KR20070060091A - 아렌 루테늄(ⅱ) 화합물 및 암 요법에서의 그 용도 - Google Patents

아렌 루테늄(ⅱ) 화합물 및 암 요법에서의 그 용도 Download PDF

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Publication number
KR20070060091A
KR20070060091A KR1020077006364A KR20077006364A KR20070060091A KR 20070060091 A KR20070060091 A KR 20070060091A KR 1020077006364 A KR1020077006364 A KR 1020077006364A KR 20077006364 A KR20077006364 A KR 20077006364A KR 20070060091 A KR20070060091 A KR 20070060091A
Authority
KR
South Korea
Prior art keywords
compound
prodrug
solvate
alkyl
carbocyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020077006364A
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English (en)
Korean (ko)
Inventor
아브라하 해브테마리엄
피터 존 새들러
Original Assignee
유니버시티 오브 코트 오브 더 유니버시티 오브 에딘버그
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 유니버시티 오브 코트 오브 더 유니버시티 오브 에딘버그 filed Critical 유니버시티 오브 코트 오브 더 유니버시티 오브 에딘버그
Publication of KR20070060091A publication Critical patent/KR20070060091A/ko
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020077006364A 2004-08-20 2005-08-19 아렌 루테늄(ⅱ) 화합물 및 암 요법에서의 그 용도 Withdrawn KR20070060091A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0418643.3 2004-08-20
GBGB0418643.3A GB0418643D0 (en) 2004-08-20 2004-08-20 Ruthenium (II) compounds

Publications (1)

Publication Number Publication Date
KR20070060091A true KR20070060091A (ko) 2007-06-12

Family

ID=33042406

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077006364A Withdrawn KR20070060091A (ko) 2004-08-20 2005-08-19 아렌 루테늄(ⅱ) 화합물 및 암 요법에서의 그 용도

Country Status (12)

Country Link
EP (1) EP1786412A1 (https=)
JP (1) JP2008510693A (https=)
KR (1) KR20070060091A (https=)
CN (1) CN101043885A (https=)
AU (1) AU2005273726A1 (https=)
BR (1) BRPI0514430A (https=)
CA (1) CA2578280A1 (https=)
GB (1) GB0418643D0 (https=)
MX (1) MX2007002099A (https=)
NO (1) NO20071481L (https=)
WO (1) WO2006018649A1 (https=)
ZA (1) ZA200702093B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006017594A1 (de) * 2006-04-13 2007-10-18 Wacker Chemie Ag Neuartige Ru-Komplexe, deren Herstellung und Verwendung
US9018199B2 (en) 2006-05-09 2015-04-28 Ecole Polytechnique Federale De Lausanne (Epfl) Transition metal complexes for inhibiting resistance in the treatment of cancer and metastasis
GB0711849D0 (en) * 2007-06-19 2007-07-25 Oxford Biosensors Ltd Redox Mediators
EP2067771A1 (en) 2007-12-03 2009-06-10 EPFL Ecole Polytechnique Fédérale de Lausanne Derivatives of Dihydroxypyrrolidine as Anti-Cancer Compounds
EP2409697A1 (en) 2010-07-20 2012-01-25 Université de Neuchâtel Medicaments Based on Dinuclear Ruthenium, Osmium and Iron Complexes Comprising Triply Bridging Thiolato, Selenolato, Alkoxo and/or Amido Ligands
WO2013038395A1 (en) 2011-09-16 2013-03-21 Universidade De Lisboa Transition metal complexes for pharmaceutical applications
WO2013136296A2 (en) 2012-03-14 2013-09-19 Universidade De Lisboa Water-soluble organometallic ruthenium and iron compunds presenting heteroaromatic ligands
BR112015023568B8 (pt) 2013-03-15 2024-01-02 Ann Mcfarland Sherri Composto à base de metal como composto fotodinâmico
US9751081B2 (en) 2014-12-01 2017-09-05 Clemson University Self-regenerating antioxidant catalysts and methods of using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19736152A1 (de) * 1997-08-14 1999-02-18 Martin Wehlan Azido-Aziridinkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung
JP2003512471A (ja) * 1999-10-27 2003-04-02 ユニバーシティ コート， エディンバラ大学 窒素および配位子を含む癌治療用の半サンドイッチ状ルテニウム（ｉｉ）化合物
GB0016052D0 (en) * 2000-06-30 2000-08-23 Univ Edinburgh Ruthenium (II) compounds
GB0215526D0 (en) * 2002-07-05 2002-08-14 Univ Edinburgh Anticancer compounds

Also Published As

Publication number Publication date
GB0418643D0 (en) 2004-09-22
CA2578280A1 (en) 2006-02-23
MX2007002099A (es) 2007-04-24
WO2006018649A1 (en) 2006-02-23
EP1786412A1 (en) 2007-05-23
NO20071481L (no) 2007-05-16
CN101043885A (zh) 2007-09-26
JP2008510693A (ja) 2008-04-10
BRPI0514430A (pt) 2008-05-06
ZA200702093B (en) 2008-08-27
AU2005273726A1 (en) 2006-02-23

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20070320

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid