JP2009510064A - 神経障害、精神障害または疼痛性障害の処置用の新規化合物 - Google Patents

神経障害、精神障害または疼痛性障害の処置用の新規化合物 Download PDF

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JP2009510064A
JP2009510064A JP2008533434A JP2008533434A JP2009510064A JP 2009510064 A JP2009510064 A JP 2009510064A JP 2008533434 A JP2008533434 A JP 2008533434A JP 2008533434 A JP2008533434 A JP 2008533434A JP 2009510064 A JP2009510064 A JP 2009510064A
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disease
pain
use according
disorder
compound
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JP2009510064A5 (https=
Inventor
ミニディス，アレクサンダー
ウェンスボ，デイヴィッド
スラッシ，アブデルマリック
アイザック，メスヴィン
エリックソン，キャロライン
プロフィア，ベロニカ
バーグストロム，パー−オロブ
エドワーズ，ルイーズ
アロラ，ジャライ
ジン，タオ
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AstraZeneca AB
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AstraZeneca AB
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
JP2008533434A 2005-09-29 2006-09-20 神経障害、精神障害または疼痛性障害の処置用の新規化合物 Pending JP2009510064A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72152705P 2005-09-29 2005-09-29
PCT/US2006/036423 WO2007040982A1 (en) 2005-09-29 2006-09-20 5- (phenylisoxazolylethoxy) -triazol- 3 -yl substituted pyridine compounds for the treatment of neurological, psychiatric or pain disorders

Related Child Applications (1)

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JP2009211258A Division JP2010013476A (ja) 2005-09-29 2009-09-14 神経障害、精神障害または疼痛性障害の処置用の新規化合物

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JP2009510064A true JP2009510064A (ja) 2009-03-12
JP2009510064A5 JP2009510064A5 (https=) 2009-11-05

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JP2008533434A Pending JP2009510064A (ja) 2005-09-29 2006-09-20 神経障害、精神障害または疼痛性障害の処置用の新規化合物
JP2009211258A Pending JP2010013476A (ja) 2005-09-29 2009-09-14 神経障害、精神障害または疼痛性障害の処置用の新規化合物

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JP2009211258A Pending JP2010013476A (ja) 2005-09-29 2009-09-14 神経障害、精神障害または疼痛性障害の処置用の新規化合物

Country Status (18)

Country Link
US (4) US7476684B2 (https=)
EP (1) EP1934209A1 (https=)
JP (2) JP2009510064A (https=)
KR (1) KR20080050421A (https=)
CN (1) CN101273037A (https=)
AR (1) AR058807A1 (https=)
AU (1) AU2006297462A1 (https=)
BR (1) BRPI0616228A2 (https=)
CA (1) CA2623009A1 (https=)
EC (1) ECSP088283A (https=)
IL (1) IL189990A0 (https=)
NO (1) NO20081434L (https=)
RU (1) RU2008108219A (https=)
TW (1) TW200800976A (https=)
UA (1) UA92503C2 (https=)
UY (1) UY29796A1 (https=)
WO (1) WO2007040982A1 (https=)
ZA (1) ZA200802163B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022532869A (ja) * 2019-05-15 2022-07-20 スーリン、クラース 動物の疼痛の予防及び／又は治療に使用するための４－［５－［（ｒａｃ）－１－［５－（３－クロロフェニル）－３－イソキサゾリル］エトキシ］－４－メチル－４ｈ－１，２，４－トリアゾール－３－イル］ピリジン
JP2023501114A (ja) * 2019-11-05 2023-01-18 スーリン、クラース 哺乳動物の過労の予防及び／又は治療に使用するための４－［５－［（ｒａｃ）－１－［５－（３－クロロフェニル）－３－イソキサゾリル］エトキシ］－４－メチル－４ｈ－１，２，４－トリアゾール－３－イル］ピリジン

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US7585881B2 (en) * 2004-02-18 2009-09-08 Astrazeneca Ab Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
AR058807A1 (es) * 2005-09-29 2008-02-27 Astrazeneca Ab 5-(fenilisoxazoletoxi)-triazol-3-il piridinas sustituidas, para el tratamiento de trastornos mediados por el receptor mglur5
TW200821305A (en) * 2006-10-05 2008-05-16 Astrazeneca Ab MGluR5 modulators
PE20090875A1 (es) 2007-10-19 2009-08-08 Astrazeneca Ab Derivados de tetrazol como moduladores de los receptores de glutamato metabotropicos
EP2212316A4 (en) * 2007-10-26 2012-06-27 Astrazeneca Ab DERIVATIVES OF AMINO1,2,4-TRIAZOLES AS MODULATORS OF MGLUR5
WO2010019101A1 (en) * 2008-08-12 2010-02-18 Astrazeneca Ab A crystalline form of 4- (5-{ (ir) -1- [5- (3- chlorophenyl) isoxazol-3-yl] ethoxy } - 4 -methyl- 4h- 1, 2,4- triazol-3-yl) pyridine
CN102176910A (zh) * 2008-08-12 2011-09-07 阿斯利康(瑞典)有限公司 4-(5-{(1r)-1-[5-(3-氯苯基)异噁唑-3-基]乙氧基}-4-甲基-4h-1,2,4-三唑-3-基)吡啶的新晶体形式
CA2751761A1 (en) * 2008-10-22 2010-04-29 House Ear Institute Treatment and/or prevention of inner ear conditions by modulation of a metabotropic glutamate receptor
MX2011005981A (es) * 2008-12-12 2011-06-27 Astrazeneca Ab Nuevo proceso para preparar 4-[4-metil-5-(alquiltio c1-10/aril c5-10-alquilto c1-6)-4h-1,2,4-triazol-3-il]piridinas.
KR20110101164A (ko) * 2008-12-18 2011-09-15 아스트라제네카 아베 1-〔5-(3-클로로-페닐)-이소옥사졸-3-일〕-에타논 및 (ｒ)-1-〔5-(3-클로로-페닐)-이속사졸-3-일〕-에탄올의 신규 제조 방법
EP2379531A1 (en) * 2008-12-18 2011-10-26 AstraZeneca AB Processes for the manufacture of 3-{4-methyl-5- [ (ir) -1- (2- (3-methylphenyl) -2h-tetrazol-5-yl) -ethoxy]-4h- [1,2, 4]triazol-3-yl} -pyridine, 4-methyl-3-methylthio-5- (3- pyridyl)-l,2,4-triazole, and (ir) -1- [2- (3-methylphenyl) -2h- tetrazol-5-yl]ethanol
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
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EP2531490B1 (en) 2010-02-02 2014-10-15 Novartis AG Cyclohexyl amide derivatives as crf receptor antagonists
US8080568B1 (en) * 2010-06-29 2011-12-20 Ewha University - Industry Collaboration Foundation 2-pyridyl substituted imidazoles as therapeutic ALK5 and/or ALK4 inhibitors
UA112418C2 (uk) * 2010-09-07 2016-09-12 Астеллас Фарма Інк. Терапевтичний болезаспокійливий засіб
JP2013544874A (ja) 2010-12-08 2013-12-19 オスロ ユニヴァーシティー ホスピタル エイチエフ Ｗｎｔシグナル伝達経路阻害薬としてのトリアゾール誘導体
WO2012127393A1 (en) 2011-03-18 2012-09-27 Novartis Ag COMBINATIONS OF ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVATORS AND mGluR5 ANTAGONISTS FOR USE IN DOPAMINE INDUCED DYSKINESIA IN PARKINSON'S DISEASE
KR20160120157A (ko) 2015-04-07 2016-10-17 주식회사 메드팩토 암 예방 또는 치료용 약학적 조성물 및 이를 이용한 방법
WO2016163754A1 (en) * 2015-04-07 2016-10-13 Medpacto Inc. Pharmaceutical composition for preventing or treating cancer and method using thereof
KR102027368B1 (ko) * 2018-05-29 2019-10-01 서울대학교산학협력단 통증의 강도를 측정하는 방법
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JP2023501114A (ja) * 2019-11-05 2023-01-18 スーリン、クラース 哺乳動物の過労の予防及び／又は治療に使用するための４－［５－［（ｒａｃ）－１－［５－（３－クロロフェニル）－３－イソキサゾリル］エトキシ］－４－メチル－４ｈ－１，２，４－トリアゾール－３－イル］ピリジン
JP7579337B2 (ja) 2019-11-05 2024-11-07 スーリン、クラース 哺乳動物の過労の予防及び／又は治療に使用するための４－［５－［（ｒａｃ）－１－［５－（３－クロロフェニル）－３－イソキサゾリル］エトキシ］－４－メチル－４ｈ－１，２，４－トリアゾール－３－イル］ピリジン

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AR058807A1 (es) 2008-02-27
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US20080227824A1 (en) 2008-09-18
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US7476684B2 (en) 2009-01-13
CA2623009A1 (en) 2007-04-12
UA92503C2 (ru) 2010-11-10
UY29796A1 (es) 2007-04-30
CN101273037A (zh) 2008-09-24
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US20070270469A1 (en) 2007-11-22
ECSP088283A (es) 2008-04-28

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