JP2008510693A - アレーンルテニウム(ii)化合物及び癌の治療におけるそれらの使用 - Google Patents

アレーンルテニウム(ii)化合物及び癌の治療におけるそれらの使用 Download PDF

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Publication number
JP2008510693A
JP2008510693A JP2007526570A JP2007526570A JP2008510693A JP 2008510693 A JP2008510693 A JP 2008510693A JP 2007526570 A JP2007526570 A JP 2007526570A JP 2007526570 A JP2007526570 A JP 2007526570A JP 2008510693 A JP2008510693 A JP 2008510693A
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Japan
Prior art keywords
compound
compound according
alkyl
group
ligand
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JP2007526570A
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Japanese (ja)
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JP2008510693A5 (https=
Inventor
ハブテマリアン,エイブラハ
サドラー,ピーター,ジョン
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ザ ユニバーシティ コート オブ ザ ユニバーシティ オブ エジンバラ
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Application filed by ザ ユニバーシティ コート オブ ザ ユニバーシティ オブ エジンバラ filed Critical ザ ユニバーシティ コート オブ ザ ユニバーシティ オブ エジンバラ
Publication of JP2008510693A publication Critical patent/JP2008510693A/ja
Publication of JP2008510693A5 publication Critical patent/JP2008510693A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046Ruthenium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2007526570A 2004-08-20 2005-08-19 アレーンルテニウム(ii)化合物及び癌の治療におけるそれらの使用 Pending JP2008510693A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0418643.3A GB0418643D0 (en) 2004-08-20 2004-08-20 Ruthenium (II) compounds
PCT/GB2005/003242 WO2006018649A1 (en) 2004-08-20 2005-08-19 Arene ruthenium (ii) compounds and their use in cancer therapy

Publications (2)

Publication Number Publication Date
JP2008510693A true JP2008510693A (ja) 2008-04-10
JP2008510693A5 JP2008510693A5 (https=) 2008-09-25

Family

ID=33042406

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007526570A Pending JP2008510693A (ja) 2004-08-20 2005-08-19 アレーンルテニウム(ii)化合物及び癌の治療におけるそれらの使用

Country Status (12)

Country Link
EP (1) EP1786412A1 (https=)
JP (1) JP2008510693A (https=)
KR (1) KR20070060091A (https=)
CN (1) CN101043885A (https=)
AU (1) AU2005273726A1 (https=)
BR (1) BRPI0514430A (https=)
CA (1) CA2578280A1 (https=)
GB (1) GB0418643D0 (https=)
MX (1) MX2007002099A (https=)
NO (1) NO20071481L (https=)
WO (1) WO2006018649A1 (https=)
ZA (1) ZA200702093B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010531976A (ja) * 2007-06-19 2010-09-30 オックスフォード バイオセンサーズ リミテッド 酸化還元メディエーター

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006017594A1 (de) * 2006-04-13 2007-10-18 Wacker Chemie Ag Neuartige Ru-Komplexe, deren Herstellung und Verwendung
US9018199B2 (en) 2006-05-09 2015-04-28 Ecole Polytechnique Federale De Lausanne (Epfl) Transition metal complexes for inhibiting resistance in the treatment of cancer and metastasis
EP2067771A1 (en) 2007-12-03 2009-06-10 EPFL Ecole Polytechnique Fédérale de Lausanne Derivatives of Dihydroxypyrrolidine as Anti-Cancer Compounds
EP2409697A1 (en) 2010-07-20 2012-01-25 Université de Neuchâtel Medicaments Based on Dinuclear Ruthenium, Osmium and Iron Complexes Comprising Triply Bridging Thiolato, Selenolato, Alkoxo and/or Amido Ligands
WO2013038395A1 (en) 2011-09-16 2013-03-21 Universidade De Lisboa Transition metal complexes for pharmaceutical applications
WO2013136296A2 (en) 2012-03-14 2013-09-19 Universidade De Lisboa Water-soluble organometallic ruthenium and iron compunds presenting heteroaromatic ligands
BR112015023568B8 (pt) 2013-03-15 2024-01-02 Ann Mcfarland Sherri Composto à base de metal como composto fotodinâmico
US9751081B2 (en) 2014-12-01 2017-09-05 Clemson University Self-regenerating antioxidant catalysts and methods of using the same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19736152A1 (de) * 1997-08-14 1999-02-18 Martin Wehlan Azido-Aziridinkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung
WO2004005304A1 (en) * 2002-07-05 2004-01-15 The University Court, The University Of Edinburgh Ruthenium anticancer complexes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003512471A (ja) * 1999-10-27 2003-04-02 ユニバーシティ コート, エディンバラ大学 窒素および配位子を含む癌治療用の半サンドイッチ状ルテニウム(ii)化合物
GB0016052D0 (en) * 2000-06-30 2000-08-23 Univ Edinburgh Ruthenium (II) compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19736152A1 (de) * 1997-08-14 1999-02-18 Martin Wehlan Azido-Aziridinkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung
WO2004005304A1 (en) * 2002-07-05 2004-01-15 The University Court, The University Of Edinburgh Ruthenium anticancer complexes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010531976A (ja) * 2007-06-19 2010-09-30 オックスフォード バイオセンサーズ リミテッド 酸化還元メディエーター

Also Published As

Publication number Publication date
KR20070060091A (ko) 2007-06-12
GB0418643D0 (en) 2004-09-22
CA2578280A1 (en) 2006-02-23
MX2007002099A (es) 2007-04-24
WO2006018649A1 (en) 2006-02-23
EP1786412A1 (en) 2007-05-23
NO20071481L (no) 2007-05-16
CN101043885A (zh) 2007-09-26
BRPI0514430A (pt) 2008-05-06
ZA200702093B (en) 2008-08-27
AU2005273726A1 (en) 2006-02-23

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