JP2008526996A5 - - Google Patents
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- Publication number
- JP2008526996A5 JP2008526996A5 JP2007551428A JP2007551428A JP2008526996A5 JP 2008526996 A5 JP2008526996 A5 JP 2008526996A5 JP 2007551428 A JP2007551428 A JP 2007551428A JP 2007551428 A JP2007551428 A JP 2007551428A JP 2008526996 A5 JP2008526996 A5 JP 2008526996A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- group
- alkyl
- alkynyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64410305P | 2005-01-14 | 2005-01-14 | |
| US60/644,103 | 2005-01-14 | ||
| US74282105P | 2005-12-06 | 2005-12-06 | |
| US60/742,821 | 2005-12-06 | ||
| US75098505P | 2005-12-16 | 2005-12-16 | |
| US60/750,985 | 2005-12-16 | ||
| PCT/US2006/001341 WO2006076644A2 (en) | 2005-01-14 | 2006-01-13 | Heteroaryl sulfonamides and ccr2 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008526996A JP2008526996A (ja) | 2008-07-24 |
| JP2008526996A5 true JP2008526996A5 (enExample) | 2012-05-17 |
| JP5253815B2 JP5253815B2 (ja) | 2013-07-31 |
Family
ID=36678244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007551428A Expired - Lifetime JP5253815B2 (ja) | 2005-01-14 | 2006-01-13 | ヘテロアリールスルホンアミドおよびccr2 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060173019A1 (enExample) |
| EP (3) | EP1838674B9 (enExample) |
| JP (1) | JP5253815B2 (enExample) |
| AT (1) | ATE503741T1 (enExample) |
| AU (1) | AU2006204750C1 (enExample) |
| CA (1) | CA2594726C (enExample) |
| DE (1) | DE602006020979D1 (enExample) |
| DK (2) | DK2354126T3 (enExample) |
| ES (1) | ES2440965T3 (enExample) |
| IL (1) | IL184539A (enExample) |
| MX (1) | MX2007008474A (enExample) |
| PL (2) | PL2354126T3 (enExample) |
| WO (1) | WO2006076644A2 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1507756B1 (en) | 2002-05-24 | 2015-07-22 | Millennium Pharmaceuticals, Inc. | Ccr9 inhibitors and methods of use thereof |
| DK1798223T4 (da) | 2002-11-18 | 2014-09-22 | Chemocentryx Inc | Arylsulfonamider |
| JP2007537275A (ja) * | 2004-05-12 | 2007-12-20 | ケモセントリックス, インコーポレイテッド | アリールスルホンアミド |
| US7622583B2 (en) | 2005-01-14 | 2009-11-24 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2 |
| KR101380448B1 (ko) * | 2005-04-21 | 2014-04-11 | 메르크 세로노 에스. 에이. | 2,3치환된 피라진 술폰아미드 |
| GB0524786D0 (en) * | 2005-12-05 | 2006-01-11 | Glaxo Group Ltd | Compounds |
| GB0526445D0 (en) * | 2005-12-23 | 2006-02-08 | Novartis Ag | Organic compounds |
| US8519135B2 (en) * | 2006-07-14 | 2013-08-27 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2/CCR9 |
| US20100234364A1 (en) * | 2006-07-14 | 2010-09-16 | Arindrajit Basak | Ccr2 inhibitors and methods of use thereof |
| EP2049515B1 (en) * | 2006-07-14 | 2011-01-26 | ChemoCentryx, Inc. | Triazolyl pyridyl benzenesulfonamides as ccr2 or ccr9 modulators for the treatment of atherosclerosis |
| US7718683B2 (en) * | 2006-07-14 | 2010-05-18 | Chemocentryx, Inc. | Triazolyl phenyl benzenesulfonamides |
| US20080076120A1 (en) * | 2006-09-14 | 2008-03-27 | Millennium Pharmaceuticals, Inc. | Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders |
| JP2010518014A (ja) * | 2007-01-31 | 2010-05-27 | バーテックス ファーマシューティカルズ インコーポレイテッド | キナーゼ阻害剤として有用な2−アミノピリジン誘導体 |
| US7776877B2 (en) * | 2007-06-22 | 2010-08-17 | Chemocentryx, Inc. | N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides |
| CA2692761C (en) * | 2007-07-12 | 2013-04-30 | Chemocentryx, Inc. | Fused heteroaryl pyridyl and phenyl benzenesulfonamides as ccr2 modulators for the treament of inflammation |
| US8586748B2 (en) * | 2008-04-09 | 2013-11-19 | Boehringer Ingelheim International Gmbh | 2-sulfonylamino-4-heteroaryl butyramide antagonists of CCR10 |
| UA103319C2 (en) | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Thiazole- and oxazole-benzene sulfonamide compounds |
| EA020460B1 (ru) | 2009-01-12 | 2014-11-28 | Пфайзер Лимитед | Производные сульфонамида |
| ES2532356T3 (es) | 2010-07-09 | 2015-03-26 | Pfizer Limited | N-sulfonilbenzamidas como inhibidores de los canales de sodio dependientes de voltaje |
| CN103201270B (zh) * | 2010-08-03 | 2015-06-24 | 日本化学医药株式会社 | P2x4受体拮抗剂 |
| RU2013132650A (ru) * | 2010-12-16 | 2015-01-27 | Аллерган, Инк. | Серные производные в качестве модуляторов хемокиновых рецепторов |
| ES2655090T3 (es) | 2010-12-16 | 2018-02-16 | Allergan, Inc. | Derivados de 1,2-bis-sulfonamida como moduladores de receptores de quimiocinas |
| CA2852160A1 (en) | 2011-10-28 | 2013-05-02 | Galderma Research & Development | New leukocyte infiltrate markers for rosacea and uses thereof |
| KR20150008891A (ko) * | 2012-05-08 | 2015-01-23 | 앤빌 엘엘씨 | 알파 7 니코틴성 아세틸콜린 수용기 알로스테릭 조절제, 그의 유도체 및 그의 용도 |
| MX2016007128A (es) | 2013-12-02 | 2016-08-11 | Chemocentryx Inc | Compuestos del receptor 6 de quimiocina (ccr6). |
| WO2017007755A1 (en) | 2015-07-06 | 2017-01-12 | Rodin Therapeutics, Inc. | Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase |
| LT3319959T (lt) | 2015-07-06 | 2021-12-27 | Alkermes, Inc. | Histono deacetilazės hetero-halogeno inhibitoriai |
| SG10202012080UA (en) | 2016-06-03 | 2021-01-28 | Chemocentryx Inc | Method of treating liver fibrosis |
| US10195188B2 (en) | 2016-06-13 | 2019-02-05 | Chemocentryx, Inc. | Method of treating pancreatic cancer |
| US10251888B2 (en) | 2016-06-13 | 2019-04-09 | Chemocentryx, Inc. | Method of treating pancreatic cancer |
| MX388165B (es) | 2016-11-23 | 2025-03-19 | Chemocentryx Inc | Método para tratar glomeruloesclerosis segmentaria focal |
| PT3562821T (pt) | 2016-12-28 | 2021-03-03 | Minoryx Therapeutics S L | Compostos de isoquinolina, métodos para a sua preparação e utilizações terapêuticas dos mesmos em condições associadas à alteração da atividade da beta-galactosidade |
| CN106854177B (zh) * | 2017-01-04 | 2019-10-11 | 苏州健雄职业技术学院 | 一种6-氯-4-羟基吡啶-3-甲醛的制备方法 |
| US10793567B2 (en) | 2017-01-11 | 2020-10-06 | Rodin Therapeutics, Inc. | Bicyclic inhibitors of histone deacetylase |
| EA039417B1 (ru) | 2017-08-07 | 2022-01-25 | Родин Терапеутикс, Инк. | Бициклические ингибиторы гистондеацетилазы |
| BR112020007183A2 (pt) | 2017-10-11 | 2020-09-24 | Chemocentryx, Inc. | tratamento de glomeruloesclerose focal segmentado com antagonistas de ccr2 |
| WO2021007386A1 (en) | 2019-07-10 | 2021-01-14 | Chemocentryx, Inc. | Indanes as pd-l1 inhibitors |
| BR112022006279A2 (pt) | 2019-10-16 | 2022-06-28 | Chemocentryx Inc | Heteroaril-bifenil aminas para o tratamento de doenças pd-l1 |
| AU2020368393B2 (en) | 2019-10-16 | 2026-01-08 | Chemocentryx, Inc. | Heteroaryl-biphenyl amides for the treatment of PD-L1 diseases |
| TW202237119A (zh) | 2020-12-10 | 2022-10-01 | 美商住友製藥腫瘤公司 | Alk﹘5抑制劑和彼之用途 |
| CN113248427B (zh) * | 2021-06-01 | 2023-05-02 | 苏州大学 | 磺酰胺基烟酸衍生物、酰胺基烟酸衍生物及其制备方法和应用 |
| WO2023031308A1 (en) * | 2021-08-31 | 2023-03-09 | Artica Therapeutics B.V. | Ccr2 inhibitors |
| NL2037411B1 (en) * | 2024-04-08 | 2025-10-31 | Univ Leiden | Protac compounds |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3901855A (en) * | 1974-08-07 | 1975-08-26 | Us Air Force | Preparation of polybenzimidazoles |
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US4403607A (en) * | 1980-05-09 | 1983-09-13 | The Regents Of The University Of California | Compatible internal bone fixation plate |
| JPS61113060A (ja) * | 1984-11-08 | 1986-05-30 | Fuji Photo Film Co Ltd | ハロゲン化銀カラ−写真感光材料 |
| ATE167473T1 (de) * | 1990-08-20 | 1998-07-15 | Eisai Co Ltd | Sulfonamid-derivate |
| JPH06135934A (ja) * | 1991-12-27 | 1994-05-17 | Ishihara Sangyo Kaisha Ltd | ピリジン誘導体又はその塩を含有するホスホリパーゼ▲a2▼阻害剤、抗炎症剤又は抗膵炎剤 |
| US5514555A (en) | 1993-03-12 | 1996-05-07 | Center For Blood Research, Inc. | Assays and therapeutic methods based on lymphocyte chemoattractants |
| US5571775A (en) * | 1994-07-11 | 1996-11-05 | Dowelanco | N-aryl[1,2,4]triazolo[1,5-a]pyridine-2-sulfonamide herbicides |
| JP3421349B2 (ja) * | 1996-02-22 | 2003-06-30 | テュラリク インコーポレイテッド | ペンタフルオロベンゼンスルホンアミドおよび類縁体 |
| US5780488A (en) * | 1996-04-03 | 1998-07-14 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| AR015104A1 (es) * | 1996-11-13 | 2001-04-18 | Dowelanco | Compuestos de n-arilsulfilimina sustituidos, utiles como catalizadores en la preparacion de compuestos de n-arilarilsulfonamida; proceso para preparar dichos compuestos y su uso para catalizar dicha preparacion. |
| GB9803228D0 (en) * | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
| EP0937711A1 (de) * | 1998-02-18 | 1999-08-25 | Roche Diagnostics GmbH | Neue Thiobenzamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel |
| JP4327915B2 (ja) * | 1998-03-30 | 2009-09-09 | 株式会社デ・ウエスタン・セラピテクス研究所 | スルフォンアミド誘導体 |
| US6380206B1 (en) * | 1998-11-23 | 2002-04-30 | Cell Pathways, Inc. | Method of inhibiting neoplastic cells with 4,5-diaminopyrimidine derivatives |
| JP2000159665A (ja) * | 1998-11-27 | 2000-06-13 | Nippon Kayaku Co Ltd | リウマチの予防または治療剤 |
| US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| CA2376781A1 (en) * | 1999-06-28 | 2001-01-04 | Janssen Pharmaceutica N.V. | Benzimidazoles and imidazopyridines as respiratory syncytial virus replication inhibitors |
| JP2001089412A (ja) * | 1999-09-22 | 2001-04-03 | Otsuka Pharmaceut Co Ltd | ベンゼン誘導体またはその医薬的に許容される塩 |
| AU2001243158A1 (en) * | 2000-02-18 | 2001-08-27 | Merck And Co., Inc. | Inhibitors of prenyl-protein transferase |
| JP2001335714A (ja) * | 2000-03-22 | 2001-12-04 | Fuji Photo Film Co Ltd | アゾ色素、その製造方法、インクジェット用インク、インクジェット記録方法 |
| US6525051B2 (en) * | 2000-03-27 | 2003-02-25 | Schering Aktiengesellschaft | N-heterocyclic derivatives as NOS inhibitors |
| JP2002036052A (ja) * | 2000-07-25 | 2002-02-05 | Sankyo Mfg Co Ltd | 自動工具交換装置 |
| US7468253B2 (en) | 2001-06-07 | 2008-12-23 | Chemocentryx, Inc. | Method for multiple chemokine receptor screening for antagonists using RAM assay |
| DE60216606T2 (de) | 2001-06-07 | 2007-04-05 | Chemocentryx Inc., Mountain View | Zellwanderungsassay |
| EP1453516A2 (de) * | 2001-10-17 | 2004-09-08 | Boehringer Ingelheim Pharma GmbH & Co.KG | 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren |
| ATE312096T1 (de) * | 2001-12-18 | 2005-12-15 | Neue verbindungen | |
| AU2003220401A1 (en) * | 2002-03-18 | 2003-10-08 | Bristol-Myers Squibb Company | Uracil derivatives as inhibitors of tnf-alpha converting enzyme (tace) and matrix metalloproteinases |
| EP1507756B1 (en) * | 2002-05-24 | 2015-07-22 | Millennium Pharmaceuticals, Inc. | Ccr9 inhibitors and methods of use thereof |
| US20070021466A1 (en) * | 2002-11-18 | 2007-01-25 | Solomon Ungashe | CCR2 inhibitors and methods of use thereof |
| DK1798223T4 (da) * | 2002-11-18 | 2014-09-22 | Chemocentryx Inc | Arylsulfonamider |
| WO2004056774A2 (en) * | 2002-12-19 | 2004-07-08 | Neurogen Corporation | Substituted biphenyl-4-carboxylic acid arylamide analogues as capsaicin receptor modulators |
| WO2004058265A1 (en) * | 2002-12-24 | 2004-07-15 | Biofocus Plc | Compound libraries of 2,3-substituted pyrazine derivatives capable of binding to g-protein coupled receptors |
| CA2526385C (en) * | 2003-05-29 | 2008-07-22 | Abbott Laboratories | Continuous dosing regimen with abt-751 |
| EP1643960A2 (en) * | 2003-07-02 | 2006-04-12 | Merck & Co., Inc. | Arylsulfonamide derivatives |
| US7622583B2 (en) * | 2005-01-14 | 2009-11-24 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2 |
| US9715915B2 (en) | 2014-10-30 | 2017-07-25 | Samsung Electronics Co., Ltd. | Magneto-resistive devices including a free layer having different magnetic properties during operations |
-
2006
- 2006-01-13 DK DK11002389.2T patent/DK2354126T3/da active
- 2006-01-13 WO PCT/US2006/001341 patent/WO2006076644A2/en not_active Ceased
- 2006-01-13 CA CA2594726A patent/CA2594726C/en not_active Expired - Lifetime
- 2006-01-13 DE DE602006020979T patent/DE602006020979D1/de not_active Expired - Lifetime
- 2006-01-13 EP EP06718419A patent/EP1838674B9/en not_active Expired - Lifetime
- 2006-01-13 DK DK06718419.2T patent/DK1838674T3/da active
- 2006-01-13 US US11/332,786 patent/US20060173019A1/en not_active Abandoned
- 2006-01-13 PL PL11002389T patent/PL2354126T3/pl unknown
- 2006-01-13 ES ES11002389.2T patent/ES2440965T3/es not_active Expired - Lifetime
- 2006-01-13 MX MX2007008474A patent/MX2007008474A/es active IP Right Grant
- 2006-01-13 EP EP11002389.2A patent/EP2354126B1/en not_active Expired - Lifetime
- 2006-01-13 PL PL06718419T patent/PL1838674T3/pl unknown
- 2006-01-13 EP EP12162572A patent/EP2474532A1/en not_active Withdrawn
- 2006-01-13 JP JP2007551428A patent/JP5253815B2/ja not_active Expired - Lifetime
- 2006-01-13 AU AU2006204750A patent/AU2006204750C1/en not_active Expired
- 2006-01-13 AT AT06718419T patent/ATE503741T1/de active
-
2007
- 2007-07-11 IL IL184539A patent/IL184539A/en active IP Right Grant
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