CN101043885A - 芳烃钌(ⅱ)化合物及其在癌症治疗中的用途 - Google Patents

芳烃钌(ⅱ)化合物及其在癌症治疗中的用途 Download PDF

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Publication number
CN101043885A
CN101043885A CNA2005800355417A CN200580035541A CN101043885A CN 101043885 A CN101043885 A CN 101043885A CN A2005800355417 A CNA2005800355417 A CN A2005800355417A CN 200580035541 A CN200580035541 A CN 200580035541A CN 101043885 A CN101043885 A CN 101043885A
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CN
China
Prior art keywords
group
compound according
sup
alkyl
carbocyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800355417A
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English (en)
Chinese (zh)
Inventor
A·哈布特马里亚姆
P·J·萨德勒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Edinburgh
Original Assignee
University of Edinburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by University of Edinburgh filed Critical University of Edinburgh
Publication of CN101043885A publication Critical patent/CN101043885A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CNA2005800355417A 2004-08-20 2005-08-19 芳烃钌(ⅱ)化合物及其在癌症治疗中的用途 Pending CN101043885A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0418643.3 2004-08-20
GBGB0418643.3A GB0418643D0 (en) 2004-08-20 2004-08-20 Ruthenium (II) compounds

Publications (1)

Publication Number Publication Date
CN101043885A true CN101043885A (zh) 2007-09-26

Family

ID=33042406

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800355417A Pending CN101043885A (zh) 2004-08-20 2005-08-19 芳烃钌(ⅱ)化合物及其在癌症治疗中的用途

Country Status (12)

Country Link
EP (1) EP1786412A1 (https=)
JP (1) JP2008510693A (https=)
KR (1) KR20070060091A (https=)
CN (1) CN101043885A (https=)
AU (1) AU2005273726A1 (https=)
BR (1) BRPI0514430A (https=)
CA (1) CA2578280A1 (https=)
GB (1) GB0418643D0 (https=)
MX (1) MX2007002099A (https=)
NO (1) NO20071481L (https=)
WO (1) WO2006018649A1 (https=)
ZA (1) ZA200702093B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006017594A1 (de) * 2006-04-13 2007-10-18 Wacker Chemie Ag Neuartige Ru-Komplexe, deren Herstellung und Verwendung
US9018199B2 (en) 2006-05-09 2015-04-28 Ecole Polytechnique Federale De Lausanne (Epfl) Transition metal complexes for inhibiting resistance in the treatment of cancer and metastasis
GB0711849D0 (en) * 2007-06-19 2007-07-25 Oxford Biosensors Ltd Redox Mediators
EP2067771A1 (en) 2007-12-03 2009-06-10 EPFL Ecole Polytechnique Fédérale de Lausanne Derivatives of Dihydroxypyrrolidine as Anti-Cancer Compounds
EP2409697A1 (en) 2010-07-20 2012-01-25 Université de Neuchâtel Medicaments Based on Dinuclear Ruthenium, Osmium and Iron Complexes Comprising Triply Bridging Thiolato, Selenolato, Alkoxo and/or Amido Ligands
WO2013038395A1 (en) 2011-09-16 2013-03-21 Universidade De Lisboa Transition metal complexes for pharmaceutical applications
WO2013136296A2 (en) 2012-03-14 2013-09-19 Universidade De Lisboa Water-soluble organometallic ruthenium and iron compunds presenting heteroaromatic ligands
BR112015023568B8 (pt) 2013-03-15 2024-01-02 Ann Mcfarland Sherri Composto à base de metal como composto fotodinâmico
US9751081B2 (en) 2014-12-01 2017-09-05 Clemson University Self-regenerating antioxidant catalysts and methods of using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19736152A1 (de) * 1997-08-14 1999-02-18 Martin Wehlan Azido-Aziridinkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung
JP2003512471A (ja) * 1999-10-27 2003-04-02 ユニバーシティ コート， エディンバラ大学 窒素および配位子を含む癌治療用の半サンドイッチ状ルテニウム（ｉｉ）化合物
GB0016052D0 (en) * 2000-06-30 2000-08-23 Univ Edinburgh Ruthenium (II) compounds
GB0215526D0 (en) * 2002-07-05 2002-08-14 Univ Edinburgh Anticancer compounds

Also Published As

Publication number Publication date
KR20070060091A (ko) 2007-06-12
GB0418643D0 (en) 2004-09-22
CA2578280A1 (en) 2006-02-23
MX2007002099A (es) 2007-04-24
WO2006018649A1 (en) 2006-02-23
EP1786412A1 (en) 2007-05-23
NO20071481L (no) 2007-05-16
JP2008510693A (ja) 2008-04-10
BRPI0514430A (pt) 2008-05-06
ZA200702093B (en) 2008-08-27
AU2005273726A1 (en) 2006-02-23

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Open date: 20070926