JP2005504789A5 - - Google Patents
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- JP2005504789A5 JP2005504789A5 JP2003526403A JP2003526403A JP2005504789A5 JP 2005504789 A5 JP2005504789 A5 JP 2005504789A5 JP 2003526403 A JP2003526403 A JP 2003526403A JP 2003526403 A JP2003526403 A JP 2003526403A JP 2005504789 A5 JP2005504789 A5 JP 2005504789A5
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- JP
- Japan
- Prior art keywords
- substituted
- group
- alkyl
- unsubstituted
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 CC1C(C)=C(*)N(C)[C@@]1C=CC=C Chemical compound CC1C(C)=C(*)N(C)[C@@]1C=CC=C 0.000 description 6
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32210501P | 2001-09-13 | 2001-09-13 | |
| PCT/US2002/027514 WO2003022274A2 (en) | 2001-09-13 | 2002-08-28 | 2-aroylimidazole compounds for treating cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005504789A JP2005504789A (ja) | 2005-02-17 |
| JP2005504789A5 true JP2005504789A5 (enExample) | 2006-01-05 |
Family
ID=23253436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003526403A Pending JP2005504789A (ja) | 2001-09-13 | 2002-08-28 | 癌治療のための２−アロイルイミダゾール化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6743919B2 (enExample) |
| EP (1) | EP1427413A2 (enExample) |
| JP (1) | JP2005504789A (enExample) |
| AU (1) | AU2002323475B2 (enExample) |
| CA (1) | CA2460345A1 (enExample) |
| WO (1) | WO2003022274A2 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2460345A1 (en) * | 2001-09-13 | 2003-03-20 | Synta Pharmaceuticals Corp. | 2-aroylimidazole compounds for treating cancer |
| WO2003068742A1 (en) * | 2002-02-12 | 2003-08-21 | Wisconsin Alumni Research Foundation | Synthesis of indole thiazole compounds as ligands for the ah receptor |
| TW200503738A (en) * | 2003-07-16 | 2005-02-01 | Tzu Chi Buddhist General Hospital | Method for extracting antineoplastic components from bupleurum scorzonerifolium |
| AU2004284420A1 (en) * | 2003-09-24 | 2005-05-06 | Vertex Pharmaceuticals Incorporated | 4-azole substituted imidazole compositions useful as inhibitors or c-Met receptor tyrosine kinase |
| KR101167335B1 (ko) * | 2003-10-31 | 2012-07-19 | 오클랜드 유니서비시즈 리미티드 | 니트로페닐 머스타드, 니트로페닐아지리딘 알코올 및 이에상응하는 포스페이트, 및 타겟화된 세포독성제로서의이들의 용도 |
| GB0403781D0 (en) * | 2004-02-20 | 2004-03-24 | Astrazeneca Ab | Chemical compounds |
| AU2005286846A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as therapeutic agents |
| US7951805B2 (en) | 2004-09-20 | 2011-05-31 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase |
| WO2006101521A2 (en) | 2004-09-20 | 2006-09-28 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
| EP2316458A1 (en) | 2004-09-20 | 2011-05-04 | Xenon Pharmaceuticals Inc. | Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase |
| US8071603B2 (en) | 2004-09-20 | 2011-12-06 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| AU2005286647A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| AR051026A1 (es) | 2004-09-20 | 2006-12-13 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa |
| WO2006128129A2 (en) * | 2005-05-26 | 2006-11-30 | Synta Pharmaceuticals Corp. | Method for treating cancer |
| JP2009513563A (ja) | 2005-06-03 | 2009-04-02 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | ヒトのステアロイル−ＣｏＡデサチュラーゼ阻害剤としてのアミノチアゾール誘導体 |
| US20100256046A1 (en) * | 2009-04-03 | 2010-10-07 | Tetralogic Pharmaceuticals Corporation | Treatment of proliferative disorders |
| US20070042428A1 (en) * | 2005-08-09 | 2007-02-22 | Stacy Springs | Treatment of proliferative disorders |
| AU2006318212C1 (en) * | 2005-11-23 | 2012-08-30 | The Board Of Regents Of The University Of Texas System | Oncogenic ras-specific cytotoxic compound and methods of use thereof |
| EP1998766A2 (en) * | 2005-12-16 | 2008-12-10 | Ironwood Pharmaceuticals, Inc. | Useful indole compounds |
| US7649098B2 (en) * | 2006-02-24 | 2010-01-19 | Lexicon Pharmaceuticals, Inc. | Imidazole-based compounds, compositions comprising them and methods of their use |
| WO2008005908A2 (en) | 2006-07-07 | 2008-01-10 | Forest Laboratories Holdings Limited | Pyridoimidazole derivatives |
| EP2120938A4 (en) * | 2006-12-20 | 2010-12-08 | Merck Sharp & Dohme | IMIDAZOPYRIDINE ANALOGUE AS CB2 RECEPTOR MODULATORS FOR THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES |
| TW200920355A (en) * | 2007-09-06 | 2009-05-16 | Lexicon Pharmaceuticals Inc | Compositions and methods for treating immunological and inflammatory diseases and disorders |
| WO2009053716A1 (en) * | 2007-10-26 | 2009-04-30 | F.Hoffmann-La Roche Ag | Purine derivatives useful as pi3 kinase inhibitors |
| EP2279188B1 (en) | 2008-05-30 | 2015-01-28 | Genentech, Inc. | Purine pi3k inhibitor compounds and methods of use |
| US8513221B2 (en) | 2008-07-07 | 2013-08-20 | Xcovery Holding, LLC | PI3K isoform selective inhibitors |
| WO2010138589A1 (en) | 2009-05-27 | 2010-12-02 | Genentech, Inc. | Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use |
| EP2560640A1 (en) | 2010-04-19 | 2013-02-27 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of a hsp90 inhibitory compounds and a egfr inhibitor |
| KR101531117B1 (ko) | 2010-07-14 | 2015-06-23 | 에프. 호프만-라 로슈 아게 | Pi3k p110 델타에 대해 선택적인 퓨린 화합물, 및 사용 방법 |
| CN103201262B (zh) | 2010-08-20 | 2016-06-01 | 艾米拉医药股份有限公司 | 自分泌运动因子抑制剂及其用途 |
| BR112013014914B8 (pt) | 2010-12-16 | 2020-08-04 | Hoffmann La Roche | composto, composição farmacêutica e uso de um composto |
| EP2714680B1 (en) | 2011-05-27 | 2015-11-25 | Amira Pharmaceuticals, Inc. | Heterocyclic autotaxin inhibitors and uses thereof |
| JP2014534228A (ja) | 2011-11-02 | 2014-12-18 | シンタ ファーマシューティカルズ コーポレーション | 白金含有剤とｈｓｐ９０阻害剤の組合せ療法 |
| WO2013067162A1 (en) | 2011-11-02 | 2013-05-10 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of hsp90 inhibitors with topoisomerase i inhibitors |
| CA2854188A1 (en) | 2011-11-14 | 2013-05-23 | Synta Pharmaceuticals Corp. | Combination therapy of hsp90 inhibitors with braf inhibitors |
| CN108841778B (zh) * | 2018-04-28 | 2022-05-17 | 大连普瑞康生物技术有限公司 | 一种红豆杉细胞组织培养物 |
| WO2022031736A1 (en) | 2020-08-04 | 2022-02-10 | Nura Bio, Inc. | Substituted pyridine derivatives as sarm1 inhibitors |
| EP4214197A1 (en) | 2020-09-16 | 2023-07-26 | Nura Bio, Inc. | Substituted pyridine derivatives as sarm1 inhibitors |
| KR20240041987A (ko) | 2021-07-28 | 2024-04-01 | 누라 바이오, 인크. | Sarm1 억제제로서 치환된 피리딘 유도체 |
| US20240417399A1 (en) * | 2021-10-14 | 2024-12-19 | Galileo Biosystems, Inc. | Aryl hydrocarbon receptor (ahr) modulators and therapeutic uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0272810A3 (en) * | 1986-11-26 | 1988-07-20 | Harbor Branch Oceanographic Institution, Inc. | Antitumor and antiviral alkaloids |
| US4866084A (en) * | 1987-07-17 | 1989-09-12 | Harbor Branch Oceanographic Institution, Inc. | Topsentin compounds effective against viruses and certain tumors |
| US5290777A (en) * | 1993-02-24 | 1994-03-01 | Regents Of The Univ. Of California | Use for topsentin compounds and pharmaceutical compositions containing same |
| US6548530B1 (en) * | 1995-10-03 | 2003-04-15 | The Scripps Research Institute | CBI analogs of CC-1065 and the duocarmycins |
| JP2001503414A (ja) | 1996-10-31 | 2001-03-13 | ハーバー ブランチ オーシャノグラフィック インスティテューション インク． | 抗神経性炎症化合物および組成物ならびにその使用法 |
| US6291501B1 (en) | 1998-02-20 | 2001-09-18 | Harbor Branch Oceanographic Institution, Inc. | Compounds and methods of use for treatment of neurogenic inflammation |
| CA2335254A1 (en) | 1998-07-08 | 2000-01-20 | Harbor Branch Oceanographic Institution, Inc. | Bis-indole derivatives and their use as antiinflammatory agents |
| CZ20014126A3 (cs) * | 1999-05-21 | 2002-03-13 | Scios Inc. | Indolové deriváty jako inhibitory p38 kinasy |
| CA2460345A1 (en) * | 2001-09-13 | 2003-03-20 | Synta Pharmaceuticals Corp. | 2-aroylimidazole compounds for treating cancer |
-
2002
- 2002-08-28 CA CA002460345A patent/CA2460345A1/en not_active Abandoned
- 2002-08-28 JP JP2003526403A patent/JP2005504789A/ja active Pending
- 2002-08-28 EP EP02757458A patent/EP1427413A2/en not_active Withdrawn
- 2002-08-28 AU AU2002323475A patent/AU2002323475B2/en not_active Ceased
- 2002-08-28 WO PCT/US2002/027514 patent/WO2003022274A2/en not_active Ceased
- 2002-08-29 US US10/233,371 patent/US6743919B2/en not_active Expired - Fee Related
-
2004
- 2004-03-16 US US10/802,292 patent/US7081466B2/en not_active Expired - Fee Related
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