JP2008512458A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008512458A5 JP2008512458A5 JP2007531265A JP2007531265A JP2008512458A5 JP 2008512458 A5 JP2008512458 A5 JP 2008512458A5 JP 2007531265 A JP2007531265 A JP 2007531265A JP 2007531265 A JP2007531265 A JP 2007531265A JP 2008512458 A5 JP2008512458 A5 JP 2008512458A5
- Authority
- JP
- Japan
- Prior art keywords
- halogen
- alkyl
- phenyl
- alkenyl
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60776604P | 2004-09-07 | 2004-09-07 | |
| PCT/US2005/031696 WO2006029146A2 (en) | 2004-09-07 | 2005-09-06 | 6H-[1]BENZOPYRANO[4,3-b]QUINOLINES AND THEIR USE AS ESTROGENIC AGENTS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008512458A JP2008512458A (ja) | 2008-04-24 |
| JP2008512458A5 true JP2008512458A5 (https=) | 2008-10-23 |
Family
ID=35677606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007531265A Pending JP2008512458A (ja) | 2004-09-07 | 2005-09-06 | 6H−[1]ベンゾピラノ[4,3−b]キノリン及びエストロゲン様物質としてのそれらの使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7354927B2 (https=) |
| EP (1) | EP1789420A2 (https=) |
| JP (1) | JP2008512458A (https=) |
| KR (1) | KR20070061536A (https=) |
| CN (1) | CN101052641A (https=) |
| AU (1) | AU2005282554A1 (https=) |
| BR (1) | BRPI0514974A (https=) |
| CA (1) | CA2578164A1 (https=) |
| EC (1) | ECSP077302A (https=) |
| IL (1) | IL181514A0 (https=) |
| MX (1) | MX2007002789A (https=) |
| NO (1) | NO20071364L (https=) |
| RU (1) | RU2007106870A (https=) |
| WO (1) | WO2006029146A2 (https=) |
| ZA (1) | ZA200701950B (https=) |
Families Citing this family (89)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2564694T3 (es) | 2003-09-12 | 2016-03-28 | Vessix Vascular, Inc. | Sistema de remodelación y / o ablación excéntrica seleccionable de material ateroesclerótico |
| US20060004087A1 (en) * | 2004-07-01 | 2006-01-05 | Wyeth | Tetracyclic compounds as estrogen ligands |
| US8396548B2 (en) | 2008-11-14 | 2013-03-12 | Vessix Vascular, Inc. | Selective drug delivery in a lumen |
| US8920414B2 (en) | 2004-09-10 | 2014-12-30 | Vessix Vascular, Inc. | Tuned RF energy and electrical tissue characterization for selective treatment of target tissues |
| US9713730B2 (en) | 2004-09-10 | 2017-07-25 | Boston Scientific Scimed, Inc. | Apparatus and method for treatment of in-stent restenosis |
| US7423045B2 (en) | 2005-06-28 | 2008-09-09 | Cv Therapeutics, Inc. | ABCA1 elevating compounds |
| AR059574A1 (es) * | 2006-02-14 | 2008-04-16 | Wyeth Corp | Formulaciones farmaceuticas acuosas de ligandos selectivos er-beta |
| US8019435B2 (en) | 2006-05-02 | 2011-09-13 | Boston Scientific Scimed, Inc. | Control of arterial smooth muscle tone |
| EP2076198A4 (en) | 2006-10-18 | 2009-12-09 | Minnow Medical Inc | Inducing Desired Temperatreating Effects on Body Weave |
| EP2076194B1 (en) | 2006-10-18 | 2013-04-24 | Vessix Vascular, Inc. | System for inducing desirable temperature effects on body tissue |
| CA2672428A1 (en) * | 2006-12-27 | 2008-07-03 | Cv Therapeutics, Inc. | Abca1 elevating compounds |
| EA026578B1 (ru) | 2007-01-22 | 2017-04-28 | ДЖиТиЭкс, ИНК. | Вещества, связывающие ядерные рецепторы |
| US9623021B2 (en) * | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
| US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
| JP5307900B2 (ja) | 2008-11-17 | 2013-10-02 | べシックス・バスキュラー・インコーポレイテッド | 組織トポグラフィの知識によらないエネルギーの選択的な蓄積 |
| CN103068330B (zh) | 2010-04-09 | 2016-06-29 | Vessix血管股份有限公司 | 用于治疗组织的功率发生和控制装置 |
| US9192790B2 (en) | 2010-04-14 | 2015-11-24 | Boston Scientific Scimed, Inc. | Focused ultrasonic renal denervation |
| US8473067B2 (en) | 2010-06-11 | 2013-06-25 | Boston Scientific Scimed, Inc. | Renal denervation and stimulation employing wireless vascular energy transfer arrangement |
| US9408661B2 (en) | 2010-07-30 | 2016-08-09 | Patrick A. Haverkost | RF electrodes on multiple flexible wires for renal nerve ablation |
| US9155589B2 (en) | 2010-07-30 | 2015-10-13 | Boston Scientific Scimed, Inc. | Sequential activation RF electrode set for renal nerve ablation |
| US9084609B2 (en) | 2010-07-30 | 2015-07-21 | Boston Scientific Scime, Inc. | Spiral balloon catheter for renal nerve ablation |
| US9358365B2 (en) | 2010-07-30 | 2016-06-07 | Boston Scientific Scimed, Inc. | Precision electrode movement control for renal nerve ablation |
| US9463062B2 (en) | 2010-07-30 | 2016-10-11 | Boston Scientific Scimed, Inc. | Cooled conductive balloon RF catheter for renal nerve ablation |
| US8974451B2 (en) | 2010-10-25 | 2015-03-10 | Boston Scientific Scimed, Inc. | Renal nerve ablation using conductive fluid jet and RF energy |
| US9220558B2 (en) | 2010-10-27 | 2015-12-29 | Boston Scientific Scimed, Inc. | RF renal denervation catheter with multiple independent electrodes |
| US9028485B2 (en) | 2010-11-15 | 2015-05-12 | Boston Scientific Scimed, Inc. | Self-expanding cooling electrode for renal nerve ablation |
| US9668811B2 (en) | 2010-11-16 | 2017-06-06 | Boston Scientific Scimed, Inc. | Minimally invasive access for renal nerve ablation |
| US9089350B2 (en) | 2010-11-16 | 2015-07-28 | Boston Scientific Scimed, Inc. | Renal denervation catheter with RF electrode and integral contrast dye injection arrangement |
| US9326751B2 (en) | 2010-11-17 | 2016-05-03 | Boston Scientific Scimed, Inc. | Catheter guidance of external energy for renal denervation |
| US9060761B2 (en) | 2010-11-18 | 2015-06-23 | Boston Scientific Scime, Inc. | Catheter-focused magnetic field induced renal nerve ablation |
| US9023034B2 (en) | 2010-11-22 | 2015-05-05 | Boston Scientific Scimed, Inc. | Renal ablation electrode with force-activatable conduction apparatus |
| US9192435B2 (en) | 2010-11-22 | 2015-11-24 | Boston Scientific Scimed, Inc. | Renal denervation catheter with cooled RF electrode |
| US20120157993A1 (en) | 2010-12-15 | 2012-06-21 | Jenson Mark L | Bipolar Off-Wall Electrode Device for Renal Nerve Ablation |
| US9220561B2 (en) | 2011-01-19 | 2015-12-29 | Boston Scientific Scimed, Inc. | Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury |
| AU2012283908B2 (en) | 2011-07-20 | 2017-02-16 | Boston Scientific Scimed, Inc. | Percutaneous devices and methods to visualize, target and ablate nerves |
| CN103813829B (zh) | 2011-07-22 | 2016-05-18 | 波士顿科学西美德公司 | 具有可定位于螺旋引导件中的神经调制元件的神经调制系统 |
| EP2765942B1 (en) | 2011-10-10 | 2016-02-24 | Boston Scientific Scimed, Inc. | Medical devices including ablation electrodes |
| US9420955B2 (en) | 2011-10-11 | 2016-08-23 | Boston Scientific Scimed, Inc. | Intravascular temperature monitoring system and method |
| WO2013055815A1 (en) | 2011-10-11 | 2013-04-18 | Boston Scientific Scimed, Inc. | Off -wall electrode device for nerve modulation |
| US9364284B2 (en) | 2011-10-12 | 2016-06-14 | Boston Scientific Scimed, Inc. | Method of making an off-wall spacer cage |
| US9079000B2 (en) | 2011-10-18 | 2015-07-14 | Boston Scientific Scimed, Inc. | Integrated crossing balloon catheter |
| US9162046B2 (en) | 2011-10-18 | 2015-10-20 | Boston Scientific Scimed, Inc. | Deflectable medical devices |
| CN108095821B (zh) | 2011-11-08 | 2021-05-25 | 波士顿科学西美德公司 | 孔部肾神经消融 |
| US9119600B2 (en) | 2011-11-15 | 2015-09-01 | Boston Scientific Scimed, Inc. | Device and methods for renal nerve modulation monitoring |
| US9119632B2 (en) | 2011-11-21 | 2015-09-01 | Boston Scientific Scimed, Inc. | Deflectable renal nerve ablation catheter |
| CN102584841B (zh) * | 2011-12-16 | 2014-11-12 | 浙江工业大学 | 一种喹啉香豆素衍生物及其制备方法及用途 |
| US9265969B2 (en) | 2011-12-21 | 2016-02-23 | Cardiac Pacemakers, Inc. | Methods for modulating cell function |
| JP6158830B2 (ja) | 2011-12-23 | 2017-07-05 | べシックス・バスキュラー・インコーポレイテッド | 身体通路の組織又は身体通路に隣接する組織をリモデリングするためのシステム、方法及び装置 |
| WO2013101452A1 (en) | 2011-12-28 | 2013-07-04 | Boston Scientific Scimed, Inc. | Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements |
| US9050106B2 (en) | 2011-12-29 | 2015-06-09 | Boston Scientific Scimed, Inc. | Off-wall electrode device and methods for nerve modulation |
| WO2013169927A1 (en) | 2012-05-08 | 2013-11-14 | Boston Scientific Scimed, Inc. | Renal nerve modulation devices |
| WO2014032016A1 (en) | 2012-08-24 | 2014-02-27 | Boston Scientific Scimed, Inc. | Intravascular catheter with a balloon comprising separate microporous regions |
| WO2014043687A2 (en) | 2012-09-17 | 2014-03-20 | Boston Scientific Scimed, Inc. | Self-positioning electrode system and method for renal nerve modulation |
| WO2014047411A1 (en) | 2012-09-21 | 2014-03-27 | Boston Scientific Scimed, Inc. | System for nerve modulation and innocuous thermal gradient nerve block |
| WO2014047454A2 (en) | 2012-09-21 | 2014-03-27 | Boston Scientific Scimed, Inc. | Self-cooling ultrasound ablation catheter |
| JP6074051B2 (ja) | 2012-10-10 | 2017-02-01 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 血管内神経変調システム及び医療用デバイス |
| US9956033B2 (en) | 2013-03-11 | 2018-05-01 | Boston Scientific Scimed, Inc. | Medical devices for modulating nerves |
| US9693821B2 (en) | 2013-03-11 | 2017-07-04 | Boston Scientific Scimed, Inc. | Medical devices for modulating nerves |
| US9808311B2 (en) | 2013-03-13 | 2017-11-07 | Boston Scientific Scimed, Inc. | Deflectable medical devices |
| EP2967725B1 (en) | 2013-03-15 | 2019-12-11 | Boston Scientific Scimed, Inc. | Control unit for detecting electrical leakage between electrode pads and system comprising such a control unit |
| US10265122B2 (en) | 2013-03-15 | 2019-04-23 | Boston Scientific Scimed, Inc. | Nerve ablation devices and related methods of use |
| JP6220044B2 (ja) | 2013-03-15 | 2017-10-25 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 腎神経アブレーションのための医療用デバイス |
| EP3010437A1 (en) | 2013-06-21 | 2016-04-27 | Boston Scientific Scimed, Inc. | Renal denervation balloon catheter with ride along electrode support |
| WO2014205399A1 (en) | 2013-06-21 | 2014-12-24 | Boston Scientific Scimed, Inc. | Medical devices for renal nerve ablation having rotatable shafts |
| US9707036B2 (en) | 2013-06-25 | 2017-07-18 | Boston Scientific Scimed, Inc. | Devices and methods for nerve modulation using localized indifferent electrodes |
| JP6204579B2 (ja) | 2013-07-01 | 2017-09-27 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 腎神経アブレーション用医療器具 |
| US10413357B2 (en) | 2013-07-11 | 2019-09-17 | Boston Scientific Scimed, Inc. | Medical device with stretchable electrode assemblies |
| WO2015006480A1 (en) | 2013-07-11 | 2015-01-15 | Boston Scientific Scimed, Inc. | Devices and methods for nerve modulation |
| US9925001B2 (en) | 2013-07-19 | 2018-03-27 | Boston Scientific Scimed, Inc. | Spiral bipolar electrode renal denervation balloon |
| US10342609B2 (en) | 2013-07-22 | 2019-07-09 | Boston Scientific Scimed, Inc. | Medical devices for renal nerve ablation |
| CN105392435B (zh) | 2013-07-22 | 2018-11-09 | 波士顿科学国际有限公司 | 具有扭绞球囊的肾神经消融导管 |
| US10722300B2 (en) | 2013-08-22 | 2020-07-28 | Boston Scientific Scimed, Inc. | Flexible circuit having improved adhesion to a renal nerve modulation balloon |
| WO2015035047A1 (en) | 2013-09-04 | 2015-03-12 | Boston Scientific Scimed, Inc. | Radio frequency (rf) balloon catheter having flushing and cooling capability |
| WO2015038947A1 (en) | 2013-09-13 | 2015-03-19 | Boston Scientific Scimed, Inc. | Ablation balloon with vapor deposited cover layer |
| EP3057488B1 (en) | 2013-10-14 | 2018-05-16 | Boston Scientific Scimed, Inc. | High resolution cardiac mapping electrode array catheter |
| US11246654B2 (en) | 2013-10-14 | 2022-02-15 | Boston Scientific Scimed, Inc. | Flexible renal nerve ablation devices and related methods of use and manufacture |
| US9962223B2 (en) | 2013-10-15 | 2018-05-08 | Boston Scientific Scimed, Inc. | Medical device balloon |
| US9770606B2 (en) | 2013-10-15 | 2017-09-26 | Boston Scientific Scimed, Inc. | Ultrasound ablation catheter with cooling infusion and centering basket |
| US10945786B2 (en) | 2013-10-18 | 2021-03-16 | Boston Scientific Scimed, Inc. | Balloon catheters with flexible conducting wires and related methods of use and manufacture |
| US10271898B2 (en) | 2013-10-25 | 2019-04-30 | Boston Scientific Scimed, Inc. | Embedded thermocouple in denervation flex circuit |
| EP3091922B1 (en) | 2014-01-06 | 2018-10-17 | Boston Scientific Scimed, Inc. | Tear resistant flex circuit assembly |
| EP3424453B1 (en) | 2014-02-04 | 2026-04-01 | Boston Scientific Scimed, Inc. | Alternative placement of thermal sensors on bipolar electrode |
| US11000679B2 (en) | 2014-02-04 | 2021-05-11 | Boston Scientific Scimed, Inc. | Balloon protection and rewrapping devices and related methods of use |
| CN105602548B (zh) * | 2015-12-19 | 2018-11-06 | 江西冠能光电材料有限公司 | 含呋喃的电致红色发光材料及其制备的有机电致发光器件 |
| CN106928243A (zh) * | 2017-03-30 | 2017-07-07 | 毛阿龙 | 具有生物活性的苯并哌啶并苯胺基类化合物的制备方法 |
| CN106977523A (zh) * | 2017-03-30 | 2017-07-25 | 河南师范大学 | 具有苯基并四氢吡咯结构的fshr拮抗剂及其制备方法 |
| CN106967076A (zh) * | 2017-03-30 | 2017-07-21 | 河南师范大学 | 一种具有6h‑二苯并吡喃结构化合物及其制备方法 |
| CN112424205B (zh) * | 2018-07-12 | 2023-10-31 | 伊莱利利公司 | 选择性的雌激素受体降解剂 |
| CN112225744A (zh) * | 2020-08-31 | 2021-01-15 | 兰州大学 | 一种6H-苯并吡喃并[3,4-b]喹啉类化合物及其制备方法和用途 |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3518273A (en) | 1966-08-03 | 1970-06-30 | Warner Lambert Pharmaceutical | Benzopyranquinolinol derivatives and process for their production |
| US3518258A (en) | 1967-05-09 | 1970-06-30 | Warner Lambert Pharmaceutical | Pyrano(3,2-i)quinolizine and process for the production |
| US3493579A (en) | 1967-05-29 | 1970-02-03 | Little Inc A | 1,4-ethano-5h-(1)benzopyrano (3,4-b)pyridines |
| US3541100A (en) | 1967-12-14 | 1970-11-17 | American Cyanamid Co | Benzheteroazolo(2,3-a)isoquinolium salts |
| US3518272A (en) | 1968-02-05 | 1970-06-30 | Warner Lambert Pharmaceutical | Tetrahydro benzopyranoquinolines and process for their production |
| US3600375A (en) | 1968-03-25 | 1971-08-17 | Dow Chemical Co | Azomethanodioxocins |
| US3551565A (en) | 1968-04-26 | 1970-12-29 | Geigy Chem Corp | Pharmaceutical compositions and uses of oxazinoisoquinoline derivatives |
| US4418068A (en) | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
| SU1051092A1 (ru) | 1982-07-05 | 1983-10-30 | Ростовский Ордена Трудового Красного Знамени Государственный Университет Им.М.А.Суслова | Способ получени тиохиндолинов |
| GB8500605D0 (en) | 1985-01-10 | 1985-02-13 | Secretary Trade Ind Brit | Damped spring |
| JPS63238079A (ja) | 1987-03-24 | 1988-10-04 | Masatoshi Yamato | キノリン系化合物、その製造法及びその化合物を有効成分とする抗癌剤 |
| JPH0720867B2 (ja) | 1987-05-26 | 1995-03-08 | キッセイ薬品工業株式会社 | 骨粗鬆症治療剤 |
| MX13270A (es) | 1987-10-05 | 1993-06-01 | Pfizer | Procedimiento para la preparacion de derivados de 4-aminopiridina |
| JPH02256667A (ja) | 1988-12-27 | 1990-10-17 | Masatoshi Yamato | 縮合キノリン系化合物およびその製造方法 |
| US5223506A (en) | 1991-06-04 | 1993-06-29 | Glaxo Inc. | Cyclic antitumor compounds |
| WO1994020869A1 (en) | 1993-03-12 | 1994-09-15 | Ppg Industries, Inc. | Novel benzopyrans |
| US5428040A (en) | 1993-08-31 | 1995-06-27 | The Du Pont Merck Pharmaceutical Company | Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents |
| WO1996010015A1 (en) | 1994-09-28 | 1996-04-04 | Shaman Pharmaceuticals, Inc. | Cryptolepine analogs with hypoglycemic activity |
| EP1043325B1 (en) * | 1994-12-22 | 2004-06-16 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
| KR100263137B1 (ko) | 1995-09-08 | 2000-08-01 | 오테스코그 페르 | 오판 수용체 |
| US5998402A (en) | 1996-04-19 | 1999-12-07 | American Home Products Corporation | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents |
| WO1998045272A1 (en) | 1997-04-07 | 1998-10-15 | Latrobe University | Topoisomerase inhibitors |
| US7157568B1 (en) | 1997-08-05 | 2007-01-02 | American Home Products Corporation | Human estrogen receptor-β |
| US6110962A (en) | 1998-05-12 | 2000-08-29 | American Home Products Corporation | 11-aryl-benzo[B]naphtho[2,3-D]furans and 11-aryl-benzo[B]naphtho[2,3-D]thiophenes useful in the treatment of insulin resistance and hyperglycemia |
| GB9814620D0 (en) | 1998-07-06 | 1998-09-02 | Karobio Ab | Vasculoprotector |
| WO2000059897A2 (en) | 1999-04-06 | 2000-10-12 | Akzo Nobel N.V. | Esters and carbonates of 2-(4-hydroxyphenyl)-6(or 5)-hydroxy-benzothiophene derivatives as selective estrogenic compounds |
| DK1165184T3 (da) | 1999-04-09 | 2004-04-13 | Karobio Ab | Estrogenreceptor-beta antagonisme og knoglesygdomme |
| JP2002542187A (ja) | 1999-04-16 | 2002-12-10 | アストラゼネカ・アクチエボラーグ | エストロゲン−β受容体リガンド |
| GB9913649D0 (en) | 1999-06-11 | 1999-08-11 | Karobio Ab | Estrogen receptor |
| WO2001024785A2 (en) | 1999-10-01 | 2001-04-12 | Institute Of Molecular And Cell Biology | Dihydroorotate dehydrogenase inhibitors for the treatment of viral-mediated diseases |
| AU2001256164A1 (en) | 2000-03-01 | 2001-09-12 | Akzo Nobel N.V. | Chroman derivatives as estrogenic compounds |
| JP2003528858A (ja) | 2000-03-27 | 2003-09-30 | アクゾ・ノベル・エヌ・ベー | エストロゲン関連治療用のノンステロイド系四環式化合物 |
| US7226945B2 (en) | 2000-10-13 | 2007-06-05 | Astrazeneca Ab | Estrogen receptor-β ligands |
| GB2361642A (en) | 2000-10-24 | 2001-10-31 | Karobio Ab | Estrogen receptor beta (ERbeta) agonists for use in cancer treatment |
| WO2002046168A1 (en) | 2000-12-07 | 2002-06-13 | Astrazeneca Ab | Therapeutic benzimidazole compounds |
| WO2002046164A1 (en) | 2000-12-07 | 2002-06-13 | Astrazeneca Ab | Therapeutic compounds |
| WO2002051821A1 (en) | 2000-12-22 | 2002-07-04 | Astrazeneca Ab | Therapeutic compounds |
| JP2004529107A (ja) | 2001-02-27 | 2004-09-24 | シエーリング アクチエンゲゼルシャフト | 受胎能を調節するためのERβ−選択性リガンドの使用及びそのための有用な化合物 |
| JP3562481B2 (ja) | 2001-04-02 | 2004-09-08 | 株式会社村田製作所 | 射出成形方法および射出成形機 |
| GB2374412A (en) | 2001-04-11 | 2002-10-16 | Karobio Ab | Hypertension treatment and assay |
| US6559177B2 (en) | 2001-04-19 | 2003-05-06 | Wyeth | 5, 11-Dioxa-benzo[b]fluoren-10-one and 5-oxa-11-thia-benzo[b]fluoren-10-ones as estrogenic agents |
| US6589980B2 (en) | 2001-05-17 | 2003-07-08 | Wyeth | Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents |
| WO2003044006A1 (en) | 2001-11-19 | 2003-05-30 | Eli Lilly And Company | Substituted benzopyrans as selective estrogen receptor-beta agonists |
| EP1478631A1 (en) | 2001-11-28 | 2004-11-24 | AstraZeneca AB | Therapeutic compounds |
| UA83620C2 (ru) | 2001-12-05 | 2008-08-11 | Уайт | Замещенные бензоксазолы и их аналоги как эстрогенные агенты |
| US6903238B2 (en) | 2001-12-13 | 2005-06-07 | Wyeth | Substituted indenones as estrogenic agents |
| TW200301107A (en) | 2001-12-13 | 2003-07-01 | Wyeth Corp | Substituted 6H-dibenzo[c,h]chromenes as estrogenic agents |
| US6960607B2 (en) | 2001-12-13 | 2005-11-01 | Wyeth | Naphthyl benzoxazoles and benzisoxazoles as estrogenic agents |
| US6835745B2 (en) | 2002-01-15 | 2004-12-28 | Wyeth | Phenyl substituted thiophenes as estrogenic agents |
| WO2003061701A2 (en) | 2002-01-24 | 2003-07-31 | Wyeth | Method of treating hemorrhagic shock or systemic inflammatory response syndrome |
| US20040002524A1 (en) | 2002-06-24 | 2004-01-01 | Richard Chesworth | Benzimidazole compounds and their use as estrogen agonists/antagonists |
| WO2004073610A2 (en) | 2003-02-13 | 2004-09-02 | Merck & Co., Inc. | Estrogen receptor modulators |
| DE602004025460D1 (de) | 2003-04-21 | 2010-03-25 | Lilly Co Eli | Substituierte benzopyrane als selektive antagonisten am östrogenrezeptor-beta |
| ATE406373T1 (de) | 2003-04-21 | 2008-09-15 | Lilly Co Eli | Substituierte benzopyrane als selektive antagonisten am östrogenrezeptor-beta |
| DE10318896A1 (de) | 2003-04-22 | 2004-11-25 | Schering Ag | 8beta-Vinyl-11beta-(omega-substituierte)alkyl-estra-1,3,5(10)-triene |
| US7279600B2 (en) | 2003-05-02 | 2007-10-09 | Wyeth | Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents |
| CL2004000985A1 (es) | 2003-05-16 | 2005-01-14 | Wyeth Corp | Compuestos derivados de fenilquinolinas; composicion farmaceutica, proceso de preparacion; y uso para tratar osteoporosis, enfermedad de paget, dano vascular, osteoartritis, cancer oseo, cancer ovarico, cancer prostatico, hipercolesterolemia, aterosc |
| US7250440B2 (en) | 2003-08-12 | 2007-07-31 | Wyeth | (Hydroxyphenyl)-1H-indole-3-carbaldehyde oxime derivatives as estrogenic agents |
| WO2005051972A1 (en) | 2003-11-24 | 2005-06-09 | Merck & Co., Inc. | Estrogen receptor modulators |
| US7157492B2 (en) | 2004-02-26 | 2007-01-02 | Wyeth | Dibenzo chromene derivatives and their use as ERβ selective ligands |
| AU2005254949A1 (en) | 2004-06-10 | 2005-12-29 | Merck & Co., Inc. | Estrogen receptor modulators |
-
2005
- 2005-09-06 CN CNA2005800379553A patent/CN101052641A/zh active Pending
- 2005-09-06 EP EP05813086A patent/EP1789420A2/en not_active Withdrawn
- 2005-09-06 RU RU2007106870/04A patent/RU2007106870A/ru not_active Application Discontinuation
- 2005-09-06 US US11/219,940 patent/US7354927B2/en not_active Expired - Fee Related
- 2005-09-06 JP JP2007531265A patent/JP2008512458A/ja active Pending
- 2005-09-06 AU AU2005282554A patent/AU2005282554A1/en not_active Abandoned
- 2005-09-06 CA CA002578164A patent/CA2578164A1/en not_active Abandoned
- 2005-09-06 WO PCT/US2005/031696 patent/WO2006029146A2/en not_active Ceased
- 2005-09-06 BR BRPI0514974-6A patent/BRPI0514974A/pt not_active IP Right Cessation
- 2005-09-06 KR KR1020077005450A patent/KR20070061536A/ko not_active Withdrawn
- 2005-09-06 MX MX2007002789A patent/MX2007002789A/es active IP Right Grant
-
2007
- 2007-02-22 IL IL181514A patent/IL181514A0/en unknown
- 2007-03-06 ZA ZA200701950A patent/ZA200701950B/xx unknown
- 2007-03-07 EC EC2007007302A patent/ECSP077302A/es unknown
- 2007-03-14 NO NO20071364A patent/NO20071364L/no not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008512458A5 (https=) | ||
| RU2007106870A (ru) | 6Н-[1]БЕНЗОПИРАНО[4,3-b]ХИНОЛИНЫ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ЭСТРОГЕННЫХ АГЕНТОВ | |
| JP7345581B2 (ja) | Pde4抑制活性を有する化合物の製造方法 | |
| JPH0662580B2 (ja) | N―(アリールオキシアルキル)ヘテロアリールピペリジンおよびn―(アリールオキシアルキル)ヘテロアリールピペラジン | |
| JP6787995B2 (ja) | 細胞毒性ベンゾジアゼピン誘導体の調製方法 | |
| US7232910B2 (en) | Methods of preparing indazole compounds | |
| CN107001286B (zh) | 二氢嘧啶-2-酮化合物和其医药用途 | |
| JP2021513982A (ja) | P300/cbp hat阻害剤及びそれらの使用の方法 | |
| EP2590949A1 (en) | Method for manufacturing of quinoline-3-carboxamides | |
| EP2599774B1 (en) | Condensed pyridine compounds as cb2 cannabinoid receptor ligands | |
| EP2632896A2 (en) | Electrophilic reagents for monohalomethylation,their preparation and their uses | |
| CZ2001433A3 (cs) | Substituované imidazo[1,2a]aziny jako selektivní inhibitory COX-2 | |
| JP2808460B2 (ja) | イミダゾール誘導体 | |
| TWI888947B (zh) | 用於製備可溶性鳥苷酸環化酶刺激劑之新穎方法及中間物 | |
| TW201625537A (zh) | 用於製備3-羥基吡啶甲酸的方法 | |
| JP2026502218A (ja) | Nlrp3インフラマソーム阻害剤の結晶形態、化学的プロセス及び化学化合物 | |
| WO2016101794A1 (zh) | 替唑尼特磷酸酯和烷基磺酸酯及其在药学中的应用 | |
| WO2001030764A1 (en) | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | |
| JP4272271B2 (ja) | ハロゲノ−o−ヒドロキシジフェニル化合物の製造方法 | |
| CN112088003A (zh) | 制备嘧啶基-4-氨基吡唑化合物的工艺 | |
| CN107848968A (zh) | 从乙醛酸制备内酰胺的方法 | |
| TWI603959B (zh) | 嗒酮化合物之製造方法及其中間物之製造方法 | |
| CA2791947A1 (fr) | Derives de 1h-pyrazolo[4,3-c]isoquinoleines, leur preparation et leur application en therapeutique | |
| JP7193557B2 (ja) | 新規な気管支拡張性ヘテロ結合アミド | |
| JP2022517799A (ja) | B型肝炎ウイルス感染症の処置および予防のための置換されたクロメン-4-オン |