AU2005273726A1 - Arene ruthenium (II) compounds and their use in cancer therapy - Google Patents

Arene ruthenium (II) compounds and their use in cancer therapy Download PDF

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Publication number
AU2005273726A1
AU2005273726A1 AU2005273726A AU2005273726A AU2005273726A1 AU 2005273726 A1 AU2005273726 A1 AU 2005273726A1 AU 2005273726 A AU2005273726 A AU 2005273726A AU 2005273726 A AU2005273726 A AU 2005273726A AU 2005273726 A1 AU2005273726 A1 AU 2005273726A1
Authority
AU
Australia
Prior art keywords
compound according
alkyl
carbocyclic
compound
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2005273726A
Other languages
English (en)
Inventor
Abraha Habtemariam
Peter John Sadler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Edinburgh
Original Assignee
University of Edinburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Edinburgh filed Critical University of Edinburgh
Publication of AU2005273726A1 publication Critical patent/AU2005273726A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046Ruthenium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2005273726A 2004-08-20 2005-08-19 Arene ruthenium (II) compounds and their use in cancer therapy Abandoned AU2005273726A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0418643.3 2004-08-20
GBGB0418643.3A GB0418643D0 (en) 2004-08-20 2004-08-20 Ruthenium (II) compounds
PCT/GB2005/003242 WO2006018649A1 (en) 2004-08-20 2005-08-19 Arene ruthenium (ii) compounds and their use in cancer therapy

Publications (1)

Publication Number Publication Date
AU2005273726A1 true AU2005273726A1 (en) 2006-02-23

Family

ID=33042406

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005273726A Abandoned AU2005273726A1 (en) 2004-08-20 2005-08-19 Arene ruthenium (II) compounds and their use in cancer therapy

Country Status (12)

Country Link
EP (1) EP1786412A1 (https=)
JP (1) JP2008510693A (https=)
KR (1) KR20070060091A (https=)
CN (1) CN101043885A (https=)
AU (1) AU2005273726A1 (https=)
BR (1) BRPI0514430A (https=)
CA (1) CA2578280A1 (https=)
GB (1) GB0418643D0 (https=)
MX (1) MX2007002099A (https=)
NO (1) NO20071481L (https=)
WO (1) WO2006018649A1 (https=)
ZA (1) ZA200702093B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006017594A1 (de) * 2006-04-13 2007-10-18 Wacker Chemie Ag Neuartige Ru-Komplexe, deren Herstellung und Verwendung
US9018199B2 (en) 2006-05-09 2015-04-28 Ecole Polytechnique Federale De Lausanne (Epfl) Transition metal complexes for inhibiting resistance in the treatment of cancer and metastasis
GB0711849D0 (en) * 2007-06-19 2007-07-25 Oxford Biosensors Ltd Redox Mediators
EP2067771A1 (en) 2007-12-03 2009-06-10 EPFL Ecole Polytechnique Fédérale de Lausanne Derivatives of Dihydroxypyrrolidine as Anti-Cancer Compounds
EP2409697A1 (en) 2010-07-20 2012-01-25 Université de Neuchâtel Medicaments Based on Dinuclear Ruthenium, Osmium and Iron Complexes Comprising Triply Bridging Thiolato, Selenolato, Alkoxo and/or Amido Ligands
WO2013038395A1 (en) 2011-09-16 2013-03-21 Universidade De Lisboa Transition metal complexes for pharmaceutical applications
WO2013136296A2 (en) 2012-03-14 2013-09-19 Universidade De Lisboa Water-soluble organometallic ruthenium and iron compunds presenting heteroaromatic ligands
BR112015023568B8 (pt) 2013-03-15 2024-01-02 Ann Mcfarland Sherri Composto à base de metal como composto fotodinâmico
US9751081B2 (en) 2014-12-01 2017-09-05 Clemson University Self-regenerating antioxidant catalysts and methods of using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19736152A1 (de) * 1997-08-14 1999-02-18 Martin Wehlan Azido-Aziridinkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung
JP2003512471A (ja) * 1999-10-27 2003-04-02 ユニバーシティ コート, エディンバラ大学 窒素および配位子を含む癌治療用の半サンドイッチ状ルテニウム(ii)化合物
GB0016052D0 (en) * 2000-06-30 2000-08-23 Univ Edinburgh Ruthenium (II) compounds
GB0215526D0 (en) * 2002-07-05 2002-08-14 Univ Edinburgh Anticancer compounds

Also Published As

Publication number Publication date
KR20070060091A (ko) 2007-06-12
GB0418643D0 (en) 2004-09-22
CA2578280A1 (en) 2006-02-23
MX2007002099A (es) 2007-04-24
WO2006018649A1 (en) 2006-02-23
EP1786412A1 (en) 2007-05-23
NO20071481L (no) 2007-05-16
CN101043885A (zh) 2007-09-26
JP2008510693A (ja) 2008-04-10
BRPI0514430A (pt) 2008-05-06
ZA200702093B (en) 2008-08-27

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application