JP2006508147A5 - - Google Patents
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- Publication number
- JP2006508147A5 JP2006508147A5 JP2004553999A JP2004553999A JP2006508147A5 JP 2006508147 A5 JP2006508147 A5 JP 2006508147A5 JP 2004553999 A JP2004553999 A JP 2004553999A JP 2004553999 A JP2004553999 A JP 2004553999A JP 2006508147 A5 JP2006508147 A5 JP 2006508147A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- compound
- formula
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42728302P | 2002-11-18 | 2002-11-18 | |
| US10/622,854 US20040209942A1 (en) | 2002-07-17 | 2003-07-17 | Activated checkpoint therapy and methods of use thereof |
| PCT/US2003/022631 WO2004007531A2 (en) | 2002-07-17 | 2003-07-17 | Activated checkpoint therapy and methods of use thereof |
| PCT/US2003/037219 WO2004045557A2 (en) | 2002-11-18 | 2003-11-18 | Novel lapachone compounds and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006508147A JP2006508147A (ja) | 2006-03-09 |
| JP2006508147A5 true JP2006508147A5 (enExample) | 2007-01-18 |
Family
ID=34375156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004553999A Pending JP2006508147A (ja) | 2002-11-18 | 2003-11-18 | 新規ラパコン化合物およびその使用方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20040266857A1 (enExample) |
| EP (1) | EP1567515A4 (enExample) |
| JP (1) | JP2006508147A (enExample) |
| CN (1) | CN1729183A (enExample) |
| AR (1) | AR056613A1 (enExample) |
| AU (1) | AU2003295738A1 (enExample) |
| BR (1) | BR0316296A (enExample) |
| CA (1) | CA2506340A1 (enExample) |
| EA (1) | EA200500849A1 (enExample) |
| MX (1) | MXPA05005314A (enExample) |
| TW (1) | TW200510367A (enExample) |
| WO (1) | WO2004045557A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7361691B2 (en) | 2002-12-02 | 2008-04-22 | Arqule, Inc. | Method of treating cancers using β-lapachone or analogs or derivatives thereof |
| CA2546445A1 (en) | 2003-11-26 | 2005-06-16 | Arqule, Inc. | Use of beta-lapachone for protecting against radiation injury |
| WO2005082353A2 (en) * | 2004-02-20 | 2005-09-09 | Arqule, Inc. | Use of beta-lapachone for treating or preventing cancer |
| US20050187288A1 (en) * | 2004-02-20 | 2005-08-25 | Chiang Li | Beta-lapachone and methods of treating cancer |
| WO2005082357A1 (en) * | 2004-02-20 | 2005-09-09 | Arqule, Inc. | Use of beta-lapachone for treating hematologic tumors |
| EP2033638A2 (en) | 2004-02-20 | 2009-03-11 | Arqule, Inc. | Beta-lapachone for the treatment of pancreatic cancer |
| WO2005082358A2 (en) * | 2004-02-20 | 2005-09-09 | Arqule, Inc. | Use of beta-lapachone as a broad spectrum anti-cancer agent |
| CA2556823A1 (en) | 2004-02-20 | 2005-09-09 | Arqule, Inc. | Use of beta-lapachone for the treatment of lung cancer |
| EP1732539A2 (en) * | 2004-02-20 | 2006-12-20 | Arqule, Inc. | Use of beta-lapachone for the treatment of colon cancer |
| US8614228B2 (en) | 2004-08-11 | 2013-12-24 | Arqule, Inc. | Quinone prodrug compositions and methods of use |
| WO2006020722A2 (en) * | 2004-08-11 | 2006-02-23 | Arqule, Inc. | Polymer conjugates of beta-lapachone and beta-lapachone analogs for tumor targeting |
| US20060204981A1 (en) | 2005-01-07 | 2006-09-14 | Chiang Li | Compositions for modulation of PARP and methods for screening for same |
| WO2006128120A2 (en) * | 2005-05-26 | 2006-11-30 | Arqule, Inc. | Novel lapachone compounds and methods of use thereof |
| WO2007139569A1 (en) * | 2006-05-26 | 2007-12-06 | Arqule, Inc. | Novel lapachone compounds and methods of use thereof |
| TW200824692A (en) | 2006-08-21 | 2008-06-16 | Arqule Inc | Novel lapachone compounds and methods of use thereof |
| WO2008115804A1 (en) * | 2007-03-16 | 2008-09-25 | Lankenau Institute For Medical Research | Novel ido inhibitors and methods of use thereof |
| KR20100017483A (ko) | 2007-04-30 | 2010-02-16 | 아르퀼 인코포레이티드 | 퀴논 화합물의 하이드록시 설포네이트 및 그 용도 |
| WO2009051752A1 (en) * | 2007-10-16 | 2009-04-23 | Arqule, Inc. | Novel lapachone compounds and methods of use thereof |
| KR101405823B1 (ko) | 2007-12-24 | 2014-06-12 | 주식회사 케이티앤지생명과학 | 녹내장의 치료 및 예방을 위한 약제 조성물 |
| KR20090071829A (ko) * | 2007-12-28 | 2009-07-02 | 주식회사 머젠스 | 신장질환의 치료 및 예방을 위한 약제 조성물 |
| KR20090073381A (ko) * | 2007-12-31 | 2009-07-03 | 주식회사 머젠스 | 심장질환의 치료 및 예방을 위한 약제 조성물 |
| BR112012030745A2 (pt) * | 2010-06-01 | 2016-08-23 | Belle Aire Fragrances Inc | produto de higiene bucal ou nasal e seu método de fabricação |
| US10829427B2 (en) | 2015-12-18 | 2020-11-10 | The Board Of Regents Of The University Of Texas System | Naphthoquinones, pro-drugs, and methods of use thereof |
| KR101735275B1 (ko) * | 2016-12-20 | 2017-05-16 | 아주대학교산학협력단 | 베타-라파촌을 포함하는 수면 장애 예방 또는 치료용 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2011455B (en) * | 1977-12-21 | 1982-03-03 | Ici Ltd | Chemical process |
| US5346917A (en) * | 1991-06-10 | 1994-09-13 | Sterling Winthrop Inc. | Thioxanthenone antitumor agents |
| US5763625A (en) * | 1995-04-25 | 1998-06-09 | Wisconsin Alumni Research Foundation | Synthesis and use of β-lapachone analogs |
| US6245807B1 (en) * | 1995-08-24 | 2001-06-12 | Dana-Farber Cancer Institute | Treatment of human prostate disease |
| US5824700A (en) * | 1996-02-20 | 1998-10-20 | Wisconsin Alumni Research Foundation | Ortho-quinone derivatives novel synthesis therefor and their use in the inhibition of neoplastic cell growth |
| US5883270A (en) * | 1996-02-20 | 1999-03-16 | Wisconsin Alumni Research Foundation | 4-substituted-1, 2-naphthoquinones and their use in the inhibition of neoplastic cell growth |
| EP1181013B1 (en) * | 1999-04-14 | 2006-10-11 | Dana-Farber Cancer Institute, Inc. | Method and composition for the treatment of cancer |
| CA2492772A1 (en) * | 2002-07-17 | 2004-01-22 | Chiang J. Li | Activated checkpoint therapy and methods of use thereof |
-
2003
- 2003-11-18 AR ARP030104253A patent/AR056613A1/es not_active Application Discontinuation
- 2003-11-18 CA CA002506340A patent/CA2506340A1/en not_active Abandoned
- 2003-11-18 TW TW092132328A patent/TW200510367A/zh unknown
- 2003-11-18 CN CNA2003801066171A patent/CN1729183A/zh active Pending
- 2003-11-18 BR BR0316296-6A patent/BR0316296A/pt not_active Application Discontinuation
- 2003-11-18 WO PCT/US2003/037219 patent/WO2004045557A2/en not_active Ceased
- 2003-11-18 AU AU2003295738A patent/AU2003295738A1/en not_active Abandoned
- 2003-11-18 MX MXPA05005314A patent/MXPA05005314A/es not_active Application Discontinuation
- 2003-11-18 EA EA200500849A patent/EA200500849A1/ru unknown
- 2003-11-18 JP JP2004553999A patent/JP2006508147A/ja active Pending
- 2003-11-18 EP EP03786941A patent/EP1567515A4/en active Pending
-
2004
- 2004-03-26 US US10/810,260 patent/US20040266857A1/en not_active Abandoned
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