JP2005528380A5 - - Google Patents

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Publication number
JP2005528380A5
JP2005528380A5 JP2003582125A JP2003582125A JP2005528380A5 JP 2005528380 A5 JP2005528380 A5 JP 2005528380A5 JP 2003582125 A JP2003582125 A JP 2003582125A JP 2003582125 A JP2003582125 A JP 2003582125A JP 2005528380 A5 JP2005528380 A5 JP 2005528380A5
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JP
Japan
Prior art keywords
substituted
alkyl
group
compound
heteroalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003582125A
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English (en)
Japanese (ja)
Other versions
JP4527404B2 (ja
JP2005528380A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/009875 external-priority patent/WO2003084926A2/en
Publication of JP2005528380A publication Critical patent/JP2005528380A/ja
Publication of JP2005528380A5 publication Critical patent/JP2005528380A5/ja
Application granted granted Critical
Publication of JP4527404B2 publication Critical patent/JP4527404B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2003582125A 2002-04-04 2003-03-31 インドールのポリマー性アシル誘導体 Expired - Fee Related JP4527404B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36973202P 2002-04-04 2002-04-04
PCT/US2003/009875 WO2003084926A2 (en) 2002-04-04 2003-03-31 Polymeric acyl derivatives of indoles

Publications (3)

Publication Number Publication Date
JP2005528380A JP2005528380A (ja) 2005-09-22
JP2005528380A5 true JP2005528380A5 (enExample) 2006-03-02
JP4527404B2 JP4527404B2 (ja) 2010-08-18

Family

ID=28791989

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003582125A Expired - Fee Related JP4527404B2 (ja) 2002-04-04 2003-03-31 インドールのポリマー性アシル誘導体

Country Status (6)

Country Link
US (1) US7393953B2 (enExample)
EP (1) EP1494757A2 (enExample)
JP (1) JP4527404B2 (enExample)
AU (1) AU2003226166A1 (enExample)
CA (1) CA2479810A1 (enExample)
WO (1) WO2003084926A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1757607A1 (en) 2005-08-24 2007-02-28 Molisa GmbH N5-substituted benzo¬2,3|azepino¬4,5-b|indol-6-ones for treating tropical diseases
JP2010521465A (ja) * 2007-03-12 2010-06-24 ネクター セラピューティックス 複合体のデノボ合成
WO2008112287A1 (en) * 2007-03-12 2008-09-18 Nektar Therapeutics Oligomer-beta blocker conjugates
WO2009032286A2 (en) * 2007-09-06 2009-03-12 Nektar Therapeutics Al, Corporation Oligomer-calcium channel blocker conjugates
AU2010277559B2 (en) 2009-07-31 2016-08-11 Sanofi-Aventis Deutschland Gmbh Prodrugs comprising an insulin linker conjugate
PT2459171T (pt) 2009-07-31 2017-08-16 Sanofi Aventis Deutschland Composição de insulina de atuação longa
ES2833035T3 (es) 2009-07-31 2021-06-14 Ascendis Pharma As Hidrogeles biodegradables insolubles en agua a base de polietilenglicol
US20120289571A1 (en) * 2009-12-31 2012-11-15 Enzon Pharmaceuticals, Inc. Polymeric conjugates of aromatic amine containing compounds including releasable urea linker
EP2438930A1 (en) 2010-09-17 2012-04-11 Sanofi-Aventis Deutschland GmbH Prodrugs comprising an exendin linker conjugate
WO2013024048A1 (en) 2011-08-12 2013-02-21 Ascendis Pharma A/S Polymeric hyperbranched carrier-linked prodrugs
US20140323402A1 (en) 2011-08-12 2014-10-30 Ascendis Phama A/S Protein Carrier-Linked Prodrugs
EP2741779A1 (en) 2011-08-12 2014-06-18 Ascendis Pharma A/S High-loading water-soluble carrier-linked prodrugs
MY171920A (en) 2011-10-12 2019-11-07 Ascendis Pharma Ophthalmology Div A/S Prevention and treatment of ocular conditions
EP2906245B1 (en) 2012-10-11 2021-01-13 Ascendis Pharma A/S Diagnosis, prevention and treatment of diseases of the joint

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840900A (en) * 1993-10-20 1998-11-24 Enzon, Inc. High molecular weight polymer-based prodrugs
DE19636889A1 (de) * 1996-09-11 1998-03-12 Felix Dr Kratz Antineoplastisch wirkende Transferrin- und Albuminkonjugate zytostatischer Verbindungen aus der Gruppe der Anthrazykline, Alkylantien, Antimetabolite und Cisplatin-Analoga und diese enthaltende Arzneimittel
US6251382B1 (en) * 1998-04-17 2001-06-26 Enzon, Inc. Biodegradable high molecular weight polymeric linkers and their conjugates
US6153655A (en) * 1998-04-17 2000-11-28 Enzon, Inc. Terminally-branched polymeric linkers and polymeric conjugates containing the same
CA2335115C (en) 1998-06-16 2009-01-27 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Fused azepinone cyclin dependent kinase inhibitors
FR2804959B1 (fr) * 2000-02-15 2006-04-28 Centre Nat Rech Scient Utilisation de derives de paullones pour la fabrication de medicaments

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