JP2009504771A5 - - Google Patents

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Publication number
JP2009504771A5
JP2009504771A5 JP2008527148A JP2008527148A JP2009504771A5 JP 2009504771 A5 JP2009504771 A5 JP 2009504771A5 JP 2008527148 A JP2008527148 A JP 2008527148A JP 2008527148 A JP2008527148 A JP 2008527148A JP 2009504771 A5 JP2009504771 A5 JP 2009504771A5
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JP
Japan
Prior art keywords
aliphatic
ring
compound according
cancer
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008527148A
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English (en)
Japanese (ja)
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JP2009504771A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/032191 external-priority patent/WO2007022384A2/en
Publication of JP2009504771A publication Critical patent/JP2009504771A/ja
Publication of JP2009504771A5 publication Critical patent/JP2009504771A5/ja
Pending legal-status Critical Current

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JP2008527148A 2005-08-18 2006-08-17 ピラジンキナーゼ阻害剤 Pending JP2009504771A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70954105P 2005-08-18 2005-08-18
US70976005P 2005-08-19 2005-08-19
US72059605P 2005-09-26 2005-09-26
PCT/US2006/032191 WO2007022384A2 (en) 2005-08-18 2006-08-17 Pyrazine kinase inhibitors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012234358A Division JP2013014632A (ja) 2005-08-18 2012-10-24 ピラジンキナーゼ阻害剤

Publications (2)

Publication Number Publication Date
JP2009504771A JP2009504771A (ja) 2009-02-05
JP2009504771A5 true JP2009504771A5 (enExample) 2009-10-08

Family

ID=37680628

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008527148A Pending JP2009504771A (ja) 2005-08-18 2006-08-17 ピラジンキナーゼ阻害剤
JP2012234358A Pending JP2013014632A (ja) 2005-08-18 2012-10-24 ピラジンキナーゼ阻害剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012234358A Pending JP2013014632A (ja) 2005-08-18 2012-10-24 ピラジンキナーゼ阻害剤

Country Status (7)

Country Link
US (2) US7737151B2 (enExample)
EP (1) EP1917259B1 (enExample)
JP (2) JP2009504771A (enExample)
AT (1) ATE542814T1 (enExample)
AU (1) AU2006279376B2 (enExample)
CA (1) CA2619517A1 (enExample)
WO (1) WO2007022384A2 (enExample)

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WO2004072029A2 (en) 2003-02-06 2004-08-26 Vertex Pharmaceuticals Incorporated Pyrazolopyridazines useful as inhibitors of protein kinases
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TW200734327A (en) 2005-11-03 2007-09-16 Vertex Pharma Aminopyrimidines useful as kinase inhibitors
WO2008057940A1 (en) 2006-11-02 2008-05-15 Vertex Pharmaceuticals Incorporated Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases
WO2008077086A1 (en) 2006-12-19 2008-06-26 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as inhibitors of protein kinases
WO2008112642A1 (en) 2007-03-09 2008-09-18 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as inhibitors of protein kinases
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EP2134709A1 (en) 2007-03-09 2009-12-23 Vertex Pharmaceuticals, Inc. Aminopyridines useful as inhibitors of protein kinases
JP2010523700A (ja) 2007-04-13 2010-07-15 バーテックス ファーマシューティカルズ インコーポレイテッド キナーゼインヒビターとして有用なアミノピリミジン
CN101801959A (zh) 2007-05-02 2010-08-11 沃泰克斯药物股份有限公司 可用作激酶抑制剂的氨基嘧啶类化合物
CN101679378A (zh) 2007-05-02 2010-03-24 沃泰克斯药物股份有限公司 用作激酶抑制剂的噻唑和吡唑
JP2010529193A (ja) * 2007-06-11 2010-08-26 ミイカナ セラピューティクス インコーポレイテッド 置換ピラゾール化合物
AR067762A1 (es) * 2007-07-31 2009-10-21 Vertex Pharma Proceso para preparar 5-fluoro-1h-pirazolo (3,4-b) piridin-3-amina y derivados de la misma
ES2393824T3 (es) * 2007-09-21 2012-12-28 Array Biopharma, Inc. Derivados de piridin-2-il-amino-1,2,4-tiadiazol como activadores de glucoquinasa para el tratamiento de diabetes mellitus
TWI485146B (zh) * 2012-02-29 2015-05-21 Taiho Pharmaceutical Co Ltd Novel piperidine compounds or salts thereof
AU2013205306B2 (en) 2012-03-16 2015-09-17 Axikin Pharmaceuticals, Inc. 3,5-diaminopyrazole kinase inhibitors
NZ631142A (en) 2013-09-18 2016-03-31 Axikin Pharmaceuticals Inc Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
CN107250116B (zh) 2014-12-23 2020-10-27 艾士盟医疗公司 3,5-二氨基吡唑激酶抑制剂

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