JP2008517064A - Ｐ３８ｍａｐキナーゼのイミダゾオキサゾールおよびイミダゾチアゾール阻害剤の合成 - Google Patents

Ｐ３８ｍａｐキナーゼのイミダゾオキサゾールおよびイミダゾチアゾール阻害剤の合成 Download PDF

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JP2008517064A
JP2008517064A JP2007537967A JP2007537967A JP2008517064A JP 2008517064 A JP2008517064 A JP 2008517064A JP 2007537967 A JP2007537967 A JP 2007537967A JP 2007537967 A JP2007537967 A JP 2007537967A JP 2008517064 A JP2008517064 A JP 2008517064A
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マーク アシュウェル，
マニッシュ タンドン，
ジャン−マルク ラピエール，
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アークル インコーポレイテッド
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
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  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
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JP2007537967A 2004-10-19 2005-10-19 Ｐ３８ｍａｐキナーゼのイミダゾオキサゾールおよびイミダゾチアゾール阻害剤の合成 Pending JP2008517064A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61987604P 2004-10-19 2004-10-19
PCT/US2005/037390 WO2006044869A1 (fr) 2004-10-19 2005-10-19 Synthese d'inhibiteurs d'imidazo-oxazole et d'imidazothiazole de la map kinase p38

Related Child Applications (1)

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JP2011265098A Division JP2012072177A (ja) 2004-10-19 2011-12-02 Ｐ３８ｍａｐキナーゼのイミダゾオキサゾールおよびイミダゾチアゾール阻害剤の合成

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JP2008517064A true JP2008517064A (ja) 2008-05-22

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JP2007537967A Pending JP2008517064A (ja) 2004-10-19 2005-10-19 Ｐ３８ｍａｐキナーゼのイミダゾオキサゾールおよびイミダゾチアゾール阻害剤の合成
JP2011265098A Withdrawn JP2012072177A (ja) 2004-10-19 2011-12-02 Ｐ３８ｍａｐキナーゼのイミダゾオキサゾールおよびイミダゾチアゾール阻害剤の合成

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JP2011265098A Withdrawn JP2012072177A (ja) 2004-10-19 2011-12-02 Ｐ３８ｍａｐキナーゼのイミダゾオキサゾールおよびイミダゾチアゾール阻害剤の合成

Country Status (5)

Country Link
US (1) US8178672B2 (fr)
EP (2) EP2258704A1 (fr)
JP (2) JP2008517064A (fr)
CA (1) CA2584368A1 (fr)
WO (1) WO2006044869A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1633758B1 (fr) 2003-05-15 2011-11-23 Arqule, Inc. Inhibiteurs de p38 et leurs methodes d'utilisation
EP2258704A1 (fr) 2004-10-19 2010-12-08 ArQule, Inc. Synthese d'inhibiteurs d'imidazo-oxazole et d'imidazothiazole de la map kinase p38
WO2007123892A2 (fr) * 2006-04-17 2007-11-01 Arqule Inc. Inhibiteurs raf et leurs utilisations
MX2008014672A (es) * 2006-05-19 2009-03-09 Abbott Lab Derivados de alcano azabiciclico sustituidos con bicicloheterociclo fusionado activos en el sistema nervioso central.
EP1992344A1 (fr) 2007-05-18 2008-11-19 Institut Curie P38 alpha comme cible therapeutique pour les maladies associées á une mutation de FGFR3
JP2010528991A (ja) * 2007-05-21 2010-08-26 エスジーエックス ファーマシューティカルズ、インコーポレイテッド 複素環式キナーゼ調節因子
BRPI0813355A2 (pt) 2007-06-22 2014-12-30 Arqule Inc Compostos de quinazolinona e métodos de uso dos mesmos
EP2170337A4 (fr) 2007-06-28 2013-12-18 Abbvie Inc Nouvelles triazolopyridazines
AU2008281543A1 (en) * 2007-08-01 2009-02-05 Pfizer Inc. Pyrazole compounds and their use as Raf inhibitors
JP4792128B2 (ja) 2007-10-12 2011-10-12 アークル インコーポレイテッド 癌に対するｈｓｐ９０阻害剤としての５−（２−ヒドロキシフェニル）テトラゾール
US8067409B2 (en) 2007-11-27 2011-11-29 Abbott Laboratories Protein kinase inhibitors
US20100183600A1 (en) * 2008-12-05 2010-07-22 Arqule, Inc. RAF Inhibitors and Their Uses
JP7258748B2 (ja) 2016-11-22 2023-04-17 ダナ－ファーバー キャンサー インスティテュート， インコーポレイテッド サイクリン依存性キナーゼ１２（ｃｄｋ１２）の阻害剤およびその使用
WO2023141571A1 (fr) * 2022-01-21 2023-07-27 Prelude Therapeutics, Incorporated Inhibiteurs de cdk et leur utilisation en tant que produits pharmaceutiques

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001519381A (ja) * 1997-10-10 2001-10-23 インペリアル・カレッジ・イノベイションズ・リミテッド 子宮収縮管理のためのｃｓａｉｄｔｍ化合物の使用
WO2002083667A2 (fr) * 2001-04-13 2002-10-24 Vertex Pharmaceuticals Incorporated Inhibiteurs de c-jun n-terminal kinases (jnk) et d'autres proteines kinases
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