JP2006505634A5 - - Google Patents

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Publication number
JP2006505634A5
JP2006505634A5 JP2004528078A JP2004528078A JP2006505634A5 JP 2006505634 A5 JP2006505634 A5 JP 2006505634A5 JP 2004528078 A JP2004528078 A JP 2004528078A JP 2004528078 A JP2004528078 A JP 2004528078A JP 2006505634 A5 JP2006505634 A5 JP 2006505634A5
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JP
Japan
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alkyl
substituted
independently
independently selected
components
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JP2004528078A
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English (en)
Japanese (ja)
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JP2006505634A (ja
JP4308764B2 (ja
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Priority claimed from US10/218,167 external-priority patent/US7122189B2/en
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Publication of JP2006505634A publication Critical patent/JP2006505634A/ja
Publication of JP2006505634A5 publication Critical patent/JP2006505634A5/ja
Application granted granted Critical
Publication of JP4308764B2 publication Critical patent/JP4308764B2/ja
Anticipated expiration legal-status Critical
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JP2004528078A 2002-08-13 2003-08-13 脂肪族生物分解性リンカーに基づく放出可能な高分子コンジュゲート Expired - Fee Related JP4308764B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/218,167 US7122189B2 (en) 2002-08-13 2002-08-13 Releasable polymeric conjugates based on aliphatic biodegradable linkers
PCT/US2003/025252 WO2004014424A1 (en) 2002-08-13 2003-08-13 Releasable polymeric conjugates based on aliphatic biodegradable linkers

Publications (3)

Publication Number Publication Date
JP2006505634A JP2006505634A (ja) 2006-02-16
JP2006505634A5 true JP2006505634A5 (enExample) 2006-07-20
JP4308764B2 JP4308764B2 (ja) 2009-08-05

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Family Applications (1)

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JP2004528078A Expired - Fee Related JP4308764B2 (ja) 2002-08-13 2003-08-13 脂肪族生物分解性リンカーに基づく放出可能な高分子コンジュゲート

Country Status (9)

Country Link
US (2) US7122189B2 (enExample)
EP (2) EP1534334B1 (enExample)
JP (1) JP4308764B2 (enExample)
KR (1) KR20050047096A (enExample)
AU (1) AU2003262622B2 (enExample)
CA (1) CA2493329C (enExample)
MX (1) MXPA05001716A (enExample)
NZ (1) NZ537956A (enExample)
WO (1) WO2004014424A1 (enExample)

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CN103897176B (zh) * 2012-12-24 2018-08-17 张雅珍 蒽环类抗生素偶联非线性多嵌段共聚物及其制备方法和应用
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CN103910870B (zh) * 2012-12-28 2018-08-17 张雅珍 蒽环类抗生素偶联非线性多嵌段共聚物及其制备方法和应用
CN103910871A (zh) * 2012-12-28 2014-07-09 张雅珍 蒽环类抗生素偶联非线性多嵌段共聚物及其制备方法和应用
CN103910866B (zh) * 2012-12-31 2018-08-17 张雅珍 含有蒽环类抗生素结构的新化合物以及制备方法和用途
CN110143999B (zh) 2013-03-15 2023-12-05 酵活英属哥伦比亚省公司 具细胞毒性和抗有丝分裂的化合物以及其使用方法
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JP6378837B2 (ja) 2015-04-24 2018-08-22 デューク・ユニヴァーシティ イメージング剤として有用なビスホスホネート又はピロホスフェートを有する金属錯体
US10835578B2 (en) 2016-01-08 2020-11-17 Ascendis Pharma Growth Disorders A/S CNP prodrugs with large carrier moieties
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WO2017118698A1 (en) 2016-01-08 2017-07-13 Ascendis Pharma Growth Disorders A/S Cnp prodrugs with carrier attachment at the ring moiety
CN108472380B (zh) 2016-01-08 2022-03-01 阿森迪斯药物生长障碍股份有限公司 具有增加的nep稳定性的控制释放cnp激动剂
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EP4223309A1 (en) 2016-09-29 2023-08-09 Ascendis Pharma Growth Disorders A/S Combination therapy with controlled-release cnp agonists
US12453778B2 (en) 2016-09-29 2025-10-28 Ascendis Pharma Bone Diseases A/S Incremental dose finding in controlled-release PTH compounds
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