JP2008511669A5 - - Google Patents
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- Publication number
- JP2008511669A5 JP2008511669A5 JP2007530353A JP2007530353A JP2008511669A5 JP 2008511669 A5 JP2008511669 A5 JP 2008511669A5 JP 2007530353 A JP2007530353 A JP 2007530353A JP 2007530353 A JP2007530353 A JP 2007530353A JP 2008511669 A5 JP2008511669 A5 JP 2008511669A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- het
- cycloalkyl
- alkyl
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 *N(Cc1c[n]2c(N3CCN(*)CC3)cccc2n1)[C@@]1c2ncccc2CCC1 Chemical compound *N(Cc1c[n]2c(N3CCN(*)CC3)cccc2n1)[C@@]1c2ncccc2CCC1 0.000 description 2
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60674204P | 2004-09-02 | 2004-09-02 | |
| US60/606,742 | 2004-09-02 | ||
| US61076504P | 2004-09-17 | 2004-09-17 | |
| US60/610,765 | 2004-09-17 | ||
| PCT/US2005/031099 WO2006026703A2 (en) | 2004-09-02 | 2005-08-28 | Chemical compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008511669A JP2008511669A (ja) | 2008-04-17 |
| JP2008511669A6 JP2008511669A6 (ja) | 2008-07-31 |
| JP2008511669A5 true JP2008511669A5 (https=) | 2008-10-16 |
Family
ID=36000724
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007530353A Pending JP2008511669A (ja) | 2004-09-02 | 2005-08-28 | 化合物 |
| JP2007530352A Pending JP2008511668A (ja) | 2004-09-02 | 2005-08-31 | 化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007530352A Pending JP2008511668A (ja) | 2004-09-02 | 2005-08-31 | 化合物 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20070232615A1 (https=) |
| EP (2) | EP1799671A4 (https=) |
| JP (2) | JP2008511669A (https=) |
| KR (2) | KR20070053313A (https=) |
| AR (2) | AR051565A1 (https=) |
| AU (2) | AU2005279835A1 (https=) |
| BR (1) | BRPI0514881A (https=) |
| CA (2) | CA2578746A1 (https=) |
| IL (1) | IL181419A0 (https=) |
| MA (1) | MA28872B1 (https=) |
| MX (2) | MX2007002679A (https=) |
| NO (2) | NO20071366L (https=) |
| PE (2) | PE20060656A1 (https=) |
| RU (2) | RU2352567C2 (https=) |
| TW (2) | TW200621754A (https=) |
| WO (2) | WO2006026703A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007002679A (es) * | 2004-09-02 | 2007-05-16 | Smithkline Beecham Corp | Compuestos quimicos. |
| PE20070946A1 (es) * | 2006-01-25 | 2007-10-16 | Smithkline Beecham Corp | COMPUESTOS DERIVADOS DE IMIDAZO[1,2-a]PIRIDINA COMO MODULADORES DEL RECEPTOR DE QUIMIOQUINA (CXCR4) |
| WO2007132846A1 (ja) | 2006-05-16 | 2007-11-22 | Ono Pharmaceutical Co., Ltd. | 保護されていてもよい酸性基を含有する化合物およびその用途 |
| JP5245827B2 (ja) | 2006-07-31 | 2013-07-24 | 小野薬品工業株式会社 | スピロ結合した環状基を含有する化合物およびその用途 |
| US7767826B2 (en) * | 2007-10-05 | 2010-08-03 | Pharmatech International, Inc. | Process for the synthesis of L-(+)-ergothioneine |
| EP2217069A4 (en) * | 2007-11-09 | 2012-03-14 | Salk Inst For Biological Studi | INHIBITORS OF NON-NUCLEOSIDE INHIBITORS OF THE REVERSE TRANSCRIPTASE |
| CN102675305B (zh) * | 2011-03-08 | 2014-11-12 | 中国科学院上海药物研究所 | 一类咪唑并吡啶类化合物及其制备方法和用途 |
| CN103570683B (zh) * | 2012-07-30 | 2018-04-17 | 中国科学院上海药物研究所 | 多取代胺类化合物及其制备方法和用途 |
| JP6602779B2 (ja) | 2014-02-13 | 2019-11-06 | インサイト・コーポレイション | Lsd1阻害剤としてのシクロプロピルアミン類 |
| EP3105218B1 (en) | 2014-02-13 | 2019-09-25 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
| US9695167B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors |
| EP3277689B1 (en) * | 2015-04-03 | 2019-09-04 | Incyte Corporation | Heterocyclic compounds as lsd1 inhibitors |
| MY189367A (en) | 2015-08-12 | 2022-02-08 | Incyte Corp | Salts of an lsd1 inhibitor |
| CA3008279A1 (en) | 2015-12-14 | 2017-06-22 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| CN109069426B (zh) | 2015-12-14 | 2021-10-29 | X4 制药有限公司 | 治疗癌症的方法 |
| JP6856648B2 (ja) * | 2015-12-15 | 2021-04-07 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | Cxcr4受容体アンタゴニスト |
| WO2017112894A1 (en) | 2015-12-22 | 2017-06-29 | X4 Pharmaceuticals, Inc. | Methods for treating immunodeficiency disease |
| CA3019394A1 (en) | 2016-04-08 | 2017-10-12 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| EP3472129A4 (en) | 2016-06-21 | 2019-12-04 | X4 Pharmaceuticals, Inc. | CXCR4 INHIBITORS AND USES THEREOF |
| CN109640988A (zh) | 2016-06-21 | 2019-04-16 | X4 制药有限公司 | Cxcr4抑制剂及其用途 |
| ES2870920T3 (es) | 2016-06-21 | 2021-10-28 | X4 Pharmaceuticals Inc | Inhibidores de CXCR4 y usos de los mismos |
| AU2018225556A1 (en) | 2017-02-21 | 2019-10-03 | Emory University | Chemokine CXCR4 receptor modulators and uses related thereto |
| JP7282786B2 (ja) * | 2017-09-25 | 2023-05-29 | シージーンテック (スーチョウ, チャイナ) カンパニー リミテッド | Cxcr4阻害剤としてのヘテロアリール化合物、それを用いた組成物及び方法 |
| WO2019060860A1 (en) * | 2017-09-25 | 2019-03-28 | Suzhou Yunxuan Yiyao Keji Youxian Gongsi | HETEROARYL COMPOUNDS AS INHIBITORS OF CXCR4, COMPOSITION AND METHOD OF USE THEREOF |
| US11649235B2 (en) | 2018-03-19 | 2023-05-16 | Emory University | Pan-tropic entry inhibitors |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| CA3171250A1 (en) | 2020-03-10 | 2021-09-16 | E. Lynne KELLEY | Methods for treating neutropenia |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ225152A (en) * | 1987-07-17 | 1990-04-26 | Janssen Pharmaceutica Nv | Heterocyclically substituted piperidinyl benzamides as pharmaceuticals |
| US6734191B2 (en) * | 2000-09-15 | 2004-05-11 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| HK1052011A1 (zh) * | 2000-09-15 | 2003-08-29 | Anormed Inc. | 趋化因子受体结合杂环化合物 |
| JP2004512336A (ja) * | 2000-09-15 | 2004-04-22 | アノーメッド インコーポレイティド | ケモカインレセプター結合複素環式化合物 |
| DE60137435D1 (de) * | 2000-09-15 | 2009-03-05 | Anormed Inc | Chemokin rezeptor bindenden heterozyklische verbindungen |
| PL369856A1 (en) * | 2001-12-21 | 2005-05-02 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| WO2004091518A2 (en) * | 2003-04-11 | 2004-10-28 | Anormed Inc. | Cxcr4 chemokine receptor binding compounds |
| MX2007002679A (es) * | 2004-09-02 | 2007-05-16 | Smithkline Beecham Corp | Compuestos quimicos. |
| WO2006036816A2 (en) * | 2004-09-24 | 2006-04-06 | Smithkline Beecham Corporation | Chemical compounds |
| JP2009507795A (ja) * | 2005-08-31 | 2009-02-26 | スミスクライン ビーチャム コーポレーション | 化合物 |
-
2005
- 2005-08-28 MX MX2007002679A patent/MX2007002679A/es not_active Application Discontinuation
- 2005-08-28 JP JP2007530353A patent/JP2008511669A/ja active Pending
- 2005-08-28 WO PCT/US2005/031099 patent/WO2006026703A2/en not_active Ceased
- 2005-08-28 EP EP05815072A patent/EP1799671A4/en not_active Withdrawn
- 2005-08-31 CA CA002578746A patent/CA2578746A1/en not_active Abandoned
- 2005-08-31 BR BRPI0514881-2A patent/BRPI0514881A/pt not_active IP Right Cessation
- 2005-08-31 KR KR1020077007549A patent/KR20070053313A/ko not_active Withdrawn
- 2005-08-31 RU RU2007106780/04A patent/RU2352567C2/ru not_active IP Right Cessation
- 2005-08-31 RU RU2007106779/04A patent/RU2351592C2/ru not_active IP Right Cessation
- 2005-08-31 EP EP05794929A patent/EP1784185A4/en not_active Withdrawn
- 2005-08-31 WO PCT/US2005/031098 patent/WO2006028896A2/en not_active Ceased
- 2005-08-31 US US11/574,583 patent/US20070232615A1/en not_active Abandoned
- 2005-08-31 AU AU2005279835A patent/AU2005279835A1/en not_active Abandoned
- 2005-08-31 CA CA002579059A patent/CA2579059A1/en not_active Abandoned
- 2005-08-31 MX MX2007002615A patent/MX2007002615A/es not_active Application Discontinuation
- 2005-08-31 JP JP2007530352A patent/JP2008511668A/ja active Pending
- 2005-08-31 KR KR1020077007349A patent/KR20070049682A/ko not_active Withdrawn
- 2005-08-31 US US11/574,586 patent/US20070254910A1/en not_active Abandoned
- 2005-08-31 AU AU2005282753A patent/AU2005282753A1/en not_active Abandoned
- 2005-09-01 AR ARP050103666A patent/AR051565A1/es not_active Application Discontinuation
- 2005-09-01 PE PE2005001008A patent/PE20060656A1/es not_active Application Discontinuation
- 2005-09-01 PE PE2005001007A patent/PE20060712A1/es not_active Application Discontinuation
- 2005-09-01 AR ARP050103665A patent/AR050302A1/es not_active Application Discontinuation
- 2005-09-02 TW TW094130018A patent/TW200621754A/zh unknown
- 2005-09-02 TW TW094130013A patent/TW200612921A/zh unknown
-
2007
- 2007-02-19 IL IL181419A patent/IL181419A0/en unknown
- 2007-03-14 NO NO20071366A patent/NO20071366L/no not_active Application Discontinuation
- 2007-03-15 NO NO20071418A patent/NO20071418L/no not_active Application Discontinuation
- 2007-03-23 MA MA29772A patent/MA28872B1/fr unknown
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