JP2009506141A5 - - Google Patents
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- Publication number
- JP2009506141A5 JP2009506141A5 JP2008527308A JP2008527308A JP2009506141A5 JP 2009506141 A5 JP2009506141 A5 JP 2009506141A5 JP 2008527308 A JP2008527308 A JP 2008527308A JP 2008527308 A JP2008527308 A JP 2008527308A JP 2009506141 A5 JP2009506141 A5 JP 2009506141A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- polymer
- integer
- reactive group
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 229920000642 polymer Polymers 0.000 claims description 10
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims description 6
- AHHWIHXENZJRFG-UHFFFAOYSA-N oxetane Chemical compound C1COC1 AHHWIHXENZJRFG-UHFFFAOYSA-N 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- 125000006239 protecting group Chemical group 0.000 claims 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 125000005543 phthalimide group Chemical group 0.000 claims 3
- 150000001335 aliphatic alkanes Chemical class 0.000 claims 2
- 125000005544 phthalimido group Chemical group 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 239000003054 catalyst Substances 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 125000003566 oxetanyl group Chemical group 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 125000000524 functional group Chemical group 0.000 description 2
- 150000002924 oxiranes Chemical class 0.000 description 2
- GVNVAWHJIKLAGL-UHFFFAOYSA-N 2-(cyclohexen-1-yl)cyclohexan-1-one Chemical compound O=C1CCCCC1C1=CCCCC1 GVNVAWHJIKLAGL-UHFFFAOYSA-N 0.000 description 1
- 101150065749 Churc1 gene Proteins 0.000 description 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 102100038239 Protein Churchill Human genes 0.000 description 1
- 239000002253 acid Chemical group 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 150000001735 carboxylic acids Chemical group 0.000 description 1
- 150000001805 chlorine compounds Chemical class 0.000 description 1
- 150000004292 cyclic ethers Chemical class 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- 150000002513 isocyanates Chemical group 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 150000003573 thiols Chemical group 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPCT/DK2005/000547 | 2005-08-26 | ||
| PCT/DK2005/000547 WO2006021218A1 (en) | 2004-08-27 | 2005-08-26 | Polyether polymer matrix |
| EP06075482 | 2006-03-02 | ||
| EP06075482.7 | 2006-03-02 | ||
| PCT/DK2006/000461 WO2007022780A1 (en) | 2005-08-26 | 2006-08-25 | A method of modifying a macromolecular system |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012062338A Division JP2012180518A (ja) | 2005-08-26 | 2012-03-19 | 高分子システムを変性する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009506141A JP2009506141A (ja) | 2009-02-12 |
| JP2009506141A5 true JP2009506141A5 (https=) | 2012-05-24 |
| JP5021649B2 JP5021649B2 (ja) | 2012-09-12 |
Family
ID=37085311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008527308A Expired - Fee Related JP5021649B2 (ja) | 2005-08-26 | 2006-08-25 | 高分子システムを変性する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7897698B2 (https=) |
| EP (2) | EP2045282B1 (https=) |
| JP (1) | JP5021649B2 (https=) |
| AT (1) | ATE425204T1 (https=) |
| CA (1) | CA2619709C (https=) |
| DE (1) | DE602006005686D1 (https=) |
| ES (1) | ES2323733T3 (https=) |
| WO (1) | WO2007022780A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102635693B1 (ko) | 2015-09-30 | 2024-02-14 | 다우 글로벌 테크놀로지스 엘엘씨 | 알데하이드 모이어티에 아미노 및 폴리메릴 기의 첨가를 통한 작용성 폴리머의 제조 방법 |
| WO2017058910A1 (en) | 2015-09-30 | 2017-04-06 | Dow Global Technologies Llc | Multi- or dual-headed compositions useful for chain shuttling and process to prepare the same |
| EP4435013A3 (en) | 2016-09-30 | 2024-12-25 | Dow Global Technologies LLC | Process for preparing multi- or dual-headed compositions useful for chain shuttling |
| TWI756272B (zh) | 2016-09-30 | 2022-03-01 | 美商陶氏全球科技有限責任公司 | 適用於鏈梭移之封端多頭或雙頭組合物及其製備方法 |
| JP7096236B2 (ja) | 2016-09-30 | 2022-07-05 | ダウ グローバル テクノロジーズ エルエルシー | チェーンシャトリングに有用なマルチヘッドまたはデュアルヘッド組成物、およびそれを調製するプロセス |
| KR102823188B1 (ko) | 2017-12-29 | 2025-06-20 | 다우 글로벌 테크놀로지스 엘엘씨 | 이중 헤드 유기 알루미늄 조성물 |
| SG11202005532YA (en) | 2017-12-29 | 2020-07-29 | Dow Global Technologies Llc | Capped dual-headed organoaluminum compositions |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2631656C2 (de) * | 1976-07-14 | 1983-02-10 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung eines Hydroxysuccinimidoester-Derivats zur Bindung von biologisch aktiven Proteinen aneinander und/oder an flüssige oder feste Trägerstoffe |
| US5483008A (en) * | 1992-02-07 | 1996-01-09 | Research Development Corporation Of Japan | Polyether having heterofunctional groups at both ends, process for the preparation thereof and polymerization initiator therefor |
| JP3465307B2 (ja) * | 1993-08-05 | 2003-11-10 | 日本油脂株式会社 | ポリアルキレンオキシド誘導体および製造方法 |
| JP3465306B2 (ja) * | 1993-08-05 | 2003-11-10 | 日本油脂株式会社 | ポリアルキレンオキシド誘導体および製造方法 |
| JP3508207B2 (ja) * | 1994-05-30 | 2004-03-22 | 日本油脂株式会社 | ポリオキシアルキレン誘導体の製造方法 |
| US5672662A (en) * | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
| GB9713979D0 (en) | 1997-07-03 | 1997-09-10 | Univ Nottingham | Method for attaching peg to macromolecules |
| JP4581248B2 (ja) * | 1998-05-07 | 2010-11-17 | 日油株式会社 | 片末端に保護されていてもよいアミノ基を有するポリオキシエチレン誘導体及びその製造方法 |
| CN1284603C (zh) * | 1999-10-08 | 2006-11-15 | 内科塔治疗亚拉巴马公司 | 杂双官能聚乙二醇衍生物和它们的制备方法 |
| EP1118334A1 (en) * | 2000-01-11 | 2001-07-25 | Aventis Behring Gesellschaft mit beschränkter Haftung | Method for the production of conjugates and uses thereof for the prevention and treatment of allergic reactions and autoimmune diseases |
| WO2001062827A2 (en) | 2000-02-22 | 2001-08-30 | Shearwater Corporation | N-maleimidyl polymer derivatives |
| NO314588B1 (no) * | 2000-09-04 | 2003-04-14 | Bionor Immuno As | HIV-peptider, antigener, vaksinesammensetning, immunoassay- testsett og en fremgangsmåte for å påvise antistoffer indusert av HIV |
| AU2002258913A1 (en) * | 2001-04-23 | 2002-11-05 | Wisconsin Alumni Research Foundation | Bifunctional-modified hydrogels |
| WO2004012773A1 (en) | 2002-07-24 | 2004-02-12 | F. Hoffmann-La Roche Ag | Polyalkylene glycol acid additives |
| EP1581582B2 (en) | 2003-01-06 | 2017-06-07 | Nektar Therapeutics | Thiol-selective water-soluble polmer derivatives |
| JP3770246B2 (ja) * | 2003-04-11 | 2006-04-26 | 日本油脂株式会社 | ポリオキシアルキレン誘導体の製造方法 |
| EP1794209B1 (en) * | 2004-08-27 | 2008-10-08 | Novo Nordisk A/S | Polyether polymer matrix |
-
2006
- 2006-08-25 EP EP09150865A patent/EP2045282B1/en not_active Not-in-force
- 2006-08-25 JP JP2008527308A patent/JP5021649B2/ja not_active Expired - Fee Related
- 2006-08-25 US US11/990,455 patent/US7897698B2/en not_active Expired - Fee Related
- 2006-08-25 CA CA2619709A patent/CA2619709C/en not_active Expired - Fee Related
- 2006-08-25 ES ES06775948T patent/ES2323733T3/es active Active
- 2006-08-25 DE DE602006005686T patent/DE602006005686D1/de active Active
- 2006-08-25 AT AT06775948T patent/ATE425204T1/de not_active IP Right Cessation
- 2006-08-25 EP EP06775948A patent/EP1922355B1/en not_active Not-in-force
- 2006-08-25 WO PCT/DK2006/000461 patent/WO2007022780A1/en not_active Ceased
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