CA2619709C - A method of modifying a macromolecular system - Google Patents

A method of modifying a macromolecular system Download PDF

Info

Publication number
CA2619709C
CA2619709C CA2619709A CA2619709A CA2619709C CA 2619709 C CA2619709 C CA 2619709C CA 2619709 A CA2619709 A CA 2619709A CA 2619709 A CA2619709 A CA 2619709A CA 2619709 C CA2619709 C CA 2619709C
Authority
CA
Canada
Prior art keywords
group
macromolecule
general formula
integer
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2619709A
Other languages
English (en)
French (fr)
Other versions
CA2619709A1 (en
Inventor
Ib Johannsen
Roice Michael
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DK2005/000547 external-priority patent/WO2006021218A1/en
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Priority claimed from PCT/DK2006/000461 external-priority patent/WO2007022780A1/en
Publication of CA2619709A1 publication Critical patent/CA2619709A1/en
Application granted granted Critical
Publication of CA2619709C publication Critical patent/CA2619709C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
    • C08G65/2618—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyethers (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Epoxy Compounds (AREA)
CA2619709A 2005-08-26 2006-08-25 A method of modifying a macromolecular system Expired - Fee Related CA2619709C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/DK2005/000547 WO2006021218A1 (en) 2004-08-27 2005-08-26 Polyether polymer matrix
DKPCT/DK2005/000547 2005-08-26
EP06075482 2006-03-02
EP06075482.7 2006-03-02
PCT/DK2006/000461 WO2007022780A1 (en) 2005-08-26 2006-08-25 A method of modifying a macromolecular system

Publications (2)

Publication Number Publication Date
CA2619709A1 CA2619709A1 (en) 2007-03-01
CA2619709C true CA2619709C (en) 2012-05-01

Family

ID=43825119

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2619709A Expired - Fee Related CA2619709C (en) 2005-08-26 2006-08-25 A method of modifying a macromolecular system

Country Status (6)

Country Link
US (1) US7897698B2 (https=)
EP (1) EP2045282B1 (https=)
JP (2) JP5021649B2 (https=)
AT (1) ATE502971T1 (https=)
CA (1) CA2619709C (https=)
DE (1) DE602006020940D1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5789335B1 (ja) 2014-09-08 2015-10-07 明成化学工業株式会社 分散剤及び分散組成物
WO2017058910A1 (en) 2015-09-30 2017-04-06 Dow Global Technologies Llc Multi- or dual-headed compositions useful for chain shuttling and process to prepare the same
CN108137738B (zh) 2015-09-30 2020-11-06 陶氏环球技术有限责任公司 通过向醛部分加成氨基和聚合物基来制备官能性聚合物的方法
KR102444560B1 (ko) 2016-09-30 2022-09-20 다우 글로벌 테크놀로지스 엘엘씨 체인 셔틀링에 유용한 다중 또는 이중 헤드 구성 요소 및 이를 준비하는 과정
JP7123040B2 (ja) 2016-09-30 2022-08-22 ダウ グローバル テクノロジーズ エルエルシー 連鎖シャトリングに有用な多頭または二頭組成物の調製方法
TWI756272B (zh) 2016-09-30 2022-03-01 美商陶氏全球科技有限責任公司 適用於鏈梭移之封端多頭或雙頭組合物及其製備方法
SG11202005532YA (en) 2017-12-29 2020-07-29 Dow Global Technologies Llc Capped dual-headed organoaluminum compositions
CN111448200A (zh) 2017-12-29 2020-07-24 陶氏环球技术有限责任公司 双头有机铝组合物
CN114058004A (zh) * 2021-11-08 2022-02-18 金湖金凌新材料科技有限公司 一种仿生聚醚拓扑结构的清洗剂及制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631656C2 (de) 1976-07-14 1983-02-10 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung eines Hydroxysuccinimidoester-Derivats zur Bindung von biologisch aktiven Proteinen aneinander und/oder an flüssige oder feste Trägerstoffe
US5483008A (en) * 1992-02-07 1996-01-09 Research Development Corporation Of Japan Polyether having heterofunctional groups at both ends, process for the preparation thereof and polymerization initiator therefor
JP3465307B2 (ja) * 1993-08-05 2003-11-10 日本油脂株式会社 ポリアルキレンオキシド誘導体および製造方法
JP3465306B2 (ja) * 1993-08-05 2003-11-10 日本油脂株式会社 ポリアルキレンオキシド誘導体および製造方法
JP3508207B2 (ja) * 1994-05-30 2004-03-22 日本油脂株式会社 ポリオキシアルキレン誘導体の製造方法
US5672662A (en) 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
GB9713979D0 (en) 1997-07-03 1997-09-10 Univ Nottingham Method for attaching peg to macromolecules
US6388041B1 (en) * 1998-05-07 2002-05-14 Nano Carrier Co Ltd Polyoxyethylene derivatives having optionally protected amino group at one end and process for producing the same
DK1455839T3 (da) 1999-10-08 2013-05-06 Nektar Therapeutics Heterobifunktioneller poly(ethylenglycol)-derivater og fremgangsmåder til fremstilling heraf
EP1118334A1 (en) 2000-01-11 2001-07-25 Aventis Behring Gesellschaft mit beschränkter Haftung Method for the production of conjugates and uses thereof for the prevention and treatment of allergic reactions and autoimmune diseases
US6602498B2 (en) * 2000-02-22 2003-08-05 Shearwater Corporation N-maleimidyl polymer derivatives
NO314588B1 (no) 2000-09-04 2003-04-14 Bionor Immuno As HIV-peptider, antigener, vaksinesammensetning, immunoassay- testsett og en fremgangsmåte for å påvise antistoffer indusert av HIV
EP1423093A4 (en) 2001-04-23 2005-11-30 Wisconsin Alumni Res Found BIFUNCTIONAL MODIFIED HYDROGEL
MXPA05000796A (es) 2002-07-24 2005-04-19 Hoffmann La Roche Aditivos de acidos polialquilenglicolicos.
KR101207247B1 (ko) * 2003-01-06 2012-12-03 넥타르 테라퓨틱스 티올-선택성 수용성 중합체 유도체
JP3770246B2 (ja) 2003-04-11 2006-04-26 日本油脂株式会社 ポリオキシアルキレン誘導体の製造方法
EP1794209B1 (en) * 2004-08-27 2008-10-08 Novo Nordisk A/S Polyether polymer matrix

Also Published As

Publication number Publication date
DE602006020940D1 (de) 2011-05-05
ATE502971T1 (de) 2011-04-15
JP2009506141A (ja) 2009-02-12
EP2045282B1 (en) 2011-03-23
JP5021649B2 (ja) 2012-09-12
US20090209710A1 (en) 2009-08-20
CA2619709A1 (en) 2007-03-01
EP2045282A1 (en) 2009-04-08
US7897698B2 (en) 2011-03-01
JP2012180518A (ja) 2012-09-20

Similar Documents

Publication Publication Date Title
JP2012180518A (ja) 高分子システムを変性する方法
KR100512483B1 (ko) 신규한 폴리에틸렌글리콜-말레이미드 유도체의 합성방법
KR100948532B1 (ko) 분지형 중합체 및 그의 공액체
US7868132B2 (en) Method for preparing multi-arm poly (ethylene glycol) amines
EP0546055B1 (en) Polyethylene glycol derivatives for solid-phase applications
KR101793704B1 (ko) 막 향상된 고분자 합성
CN104245791B (zh) 多臂聚乙二醇衍生物、其中间体以及它们的制造方法
WO2015048728A1 (en) Methods for post-fabrication functionalization of poly(ester ureas)
US5545698A (en) Polyethylene glycol derivatives for solid-phase applications
EP2554565B1 (en) Multifunctional polyoxyalkylene compound, method for producing same and intermediate of same
JP5612467B2 (ja) Ｆｍｏｃをベースとした加水分解性リンカーの調製方法
KR20080056267A (ko) 보호된 아민 염을 이용하는 말단 아민기를 갖는 중합체의제조방법
ES2363122T3 (es) Método para modificar un sistema macromolecular.
EP1922355B1 (en) A method of modifying a macromolecular system
KR102580547B1 (ko) 멀티 암형 폴리에틸렌 글리콜 유도체의 제조 방법
WO2011056799A1 (en) Methods for preparing polyethylene glycol maleimide using n-(2-hydroxyethyl) maleimide as a starting material
Siyad et al. Synthetic evaluation of disulphide-bonded sarafotoxin on a poly (oxy ether) grafted dendrimeric poly (alkyl amine) support for polymer assisted organic synthesis

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20140826