JP2008538282A - 装置および循環腫瘍細胞および他の粒子の濃縮および変更のための方法 - Google Patents
装置および循環腫瘍細胞および他の粒子の濃縮および変更のための方法 Download PDFInfo
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- JP2008538282A JP2008538282A JP2008505508A JP2008505508A JP2008538282A JP 2008538282 A JP2008538282 A JP 2008538282A JP 2008505508 A JP2008505508 A JP 2008505508A JP 2008505508 A JP2008505508 A JP 2008505508A JP 2008538282 A JP2008538282 A JP 2008538282A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G01N33/483—Physical analysis of biological material
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- G—PHYSICS
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
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- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
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- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1029—Particle size
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- G—PHYSICS
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- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66841505P | 2005-04-05 | 2005-04-05 | |
| US70383305P | 2005-07-29 | 2005-07-29 | |
| US11/323,946 US20070026415A1 (en) | 2005-07-29 | 2005-12-29 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11/324,041 US20070026418A1 (en) | 2005-07-29 | 2005-12-29 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11/323,962 US20070026417A1 (en) | 2005-07-29 | 2005-12-29 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11/323,945 US20070026414A1 (en) | 2005-07-29 | 2005-12-29 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11/322,790 US20070026413A1 (en) | 2005-07-29 | 2005-12-29 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| PCT/US2006/012778 WO2006108087A2 (en) | 2005-04-05 | 2006-04-05 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008538282A true JP2008538282A (ja) | 2008-10-23 |
| JP2008538282A5 JP2008538282A5 (https=) | 2010-10-14 |
Family
ID=37074090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008505508A Pending JP2008538282A (ja) | 2005-04-05 | 2006-04-05 | 装置および循環腫瘍細胞および他の粒子の濃縮および変更のための方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20070099207A1 (https=) |
| EP (2) | EP1874920A4 (https=) |
| JP (1) | JP2008538282A (https=) |
| GB (1) | GB2427468B (https=) |
| WO (1) | WO2006108087A2 (https=) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012002447A1 (ja) * | 2010-06-30 | 2012-01-05 | 武田薬品工業株式会社 | 変異ポリヌクレオチドの検出方法 |
| JP2012504956A (ja) * | 2008-10-10 | 2012-03-01 | セントレ ナショナル デ ラ レシェルシェ サイエンティフィーク−ディーエーイー | 細胞ソート・デバイス |
| JP2012529983A (ja) * | 2009-06-19 | 2012-11-29 | コミサリア ア レネルジィ アトミーク エ オ ゼネ ルジイ アルテアナティーフ | 液相間で成分を移動させるマイクロ流体システム及び対応する方法、並びに上記成分を抽出するための上記システムの使用 |
| JP2013505429A (ja) * | 2009-09-21 | 2013-02-14 | マウント シナイ ホスピタル | 甲状腺癌を診断および処置するための方法および組成物 |
| WO2012151501A3 (en) * | 2011-05-05 | 2013-04-25 | Anpac Bio-Medical Science Co., Ltd. | Apparatus for detecting tumor cells |
| JP2017000921A (ja) * | 2015-06-05 | 2017-01-05 | 国立大学法人 東京大学 | 曲げ弾性係数が小さい粒子の分離捕捉装置 |
| JP2021510516A (ja) * | 2018-01-19 | 2021-04-30 | インターナショナル・ビジネス・マシーンズ・コーポレーションInternational Business Machines Corporation | 粒子の精製および分画のための方法およびマイクロ流体装置 |
| US11085923B2 (en) | 2011-03-24 | 2021-08-10 | Anpac Bio-Medical Science Co., Ltd | Micro-devices for disease detection |
| JPWO2022070841A1 (https=) * | 2020-09-29 | 2022-04-07 | ||
| US11458474B2 (en) | 2018-01-19 | 2022-10-04 | International Business Machines Corporation | Microfluidic chips with one or more vias |
| US11566982B2 (en) | 2018-01-19 | 2023-01-31 | International Business Machines Corporation | Microscale and mesoscale condenser devices |
| JPWO2023189095A1 (https=) * | 2022-03-28 | 2023-10-05 |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6913697B2 (en) | 2001-02-14 | 2005-07-05 | Science & Technology Corporation @ Unm | Nanostructured separation and analysis devices for biological membranes |
| CA2500392C (en) | 2002-09-27 | 2012-11-27 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
| US20090136982A1 (en) * | 2005-01-18 | 2009-05-28 | Biocept, Inc. | Cell separation using microchannel having patterned posts |
| US8158410B2 (en) | 2005-01-18 | 2012-04-17 | Biocept, Inc. | Recovery of rare cells using a microchannel apparatus with patterned posts |
| JP2008526251A (ja) | 2005-01-18 | 2008-07-24 | バイオセプト インコーポレイティッド | パターン化されたポストを有するマイクロチャネルを用いた細胞分離 |
| US20060252087A1 (en) * | 2005-01-18 | 2006-11-09 | Biocept, Inc. | Recovery of rare cells using a microchannel apparatus with patterned posts |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US20070059718A1 (en) * | 2005-09-15 | 2007-03-15 | Mehmet Toner | Systems and methods for enrichment of analytes |
| US20070059716A1 (en) * | 2005-09-15 | 2007-03-15 | Ulysses Balis | Methods for detecting fetal abnormality |
| US20110052570A1 (en) * | 2005-10-26 | 2011-03-03 | Children's Medical Center Corporation | Method to prognose response to anti-egfr therapeutics |
| US7695956B2 (en) | 2006-01-12 | 2010-04-13 | Biocept, Inc. | Device for cell separation and analysis and method of using |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| WO2007147074A2 (en) | 2006-06-14 | 2007-12-21 | Living Microsystems, Inc. | Use of highly parallel snp genotyping for fetal diagnosis |
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| EP2589668A1 (en) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Rare cell analysis using sample splitting and DNA tags |
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| WO2008153692A2 (en) * | 2007-05-22 | 2008-12-18 | The Brigham And Women's Hospital, Inc. | Microrna expression profiling of cerebrospinal fluid |
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| US8008032B2 (en) | 2008-02-25 | 2011-08-30 | Cellective Dx Corporation | Tagged ligands for enrichment of rare analytes from a mixed sample |
| EP2291509B1 (en) | 2008-05-16 | 2023-11-15 | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College | Microfluidic isolation of tumor cells or other rare cells from whole blood or other liquids |
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| HUE031848T2 (en) | 2008-09-20 | 2017-08-28 | Univ Leland Stanford Junior | Non-invasive diagnosis of fetal aneuploidy by sequencing |
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| WO2010132795A2 (en) * | 2009-05-15 | 2010-11-18 | The General Hospital Corporation | Systems, devices, and methods for specific capture and release of biological sample components |
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| CN102140518B (zh) * | 2011-01-18 | 2013-02-06 | 杭州迪安医学检验中心有限公司 | 肺癌相关表皮生长因子受体egfr外显子突变定量检测试剂盒及方法 |
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| WO2023189095A1 (ja) * | 2022-03-28 | 2023-10-05 | 国立大学法人茨城大学 | 白血球捕捉デバイス |
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| JP7729536B2 (ja) | 2022-03-28 | 2025-08-26 | 国立大学法人茨城大学 | 白血球捕捉デバイス |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006108087A2 (en) | 2006-10-12 |
| EP2594631A1 (en) | 2013-05-22 |
| US20070099207A1 (en) | 2007-05-03 |
| GB0612649D0 (en) | 2006-08-16 |
| EP1874920A4 (en) | 2009-11-04 |
| GB2427468B (en) | 2011-03-02 |
| GB2427468A (en) | 2006-12-27 |
| WO2006108087A3 (en) | 2009-06-04 |
| US20110306043A1 (en) | 2011-12-15 |
| EP1874920A2 (en) | 2008-01-09 |
| HK1154422A1 (en) | 2012-04-20 |
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