|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
|
US7179617B2
(en)
*
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
|
US7157277B2
(en)
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
|
US8008252B2
(en)
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
|
DE60336555D1
(de)
|
2002-06-21 |
2011-05-12 |
Novo Nordisk Healthcare Ag |
Pegylierte glykoformen von faktor vii
|
|
US8003117B2
(en)
*
|
2002-11-20 |
2011-08-23 |
Nof Corporation |
Polyalkylene glycol derivative and modified bio-related substance
|
|
US8828373B2
(en)
*
|
2002-11-20 |
2014-09-09 |
Nof Corporation |
Polyalkylene glycol derivative and modified bio-related substance
|
|
JP4412461B2
(ja)
*
|
2002-11-20 |
2010-02-10 |
日油株式会社 |
修飾された生体関連物質、その製造方法および中間体
|
|
RS20050501A
(sr)
*
|
2002-12-26 |
2007-08-03 |
Mountain View Pharmaceuticals Inc., |
Polimerni konjugati citokina,hemokina,faktora rasta, polipeptidnih hormona i njihovih antagonista sa očuvanom aktivnošću vezivanja receptora
|
|
GEP20084486B
(en)
|
2002-12-26 |
2008-09-25 |
Mountain View Pharmaceuticals |
Polymer conjugates of interferon-beta with enhanced biological potency
|
|
US7432331B2
(en)
|
2002-12-31 |
2008-10-07 |
Nektar Therapeutics Al, Corporation |
Hydrolytically stable maleimide-terminated polymers
|
|
AU2004221824B2
(en)
|
2003-03-14 |
2009-08-27 |
Ratiopharm Gmbh |
Branched water-soluble polymers and their conjugates
|
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
|
CA2522345A1
(en)
|
2003-04-09 |
2004-11-18 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
|
US7932364B2
(en)
|
2003-05-09 |
2011-04-26 |
Novo Nordisk A/S |
Compositions and methods for the preparation of human growth hormone glycosylation mutants
|
|
WO2005012484A2
(en)
|
2003-07-25 |
2005-02-10 |
Neose Technologies, Inc. |
Antibody-toxin conjugates
|
|
NZ592039A
(en)
*
|
2003-08-27 |
2013-03-28 |
Ophthotech Corp |
Combination therapy for the treatment of ocular neovascular disorders
|
|
US8633157B2
(en)
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
|
US20060040856A1
(en)
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
|
NZ548123A
(en)
|
2004-01-08 |
2010-05-28 |
Novo Nordisk As |
O-linked glycosylation of peptides
|
|
WO2006010143A2
(en)
|
2004-07-13 |
2006-01-26 |
Neose Technologies, Inc. |
Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
|
|
AU2005278903A1
(en)
*
|
2004-08-31 |
2006-03-09 |
Pharmacia & Upjohn Company Llc |
Glycerol branched polyethylene glycol human growth hormone conjugates, process for their preparation, and methods of use thereof
|
|
WO2006031811A2
(en)
|
2004-09-10 |
2006-03-23 |
Neose Technologies, Inc. |
Glycopegylated interferon alpha
|
|
EP1814573B1
(en)
|
2004-10-29 |
2016-03-09 |
ratiopharm GmbH |
Remodeling and glycopegylation of fibroblast growth factor (fgf)
|
|
DK2371856T3
(en)
|
2004-11-12 |
2022-08-08 |
Bayer Healthcare Llc |
Site-directed modifikation af FVIII
|
|
CA2593682C
(en)
|
2005-01-10 |
2016-03-22 |
Neose Technologies, Inc. |
Glycopegylated granulocyte colony stimulating factor
|
|
JP4877225B2
(ja)
*
|
2005-02-18 |
2012-02-15 |
日油株式会社 |
ポリオキシアルキレン誘導体
|
|
US9187546B2
(en)
|
2005-04-08 |
2015-11-17 |
Novo Nordisk A/S |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
|
US20080255026A1
(en)
*
|
2005-05-25 |
2008-10-16 |
Glycopegylated Factor 1X |
Glycopegylated Factor Ix
|
|
KR100735784B1
(ko)
*
|
2005-07-20 |
2007-07-06 |
재단법인 목암생명공학연구소 |
인간 과립구콜로니자극인자 변이체 및 이의 화학적 접합물
|
|
US20070105755A1
(en)
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
|
US20090048440A1
(en)
|
2005-11-03 |
2009-02-19 |
Neose Technologies, Inc. |
Nucleotide Sugar Purification Using Membranes
|
|
EP1787660A1
(en)
*
|
2005-11-22 |
2007-05-23 |
GBF Gesellschaft für Biotechnologische Forschung mbH |
New adjuvants on the basis of bisacyloxypropylcysteine conjugates and their uses in pharmaceutical compositions
|
|
JP2009536963A
(ja)
*
|
2006-05-12 |
2009-10-22 |
ドン・ア・ファーム・カンパニー・リミテッド |
ポリエチレングリコール−インターフェロンα結合体
|
|
CN101516388B
(zh)
|
2006-07-21 |
2012-10-31 |
诺和诺德公司 |
通过o-联糖基化序列的肽的糖基化
|
|
JP5277599B2
(ja)
*
|
2006-09-29 |
2013-08-28 |
日油株式会社 |
生分解性ポリオキシアルキレン誘導体の製造方法
|
|
US8969532B2
(en)
|
2006-10-03 |
2015-03-03 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
|
|
WO2008060780A2
(en)
*
|
2006-10-04 |
2008-05-22 |
Novo Nordisk A/S |
Glycerol linked pegylated sugars and glycopeptides
|
|
KR101079993B1
(ko)
*
|
2006-11-17 |
2011-11-04 |
동아제약주식회사 |
폴리에틸렌글리콜 과립구 콜로니 자극인자 접합체
|
|
JP5515224B2
(ja)
|
2007-02-28 |
2014-06-11 |
日油株式会社 |
多分岐鎖ポリオキシアルキレン誘導体
|
|
EP2144923B1
(en)
|
2007-04-03 |
2013-02-13 |
BioGeneriX AG |
Methods of treatment using glycopegylated g-csf
|
|
WO2008154639A2
(en)
|
2007-06-12 |
2008-12-18 |
Neose Technologies, Inc. |
Improved process for the production of nucleotide sugars
|
|
US8207112B2
(en)
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
|
US20130189239A1
(en)
|
2008-02-27 |
2013-07-25 |
Novo Nordisk A/S |
Conjugated Factor VIII Molecules
|
|
US20090246430A1
(en)
|
2008-03-28 |
2009-10-01 |
The Coca-Cola Company |
Bio-based polyethylene terephthalate polymer and method of making same
|
|
CN105254858A
(zh)
|
2009-03-03 |
2016-01-20 |
可口可乐公司 |
生物基聚对苯二甲酸乙二酯包装及制备其的方法
|
|
JP5418360B2
(ja)
*
|
2009-03-27 |
2014-02-19 |
日油株式会社 |
ポリオキシアルキレン誘導体の製造方法
|
|
JP5589503B2
(ja)
*
|
2009-03-31 |
2014-09-17 |
日油株式会社 |
多分岐鎖ポリオキシアルキレン化合物、その製造方法および中間体
|
|
JP5569787B2
(ja)
*
|
2009-03-31 |
2014-08-13 |
日油株式会社 |
高分子量ポリエチレングリコール化合物の精製方法
|
|
US8816099B2
(en)
*
|
2010-03-31 |
2014-08-26 |
Nof Corporation |
Polyfunctional polyoxyalkylene compound, and producing method and intermediate thereof
|
|
EP2569331A1
(en)
|
2010-05-10 |
2013-03-20 |
Perseid Therapeutics LLC |
Polypeptide inhibitors of vla4
|
|
JP2013533217A
(ja)
|
2010-05-17 |
2013-08-22 |
セビックス・インコーポレイテッド |
Ｐｅｇ化ｃ−ペプチド
|
|
US10040761B2
(en)
|
2010-06-25 |
2018-08-07 |
Nof Corporation |
Branched hetero polyethylene glycol and intermediate
|
|
CA2803446C
(en)
|
2010-07-02 |
2019-06-04 |
University Health Network |
Use of plk4 antagonists for treating pten mutant diseases
|
|
JP5949037B2
(ja)
|
2011-03-30 |
2016-07-06 |
日油株式会社 |
末端に複数の水酸基を有するポリオキシエチレン誘導体
|
|
WO2014157150A1
(ja)
|
2013-03-25 |
2014-10-02 |
日油株式会社 |
ベンジリデンアセタールリンカーを有する親水性ポリマー誘導体
|
|
EP2980115B1
(en)
|
2013-03-27 |
2019-03-06 |
NOF Corporation |
Purification method for polyethylene glycol having a single amino group
|
|
SI4374873T1
(sl)
|
2013-07-12 |
2026-01-30 |
Astellas Us Llc |
Sredstvo za uporabo pri zdravljenju ali preprečevanju oftalmoloških stanj
|
|
CN103881084B
(zh)
*
|
2014-03-14 |
2016-09-28 |
厦门赛诺邦格生物科技股份有限公司 |
一种支化聚乙二醇的磷脂类衍生物及其组成的脂质膜结构体
|
|
WO2017043653A1
(ja)
*
|
2015-09-11 |
2017-03-16 |
国立大学法人 東京大学 |
タンパク質を安定化するための化合物
|
|
JP6860827B2
(ja)
*
|
2016-04-28 |
2021-04-21 |
日油株式会社 |
分岐型ポリオキシエチレン化合物およびコンタクトレンズ
|
|
US11613607B2
(en)
|
2016-10-07 |
2023-03-28 |
Tokyo Institute Of Technology |
Branched type hetero monodispersed polyethylene glycol, production method thereof, and conjugate thereof
|
|
JP6935059B2
(ja)
|
2017-03-30 |
2021-09-15 |
日油株式会社 |
カルボキシル基を一つ有するポリエチレングリコールの精製方法
|
|
CA3094055A1
(en)
|
2018-03-20 |
2019-09-26 |
Nof Corporation |
Branched monodispersed polyethylene glycol, intermediate and methods for producing same
|
|
US12441776B2
(en)
|
2018-11-30 |
2025-10-14 |
Eirgen Pharma Ltd. |
Oxyntomodulin peptide analog formulations
|
|
CA3164940A1
(en)
|
2019-12-27 |
2021-07-01 |
Nof Corporation |
Method for purifying branched polyethylene glycol
|
|
KR102860222B1
(ko)
|
2019-12-27 |
2025-09-16 |
니치유 가부시키가이샤 |
폴리에틸렌 글리콜 화합물의 정제 방법
|
|
US20250197564A1
(en)
|
2022-03-09 |
2025-06-19 |
Nof Corporation |
Method for producing polyoxyethylene derivative, method for quantitating polyoxyethylene compound, and labeling reagent for analysis use
|
|
US20250179245A1
(en)
*
|
2022-03-17 |
2025-06-05 |
Nof Corporation |
Method for producing polyethylene glycol derivative
|
|
EP4786520A1
(en)
|
2023-09-27 |
2026-08-05 |
NOF Corporation |
Method for producing polyethylene glycol derivative having carboxyl group at terminal
|
|
WO2025070456A1
(ja)
|
2023-09-29 |
2025-04-03 |
日油株式会社 |
高純度の分岐鎖状ポリエチレングリコール化合物の製造方法
|