JP2015508823A5 - - Google Patents

Download PDF

Info

Publication number
JP2015508823A5
JP2015508823A5 JP2014560041A JP2014560041A JP2015508823A5 JP 2015508823 A5 JP2015508823 A5 JP 2015508823A5 JP 2014560041 A JP2014560041 A JP 2014560041A JP 2014560041 A JP2014560041 A JP 2014560041A JP 2015508823 A5 JP2015508823 A5 JP 2015508823A5
Authority
JP
Japan
Prior art keywords
substituted
unsubstituted
alkyl
alkoxy
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014560041A
Other languages
English (en)
Japanese (ja)
Other versions
JP6249966B2 (ja
JP2015508823A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/028328 external-priority patent/WO2013130811A1/en
Publication of JP2015508823A publication Critical patent/JP2015508823A/ja
Publication of JP2015508823A5 publication Critical patent/JP2015508823A5/ja
Application granted granted Critical
Publication of JP6249966B2 publication Critical patent/JP6249966B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014560041A 2012-02-29 2013-02-28 アザ−アリール1h−ピラゾール−1−イルベンゼンスルホンアミド Active JP6249966B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261604998P 2012-02-29 2012-02-29
US61/604,998 2012-02-29
PCT/US2013/028328 WO2013130811A1 (en) 2012-02-29 2013-02-28 Pyrazol-1-yl benzene sulfonamides as ccr9 antagonists

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017152743A Division JP6322325B2 (ja) 2012-02-29 2017-08-07 Cc9アンタゴニストとしてのピラゾール−1−イルベンゼンスルホンアミド

Publications (3)

Publication Number Publication Date
JP2015508823A JP2015508823A (ja) 2015-03-23
JP2015508823A5 true JP2015508823A5 (enExample) 2016-09-01
JP6249966B2 JP6249966B2 (ja) 2017-12-20

Family

ID=47844528

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2014560041A Active JP6249966B2 (ja) 2012-02-29 2013-02-28 アザ−アリール1h−ピラゾール−1−イルベンゼンスルホンアミド
JP2017152743A Active JP6322325B2 (ja) 2012-02-29 2017-08-07 Cc9アンタゴニストとしてのピラゾール−1−イルベンゼンスルホンアミド
JP2018070806A Active JP6553236B2 (ja) 2012-02-29 2018-04-02 Cc9アンタゴニストとしてのピラゾール−1−イルベンゼンスルホンアミド

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017152743A Active JP6322325B2 (ja) 2012-02-29 2017-08-07 Cc9アンタゴニストとしてのピラゾール−1−イルベンゼンスルホンアミド
JP2018070806A Active JP6553236B2 (ja) 2012-02-29 2018-04-02 Cc9アンタゴニストとしてのピラゾール−1−イルベンゼンスルホンアミド

Country Status (18)

Country Link
US (5) US8916601B2 (enExample)
EP (3) EP3738958A1 (enExample)
JP (3) JP6249966B2 (enExample)
KR (1) KR102083693B1 (enExample)
CN (2) CN104520288B (enExample)
AU (3) AU2013225938B2 (enExample)
BR (1) BR112014021148B1 (enExample)
CA (1) CA2865714C (enExample)
DK (2) DK2820006T3 (enExample)
ES (2) ES2645617T3 (enExample)
HK (1) HK1206012A1 (enExample)
MX (2) MX372722B (enExample)
PL (2) PL2820006T3 (enExample)
PT (1) PT3263564T (enExample)
RU (1) RU2627268C2 (enExample)
SG (2) SG11201405241VA (enExample)
WO (1) WO2013130811A1 (enExample)
ZA (1) ZA201406432B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10827315B2 (en) * 2006-04-07 2020-11-03 Groupon, Inc. Facilitating user interactions based on proximity
US9100454B2 (en) 2006-04-07 2015-08-04 Groupon, Inc. Method and system for enabling the creation and maintenance of proximity-related user groups
DK2820006T3 (da) * 2012-02-29 2017-11-06 Chemocentryx Inc Pyrazol-1-yl benzen sulfonamider som ccr9 antagonister
UY35165A (es) 2012-12-04 2014-06-30 Takeda Pharmaceutical Método profiláctico o terapéutico para el síndrome de sjogren
GB201308978D0 (en) 2013-05-17 2013-07-03 Imp Innovations Ltd Method for producing polymers and block copolymers
CN105960237B (zh) * 2013-12-02 2020-03-31 凯莫森特里克斯股份有限公司 Ccr6化合物
JP2017501145A (ja) * 2013-12-23 2017-01-12 ノージン ビーブイ Ccr9調節因子として有用な化合物
MA40592A (fr) 2014-10-06 2016-04-14 Chemocentryx Inc Compositions et méthodes pour le traitement d'une maladie inflammatoire de l'intestin à l'aide d'une polythérapie à base d'inhibiteurs à petites molécules de récepteur 9 de chimiokine c-c (ccr9) et d'anticorps bloquants anti-intégrine alpha4beta7
GB201515350D0 (en) 2015-08-28 2015-10-14 Econic Technologies Ltd Method for preparing polyols
BR112018014666B1 (pt) * 2016-01-20 2024-01-02 Chemocentryx, Inc Compostos de 2-oxindol, seu uso e composição farmacêutica
RU2768479C2 (ru) * 2016-06-13 2022-03-24 Хемоцентрикс, Инк. Способы лечения рака поджелудочной железы
CN110636846B (zh) * 2017-05-17 2023-05-16 艾库斯生物科学有限公司 用于治疗癌症相关疾病的喹唑啉吡唑衍生物
AU2019312296B2 (en) * 2018-07-27 2025-05-29 Arcus Biosciences, Inc. Pyridone A2R antagonists
US20240281033A1 (en) * 2018-10-24 2024-08-22 Screen Skinz, Inc. Screen protector with engraved image
US20200319677A1 (en) * 2018-10-24 2020-10-08 Clay Canning Screen protector with engraved image
KR102890201B1 (ko) 2019-07-10 2025-11-24 케모센트릭스, 인크. Pd-l1 억제제로서의 인단
EP3805206B1 (en) * 2019-10-08 2026-08-05 Novaled GmbH Compound and an organic semiconducting layer, an organic electronic device, a display device and a lighting device comprising the same
ES3068390T3 (en) * 2019-10-16 2026-05-29 Chemocentryx Inc Heteroaryl-biphenyl amides for the treatment of pd-l1 diseases
AU2020368392B2 (en) 2019-10-16 2026-01-08 Chemocentryx, Inc. Heteroaryl-biphenyl amines for the treatment of PD-L1 diseases
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
TWI904146B (zh) * 2020-03-31 2025-11-11 美商卡默森屈有限公司 使用ccr9抑制劑及抗il-23阻斷抗體治療發炎性腸道疾病的組成物及方法
SMT202500447T1 (it) 2021-11-02 2026-01-12 Flare Therapeutics Inc Agonisti inversi di pparg e loro usi
KR102584607B1 (ko) 2023-01-19 2023-10-04 아주대학교산학협력단 1h-피라졸-3-아마이드계 화합물 유도체를 포함하는 염증성 피부질환 예방 또는 치료용 조성물

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US5120643A (en) 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US6159686A (en) 1992-09-14 2000-12-12 Sri International Up-converting reporters for biological and other assays
US5514555A (en) 1993-03-12 1996-05-07 Center For Blood Research, Inc. Assays and therapeutic methods based on lymphocyte chemoattractants
US6322901B1 (en) 1997-11-13 2001-11-27 Massachusetts Institute Of Technology Highly luminescent color-selective nano-crystalline materials
US6207392B1 (en) 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
US5990479A (en) 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6326144B1 (en) 1998-09-18 2001-12-04 Massachusetts Institute Of Technology Biological applications of quantum dots
US6306610B1 (en) 1998-09-18 2001-10-23 Massachusetts Institute Of Technology Biological applications of quantum dots
US6251303B1 (en) 1998-09-18 2001-06-26 Massachusetts Institute Of Technology Water-soluble fluorescent nanocrystals
US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
AU2001273040A1 (en) 2000-06-27 2002-01-08 Du Pont Pharmaceuticals Company Factor xa inhibitors
AU2003248549B2 (en) * 2002-05-24 2010-04-08 Millennium Pharmaceuticals, Inc. CCR9 inhibitors and methods of use thereof
AU2003298661B2 (en) * 2002-11-18 2007-05-10 Chemocentryx, Inc. Aryl sulfonamides
TW200510311A (en) * 2002-12-23 2005-03-16 Millennium Pharm Inc CCr8 inhibitors
SE0301653D0 (sv) * 2003-06-05 2003-06-05 Astrazeneca Ab Novel compounds
JP2007537275A (ja) * 2004-05-12 2007-12-20 ケモセントリックス, インコーポレイテッド アリールスルホンアミド
SE0402635D0 (sv) 2004-10-29 2004-10-29 Astrazeneca Ab Chemical compounds
PL2046762T3 (pl) * 2006-07-14 2011-07-29 Chemocentryx Inc Triazolilofenylobenzenosulfonamidy
US20100234364A1 (en) * 2006-07-14 2010-09-16 Arindrajit Basak Ccr2 inhibitors and methods of use thereof
MX2009008425A (es) 2007-02-06 2009-08-17 Novartis Ag Derivados de 1-bencensulfonil-1h-indol como inhibidores de la actividad de ccr9.
US7776877B2 (en) * 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
US9315449B2 (en) 2008-05-15 2016-04-19 Duke University Substituted pyrazoles as heat shock transcription factor activators
DK2820006T3 (da) * 2012-02-29 2017-11-06 Chemocentryx Inc Pyrazol-1-yl benzen sulfonamider som ccr9 antagonister
MA40592A (fr) * 2014-10-06 2016-04-14 Chemocentryx Inc Compositions et méthodes pour le traitement d'une maladie inflammatoire de l'intestin à l'aide d'une polythérapie à base d'inhibiteurs à petites molécules de récepteur 9 de chimiokine c-c (ccr9) et d'anticorps bloquants anti-intégrine alpha4beta7
US9715915B2 (en) 2014-10-30 2017-07-25 Samsung Electronics Co., Ltd. Magneto-resistive devices including a free layer having different magnetic properties during operations

Similar Documents

Publication Publication Date Title
RU2014136216A (ru) Аза-арил-1Н-пиразол-1-ил-сульфонамиды
JP2014517017A5 (ja) 化合物、その医薬組成物、及び癌治療用の阻害薬としてのその使用
RU2017134013A (ru) Производные желчных кислот в качестве агонистов fxr/tgr5 и способы их применения
RU2017115809A (ru) Комбинированная терапия ингибиторами с-с хемокинового рецептора 9 (ccr9) и антителами, блокирующими альфа4бета7-интегрин
JP2016525075A5 (enExample)
RU2014114466A (ru) ИНДАЗОЛ-3-КАРБОКСАМИДЫ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ СИГНАЛЬНОГО ПУТИ WNT/β-КАТЕНИНА
CN109311812A (zh) 作为c-MET抑制剂的吡啶酮类化合物
JP2016540051A5 (enExample)
JP2017511357A5 (enExample)
JP2016535784A5 (enExample)
JP2017514855A5 (enExample)
JP2009511490A5 (enExample)
JP2008504304A5 (enExample)
JP2015503622A5 (enExample)
JP2008504301A5 (enExample)
JP2016506368A5 (enExample)
JP2017509689A5 (enExample)
JP2016531113A5 (enExample)
JP2017501236A5 (enExample)
RU2020112502A (ru) Циклические динуклеотиды в качестве стимулятора модуляторов генов интерферона
JP2014507464A5 (enExample)
JP2016535732A5 (enExample)
JP2016501246A5 (enExample)
RU2017104856A (ru) Функционализированные и замещенные индолы в качестве противораковых средств
JP2010501478A5 (enExample)