JP2010510216A5 - - Google Patents
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- Publication number
- JP2010510216A5 JP2010510216A5 JP2009537209A JP2009537209A JP2010510216A5 JP 2010510216 A5 JP2010510216 A5 JP 2010510216A5 JP 2009537209 A JP2009537209 A JP 2009537209A JP 2009537209 A JP2009537209 A JP 2009537209A JP 2010510216 A5 JP2010510216 A5 JP 2010510216A5
- Authority
- JP
- Japan
- Prior art keywords
- ring
- compound according
- independently
- groups
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 C*C=C(CC1CC(C)(C)C(C(C)C)C(CC(C)=C)C1)*C Chemical compound C*C=C(CC1CC(C)(C)C(C(C)C)C(CC(C)=C)C1)*C 0.000 description 7
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85911306P | 2006-11-15 | 2006-11-15 | |
| US98414907P | 2007-10-31 | 2007-10-31 | |
| PCT/US2007/023999 WO2008060597A2 (en) | 2006-11-15 | 2007-11-15 | Compounds useful as protein kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010510216A JP2010510216A (ja) | 2010-04-02 |
| JP2010510216A5 true JP2010510216A5 (enExample) | 2011-12-15 |
Family
ID=39402262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009537209A Pending JP2010510216A (ja) | 2006-11-15 | 2007-11-15 | プロテインキナーゼのインヒビターとして有用な化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US7838517B2 (enExample) |
| EP (1) | EP2094712B1 (enExample) |
| JP (1) | JP2010510216A (enExample) |
| AT (1) | ATE528309T1 (enExample) |
| AU (1) | AU2007319786A1 (enExample) |
| CA (1) | CA2669886A1 (enExample) |
| ES (1) | ES2372320T3 (enExample) |
| MX (1) | MX2009005231A (enExample) |
| NZ (1) | NZ576950A (enExample) |
| WO (1) | WO2008060597A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0620059D0 (en) * | 2006-10-10 | 2006-11-22 | Ucb Sa | Therapeutic agents |
| JP2010510216A (ja) | 2006-11-15 | 2010-04-02 | バーテックス ファーマシューティカルズ インコーポレイテッド | プロテインキナーゼのインヒビターとして有用な化合物 |
| AU2010332811B2 (en) * | 2009-12-18 | 2014-07-24 | Janssen Pharmaceutica Nv | Bicyclic thiazoles as allosteric modulators of mGluR5 receptors |
| WO2011073347A1 (en) | 2009-12-18 | 2011-06-23 | Janssen Pharmaceutica Nv | Bicyclic thiazoles as allosteric modulators of mglur5 receptors |
| WO2012000103A1 (en) | 2010-07-02 | 2012-01-05 | University Health Network | Methods of targeting pten mutant diseases and compositions therefor |
| CN110167944B (zh) * | 2016-12-12 | 2024-08-23 | 联合疗法公司 | 取代的吡唑并氮杂䓬-4-酮类及其作为磷酸二酯酶抑制剂的用途 |
| ES2875128T3 (es) | 2016-12-12 | 2021-11-08 | Union Therapeutics As | Pirazoloazepin-8-onas sustituidas y su uso como inhibidores de la fosfodiesterasa |
| EP3551634B1 (en) | 2016-12-12 | 2021-03-31 | Leo Pharma A/S | Substituted pyrazoloazepin-8-ones and their use as phosphodiesterase inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH632755A5 (de) | 1976-04-10 | 1982-10-29 | Basf Ag | Verfahren zur herstellung von thiophenverbindungen. |
| US5206240A (en) | 1989-12-08 | 1993-04-27 | Merck & Co., Inc. | Nitrogen-containing spirocycles |
| KR930703327A (ko) | 1991-12-26 | 1993-11-29 | 고야 다다시 | 축합형 티오펜 화합물 및 그의 의약용도 |
| AU2003297431A1 (en) * | 2002-12-20 | 2004-07-22 | Pharmacia Corporation | Mitogen activated protein kinase-activated protein kinase-2 inhibiting compounds |
| AU2005208938A1 (en) | 2004-01-29 | 2005-08-11 | Elixir Pharmaceuticals, Inc | Anti-viral therapeutics |
| GB0508471D0 (en) * | 2005-04-26 | 2005-06-01 | Celltech R&D Ltd | Therapeutic agents |
| JP2010510216A (ja) | 2006-11-15 | 2010-04-02 | バーテックス ファーマシューティカルズ インコーポレイテッド | プロテインキナーゼのインヒビターとして有用な化合物 |
-
2007
- 2007-11-15 JP JP2009537209A patent/JP2010510216A/ja active Pending
- 2007-11-15 MX MX2009005231A patent/MX2009005231A/es active IP Right Grant
- 2007-11-15 NZ NZ576950A patent/NZ576950A/en not_active IP Right Cessation
- 2007-11-15 EP EP07867462A patent/EP2094712B1/en not_active Not-in-force
- 2007-11-15 AT AT07867462T patent/ATE528309T1/de not_active IP Right Cessation
- 2007-11-15 WO PCT/US2007/023999 patent/WO2008060597A2/en not_active Ceased
- 2007-11-15 CA CA002669886A patent/CA2669886A1/en not_active Abandoned
- 2007-11-15 ES ES07867462T patent/ES2372320T3/es active Active
- 2007-11-15 AU AU2007319786A patent/AU2007319786A1/en not_active Abandoned
-
2009
- 2009-05-15 US US12/466,420 patent/US7838517B2/en not_active Expired - Fee Related
-
2010
- 2010-10-13 US US12/903,390 patent/US8399458B2/en not_active Expired - Fee Related
-
2013
- 2013-02-13 US US13/765,864 patent/US20130267498A1/en not_active Abandoned
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