JP2008511669A5 - - Google Patents

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Publication number
JP2008511669A5
JP2008511669A5 JP2007530353A JP2007530353A JP2008511669A5 JP 2008511669 A5 JP2008511669 A5 JP 2008511669A5 JP 2007530353 A JP2007530353 A JP 2007530353A JP 2007530353 A JP2007530353 A JP 2007530353A JP 2008511669 A5 JP2008511669 A5 JP 2008511669A5
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JP
Japan
Prior art keywords
methyl
het
cycloalkyl
alkyl
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007530353A
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English (en)
Japanese (ja)
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JP2008511669A (ja
JP2008511669A6 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/031099 external-priority patent/WO2006026703A2/en
Publication of JP2008511669A publication Critical patent/JP2008511669A/ja
Publication of JP2008511669A6 publication Critical patent/JP2008511669A6/ja
Publication of JP2008511669A5 publication Critical patent/JP2008511669A5/ja
Pending legal-status Critical Current

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JP2007530353A 2004-09-02 2005-08-28 化合物 Pending JP2008511669A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US60674204P 2004-09-02 2004-09-02
US60/606,742 2004-09-02
US61076504P 2004-09-17 2004-09-17
US60/610,765 2004-09-17
PCT/US2005/031099 WO2006026703A2 (en) 2004-09-02 2005-08-28 Chemical compounds

Publications (3)

Publication Number Publication Date
JP2008511669A JP2008511669A (ja) 2008-04-17
JP2008511669A6 JP2008511669A6 (ja) 2008-07-31
JP2008511669A5 true JP2008511669A5 (https=) 2008-10-16

Family

ID=36000724

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007530353A Pending JP2008511669A (ja) 2004-09-02 2005-08-28 化合物
JP2007530352A Pending JP2008511668A (ja) 2004-09-02 2005-08-31 化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007530352A Pending JP2008511668A (ja) 2004-09-02 2005-08-31 化合物

Country Status (16)

Country Link
US (2) US20070254910A1 (https=)
EP (2) EP1799671A4 (https=)
JP (2) JP2008511669A (https=)
KR (2) KR20070049682A (https=)
AR (2) AR050302A1 (https=)
AU (2) AU2005279835A1 (https=)
BR (1) BRPI0514881A (https=)
CA (2) CA2578746A1 (https=)
IL (1) IL181419A0 (https=)
MA (1) MA28872B1 (https=)
MX (2) MX2007002679A (https=)
NO (2) NO20071366L (https=)
PE (2) PE20060712A1 (https=)
RU (2) RU2351592C2 (https=)
TW (2) TW200621754A (https=)
WO (2) WO2006026703A2 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008511669A (ja) * 2004-09-02 2008-04-17 スミスクライン ビーチャム コーポレーション 化合物
PE20070946A1 (es) * 2006-01-25 2007-10-16 Smithkline Beecham Corp COMPUESTOS DERIVADOS DE IMIDAZO[1,2-a]PIRIDINA COMO MODULADORES DEL RECEPTOR DE QUIMIOQUINA (CXCR4)
EP2042503B1 (en) 2006-05-16 2013-01-30 Ono Pharmaceutical Co., Ltd. Compound having acidic group which may be protected, and use thereof
WO2008016006A1 (fr) 2006-07-31 2008-02-07 Ono Pharmaceutical Co., Ltd. Composé auquel un groupe cyclique est lié par une liaison spiro et son utilisation
US7767826B2 (en) * 2007-10-05 2010-08-03 Pharmatech International, Inc. Process for the synthesis of L-(+)-ergothioneine
EP2217069A4 (en) * 2007-11-09 2012-03-14 Salk Inst For Biological Studi INHIBITORS OF NON-NUCLEOSIDE INHIBITORS OF THE REVERSE TRANSCRIPTASE
CN102675305B (zh) * 2011-03-08 2014-11-12 中国科学院上海药物研究所 一类咪唑并吡啶类化合物及其制备方法和用途
CN103570683B (zh) * 2012-07-30 2018-04-17 中国科学院上海药物研究所 多取代胺类化合物及其制备方法和用途
MX373103B (es) 2014-02-13 2020-04-17 Incyte Holdings Corp Ciclopropilaminas como inhibidores de desmetilasa específica de lisina 1 (lsd1).
SI3105218T1 (sl) 2014-02-13 2019-11-29 Incyte Corp Ciklopropilamini kot inhibitorji LSD1
WO2016007722A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
EP3277689B1 (en) 2015-04-03 2019-09-04 Incyte Corporation Heterocyclic compounds as lsd1 inhibitors
LT3334709T (lt) 2015-08-12 2025-03-10 Incyte Holdings Corporation Lsd1 inhibitoriaus druskos
WO2017106332A1 (en) 2015-12-14 2017-06-22 X4 Pharmaceuticals, Inc. Methods for treating cancer
CN109069426B (zh) 2015-12-14 2021-10-29 X4 制药有限公司 治疗癌症的方法
KR102738306B1 (ko) * 2015-12-15 2024-12-03 브리스톨-마이어스 스큅 컴퍼니 Cxcr4 수용체 길항제
PL3393468T3 (pl) 2015-12-22 2023-01-23 X4 Pharmaceuticals, Inc. Metody leczenia niedoboru odporności
US11337969B2 (en) 2016-04-08 2022-05-24 X4 Pharmaceuticals, Inc. Methods for treating cancer
WO2017223243A1 (en) 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
CN109640988A (zh) 2016-06-21 2019-04-16 X4 制药有限公司 Cxcr4抑制剂及其用途
ES2870920T3 (es) 2016-06-21 2021-10-28 X4 Pharmaceuticals Inc Inhibidores de CXCR4 y usos de los mismos
EP3585387A4 (en) 2017-02-21 2020-08-12 Emory University CHEMIOKIN CXCR4 RECEIVER MODULATORS AND THEIR USES
JP7282786B2 (ja) * 2017-09-25 2023-05-29 シージーンテック (スーチョウ, チャイナ) カンパニー リミテッド Cxcr4阻害剤としてのヘテロアリール化合物、それを用いた組成物及び方法
KR102678977B1 (ko) * 2017-09-25 2024-06-28 씨젠테크 (쑤저우, 차이나) 컴퍼니 리미티드 Cxcr4 저해제로서 헤테로아릴 화합물, 그 조성물 및 이용 방법
US11649235B2 (en) 2018-03-19 2023-05-16 Emory University Pan-tropic entry inhibitors
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
WO2020047198A1 (en) 2018-08-31 2020-03-05 Incyte Corporation Salts of an lsd1 inhibitor and processes for preparing the same
CA3171250A1 (en) 2020-03-10 2021-09-16 E. Lynne KELLEY Methods for treating neutropenia

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
JP2004512336A (ja) * 2000-09-15 2004-04-22 アノーメッド インコーポレイティド ケモカインレセプター結合複素環式化合物
PT1317451E (pt) * 2000-09-15 2006-12-29 Anormed Inc Compostos heterocíclicos que se ligam a receptores de quimioquinas
US6835731B2 (en) * 2000-09-15 2004-12-28 Anormed, Inc. Chemokine receptor binding heterocyclic compounds
CA2419224A1 (en) * 2000-09-15 2002-03-21 Anormed Inc. Chemokine receptor binding heterocyclic compounds
CA2467718C (en) * 2001-12-21 2011-04-26 Anormed Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
EP1613613B1 (en) * 2003-04-11 2021-06-02 Genzyme Corporation Cxcr4 chemokine receptor binding compounds
JP2008511669A (ja) * 2004-09-02 2008-04-17 スミスクライン ビーチャム コーポレーション 化合物
WO2006036816A2 (en) * 2004-09-24 2006-04-06 Smithkline Beecham Corporation Chemical compounds
EP1919872A4 (en) * 2005-08-31 2009-08-05 Smithkline Beecham Corp CHEMICAL COMPOUNDS

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