JP2008520369A5 - - Google Patents

Download PDF

Info

Publication number
JP2008520369A5
JP2008520369A5 JP2007543279A JP2007543279A JP2008520369A5 JP 2008520369 A5 JP2008520369 A5 JP 2008520369A5 JP 2007543279 A JP2007543279 A JP 2007543279A JP 2007543279 A JP2007543279 A JP 2007543279A JP 2008520369 A5 JP2008520369 A5 JP 2008520369A5
Authority
JP
Japan
Prior art keywords
flexible sheet
sheet
skin surface
central region
microneedle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007543279A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008520369A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/041854 external-priority patent/WO2006055795A1/en
Publication of JP2008520369A publication Critical patent/JP2008520369A/ja
Publication of JP2008520369A5 publication Critical patent/JP2008520369A5/ja
Withdrawn legal-status Critical Current

Links

JP2007543279A 2004-11-18 2005-11-18 目立たないマイクロニードルアレイアプリケーター Withdrawn JP2008520369A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62921504P 2004-11-18 2004-11-18
PCT/US2005/041854 WO2006055795A1 (en) 2004-11-18 2005-11-18 Low-profile microneedle array applicator

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012123179A Division JP5587946B2 (ja) 2004-11-18 2012-05-30 目立たないマイクロニードルアレイアプリケーター

Publications (2)

Publication Number Publication Date
JP2008520369A JP2008520369A (ja) 2008-06-19
JP2008520369A5 true JP2008520369A5 (enExample) 2009-01-08

Family

ID=35809616

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007543279A Withdrawn JP2008520369A (ja) 2004-11-18 2005-11-18 目立たないマイクロニードルアレイアプリケーター
JP2012123179A Expired - Lifetime JP5587946B2 (ja) 2004-11-18 2012-05-30 目立たないマイクロニードルアレイアプリケーター

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012123179A Expired - Lifetime JP5587946B2 (ja) 2004-11-18 2012-05-30 目立たないマイクロニードルアレイアプリケーター

Country Status (12)

Country Link
US (2) US8267889B2 (enExample)
EP (1) EP1833547A1 (enExample)
JP (2) JP2008520369A (enExample)
KR (2) KR20070102669A (enExample)
CN (1) CN101060883B (enExample)
AU (1) AU2005306422A1 (enExample)
BR (1) BRPI0517749A (enExample)
CA (1) CA2587505C (enExample)
IL (1) IL183204A (enExample)
MX (1) MX2007005813A (enExample)
WO (1) WO2006055795A1 (enExample)
ZA (1) ZA200705102B (enExample)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
CA2560840C (en) * 2004-03-24 2014-05-06 Corium International, Inc. Transdermal delivery device
BRPI0517749A (pt) 2004-11-18 2008-10-21 3M Innovative Properties Co dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação
US10035008B2 (en) 2005-04-07 2018-07-31 3M Innovative Properties Company System and method for tool feedback sensing
EP1904158B1 (en) 2005-06-24 2013-07-24 3M Innovative Properties Company Collapsible patch with microneedle array
WO2007028167A2 (en) * 2005-09-02 2007-03-08 Iomai Corporation Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs and uses thereof
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
KR100886633B1 (ko) * 2006-07-14 2009-03-04 호남석유화학 주식회사 전면부에 피부를 통해 체내로 전달하고자 하는 물질의 수용공간을 갖는 피부 침투용 미세 돌기 장치
EP1884223A1 (en) 2006-08-04 2008-02-06 IP Randwyck B.V. Wound-stimulating unit
EP2121111B1 (en) * 2007-01-22 2018-03-14 Corium International, Inc. Applicators for microneedle arrays
KR100893250B1 (ko) * 2007-02-28 2009-04-17 광주과학기술원 능동형 미세바늘 장치
JP4978245B2 (ja) * 2007-03-08 2012-07-18 凸版印刷株式会社 針状体、針状体製造方法および薬物輸送デバイス
WO2008130587A2 (en) 2007-04-16 2008-10-30 Corium International, Inc. Solvent-cast microneedle arrays containing active
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
GB2448493B (en) 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
JP5222512B2 (ja) * 2007-09-19 2013-06-26 凸版印刷株式会社 マイクロニードルチップ
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
KR101013581B1 (ko) 2008-08-06 2011-02-14 라종주 전기 피부 미용기
WO2010022326A2 (en) * 2008-08-22 2010-02-25 Us Worldmeds Llc Transdermal delivery of apomorphine using microneedles
JP5709137B2 (ja) * 2009-02-23 2015-04-30 株式会社 メドレックス 剣山型マイクロニードルのアプリケーター
US20110006458A1 (en) * 2009-04-24 2011-01-13 Corium International, Inc. Methods for manufacturing microprojection arrays
EP2462978A4 (en) * 2009-08-07 2013-01-02 Medrx Co Ltd APPLICATOR DEVICE WITH A STICK HOLDER MICRONADEL
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
USD638534S1 (en) 2010-01-08 2011-05-24 Ratio, Inc. Drug delivery device
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
USD619245S1 (en) 2010-01-08 2010-07-06 Ratio, Inc. Drug delivery device
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
WO2011089907A1 (ja) 2010-01-22 2011-07-28 株式会社メドレックス マイクロニードル貼付剤の貼付補助具
WO2011105496A1 (ja) 2010-02-24 2011-09-01 久光製薬株式会社 マイクロニードルデバイス
EP2566568B1 (en) 2010-05-04 2019-04-10 Corium International, Inc. Applicators for microneedles
EP2566501B1 (en) 2010-05-04 2019-03-13 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
WO2011141426A1 (en) 2010-05-10 2011-11-17 Tt Seed S.R.L. Needle device for detecting biosignals through the skin
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
CN101972499B (zh) * 2010-11-10 2016-07-06 吉林大学 轻松无痛输药装置
IT1403293B1 (it) 2010-12-27 2013-10-17 Fond Don Carlo Gnocchi Onlus Apparecchiatura ad aghi per la somministrazione transdermica di farmaci.
EP4309639A3 (en) 2011-06-14 2024-02-14 ViOL Co., Ltd. Apparatus and method for improving skin using a ra-effect or ra plus-effect
US9498611B2 (en) 2011-10-06 2016-11-22 Hisamitsu Pharmaceutical Co., Inc. Applicator
EP2765927B1 (en) 2011-10-12 2021-02-24 Vaxxas Pty Limited Delivery device
US10010707B2 (en) 2011-10-12 2018-07-03 3M Innovative Properties Company Integrated microneedle array delivery system
US20140236090A1 (en) * 2011-10-12 2014-08-21 3M Innovative Properties Company Integrated microneedle array delivery system
US8469900B2 (en) 2011-11-30 2013-06-25 Lincoln Diagnostics, Inc. Allergy testing device and method of testing for allergies
US9011350B2 (en) 2011-11-30 2015-04-21 Lincoln Diagnostics, Inc. Allergy testing device and method of testing for allergies
DE102011089723A1 (de) * 2011-12-23 2013-06-27 Robert Bosch Gmbh Mikronadelarray-Applikator und Verfahren zur Applikation eines Mikronadelarrays
WO2013166162A1 (en) 2012-05-01 2013-11-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Tip-loaded microneedle arrays for transdermal insertion
EP2852352B1 (en) 2012-05-04 2021-09-01 Roger Khouri Surgical tools
JP5593355B2 (ja) * 2012-07-23 2014-09-24 凸版印刷株式会社 針状体および針状体製造方法
EP2906285B1 (en) 2012-10-10 2019-06-12 3M Innovative Properties Company Applicator for applying a microneedle device to skin
EP2906284B8 (en) 2012-10-10 2021-01-20 Kindeva Drug Delivery L.P. Force-controlled applicator for applying a microneedle device to skin
US9789299B2 (en) * 2012-11-16 2017-10-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
CA2894718A1 (en) 2012-11-21 2014-05-30 Circuit Therapeutics, Inc. System and method for optogenetic therapy
MX375307B (es) 2012-12-21 2025-03-06 Corium Inc Microarreglo para la entrega de agente terapeutico y metodos de uso.
EP2968887B1 (en) 2013-03-12 2022-05-04 Corium, Inc. Microprojection applicators
CA2903583C (en) 2013-03-15 2021-12-28 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
AU2014237357B2 (en) 2013-03-15 2019-11-28 Corium Pharma Solutions, Inc. Multiple impact microprojection applicators and methods of use
MX380204B (es) * 2013-03-15 2025-03-12 Corium Inc Micrordenamiento para suministro de agente terapeútico y métodos de uso.
EP2968116A1 (en) 2013-03-15 2016-01-20 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US20150038897A1 (en) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Low-Profile Microneedle Patch Applicator
JP7229653B2 (ja) 2013-09-30 2023-02-28 ジョージア テック リサーチ コーポレイション マイクロニードルパッチ、システム、及び方法
EP3097942A4 (en) * 2014-01-24 2017-09-13 Toppan Printing Co., Ltd. Microneedle unit and microneedle assembly
JP6489025B2 (ja) * 2014-01-24 2019-03-27 凸版印刷株式会社 マイクロニードルユニット
US10994112B2 (en) 2014-02-05 2021-05-04 Amgen Inc. Drug delivery system with electromagnetic field generator
USD763504S1 (en) 2014-04-02 2016-08-09 Hisamitsu Pharmaceutical Co., Inc. Cosmetic pack sheet
WO2015164840A1 (en) 2014-04-24 2015-10-29 Georgia Tech Research Corporation Microneedles and methods of manufacture thereof
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
WO2016121499A1 (ja) * 2015-01-27 2016-08-04 凸版印刷株式会社 経皮投与デバイス
WO2016123665A1 (en) 2015-02-02 2016-08-11 Vaxxas Pty Limited Microprojection array applicator and method
US11116953B2 (en) 2015-02-13 2021-09-14 Medrx Co., Ltd. Microneedle applicator and microneedle patch application device
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
KR102135518B1 (ko) 2015-09-02 2020-07-17 히사미쓰 세이야꾸 가부시키가이샤 어플리케이터
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
AU2016333148B2 (en) 2015-09-28 2021-10-14 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
KR101757866B1 (ko) * 2015-10-08 2017-07-14 주식회사 라파스 마이크로니들패치 포장케이스
WO2017066768A1 (en) 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
JP6840389B2 (ja) 2015-12-21 2021-03-10 株式会社 メドレックス マイクロニードルパッチアプリケータ及びそのハウジング
WO2017120322A1 (en) 2016-01-05 2017-07-13 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
US10500351B2 (en) * 2016-02-12 2019-12-10 Shawn Michael Michels Aid for subcutaneous tissue injection and process of effecting the injection with the aid
CN110312546A (zh) 2016-12-16 2019-10-08 索伦托治疗有限公司 用于流体递送装置的施用机构及其使用方法
KR101745445B1 (ko) * 2017-01-25 2017-06-09 송득영 가압형 약물 주입 시스템
CN110709250B (zh) 2017-03-31 2022-10-11 瓦克萨斯私人有限公司 用于涂覆表面的设备和方法
JP2018191783A (ja) 2017-05-15 2018-12-06 富士フイルム株式会社 マイクロニードルアレイユニット、および容器
JP2018192177A (ja) * 2017-05-22 2018-12-06 コスメディ製薬株式会社 水溶性化粧用シート保持フィルム
EP3639010B1 (en) 2017-06-13 2025-08-06 Vaxxas Pty Limited Quality control of substrate coatings
EP3661587B1 (en) * 2017-08-04 2024-10-23 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (map)
KR20190027233A (ko) * 2017-09-06 2019-03-14 주식회사 라파스 마이크로니들 보호 성능이 개선된 마이크로니들 패치 및 이러한 마이크로니들 패치와 어플리케이터로 구성되는 마이크로니들 패치 어플리케이터 시스템
US10786203B1 (en) * 2018-01-30 2020-09-29 Daniel M. Besser Medical patch applicator device
WO2019166572A1 (en) 2018-02-28 2019-09-06 Pharming Intellectual Property B.V. Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor
EP3766537B1 (en) * 2018-03-13 2025-06-11 MEDRx Co., Ltd. Adhesion member and microneedle patch
CN108671385A (zh) * 2018-06-21 2018-10-19 陈宏� 一种穴位自动贴敷直压微针及使用方法
JP1632957S (enExample) 2018-10-30 2019-06-03
CN112996554B (zh) * 2018-10-31 2023-07-11 富士胶片株式会社 微针阵列器件
TWI846787B (zh) * 2018-12-25 2024-07-01 國立大學法人弘前大學 藥劑投予裝置及藥劑投予系統
DE102019200557A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
CN113874065A (zh) 2019-05-16 2021-12-31 联邦高等教育系统匹兹堡大学 用于皮肤和非皮肤药物递送的具有底切特征的微针阵列
JPWO2021251464A1 (enExample) * 2020-06-12 2021-12-16
US11389376B2 (en) 2020-12-21 2022-07-19 Mediccene Inc. Wearable intravenous fluid delivery system
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US12029562B2 (en) 2021-04-14 2024-07-09 Satio, Inc. Dermal patch system
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
KR20240089125A (ko) 2021-09-28 2024-06-20 바이오링크 인코포레이티드 마이크로니들 어레이 기반 연속 분석물 모니터링 장치용 어플리케이터 장치 및 마이크로니들 인클로저
USD1033641S1 (en) 2021-12-17 2024-07-02 Biolinq Incorporated Microneedle array sensor applicator device
KR102764041B1 (ko) * 2022-04-14 2025-02-07 주식회사 에스엔비아 마이크로니들 어플리케이터
USD1057153S1 (en) 2022-04-29 2025-01-07 Biolinq Incorporated Microneedle array sensor applicator device
CN120265352A (zh) * 2022-09-13 2025-07-04 微针生物医学公司 具有力反馈指示器的微针贴片
USD1085416S1 (en) * 2023-10-27 2025-07-22 Guangzhou Ekai Electronic Technology Co., Ltd. Skincare microneedling device for beauty machine

Family Cites Families (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
US3123212A (en) 1964-03-03 Multiple disposable intracutaneous injector package
US3072122A (en) 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
US3034507A (en) 1960-05-10 1962-05-15 American Cyanamid Co Intracutaneous injection device
US3136314A (en) 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3246647A (en) 1962-07-23 1966-04-19 American Cyanamid Co Disposable intracutaneous injector
US3221740A (en) 1962-08-31 1965-12-07 Rosenthal Sol Roy Injection device
GB1080986A (en) 1964-09-02 1967-08-31 Allen And Hanburys Surgical En Multiple puncture apparatus
US3322121A (en) 1965-11-26 1967-05-30 Oscar H Banker Skin-puncturing unit with a collapsible protective cover
US3510933A (en) 1967-05-26 1970-05-12 American Cyanamid Co Apparatus and method for continuously forming intracutaneous injectors
US3466131A (en) 1967-09-07 1969-09-09 Becton Dickinson Co Dispensing applicator package
US3512520A (en) 1967-11-01 1970-05-19 Michael N Cowan Antigenic test applicator
US3596660A (en) 1969-05-12 1971-08-03 Illinois Tool Works Injection device
US3675766A (en) 1970-02-04 1972-07-11 Sol Roy Rosenthal Multiple puncture injector device
US3688764A (en) 1970-08-20 1972-09-05 Bard Hamilton Co Inc Intracutaneous injection system
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3678150A (en) 1971-07-27 1972-07-18 American Cyanamid Co Process for improving the stability of ppd, qt and histoplasmin on tine applicators
DE2250293A1 (de) 1972-10-13 1974-04-25 Bayern Freistaat Impfstempel zur cutanen pockenimpfung mittels trockenimpfstoff
OA05448A (fr) 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
US4304241A (en) 1978-09-05 1981-12-08 Aller-Screen, Inc. Skin testing device
US4237906A (en) 1978-12-06 1980-12-09 Havstad Harold R Antigen injection assembly
GB2064329B (en) 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
FR2474856A1 (fr) 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
US4360016A (en) 1980-07-01 1982-11-23 Transidyne General Corp. Blood collecting device
US4503856A (en) 1981-06-29 1985-03-12 Sherwood Medical Company Lancet injector
US4517978A (en) 1983-01-13 1985-05-21 Levin Paul D Blood sampling instrument
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4627445A (en) 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
GB8710470D0 (en) 1987-05-01 1987-06-03 Mumford Ltd Owen Blood sampling devices
US4850973A (en) 1987-10-16 1989-07-25 Pavel Jordon & Associates Plastic device for injection and obtaining blood samples
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
GB2221394B (en) 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
US4924879A (en) 1988-10-07 1990-05-15 Brien Walter J O Blood lancet device
US4920977A (en) 1988-10-25 1990-05-01 Becton, Dickinson And Company Blood collection assembly with lancet and microcollection tube
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5402798A (en) 1991-07-18 1995-04-04 Swierczek; Remi Disposable skin perforator and blood testing device
DE4212315A1 (de) 1992-04-13 1993-10-14 Boehringer Mannheim Gmbh Blutlanzettenvorrichtung zur Entnahme von Blut für Diagnosezwecke
DE4212723C1 (de) * 1992-04-16 1993-11-04 Arta Plast Ab Tyresoe Lanzettenvorrichtung zum punktieren der haut
US5340572A (en) 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
JP2630197B2 (ja) 1993-04-28 1997-07-16 株式会社ニッショー 血液吸出器具
CA2149943C (en) 1994-05-23 1999-07-13 Kwang Kyun Jang Skin perforating device for transdermal medication
US5487726A (en) 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
US5636640A (en) * 1995-02-06 1997-06-10 Volunteers For Medical Engineering Liquid sampling and test apparatus
WO1996037155A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
ATE234129T1 (de) 1996-06-18 2003-03-15 Alza Corp Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
ATE231015T1 (de) 1996-09-17 2003-02-15 Deka Products Lp System zur medikamentenabgabe durch transport
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US5968633A (en) * 1997-06-06 1999-10-19 The Procter & Gamble Company Selectively-activatible sheet material for dispensing and dispersing a substance onto a target surface
DE69839969D1 (de) 1997-12-11 2008-10-16 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
WO1999029364A1 (en) 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
CA2312919C (en) 1997-12-31 2004-12-14 Minimed, Inc. Insertion device for an insertion set and method of using the same
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
CA2229522A1 (en) 1998-04-15 1999-10-15 Thomas Randall Inkpen Needle aid
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
JP2002517300A (ja) 1998-06-10 2002-06-18 ジョージア テック リサーチ コーポレイション 微小針デバイスおよび製造方法ならびにそれらの使用
GB9817662D0 (en) 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
WO2000012173A1 (en) 1998-08-31 2000-03-09 Johnson & Johnson Consumer Companies, Inc. Electrotransport device comprising blades
US6022368A (en) * 1998-11-30 2000-02-08 Gavronsky; Stas Acupuncture method and device
US6713291B2 (en) 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
EP1163024B1 (en) 1999-01-28 2003-12-17 Cyto Pulse Sciences, Inc. Delivery of macromolecules into cells
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
AU2005200910B2 (en) 1999-06-04 2006-08-03 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US20020095134A1 (en) 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
CN100402106C (zh) 1999-12-10 2008-07-16 阿尔萨公司 用于持续经过皮肤进行药物输送的皮肤处理装置
ES2253278T3 (es) 1999-12-10 2006-06-01 Alza Corporation Dispositivo y procedimiento para mejorar la perforacion cutanea con microprotuberancias.
US6881538B1 (en) 2000-03-05 2005-04-19 3M Innovative Properties Company Array comprising diamond-like glass film
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US7473244B2 (en) 2000-06-02 2009-01-06 The University Of Utah Research Foundation Active needle devices with integrated functionality
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6589202B1 (en) 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
US6440096B1 (en) 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
US6656147B1 (en) * 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
CA2425315C (en) 2000-10-13 2010-01-12 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
MXPA03003301A (es) 2000-10-13 2004-12-13 Johnson & Johnson Aplicador de un conjunto de microsalientes mediante impacto.
ATE416692T1 (de) 2000-10-13 2008-12-15 Alza Corp Mikronadelelementhalter für schlagapplikator
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
RU2282468C2 (ru) 2000-10-26 2006-08-27 Алза Корпорейшн Устройство для трансдермальной доставки лекарственных средств, имеющее микровыступы с покрытием
WO2002045771A2 (en) 2000-11-09 2002-06-13 Biovalve Technologies, Inc. Microneedle adapter
WO2002055128A2 (en) 2000-11-30 2002-07-18 Biovalve Technologies Inc Fluid delivery and measurement systems and methods
EP1345646A2 (en) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
US20020193729A1 (en) 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
CA2444883A1 (en) 2001-04-20 2002-10-31 Alza Corporation Microprojection array having a beneficial agent containing coating
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
WO2002100476A2 (en) 2001-06-08 2002-12-19 Becton, Dickinson And Company Device for manipulating a needle or abrader array
WO2003002069A2 (en) 2001-06-29 2003-01-09 Becton, Dickinson And Company Intradermal delivery of vaccines and gene therapeutic agents via microcannula
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
CN100349629C (zh) 2001-09-12 2007-11-21 贝克顿迪肯森公司 用于药物传送的微针为基础的笔装置和使用该装置的方法
EP1471953B1 (en) 2001-09-21 2011-02-16 Valeritas, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
JP4608187B2 (ja) * 2002-02-28 2011-01-05 リンテック株式会社 経皮吸収型製剤
US7858112B2 (en) 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
US6780171B2 (en) 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
EP1534376B1 (en) * 2002-06-25 2016-08-31 Theraject, Inc. Rapidly dissolving micro-perforator for drug delivery and other applications
MXPA05000597A (es) 2002-07-19 2005-04-28 3M Innovative Properties Co Dispositivos de microaguja y aparatos de administracion por microaguja.
ES2720098T3 (es) 2002-07-22 2019-07-17 Becton Dickinson Co Dispositivo de infusión similar a un parche
EP3075410B1 (en) 2002-08-29 2017-10-25 Becton, Dickinson and Company Microprotrusion arrays and methods for using same to deliver substances into tissue
EP1633250A2 (en) 2003-06-04 2006-03-15 Georgia Tech Research Corporation Drilling microneedle device
JP2007521092A (ja) 2003-07-02 2007-08-02 アルザ・コーポレーシヨン 小突起アレイの免疫化パッチおよび方法
BRPI0413539B8 (pt) 2003-08-12 2021-06-22 Becton Dickinson Co dispositivo para distribuir medicamento para o corpo de um paciente por injeção
US8353861B2 (en) 2003-09-18 2013-01-15 Texmac, Inc. Applicator for applying functional substances into human skin
AU2004285484A1 (en) 2003-10-24 2005-05-12 Alza Corporation Pretreatment method and system for enhancing transdermal drug delivery
AU2004287412A1 (en) 2003-10-28 2005-05-19 Alza Corporation Method and apparatus for reducing the incidence of tobacco use
KR20060099523A (ko) 2003-10-31 2006-09-19 알자 코포레이션 미세 돌출부 어레이를 위한 자가 작동 어플리케이터
US20050228313A1 (en) 2003-12-04 2005-10-13 University Technologies International Inc. Fluid sampling, analysis and delivery system
WO2005058393A2 (en) * 2003-12-18 2005-06-30 Novo Nordisk A/S Nozzle device with skin stretching means
US20070073220A1 (en) 2004-10-06 2007-03-29 Philip Bunce Inoculation device
BRPI0517749A (pt) 2004-11-18 2008-10-21 3M Innovative Properties Co dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
DE602005021541D1 (de) 2004-12-07 2010-07-08 3M Innovative Properties Co Verfahren zum formen einer mikronadel
EP1904158B1 (en) 2005-06-24 2013-07-24 3M Innovative Properties Company Collapsible patch with microneedle array
WO2007002521A2 (en) 2005-06-27 2007-01-04 3M Innovative Properties Company Microneedle array applicator device
US7658728B2 (en) 2006-01-10 2010-02-09 Yuzhakov Vadim V Microneedle array, patch, and applicator for transdermal drug delivery
US9119945B2 (en) 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism

Similar Documents

Publication Publication Date Title
JP2008520369A5 (enExample)
JP2012183358A5 (enExample)
JP2008520367A5 (enExample)
JP2007196067A5 (enExample)
JP2005271082A5 (enExample)
JP2008520371A5 (enExample)
JP2010537865A5 (enExample)
JP2010540203A5 (enExample)
DE602005027397D1 (de) Mikronadelanordungsapplikator und halter
BRPI0517749A (pt) dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação
WO2008096732A1 (ja) アレルギー診断用マイクロニードルデバイス
EP2489340A4 (en) ADHESIVE PLASTER
JP2015507546A5 (enExample)
BRPI0819250A2 (pt) aparelho de barbear ou depilar com um elemento de lâmina para barbeamento ou depilação preso pela parte posterior
TW200624975A (en) Apparatus and method for reducing slippage between structures in an interferometric modulator
EP2070710A3 (en) Image forming apparatus and foam application device
JP2015104144A5 (enExample)
ATE554329T1 (de) Verbindungseinheit und verbindungsverfahren einer solchen einheit
JP2015534875A5 (enExample)
JP2012101488A5 (enExample)
WO2010099180A3 (en) Support assembly for an ear
JP2015516820A5 (enExample)
ATE549956T1 (de) Haarentfernungsvorrichtung
DE602004021044D1 (de) Wärmeaktivierungsvorrichtung für eine wärmeempfindliche Haftfolie
DE602006019030D1 (de) Aktor