA200802163A patent/ZA200802163B/xx unknown
- 2008-03-14 EC EC2008008283A patent/ECSP088283A/es unknown
- 2008-03-19 NO NO20081434A patent/NO20081434L/no not_active Application Discontinuation
-
2009
- 2009-09-14 JP JP2009211258A patent/JP2010013476A/ja active Pending