JP2008515798A5 - - Google Patents
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- Publication number
- JP2008515798A5 JP2008515798A5 JP2007534851A JP2007534851A JP2008515798A5 JP 2008515798 A5 JP2008515798 A5 JP 2008515798A5 JP 2007534851 A JP2007534851 A JP 2007534851A JP 2007534851 A JP2007534851 A JP 2007534851A JP 2008515798 A5 JP2008515798 A5 JP 2008515798A5
- Authority
- JP
- Japan
- Prior art keywords
- aliphatic
- optionally substituted
- independently
- ring
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *Cc(c(S=C)c1)ccc1[Rh] Chemical compound *Cc(c(S=C)c1)ccc1[Rh] 0.000 description 1
- UWRWHOKKUJISAM-UHFFFAOYSA-N CC(C)c(cccc1)c1SC Chemical compound CC(C)c(cccc1)c1SC UWRWHOKKUJISAM-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61576104P | 2004-10-04 | 2004-10-04 | |
| US60/615,761 | 2004-10-04 | ||
| PCT/US2005/035458 WO2006041773A2 (en) | 2004-10-04 | 2005-10-03 | Lactam compounds useful as protein kinase inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012019746A Division JP2012092143A (ja) | 2004-10-04 | 2012-02-01 | タンパク質キナーゼインヒビターとして有用なラクタム化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008515798A JP2008515798A (ja) | 2008-05-15 |
| JP2008515798A5 true JP2008515798A5 (https=) | 2008-11-20 |
| JP5002460B2 JP5002460B2 (ja) | 2012-08-15 |
Family
ID=35789256
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007534851A Expired - Fee Related JP5002460B2 (ja) | 2004-10-04 | 2005-10-03 | タンパク質キナーゼインヒビターとして有用なラクタム化合物 |
| JP2012019746A Withdrawn JP2012092143A (ja) | 2004-10-04 | 2012-02-01 | タンパク質キナーゼインヒビターとして有用なラクタム化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012019746A Withdrawn JP2012092143A (ja) | 2004-10-04 | 2012-02-01 | タンパク質キナーゼインヒビターとして有用なラクタム化合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7459448B2 (https=) |
| EP (2) | EP2439207A1 (https=) |
| JP (2) | JP5002460B2 (https=) |
| CN (2) | CN101068815B (https=) |
| AU (1) | AU2005294575B2 (https=) |
| CA (1) | CA2582235A1 (https=) |
| WO (1) | WO2006041773A2 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005294575B2 (en) | 2004-10-04 | 2011-11-24 | Millennium Pharmaceuticals, Inc. | Lactam compounds useful as protein kinase inhibitors |
| US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| PE20080145A1 (es) * | 2006-03-21 | 2008-02-11 | Janssen Pharmaceutica Nv | Tetrahidro-pirimidoazepinas como moduladores de trpv1 |
| US8735411B2 (en) | 2006-10-02 | 2014-05-27 | Abbvie Inc. | Macrocyclic benzofused pyrimidine derivatives |
| US7985745B2 (en) * | 2006-10-02 | 2011-07-26 | Abbott Laboratories | Method for pain treatment |
| SG158147A1 (en) | 2006-10-09 | 2010-01-29 | Takeda Pharmaceutical | Kinase inhibitors |
| CA2695753A1 (en) * | 2007-08-15 | 2009-02-19 | Vertex Pharmaceuticals Incorporated | Compounds useful as protein kinases inhibitors |
| EP2205603B1 (en) * | 2007-09-28 | 2014-01-15 | Cyclacel Limited | Pyrimidine derivatives as protein kinase inhibitors |
| WO2009078999A1 (en) | 2007-12-17 | 2009-06-25 | Janssen Pharmaceutica N.V. | Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of trpv1 |
| WO2009081222A1 (en) | 2007-12-21 | 2009-07-02 | Glenmark Pharmaceuticals, S.A. | Substituted tricyclic pyridine or pyrimidine vanilloid receptor ligands |
| GB0800383D0 (en) * | 2008-01-10 | 2008-02-20 | Univ Strathclyde | Weight reducing compounds |
| EP2100894A1 (en) | 2008-03-12 | 2009-09-16 | 4Sc Ag | Pyridopyrimidines used as Plk1 (polo-like kinase) inhibitors |
| US7998952B2 (en) * | 2008-12-05 | 2011-08-16 | Millennium Pharmaceuticals, Inc. | Thiolactams and uses thereof |
| RS57869B1 (sr) | 2009-06-17 | 2018-12-31 | Vertex Pharma | Inhibitori replikacije virusa gripa |
| AU2011343642A1 (en) | 2010-12-16 | 2013-05-02 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| JP5959537B2 (ja) * | 2011-01-28 | 2016-08-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換ピリジニル−ピリミジン及び医薬としてのその使用 |
| CN102174016A (zh) * | 2011-03-02 | 2011-09-07 | 宁波人健药业集团有限公司 | 一种制备7-氯-2,3,4,5-四氢-1h-1-苯并氮杂卓-2,5-二酮的方法 |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| WO2013033093A1 (en) * | 2011-08-29 | 2013-03-07 | Biocryst Pharmaceuticals, Inc. | Heterocyclic compounds as janus kinase inhibitors |
| SG10201707409PA (en) | 2013-03-13 | 2017-10-30 | Forma Therapeutics Inc | Novel compounds and compositions for inhibition of fasn |
| HRP20181272T1 (hr) | 2013-11-13 | 2018-10-05 | Vertex Pharmaceuticals Incorporated | Postupci priprave inhibitora replikacije virusa influence |
| RS59144B1 (sr) | 2013-11-13 | 2019-09-30 | Vertex Pharma | Inhibitori replikacije virusa influence |
| CN103601678B (zh) * | 2013-11-21 | 2015-02-11 | 爱斯特（成都）医药技术有限公司 | 7-氯-1,2,3,4-四氢苯并[b]氮杂卓-5-酮的合成方法 |
| CN106458868A (zh) | 2014-04-17 | 2017-02-22 | 伊谬诺米特医疗有限公司 | 胍化合物及其用途 |
| JP6704416B2 (ja) | 2015-05-13 | 2020-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | インフルエンザウイルスの複製の阻害剤を調製する方法 |
| JP6857617B2 (ja) | 2015-05-13 | 2021-04-14 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | インフルエンザウイルスの複製の阻害剤 |
| WO2017070235A1 (en) * | 2015-10-19 | 2017-04-27 | Attenua, Inc. | Antitussive compositions and methods |
| AU2017259654B2 (en) | 2016-05-06 | 2020-02-27 | Shanghai De Novo Pharmatech Co., Ltd. | Benzazepine derivative, preparation method, pharmaceutical composition and use thereof |
| US10793554B2 (en) | 2018-10-29 | 2020-10-06 | Forma Therapeutics, Inc. | Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06172355A (ja) | 1992-04-14 | 1994-06-21 | Mect Corp | ピリミジン誘導体およびそれを有効成分とする血小板凝集阻止剤 |
| DE4332168A1 (de) | 1993-02-22 | 1995-03-23 | Thomae Gmbh Dr K | Cyclische Derivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| US5686445A (en) * | 1993-07-29 | 1997-11-11 | American Cyanamid Company | Pyridobenzoxazepine and pyridobenzothiazepine vasopressin antagonists |
| US5428040A (en) | 1993-08-31 | 1995-06-27 | The Du Pont Merck Pharmaceutical Company | Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents |
| JP3531169B2 (ja) | 1996-06-11 | 2004-05-24 | 三菱ウェルファーマ株式会社 | 縮合ヘテロ環化合物およびその医薬用途 |
| WO1997047624A1 (en) | 1996-06-13 | 1997-12-18 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| US6057329A (en) * | 1996-12-23 | 2000-05-02 | Celltech Therapeutics Limited | Fused polycyclic 2-aminopyrimidine derivatives |
| US6723498B1 (en) | 1999-06-30 | 2004-04-20 | Millennium Pharmaceuticals, Inc. | Chk1 and uses thereof |
| FR2804959B1 (fr) * | 2000-02-15 | 2006-04-28 | Centre Nat Rech Scient | Utilisation de derives de paullones pour la fabrication de medicaments |
| US6369222B1 (en) | 2000-07-18 | 2002-04-09 | Hoffmann-La Roche Inc. | mGluR antagonists and a method for their synthesis |
| US6610677B2 (en) * | 2000-09-15 | 2003-08-26 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| WO2002088079A2 (en) | 2001-05-01 | 2002-11-07 | Bristol-Myers Squibb Company | Dual inhibitors of pde 7 and pde 4 |
| US7105667B2 (en) | 2001-05-01 | 2006-09-12 | Bristol-Myers Squibb Co. | Fused heterocyclic compounds and use thereof |
| US6686352B2 (en) * | 2001-05-18 | 2004-02-03 | Hoffmann-La Roche Inc. | Substituted imidazo [1,5-a] pyrimido [5,4-d] [1] benzazepine derivatives |
| AU2003242252A1 (en) | 2002-06-07 | 2003-12-22 | Kyowa Hakko Kogyo Co., Ltd. | Bicyclic pyrimidine derivatives |
| ES2545666T3 (es) * | 2003-02-27 | 2015-09-14 | Abbvie Inc. | 5,10-Dihidro-11H-dibenzo[b,e][1,4]diazepin-11-ona como inhibidores de quinasa |
| WO2005007655A1 (en) | 2003-07-21 | 2005-01-27 | Pfizer Products Inc. | Nicotine addiction reducing heteroaryl fused azapolycyclic compounds |
| CN1897950A (zh) | 2003-10-14 | 2007-01-17 | 惠氏公司 | 稠合芳基和杂芳基衍生物及其使用方法 |
| ES2540987T3 (es) * | 2004-05-14 | 2015-07-15 | Millennium Pharmaceuticals, Inc. | Métodos para preparar inhibidores de la aurora cinasa |
| AU2005294575B2 (en) * | 2004-10-04 | 2011-11-24 | Millennium Pharmaceuticals, Inc. | Lactam compounds useful as protein kinase inhibitors |
| PE20070171A1 (es) | 2005-06-30 | 2007-03-08 | Boehringer Ingelheim Int | GLICINAMIDAS SUSTITUIDAS CON EFECTO ANTITROMBOTICO E INHIBIDOR DEL FACTOR Xa |
| US7998952B2 (en) * | 2008-12-05 | 2011-08-16 | Millennium Pharmaceuticals, Inc. | Thiolactams and uses thereof |
-
2005
- 2005-10-03 AU AU2005294575A patent/AU2005294575B2/en not_active Ceased
- 2005-10-03 CN CN2005800414294A patent/CN101068815B/zh not_active Expired - Fee Related
- 2005-10-03 EP EP11182921A patent/EP2439207A1/en not_active Withdrawn
- 2005-10-03 WO PCT/US2005/035458 patent/WO2006041773A2/en not_active Ceased
- 2005-10-03 JP JP2007534851A patent/JP5002460B2/ja not_active Expired - Fee Related
- 2005-10-03 US US11/242,413 patent/US7459448B2/en not_active Expired - Lifetime
- 2005-10-03 CA CA002582235A patent/CA2582235A1/en not_active Abandoned
- 2005-10-03 EP EP05812472.8A patent/EP1799684B1/en not_active Expired - Lifetime
- 2005-10-03 CN CN2012102393383A patent/CN102766142A/zh active Pending
-
2008
- 2008-09-04 US US12/231,661 patent/US7935694B2/en not_active Expired - Lifetime
-
2010
- 2010-10-13 US US12/903,370 patent/US20110039820A1/en not_active Abandoned
-
2012
- 2012-02-01 JP JP2012019746A patent/JP2012092143A/ja not_active Withdrawn
- 2012-03-14 US US13/419,663 patent/US20120178739A1/en not_active Abandoned
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