JP2008537734A - 経口で用いられる適合溶質を含む薬剤 - Google Patents

経口で用いられる適合溶質を含む薬剤 Download PDF

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Publication number
JP2008537734A
JP2008537734A JP2008501213A JP2008501213A JP2008537734A JP 2008537734 A JP2008537734 A JP 2008537734A JP 2008501213 A JP2008501213 A JP 2008501213A JP 2008501213 A JP2008501213 A JP 2008501213A JP 2008537734 A JP2008537734 A JP 2008537734A
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JP
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Prior art keywords
diglycerol
compatible solutes
drug
treatment
prevention
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2008501213A
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English (en)
Japanese (ja)
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JP2008537734A5 (enExample
Inventor
シュヴァルツ,トーマス
レンツェン,ゲオルク
クルトマン,ジャン
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Bitop AG
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Bitop AG
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Publication of JP2008537734A publication Critical patent/JP2008537734A/ja
Publication of JP2008537734A5 publication Critical patent/JP2008537734A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2008501213A 2005-03-12 2006-03-13 経口で用いられる適合溶質を含む薬剤 Pending JP2008537734A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005011442 2005-03-12
PCT/EP2006/002286 WO2006097263A2 (de) 2005-03-12 2006-03-13 Kompatible solute enthaltende mittel zur oralen verwendung

Publications (2)

Publication Number Publication Date
JP2008537734A true JP2008537734A (ja) 2008-09-25
JP2008537734A5 JP2008537734A5 (enExample) 2009-04-30

Family

ID=36992085

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008501213A Pending JP2008537734A (ja) 2005-03-12 2006-03-13 経口で用いられる適合溶質を含む薬剤

Country Status (4)

Country Link
US (1) US9089568B2 (enExample)
EP (1) EP1858519B1 (enExample)
JP (1) JP2008537734A (enExample)
WO (1) WO2006097263A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102210685A (zh) * 2011-04-29 2011-10-12 济南环肽医药科技有限公司 四氢嘧啶及其衍生物在制备预防和治疗化疗药物引发的消化道炎症药物中的应用

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006056766A1 (de) * 2006-12-01 2008-06-05 Bitop Ag Verwendung von kompatiblen Soluten
DE102007040615A1 (de) * 2007-08-27 2009-03-05 Bitop Ag Osmolyte zur Behandlung von allergisch oder viral bedingten Atemwegserkrankungen
DE102008006780A1 (de) * 2008-01-30 2009-08-06 Bitop Ag Verwendung von Tetrahydropyrimidinen
KR101514422B1 (ko) 2008-05-20 2015-04-24 아주대학교산학협력단 해양미생물 대사체를 유효성분으로 포함하는 당뇨병 예방또는 치료용 조성물
DE102008039231A1 (de) * 2008-08-22 2010-02-25 Bitop Ag Verwendung von Glucosylglycerol
CN102258520B (zh) * 2011-04-29 2012-10-03 济南环肽医药科技有限公司 一种预防或治疗化疗引发的膀胱炎的药物组合物
CN102210681B (zh) * 2011-04-29 2013-01-30 山东弘立医学动物实验研究有限公司 四氢嘧啶及其衍生物在制备治疗消化道疾病药物中的应用
CN102228445A (zh) * 2011-06-30 2011-11-02 山东弘立医学动物实验研究有限公司 一种四氢嘧啶或四氢嘧啶衍生物的注射用冻干粉
CN102283845B (zh) * 2011-07-07 2012-10-03 济南环肽医药科技有限公司 1,4,5,6-四氢-2-甲基-4-嘧啶羧酸及1,4,5,6-四氢-2-甲基-5-羟基-4-嘧啶羧酸在制备肺结核治疗药物中的应用
FR3022458A1 (fr) * 2014-06-23 2015-12-25 Univ Bretagne Occidentale Utilisation du mannosylglycerate et ses derives comme agent immunostimulant
TWI629265B (zh) * 2017-04-13 2018-07-11 元智大學 Reactive raw humectant and its preparation

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WO1992000744A1 (en) * 1990-07-04 1992-01-23 Perstorp Ab THE USE OF INOSITOLMONOPHOSPHATE FOR THE PREPARING OF A MEDICAMENT EFFECTIVE AS A NEUROPEPTIDE η-ANTAGONIST
JPH1017478A (ja) * 1996-06-28 1998-01-20 Roussel Morishita Kk 潰瘍性大腸炎の予防又は治療剤
JP2000508331A (ja) * 1996-04-12 2000-07-04 ホイジンガー,デイーター 感染、炎症または免疫障害の影響を治療するためのオスモライトの使用
DE10006578A1 (de) * 2000-02-14 2001-08-23 Bitop Gmbh Verwendung von kompatiblen Soluten als Inhibitoren des enzymatischen Abbaus von makromolekularen Biopolymeren
JP2003531833A (ja) * 2000-04-12 2003-10-28 ビトプ アクチェンゲゼルシャフト フューア ビオテヒニシェ オプティミールング フリーラジカル捕捉特性を有する物質としての適合溶質の使用
JP2004508315A (ja) * 2000-09-07 2004-03-18 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング オーラルケア用のエクトインおよびエクトイン誘導体の使用

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AT370284B (de) 1978-07-13 1983-03-10 Sp Kt Bjuro Dezintegrator Verfahren zur herstellung eines nahrungsmittels fuer menschen und tiere
US5122369A (en) 1990-03-30 1992-06-16 Harmony Health Products, Inc. Nutrient composition for preventing hair loss
IL100810A (en) * 1992-01-30 1996-12-05 Yeda Res & Dev Pharmaceutical preparations including 2 - methyl - carboxy - 5 - hydroxy - tetrahydropyrimidine and / or 2 - methyl - 4 - carboxy - tetrahydropyrimidine, plywood methods
US5834473A (en) * 1993-04-29 1998-11-10 Cultor, Ltd. Method for treating coccidiosis
DE4342560A1 (de) 1993-12-14 1995-06-22 Marbert Gmbh Ectoin und Ectoinderivate als Feuchtigkeitsspender in Kosmetikprodukten
DE4428665C2 (de) * 1994-08-12 1997-02-06 Zinser Textilmaschinen Gmbh Vorrichtung zum selbsttätigen Spulenwechsel an einer Spinnereimaschine
CN1117824A (zh) 1995-05-22 1996-03-06 苏捷 复合氨基酸饮料
US5880098A (en) * 1996-04-12 1999-03-09 Pharmacia & Upjohn Aktiebolag Therapeutic treatment
US20030157040A1 (en) 1998-08-01 2003-08-21 Merck Patent Gmbh Use of ectoine or ectoine derivatives in cosmetic formulations
EP1127141A1 (de) 1998-11-07 2001-08-29 Stefan Barth Verfahren zur expression rekombinanter proteine unter ausnutzung der wirkung von stress und stressantwortmechanismen in gegenwart kompatibler solute
US6080401A (en) * 1998-11-19 2000-06-27 Reddy; Malireddy S. Herbal and pharmaceutical drugs enhanced with probiotics
DE19925615A1 (de) * 1999-06-04 2000-12-07 Erwin A Galinski Verfahren zur Produktion von Ectoinen (1,4,5,6-Tetrahydro-2-methyl-4-pyrimidin-carbonsäure und 1,4,5,6-Tetrahydro-2-methyl-5-hydroxy-4- pyrimidincarbonsäure) in nicht-halophilen Organismen unter Verwendung salzarmer Medien
JP2003501479A (ja) * 1999-06-12 2003-01-14 ビトプ ゲゼルシャフト ミット ベシュレンクテル ハフツング 薬 剤
CZ289242B6 (cs) 2000-08-10 2001-12-12 Eduard Dr. Sardaryan Prostředek s profylaktickým protinádorovým účinkem
JP2004506676A (ja) * 2000-08-18 2004-03-04 ビトプ アクチェンゲゼルシャフト フューア ビオテヒニシェ オプティミールング 化粧品用調合物
DE10044985B4 (de) 2000-09-11 2019-08-14 Merck Patent Gmbh Verwendung von Ectoin oder Ectoin-Derivaten zum Schutz vor Allergenen
US20020147153A1 (en) 2001-02-14 2002-10-10 Functional Foods, Inc. Nutritional supplement to alleviate symptoms associated with reduced levels of serotonin
DE10330243A1 (de) * 2003-07-03 2005-01-20 bitop Aktiengesellschaft für biotechnische Optimierung Verwendung von aus extremophilen Bakterien gewonnenen Osmolyten zur Herstellung von Arzneimitteln zur äusserlichen Behandlung der Neurodermitis
DE10330768A1 (de) * 2003-07-07 2005-02-24 bitop Aktiengesellschaft für biotechnische Optimierung Verwendung von aus extremophilen Bakterien gewonnenen Osmolyten zur Herstellung von inhalierbaren Arzneimitteln zur Prophylaxe und Behandlung pulmonaler und kardiovaskulärer Erkrankungen, sowie eines Osmolyte als Wirkstoffbestandteil enthaltende Inhalationsvorrichtung
DE102004049062A1 (de) * 2004-03-30 2005-10-13 bitop Aktiengesellschaft für biotechnische Optimierung Topische Zubereitung zur Anwendung auf der Haut enthaltend natürliches Öl der Nachtkerze (Oenothera biennis) (=Oleum Oenothera) und Osmolyte aus extremophilen Mikroorganismen
DE102007040615A1 (de) * 2007-08-27 2009-03-05 Bitop Ag Osmolyte zur Behandlung von allergisch oder viral bedingten Atemwegserkrankungen
DE102007052380A1 (de) * 2007-10-31 2009-05-07 Bitop Ag Osmolythaltige Zubereitungen zur Anwendung bei trockenen Schleimhäuten
DE102008039231A1 (de) * 2008-08-22 2010-02-25 Bitop Ag Verwendung von Glucosylglycerol

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WO1992000744A1 (en) * 1990-07-04 1992-01-23 Perstorp Ab THE USE OF INOSITOLMONOPHOSPHATE FOR THE PREPARING OF A MEDICAMENT EFFECTIVE AS A NEUROPEPTIDE η-ANTAGONIST
JP2000508331A (ja) * 1996-04-12 2000-07-04 ホイジンガー,デイーター 感染、炎症または免疫障害の影響を治療するためのオスモライトの使用
JPH1017478A (ja) * 1996-06-28 1998-01-20 Roussel Morishita Kk 潰瘍性大腸炎の予防又は治療剤
DE10006578A1 (de) * 2000-02-14 2001-08-23 Bitop Gmbh Verwendung von kompatiblen Soluten als Inhibitoren des enzymatischen Abbaus von makromolekularen Biopolymeren
JP2003531833A (ja) * 2000-04-12 2003-10-28 ビトプ アクチェンゲゼルシャフト フューア ビオテヒニシェ オプティミールング フリーラジカル捕捉特性を有する物質としての適合溶質の使用
JP2004508315A (ja) * 2000-09-07 2004-03-18 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング オーラルケア用のエクトインおよびエクトイン誘導体の使用

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102210685A (zh) * 2011-04-29 2011-10-12 济南环肽医药科技有限公司 四氢嘧啶及其衍生物在制备预防和治疗化疗药物引发的消化道炎症药物中的应用
CN102210685B (zh) * 2011-04-29 2013-01-30 济南环肽医药科技有限公司 四氢嘧啶及其衍生物在制备预防和治疗化疗药物引发的口腔粘膜炎药物中的应用

Also Published As

Publication number Publication date
EP1858519A2 (de) 2007-11-28
EP1858519B1 (de) 2013-02-20
US20090060876A1 (en) 2009-03-05
WO2006097263A2 (de) 2006-09-21
WO2006097263A3 (de) 2007-02-22
US9089568B2 (en) 2015-07-28

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