JP2008529539A5 - - Google Patents
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- JP2008529539A5 JP2008529539A5 JP2007555430A JP2007555430A JP2008529539A5 JP 2008529539 A5 JP2008529539 A5 JP 2008529539A5 JP 2007555430 A JP2007555430 A JP 2007555430A JP 2007555430 A JP2007555430 A JP 2007555430A JP 2008529539 A5 JP2008529539 A5 JP 2008529539A5
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- JP
- Japan
- Prior art keywords
- composition
- amino acid
- acid sequence
- polypeptide
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65392805P | 2005-02-18 | 2005-02-18 | |
| US60/653,928 | 2005-02-18 | ||
| PCT/CA2005/001158 WO2006086870A1 (en) | 2005-02-18 | 2005-07-21 | Aprotinin polypeptides for transporting a compound across the blood-brain barrier |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011004842A Division JP5462193B2 (ja) | 2005-02-18 | 2011-01-13 | 血液脳関門を介して化合物を輸送するためのアプロチニンポリペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008529539A JP2008529539A (ja) | 2008-08-07 |
| JP2008529539A5 true JP2008529539A5 (https=) | 2008-09-18 |
| JP5175108B2 JP5175108B2 (ja) | 2013-04-03 |
Family
ID=36916132
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007555430A Expired - Fee Related JP5175108B2 (ja) | 2005-02-18 | 2005-07-21 | 血液脳関門を介して化合物を輸送するためのアプロチニンポリペプチド |
| JP2011004842A Expired - Fee Related JP5462193B2 (ja) | 2005-02-18 | 2011-01-13 | 血液脳関門を介して化合物を輸送するためのアプロチニンポリペプチド |
| JP2013245690A Pending JP2014088386A (ja) | 2005-02-18 | 2013-11-28 | 血液脳関門を介して化合物を輸送するためのアプロチニンポリペプチド |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011004842A Expired - Fee Related JP5462193B2 (ja) | 2005-02-18 | 2011-01-13 | 血液脳関門を介して化合物を輸送するためのアプロチニンポリペプチド |
| JP2013245690A Pending JP2014088386A (ja) | 2005-02-18 | 2013-11-28 | 血液脳関門を介して化合物を輸送するためのアプロチニンポリペプチド |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US7557182B2 (https=) |
| EP (2) | EP2360258B1 (https=) |
| JP (3) | JP5175108B2 (https=) |
| CN (2) | CN101160403B (https=) |
| AT (1) | ATE551422T1 (https=) |
| AU (1) | AU2005327497B2 (https=) |
| BR (1) | BRPI0520032A2 (https=) |
| CA (1) | CA2597958C (https=) |
| CY (1) | CY1113299T1 (https=) |
| DK (2) | DK1859041T4 (https=) |
| ES (2) | ES2383901T5 (https=) |
| MX (1) | MX2007010113A (https=) |
| PL (2) | PL1859041T5 (https=) |
| PT (2) | PT2360258E (https=) |
| RU (2) | RU2408605C2 (https=) |
| SI (2) | SI1859041T2 (https=) |
| WO (1) | WO2006086870A1 (https=) |
| ZA (1) | ZA200706917B (https=) |
Families Citing this family (60)
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| US7906625B2 (en) * | 2005-01-24 | 2011-03-15 | Amgen Inc. | Humanized anti-amyloid antibody |
| RU2408605C2 (ru) * | 2005-02-18 | 2011-01-10 | Анджиокем Инк. | Полипептид, способный преодолевать гематоэнцефалический барьер, и его конъюгат |
| US20090016959A1 (en) * | 2005-02-18 | 2009-01-15 | Richard Beliveau | Delivery of antibodies to the central nervous system |
| ES2744225T3 (es) | 2005-07-15 | 2020-02-24 | Angiochem Inc | Uso de polipéptidos de aprotinina como portadores en conjugados farmacéuticos |
| JP2010506860A (ja) | 2006-10-19 | 2010-03-04 | アンジオケム,インコーポレーテッド | P−糖タンパク質機能を刺激するための化合物およびその使用 |
| PT2164866E (pt) * | 2007-05-29 | 2014-08-04 | Angiochem Inc | Polipéptidos de tipo aprotinina para administrar agentes conjugados com os mesmos aos tecidos |
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| BRPI0821310A2 (pt) * | 2007-12-20 | 2015-06-16 | Angiochem Inc | Conjugados polipeptídeos-ácido nucleico e usos dos mesmos |
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| CA2745524C (en) * | 2008-12-05 | 2020-06-09 | Angiochem Inc. | Conjugates of neurotensin or neurotensin analogs and uses thereof |
| CN102348723A (zh) * | 2008-12-05 | 2012-02-08 | 安吉奥开米公司 | 肽治疗剂轭合物及其应用 |
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| US20130280281A1 (en) * | 2010-07-02 | 2013-10-24 | Jean-Paul Castaigne | Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof |
| JP2013530993A (ja) | 2010-07-02 | 2013-08-01 | アンジオケム インコーポレーテッド | 治療用コンジュゲートのための短く且つd−アミノ酸を含有するポリペプチドおよびその使用 |
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| JP2015526434A (ja) | 2012-08-14 | 2015-09-10 | アンジオケム インコーポレーテッド | ペプチド−デンドリマーコンジュゲート及びその使用 |
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| US10370432B2 (en) | 2014-10-03 | 2019-08-06 | University Of Massachusetts | Heterologous targeting peptide grafted AAVS |
| WO2016061801A1 (zh) * | 2014-10-24 | 2016-04-28 | 中国科学技术大学 | 用于淀粉样蛋白显像的血管肽及其衍生物 |
| JP6474893B2 (ja) * | 2014-11-06 | 2019-02-27 | オーエスイー・イミュノセラピューティクス | 脳転移の処置のための治療用マルチペプチドt特異的免疫療法 |
| EP3256170B1 (en) | 2015-02-13 | 2020-09-23 | University of Massachusetts | Compositions and methods for transient delivery of nucleases |
| JP6612063B2 (ja) * | 2015-06-11 | 2019-11-27 | 国立大学法人滋賀医科大学 | 悪性神経膠腫分子標的ペプチド |
| EP3307326B9 (en) | 2015-06-15 | 2021-02-24 | Angiochem Inc. | Methods for the treatment of leptomeningeal carcinomatosis |
| PL417159A1 (pl) | 2016-05-11 | 2017-11-20 | Instytut Biologii Doświadczalnej Im. Marcelego Nenckiego | Koniugaty białka prionowego z dendrymerami do zastosowania w leczeniu choroby Alzheimera |
| EP3481413A4 (en) * | 2016-07-08 | 2020-01-08 | Askgene Pharma, Inc. | FUSION PROTEIN WITH LEPTIN AND METHOD FOR THE PRODUCTION AND USE THEREOF |
| US10702589B2 (en) | 2016-10-04 | 2020-07-07 | Ann And Robert H. Lurie Children's Hospital Of Chicago | Compositions and methods of treating neurological disorder and stress-induced conditions |
| WO2018127927A1 (en) | 2017-01-09 | 2018-07-12 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| WO2019130319A1 (en) | 2018-01-01 | 2019-07-04 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| US10688191B2 (en) | 2018-01-19 | 2020-06-23 | Hr Biomed, Llc | Delivery of a chemotherapy agent across the blood-brain barrier |
| CN109666973B (zh) * | 2018-11-21 | 2022-11-04 | 北京大学 | 一种穿过血脑屏障的肽库及其筛选方法 |
| CN115484970A (zh) * | 2020-03-18 | 2022-12-16 | 斯坦福国际研究院 | 到中枢神经系统的分子转运系统 |
| CA3128035A1 (en) | 2020-08-13 | 2022-02-13 | Bioasis Technologies, Inc. | Combination therapies for delivery across the blood brain barrier |
| WO2022156531A1 (zh) * | 2021-01-19 | 2022-07-28 | 中国人民解放军军事科学院军事医学研究院 | 一种能够透过生物屏障的动力蛋白结合肽及其应用 |
| CN112851789B (zh) * | 2021-02-04 | 2022-10-18 | 大理大学 | 一种脑靶向hiv进入抑制剂多肽及其应用 |
| AU2022222778A1 (en) * | 2021-02-22 | 2023-08-31 | Yale University | Targeted bifunctional degraders and methods using same |
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-
2005
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- 2005-07-21 EP EP11000946.1A patent/EP2360258B1/en not_active Expired - Lifetime
- 2005-07-21 PT PT110009461T patent/PT2360258E/pt unknown
- 2005-07-21 DK DK05770546.9T patent/DK1859041T4/en active
- 2005-07-21 WO PCT/CA2005/001158 patent/WO2006086870A1/en not_active Ceased
- 2005-07-21 DK DK11000946.1T patent/DK2360258T3/en active
- 2005-07-21 SI SI200531536T patent/SI1859041T2/sl unknown
- 2005-07-21 PL PL11000946T patent/PL2360258T3/pl unknown
- 2005-07-21 CN CN200580049237.8A patent/CN101160403B/zh not_active Expired - Fee Related
- 2005-07-21 US US11/185,947 patent/US7557182B2/en not_active Expired - Lifetime
- 2005-07-21 MX MX2007010113A patent/MX2007010113A/es active IP Right Grant
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- 2005-07-21 CN CN201410334833.1A patent/CN104311653B/zh not_active Expired - Fee Related
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- 2005-07-21 BR BRPI0520032-6A patent/BRPI0520032A2/pt not_active Application Discontinuation
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