JP2008524335A - イミダゾ［４，５−ｃ］ピリジン化合物および抗ウイルス処置法 - Google Patents

イミダゾ［４，５−ｃ］ピリジン化合物および抗ウイルス処置法 Download PDF

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Publication number
JP2008524335A
JP2008524335A JP2007548448A JP2007548448A JP2008524335A JP 2008524335 A JP2008524335 A JP 2008524335A JP 2007548448 A JP2007548448 A JP 2007548448A JP 2007548448 A JP2007548448 A JP 2007548448A JP 2008524335 A JP2008524335 A JP 2008524335A
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Prior art keywords
acid
compound
compounds
imidazo
salts
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JP2008524335A5 (US20070167479A1-20070719-C00034.png
Inventor
ボンディ，スティーブン・エス
オール，デービッド・エイ
ツェ，ウィンストン・シィ
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ギリアド サイエンシズ， インコーポレイテッド
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Publication of JP2008524335A publication Critical patent/JP2008524335A/ja
Publication of JP2008524335A5 publication Critical patent/JP2008524335A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2007548448A 2004-12-21 2005-12-21 イミダゾ［４，５−ｃ］ピリジン化合物および抗ウイルス処置法 Withdrawn JP2008524335A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63821504P 2004-12-21 2004-12-21
PCT/US2005/046477 WO2006069193A2 (en) 2004-12-21 2005-12-21 Imidazo[4,5-c]pyridine compound and method of antiviral treatment

Related Child Applications (1)

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JP2012148683A Division JP2012184265A (ja) 2004-12-21 2012-07-02 イミダゾ［４，５−ｃ］ピリジン化合物および抗ウイルス処置法

Publications (2)

Publication Number Publication Date
JP2008524335A true JP2008524335A (ja) 2008-07-10
JP2008524335A5 JP2008524335A5 (US20070167479A1-20070719-C00034.png) 2009-02-19

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JP2007548448A Withdrawn JP2008524335A (ja) 2004-12-21 2005-12-21 イミダゾ［４，５−ｃ］ピリジン化合物および抗ウイルス処置法
JP2012148683A Pending JP2012184265A (ja) 2004-12-21 2012-07-02 イミダゾ［４，５−ｃ］ピリジン化合物および抗ウイルス処置法

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Country Status (16)

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US (2) US20060252791A1 (US20070167479A1-20070719-C00034.png)
EP (1) EP1841765B1 (US20070167479A1-20070719-C00034.png)
JP (2) JP2008524335A (US20070167479A1-20070719-C00034.png)
AT (1) ATE426601T1 (US20070167479A1-20070719-C00034.png)
AU (1) AU2005319167B2 (US20070167479A1-20070719-C00034.png)
CA (1) CA2592388C (US20070167479A1-20070719-C00034.png)
CY (1) CY1109087T1 (US20070167479A1-20070719-C00034.png)
DE (1) DE602005013580D1 (US20070167479A1-20070719-C00034.png)
DK (1) DK1841765T5 (US20070167479A1-20070719-C00034.png)
ES (1) ES2324794T3 (US20070167479A1-20070719-C00034.png)
HK (1) HK1113570A1 (US20070167479A1-20070719-C00034.png)
NZ (1) NZ556624A (US20070167479A1-20070719-C00034.png)
PL (1) PL1841765T3 (US20070167479A1-20070719-C00034.png)
PT (1) PT1841765E (US20070167479A1-20070719-C00034.png)
SI (1) SI1841765T1 (US20070167479A1-20070719-C00034.png)
WO (1) WO2006069193A2 (US20070167479A1-20070719-C00034.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
EP1706403B9 (en) * 2003-12-22 2012-07-25 K.U.Leuven Research & Development Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
MX2009000235A (es) * 2006-07-07 2009-01-23 Gilead Sciences Inc Compuesto de piridazina novedoso y uso del mismo.
JP5639762B2 (ja) * 2006-12-14 2014-12-10 ギリアード サイエンシーズ， インコーポレイテッド ウイルス阻害剤
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
WO2009011787A1 (en) * 2007-07-13 2009-01-22 Genelabs Technologies, Inc. Anti-viral compounds, compositions, and methods of use
JP2013526581A (ja) 2010-05-21 2013-06-24 ギリアード サイエンシーズ， インコーポレイテッド ヘテロ環式フラビウイルス科ウイルス阻害剤
ES2892123T3 (es) 2014-12-26 2022-02-02 Univ Emory Derivados antivíricos de N4-hidroxicitidina
GB2581936B (en) 2017-12-07 2021-02-10 Univ Emory N4-hydroxycytidine and derivatives and anti-viral uses related thereto

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007518720A (ja) * 2003-12-22 2007-07-12 カー・イュー・ルーベン・リサーチ・アンド・ディベロップメント イミダゾ［４，５−ｃ］ピリジン化合物および抗ウイルス治療の方法

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Publication number Publication date
WO2006069193A2 (en) 2006-06-29
PL1841765T3 (pl) 2009-08-31
US20080188516A1 (en) 2008-08-07
WO2006069193A3 (en) 2006-08-10
DE602005013580D1 (de) 2009-05-07
AU2005319167A1 (en) 2006-06-29
CA2592388C (en) 2013-04-02
ATE426601T1 (de) 2009-04-15
HK1113570A1 (en) 2008-10-10
CA2592388A1 (en) 2006-06-29
DK1841765T5 (da) 2009-12-21
CY1109087T1 (el) 2014-07-02
US20060252791A1 (en) 2006-11-09
US7795276B2 (en) 2010-09-14
AU2005319167B2 (en) 2011-09-29
JP2012184265A (ja) 2012-09-27
NZ556624A (en) 2010-06-25
EP1841765A2 (en) 2007-10-10
SI1841765T1 (sl) 2009-08-31
DK1841765T3 (da) 2009-06-02
ES2324794T3 (es) 2009-08-14
PT1841765E (pt) 2009-05-14
EP1841765B1 (en) 2009-03-25

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