JP2009509636A - 変形可能な眼内レンズおよびレンズ系 - Google Patents
変形可能な眼内レンズおよびレンズ系 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1648—Multipart lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
- A61F2/1635—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1637—Correcting aberrations caused by inhomogeneities; correcting intrinsic aberrations, e.g. of the cornea, of the surface of the natural lens, aspheric, cylindrical, toric lenses
- A61F2/164—Aspheric lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1601—Lens body having features to facilitate aqueous fluid flow across the intraocular lens, e.g. for pressure equalization or nutrient delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0018—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in elasticity, stiffness or compressibility
Abstract
Description
今日では、単焦点の眼内レンズが、例えば白内障の形成に起因して失われた視力を回復するために、広く使用されている。この分野におけるより最近の取り組みは、近見視力および遠見視力の両方をもたらすための眼の能力である調節の回復または模擬に注力されている。生まれついての水晶体を除去した後の眼に調節をもたらすための1つの手法は、2つ以上の焦点を同時に生み出す2焦点または多焦点のレンズを使用することである。例えば、特許文献1にてPortneyが教示しているように、表面の種々の部位が異なる焦点距離を有している屈折レンズを生成することができる。あるいは、Cohenが、特許文献2にて、回折位相板を有する2焦点レンズの使用を教示しており、全体としてのレンズが、2つの異なる回折次数に対応する2つの異なる焦点を生み出している。2焦点レンズは、選択された像に対応する焦点を優先するという被験者の脳の能力を利用している。
本発明の実施形態は、広くには、眼に調節をもたらすための装置および方法に向けられており、より具体的には、変形可能な光学素子の表面の少なくとも一部分に、他の光学素子の表面または水晶体嚢の表面に押し合わせられたとき、ならびに/あるいは他の光学素子の表面または水晶体嚢の表面から引き離されたときに、形状の変化または変形を生じさせるための眼科装置(眼内レンズなど)に向けられている。そのような眼科装置を、設計の柔軟性および/または光学収差の軽減をもたらすやり方で、遠見視力および近見視力の両方をもたらすために、容易かつ効果的に変形して形状を変化させるように構成することができる。さらに、本発明の実施形態は、変形可能な光学素子の表面が他の光学素子または水晶体嚢の表面に押し合わせられたとき、あるいは他の光学素子または水晶体嚢の表面から引き離されたときに、2つ以上の焦点をもたらし、少なくとも1つの光学収差を軽減し、かつ/または他の所望の光学的効果をもたらす装置および方法を含んでいる。
Claims (40)
- 光軸を中心にして配置され、固体の材料および変形可能な表面を有している変形可能な光学素子、
光軸を中心にして配置され、固体の材料および剛な表面を有している剛な光学素子、および
眼力に応答して前記変形可能な表面と前記剛な表面とを押し合わせることで、前記変形可能な表面の少なくとも一部分の形状を、該少なくとも一部分の屈折力が少なくとも2ジオプタだけ変化するように変化させるため、前記光学素子の少なくとも一方へと作用可能に接続された支持構造体
を有している眼内レンズ。 - 前記支持構造体が、溝および水晶体嚢の少なくとも一方に配置されるように構成されている請求項1に記載の眼内レンズ。
- 前記剛な光学素子が、眼の後嚢に当接して配置されるように構成されている請求項1に記載の眼内レンズ。
- 前記光学素子の少なくとも一方が、実質的に屈折力を有していない請求項1に記載の眼内レンズ。
- 前記光学素子の少なくとも一方が、2つ以上の屈折力をもたらすように構成されている請求項1に記載の眼内レンズ。
- 前記光学素子の少なくとも一方が、非球面を有している請求項1に記載の眼内レンズ。
- 前記光学素子の少なくとも一方が、回折面を有している請求項1に記載の眼内レンズ。
- 前記変形可能な光学素子が、調節ありのバイアスまたは調節なしのバイアスを有している請求項1に記載の眼内レンズ。
- 前記剛な光学素子が、前記表面が押し合わせられたときに、実質的に固定の形状を維持し、かつ前記変形可能な表面の曲率半径を増加または減少させるように構成されている請求項1に記載の眼内レンズ。
- 前記剛な表面が、前記表面が押し合わせられたときに、前記変形可能な光学素子、当該眼内レンズ、および眼の少なくとも1つの光学収差を軽減するように構成されている請求項1に記載の眼内レンズ。
- 前記変形可能な光学素子が、該変形可能な光学素子が実質的に応力のない状態にあるときに、光軸に沿って或る中央厚さを有しており、眼力が約1〜9グラムの範囲にあるときに、少なくとも1.1の係数にて中央厚さが変化するように構成されている請求項1に記載の眼内レンズ。
- 前記変形可能な光学素子が、該変形可能な光学素子が実質的に応力のない状態にあるときに、光軸に沿って或る中央厚さを有しており、眼力が約1〜9グラムの範囲にあるときに、少なくとも100マイクロメートルだけ中央厚さが変化するように構成されている請求項1に記載の眼内レンズ。
- 前記支持構造体が、1つ以上の支持部を有している請求項1に記載の眼内レンズ。
- 前記支持構造体が、眼の前嚢に従順に当接するように構成された前側セグメントと、眼の後嚢に従順に当接する後ろ側セグメントと、前記前側セグメントおよび前記後ろ側セグメントの間に配置された赤道セグメントとを有する光学素子位置決め部材を有している請求項1に記載の眼内レンズ。
- 前記支持構造体が、眼力に応答して前記赤道セグメントを水晶体嚢の赤道部分に接触した状態に実質的に保つように構成されている請求項14に記載の眼内レンズ。
- 前記剛な光学素子が、実質的に光軸に中心を有する前記前側セグメントの開口に作用可能に接続されている請求項14に記載の眼内レンズ。
- 前記剛な光学素子および前記変形可能な光学素子が、1つ以上の重なり合う開口を有している請求項16に記載の眼内レンズ。
- 前記変形可能な光学素子が、第1の材料で製作され、前記剛な光学素子が、第2の材料で製作され、前記第1の材料の屈折率およびアッベ数の少なくとも一方が、第2の材料と異なっている請求項1に記載の眼内レンズ。
- 前記変形可能な光学素子よりも堅い補強層をさらに有しており、前記変形可能な光学素子が、前記補強層と前記剛な光学素子との間に配置されている請求項1に記載の眼内レンズ。
- 前記変形可能な光学素子が、第1の材料で製作され、前記補強層が、第2の材料で製作され、前記第1の材料の屈折率およびアッベ数の少なくとも一方が、第2の材料と異なっている請求項19に記載の眼内レンズ。
- 前記変形可能な光学素子が、前記変形可能な表面が変形させられるときに該変形可能な光学素子からの材料が膨張できる空間をもたらすための逃げ部をさらに有している請求項1に記載の眼内レンズ。
- 前記逃げ部が、前記変形可能な光学素子を巡る外周の少なくとも一部分を含んでいる請求項21に記載の眼内レンズ。
- 前記逃げ部が、前記変形可能な光学素子の空洞を含んでいる請求項21に記載の眼内レンズ。
- 調節をもたらす方法であって、
光軸を中心にして配置され、固体の材料および変形可能な表面を有している変形可能な光学素子と、
光軸を中心にして配置され、固体の材料および剛な表面を有している剛な光学素子と、
前記光学素子の少なくとも一方に作用可能に接続された支持構造体と、
を有する眼内レンズを用意すること、
前記眼内レンズを被験者の眼へと埋め込むこと、および
眼力に応答して前記変形可能な表面と前記剛な表面とを押し合わせることで、前記変形可能な表面の少なくとも一部分の形状を、該少なくとも一部分の屈折力が少なくとも2ジオプタだけ変化するように変化させるように、前記支持構造体を構成すること
を含んでいる方法。 - 眼力に応答して前記変形可能な表面の曲率半径が増加または減少する一方で、前記剛な表面の曲率半径は実質的に固定に保たれるように、前記眼内レンズを構成すること
をさらに含んでいる請求項24に記載の方法。 - 眼力に応答して前記変形可能な光学素子、前記眼内レンズ、および眼の少なくとも1つの光学収差が軽減されるように、前記眼内レンズを構成すること
をさらに含んでいる請求項24に記載の方法。 - 前記表面が押し合わせられるときに前記変形可能な表面が実質的な球面から非球面へと変化するように、前記眼内レンズを構成すること
をさらに含んでいる請求項24に記載の方法。 - 前記表面が押し合わせられるときに前記変形可能な表面が第1の曲率半径から第1の曲率半径と異なる第2の曲率半径へと変化するように、前記眼内レンズを構成すること
をさらに含んでいる請求項24に記載の方法。 - 光軸、
光軸を中心にして配置され、固体の材料および変形可能な表面を有している変形可能な光学素子、
光軸を中心にして配置され、固体の材料および剛な表面を有している剛な光学素子、および
眼力に応答して前記変形可能な表面と前記剛な表面とを押し合わせることで、前記変形可能な表面の少なくとも一部分の形状を、該少なくとも一部分の屈折力が少なくとも2ジオプタだけ変化するように変化させるための手段
を有している眼内レンズ。 - 光軸を中心にして配置され、固体の材料および変形可能な表面を有している変形可能な光学素子、
光軸を中心にして配置され、固体の材料および剛な表面を有している剛な光学素子、および
眼力が存在しないときに前記変形可能な表面と前記剛な表面とを押し合わせることで、前記変形可能な表面の少なくとも一部分の形状を、該少なくとも一部分の屈折力が少なくとも2ジオプタだけ変化するように変化させるため、前記光学素子の少なくとも一方へと作用可能に接続された支持構造体
を有している眼内レンズ。 - 前記支持構造体が、前記変形可能な表面が前記剛な表面から離れるように移動するときに、眼力に応答して前記少なくとも一部分の形状を変化させるように構成されている請求項30に記載の眼内レンズ。
- 光軸を中心にして配置され、固体の材料および変形可能な表面を有している変形可能な光学素子、
前記変形可能な表面が変形させられるときに前記変形可能な光学素子からの材料が膨張できる空間をもたらすための逃げ部、および
眼力に応答して前記変形可能な表面と眼の水晶体嚢の少なくとも1つの表面とを押し合わせることで、前記変形可能な表面の少なくとも一部分の形状を、該少なくとも一部分の屈折力が少なくとも2ジオプタだけ変化するように変化させるため、前記変形可能な光学素子へと作用可能に接続された支持構造体
を有している眼内レンズ。 - 光軸を中心にして配置され、固体の材料および変形可能な表面を有している変形可能な光学素子、
光軸を中心にして配置され、固体の材料および剛な表面を有している剛な光学素子、および
眼力に応答して前記変形可能な表面と前記剛な表面とを前記変形可能な表面の少なくとも一部分が変形させられて前記剛な表面の形状に一致するように押し合わせる力をもたらすために、前記光学素子の少なくとも一方へと作用可能に接続された支持構造体
を有している眼内レンズ。 - 光軸を中心にして配置され、固体の材料および変形可能な表面を有している変形可能な光学素子、
光軸を中心にして配置され、固体の材料および剛な表面を有している剛な光学素子、および
眼力に応答して前記変形可能な表面と前記剛な表面とを押し合わせることで、前記変形可能な表面の一部分のみの形状を変化させるため、前記光学素子の少なくとも一方へと作用可能に接続された支持構造体
を有している眼内レンズ。 - 前記変形可能な光学素子の前記一部分が、該変形可能な光学素子の中央部分である請求項34に記載の眼内レンズ。
- 前記中央部分が、約2mmよりも大きい直径を有している請求項35に記載の眼内レンズ。
- 前記変形可能な光学素子の前記一部分が、該変形可能な光学素子の外周部分である請求項34に記載の眼内レンズ。
- 前記変形可能な表面が、凹である請求項37に記載の眼内レンズ。
- 前記外周部分が、約4mmよりも小さい内径を有している請求項37に記載の眼内レンズ。
- 前記少なくとも一部分の屈折力が、少なくとも2ジオプタだけ変化する請求項34に記載の眼内レンズ。
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US11/241,586 US9636213B2 (en) | 2005-09-30 | 2005-09-30 | Deformable intraocular lenses and lens systems |
US11/241,586 | 2005-09-30 | ||
PCT/US2006/036242 WO2007040964A1 (en) | 2005-09-30 | 2006-09-18 | Deformable intraocular lenses and lens systems |
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JP2009509636A true JP2009509636A (ja) | 2009-03-12 |
JP4982495B2 JP4982495B2 (ja) | 2012-07-25 |
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JP2008533421A Expired - Fee Related JP4982495B2 (ja) | 2005-09-30 | 2006-09-18 | 変形可能な眼内レンズおよびレンズ系 |
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US (2) | US9636213B2 (ja) |
EP (2) | EP2106770B1 (ja) |
JP (1) | JP4982495B2 (ja) |
AT (2) | ATE447905T1 (ja) |
AU (1) | AU2006297533B2 (ja) |
BR (1) | BRPI0616779A2 (ja) |
CA (1) | CA2624509C (ja) |
DE (2) | DE602006010411D1 (ja) |
WO (1) | WO2007040964A1 (ja) |
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Also Published As
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US20070078515A1 (en) | 2007-04-05 |
DE602006010411D1 (de) | 2009-12-24 |
US20170216021A1 (en) | 2017-08-03 |
US9636213B2 (en) | 2017-05-02 |
EP2106770A1 (en) | 2009-10-07 |
JP4982495B2 (ja) | 2012-07-25 |
EP1928354B1 (en) | 2009-11-11 |
EP1928354A1 (en) | 2008-06-11 |
CA2624509C (en) | 2014-08-05 |
AU2006297533B2 (en) | 2013-03-14 |
BRPI0616779A2 (pt) | 2011-07-05 |
WO2007040964A1 (en) | 2007-04-12 |
CA2624509A1 (en) | 2007-04-12 |
ATE492240T1 (de) | 2011-01-15 |
ATE447905T1 (de) | 2009-11-15 |
AU2006297533A1 (en) | 2007-04-12 |
DE602006019158D1 (de) | 2011-02-03 |
EP2106770B1 (en) | 2010-12-22 |
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