JP2008535835A5 - - Google Patents

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Publication number
JP2008535835A5
JP2008535835A5 JP2008505262A JP2008505262A JP2008535835A5 JP 2008535835 A5 JP2008535835 A5 JP 2008535835A5 JP 2008505262 A JP2008505262 A JP 2008505262A JP 2008505262 A JP2008505262 A JP 2008505262A JP 2008535835 A5 JP2008535835 A5 JP 2008535835A5
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JP
Japan
Prior art keywords
amino
formula
compound
thiazolo
thio
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Granted
Application number
JP2008505262A
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English (en)
Japanese (ja)
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JP5165553B2 (ja
JP2008535835A (ja
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Priority claimed from PCT/SE2006/000399 external-priority patent/WO2006107258A1/en
Publication of JP2008535835A publication Critical patent/JP2008535835A/ja
Publication of JP2008535835A5 publication Critical patent/JP2008535835A5/ja
Application granted granted Critical
Publication of JP5165553B2 publication Critical patent/JP5165553B2/ja
Active legal-status Critical Current
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JP2008505262A 2005-04-06 2006-04-03 新規な５−置換された７−アミノ［１，３］チアゾロ［４，５−ｄ］ピリミジン誘導体 Active JP5165553B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0500767 2005-04-06
SE0500767-9 2005-04-06
PCT/SE2006/000399 WO2006107258A1 (en) 2005-04-06 2006-04-03 Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives

Publications (3)

Publication Number Publication Date
JP2008535835A JP2008535835A (ja) 2008-09-04
JP2008535835A5 true JP2008535835A5 (OSRAM) 2009-06-04
JP5165553B2 JP5165553B2 (ja) 2013-03-21

Family

ID=37073739

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008505262A Active JP5165553B2 (ja) 2005-04-06 2006-04-03 新規な５−置換された７−アミノ［１，３］チアゾロ［４，５−ｄ］ピリミジン誘導体

Country Status (30)

Country Link
US (2) US7947693B2 (OSRAM)
EP (1) EP1869056B1 (OSRAM)
JP (1) JP5165553B2 (OSRAM)
KR (1) KR101335055B1 (OSRAM)
CN (1) CN101193897B (OSRAM)
AR (1) AR055890A1 (OSRAM)
AT (1) ATE487727T1 (OSRAM)
AU (1) AU2006231836B2 (OSRAM)
BR (1) BRPI0609738A2 (OSRAM)
CA (1) CA2604017C (OSRAM)
CY (1) CY1111316T1 (OSRAM)
DE (1) DE602006018124D1 (OSRAM)
DK (1) DK1869056T3 (OSRAM)
ES (1) ES2354450T3 (OSRAM)
HR (1) HRP20110047T1 (OSRAM)
IL (1) IL185912A0 (OSRAM)
MX (1) MX2007012060A (OSRAM)
NO (1) NO20075603L (OSRAM)
NZ (1) NZ561460A (OSRAM)
PL (1) PL1869056T3 (OSRAM)
PT (1) PT1869056E (OSRAM)
RS (1) RS51581B (OSRAM)
RU (1) RU2419623C2 (OSRAM)
SA (1) SA06270072B1 (OSRAM)
SI (1) SI1869056T1 (OSRAM)
TW (1) TW200714605A (OSRAM)
UA (1) UA90707C2 (OSRAM)
UY (1) UY29454A1 (OSRAM)
WO (1) WO2006107258A1 (OSRAM)
ZA (1) ZA200708187B (OSRAM)

Families Citing this family (23)

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Publication number Priority date Publication date Assignee Title
EP1806145B1 (en) 2004-10-29 2017-08-16 Eisai R&D Management Co., Ltd. Remedy for inflammatory diseases
AR053347A1 (es) 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
TW200820973A (en) 2006-09-29 2008-05-16 Astrazeneca Ab Novel compounds 480
EP2069365A4 (en) * 2006-09-29 2011-11-02 Astrazeneca Ab NOVEL [1, 3] THIAZOLO [4,5-D] PYRIMIDIN-2 (3H) -AMINE 5,7-DISUBSTITUTED DERIVATIVES AND THEIR USE IN THERAPY
CN101959866B (zh) 2008-03-07 2013-10-02 方济各安吉利克化学联合股份有限公司 1-苄基-3-羟基甲基吲唑衍生物及其在治疗基于mcp-1和cx3cr1表达的疾病中的用途
US7919518B2 (en) 2008-03-07 2011-04-05 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40
DK2262778T5 (da) 2008-03-07 2020-06-08 Acraf 1-benzyl-3-hydroxymethylindazolderivativer og brug deraf i behandling af sygdomme baseret på ekspression af mcp-1, cx3cr1 og p40
TW201100411A (en) 2009-05-21 2011-01-01 Chlorion Pharma Inc Pyrimidines as novel therapeutic agents
JO3437B1 (ar) 2009-10-30 2019-10-20 Esai R & D Man Co Ltd أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها
US8435993B2 (en) 2010-12-07 2013-05-07 Philadelphia Health And Education Corporation Methods of inhibiting metastasis from cancer
TWI543975B (zh) 2011-09-13 2016-08-01 Eisai R&D Man Co Ltd Pyrrolidin-3-yl acetic acid derivatives
US8476301B2 (en) 2011-09-13 2013-07-02 Eisai R&D Management Co., Ltd. Pyrrolidin-3-ylacetic acid derivative
AU2014231863B2 (en) 2013-03-12 2017-07-27 Eisai R&D Management Co., Ltd. Salt of pyrrolidin-3-yl acetic acid derivative and crystals thereof
BR112016006319A2 (pt) 2013-09-27 2017-08-01 Nimbus Iris Inc inibidores de irak e usos dos mesmos
US20180222922A1 (en) * 2015-06-08 2018-08-09 The Johns Hopkins University Radiofluorinated 7-amino-5-thio-thiazolo[4,5-d]pyrimidines for imaging fractalkine receptor (cx3cr1)
US11267817B2 (en) 2017-05-02 2022-03-08 Drexel University Substituted pyrrolo[1,2-a]quinoxalin-4(5H)-ones as CX3CR1 antagonists
GB201807898D0 (en) * 2018-05-15 2018-06-27 Kancera Ab New processes and products with increased chiral purity
GB201811169D0 (en) 2018-07-06 2018-08-29 Kancera Ab New compounds
GB202006849D0 (en) 2020-05-08 2020-06-24 Kancera Ab New use
EP4605388A1 (en) 2022-10-19 2025-08-27 Astrazeneca AB <sup2/>? <sub2/>?3?2,4,6-trisubstituted 1,3,5-triazines as modulators of cxcr1
WO2025219939A1 (en) 2024-04-17 2025-10-23 Astrazeneca Ab Salts and polymorphs of cx3cr1 modulators
WO2025219947A1 (en) 2024-04-18 2025-10-23 Astrazeneca Ab Thio-substituted 1,3,5-triazine cx3cr1 modulators
WO2025219950A1 (en) 2024-04-18 2025-10-23 Astrazeneca Ab Small molecule cx3cr1 modulators

Family Cites Families (25)

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BE543978A (OSRAM) * 1955-01-03
US4698327A (en) * 1985-04-25 1987-10-06 Eli Lilly And Company Novel glycopeptide derivatives
US4643987A (en) * 1985-08-14 1987-02-17 Eli Lilly And Company Modified glycopeptides
US4639433A (en) * 1985-08-14 1987-01-27 Eli Lilly And Company Glycopeptide derivatives
IL96603A (en) * 1989-12-13 1998-02-08 Lilly Co Eli Antibacterial glycopeptide derivatives, process for their preparation and pharmaceutical compositions containing them
US5202328A (en) * 1991-03-06 1993-04-13 Merck & Co., Inc. Substituted fused pyrimidinones
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
ES2172840T3 (es) * 1997-07-18 2002-10-01 Hoffmann La Roche Derivados de 5h-tiazolo(3,2-a)pirimidina.
WO1999051608A1 (en) * 1998-04-03 1999-10-14 Du Pont Pharmaceuticals Company THIAZOLO[4,5-d]PYRIMIDINES AND PYRIDINES AS CORTICOTROPIN RELEASING FACTOR (CRF) ANTAGONISTS
EP1073447B1 (en) 1998-05-01 2007-05-09 Eli Lilly And Company N1-modified glycopeptides
SE9802729D0 (sv) 1998-08-13 1998-08-13 Astra Pharma Prod Novel Compounds
SE9903544D0 (sv) 1999-10-01 1999-10-01 Astra Pharma Prod Novel compounds
DE60101372T2 (de) * 2000-02-11 2004-10-14 Astrazeneca Ab Pyrimidinverbindungen und ihre verwendung als modulatoren der chemokin-rezeptor-aktivität
GB2359081A (en) * 2000-02-11 2001-08-15 Astrazeneca Uk Ltd Pharmaceutically active thiazolopyrimidines
GB2359551A (en) 2000-02-23 2001-08-29 Astrazeneca Uk Ltd Pharmaceutically active pyrimidine derivatives
RU2340611C2 (ru) * 2000-09-15 2008-12-10 Вертекс Фармасьютикалз Инкорпорейтед Производные пиразола, используемые в качестве ингибиторов протеинкиназы
SE0004110L (sv) * 2000-11-10 2002-05-11 Forsheda Ab Tätningsring
SE0101082D0 (sv) 2001-03-27 2001-03-27 Astrazeneca Ab Novel use
SE0101322D0 (sv) 2001-04-12 2001-04-12 Astrazeneca Ab Novel compounds
GB0221829D0 (en) 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
GB0221828D0 (en) 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
DK2526996T3 (da) * 2002-12-20 2019-12-02 Xeris Pharmaceuticals Inc Formulering til intrakutan injektion
MXPA06003792A (es) * 2003-10-07 2006-06-14 Astrazeneca Ab Nuevas 4-amino-tiazolo[4,5-d]-pirimidinas 2-sustituidas, utiles como antagonistas del receptor de quimiocina, especialmente cx3cr1.
WO2006064228A2 (en) * 2004-12-17 2006-06-22 Astrazeneca Ab Thiazolopyramidine compounds for the modulation of chemokine receptor activity
AR053347A1 (es) * 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos

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