JP2012500245A5 - - Google Patents

Download PDF

Info

Publication number
JP2012500245A5
JP2012500245A5 JP2011523405A JP2011523405A JP2012500245A5 JP 2012500245 A5 JP2012500245 A5 JP 2012500245A5 JP 2011523405 A JP2011523405 A JP 2011523405A JP 2011523405 A JP2011523405 A JP 2011523405A JP 2012500245 A5 JP2012500245 A5 JP 2012500245A5
Authority
JP
Japan
Prior art keywords
formula
pharmaceutically acceptable
hydromethanesulfonate
hydromaleate
hydrofumarate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011523405A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012500245A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2009/060592 external-priority patent/WO2010020602A1/en
Publication of JP2012500245A publication Critical patent/JP2012500245A/ja
Publication of JP2012500245A5 publication Critical patent/JP2012500245A5/ja
Pending legal-status Critical Current

Links

JP2011523405A 2008-08-19 2009-08-17 経皮的インターベンション心臓カテーテル法のためのダビガトラン Pending JP2012500245A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9001808P 2008-08-19 2008-08-19
US61/090,018 2008-08-19
PCT/EP2009/060592 WO2010020602A1 (en) 2008-08-19 2009-08-17 Dabigatran for percutaneous interventional cardiac catheterisation

Publications (2)

Publication Number Publication Date
JP2012500245A JP2012500245A (ja) 2012-01-05
JP2012500245A5 true JP2012500245A5 (https=) 2012-10-04

Family

ID=41258283

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011523405A Pending JP2012500245A (ja) 2008-08-19 2009-08-17 経皮的インターベンション心臓カテーテル法のためのダビガトラン

Country Status (19)

Country Link
US (1) US20110301201A1 (https=)
EP (1) EP2328580A1 (https=)
JP (1) JP2012500245A (https=)
KR (1) KR20110044230A (https=)
CN (1) CN102123707A (https=)
AR (1) AR073077A1 (https=)
AU (1) AU2009284217A1 (https=)
BR (1) BRPI0917507A2 (https=)
CA (1) CA2734794A1 (https=)
CL (1) CL2011000361A1 (https=)
CO (1) CO6290686A2 (https=)
EA (1) EA201100358A1 (https=)
EC (1) ECSP11010825A (https=)
IL (1) IL210005A0 (https=)
MA (1) MA32563B1 (https=)
MX (1) MX2011001612A (https=)
NZ (1) NZ591108A (https=)
TW (1) TW201022235A (https=)
WO (1) WO2010020602A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013510072A (ja) 2008-11-11 2013-03-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 従来のワルファリン治療に対して安全性プロフィールが改善されたダビガトランエテキシレートまたはその塩を使用して血栓症を治療または予防するための方法
EP2542224B1 (en) * 2010-03-01 2014-08-13 Ratiopharm GmbH Dabigatran etexilate-containing oral pharmaceutical composition
JP6155187B2 (ja) 2010-03-30 2017-06-28 ヴァーセオン コーポレイション トロンビンの阻害剤としての多置換芳香族化合物
CN102391250B (zh) * 2011-08-29 2013-06-19 石药集团欧意药业有限公司 一种达比加群酯化合物、制备方法及其药物组合物
CN102558153A (zh) * 2012-02-08 2012-07-11 北京阜康仁生物制药科技有限公司 达比加群酯的新药用盐及其制备方法
CN103420984B (zh) * 2012-05-24 2015-07-08 天津药物研究院 作为前药的达比加群酯衍生物及其制备方法和用途
CN103420982B (zh) * 2012-05-24 2015-07-08 天津药物研究院 达比加群酯衍生物及其制备方法和用途
CN103420994B (zh) * 2012-05-24 2016-04-06 天津药物研究院 作为前药的达比加群酯衍生物及其制备方法和用途
CN103420985B (zh) * 2012-05-24 2015-09-23 天津药物研究院 作为前药的达比加群酯衍生物及其制备方法和用途
CN103524559B (zh) * 2012-07-05 2016-09-28 西藏海思科药业集团股份有限公司 多取代4-甲氨基苯甲脒的酯衍生物及其制备方法和用途
CN103539779B (zh) * 2012-07-13 2016-12-21 四川海思科制药有限公司 一种达比加群酯的羟基取代苯磺酸盐及其制备方法和用途
EP2900652A2 (en) * 2012-09-28 2015-08-05 Ranbaxy Laboratories Limited Process for the preparation of dabigatran etexilate or pharmaceutically acceptable salt thereof
US9399616B2 (en) 2012-10-22 2016-07-26 Boehringer Ingelheim International Gmbh Process for the manufacture of 4-aminobenzoamidine dihydrochloride
HK1214252A1 (zh) 2013-03-15 2016-07-22 Verseon Corporation 作為凝血酶抑制劑的鹵代吡唑
CN110179795A (zh) 2013-03-15 2019-08-30 维颂公司 作为丝氨酸蛋白酶抑制剂的多取代芳族化合物的制药用途
US10189810B2 (en) 2014-09-17 2019-01-29 Verseon Corporation Pyrazolyl-substituted pyridone compounds as serine protease inhibitors
CN107405333A (zh) 2015-02-27 2017-11-28 维颂公司 作为丝氨酸蛋白酶抑制剂的被取代的吡唑化合物
CN113164765B (zh) 2018-07-13 2026-03-20 维颂国际公司 凝血酶抑制剂、制剂及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101005716B1 (ko) * 2002-03-07 2011-01-05 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 ３－［（２－｛［４－（헥실옥시카보닐아미노－이미노-메틸）－페닐아미노］－메틸｝－１－메틸－１ｈ－벤즈이미다졸－５－카보닐）－피리딘－２－일－아미노］ 프로피온산 에틸에스테르의 경구 투여 형태
WO2006045756A1 (en) * 2004-10-25 2006-05-04 Boehringer Ingelheim International Gmbh Use of dipyridamole in combination with antithrombotics for treatment and prevention of thromboembolic diseases
CA2657266A1 (en) * 2006-07-17 2008-01-24 Boehringer Ingelheim International Gmbh New indications for direct thrombin inhibitors in the cardiovascular field
CL2007002067A1 (es) * 2006-07-17 2008-01-25 Boehringer Ingelheim Int Uso de dabigatran etexilato, inhibidores directos de la trombina, para el tratamiento y/o profilaxis en niños de enfermedades tales como infarto cerebral no hemorragico, infarto de miocardio, arritmia, trombosis venosa central, entre otras.
WO2008043759A1 (en) * 2006-10-10 2008-04-17 Boehringer Ingelheim International Gmbh Physiologically acceptable salts of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1h-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester

Similar Documents

Publication Publication Date Title
JP2012500245A5 (https=)
US9809545B2 (en) Factor XIa inhibitors
US20210221793A1 (en) Pyrazole derivatives as sgc stimulators
JP2007537187A5 (https=)
CA2674436A1 (en) Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
TWI388345B (zh) 用於高血壓之預防或治療之包含血管緊張素ⅱ受體拮抗劑及鈣通道阻斷劑之固體劑型
NZ595829A (en) 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl[1,2,4]triazolo[3,4-f]-1,6-naphthyridine derivatives
JP2009514837A5 (https=)
US20080200514A1 (en) Indications for Direct Thrombin Inhibitors
JP2010515715A5 (https=)
US20190161469A1 (en) Antifungal Compound Process
KR101775304B1 (ko) 퀴놀론 화합물의 제조 방법
JP2006523216A5 (https=)
NZ592508A (en) Pyrazine compounds as phosphodiesterase 10 inhibitors
JP2014037426A5 (https=)
US20150299198A1 (en) Inhibitors of the Renal Outer Medullary Potassium Channel
JP2009510064A5 (https=)
JP2010516700A5 (https=)
CN115315423A (zh) 取代芳基类化合物
WO2008009210A8 (fr) Composés de dihydropyrimidine optiquement purs et leurs utilisations dans la fabrication d'un médicament pour traiter ou prévenir des viroses
EP2765860A1 (en) Mineralocorticoid receptor antagonists
US20250243228A1 (en) PHOSPHORUS PRODRUGS OF PYRAZOLO-SUBSTITUTED PYRIMIDINE sGC STIMULATORS
JP2009511450A5 (https=)
JP2009543844A (ja) 直接トロンビン阻害剤の新しい小児適応症
JP2011500575A5 (https=)