NO20071481L - Aren-ruthenium (II)-forbindelser og deres anvendelse i kreftterapi - Google Patents
Aren-ruthenium (II)-forbindelser og deres anvendelse i kreftterapiInfo
- Publication number
- NO20071481L NO20071481L NO20071481A NO20071481A NO20071481L NO 20071481 L NO20071481 L NO 20071481L NO 20071481 A NO20071481 A NO 20071481A NO 20071481 A NO20071481 A NO 20071481A NO 20071481 L NO20071481 L NO 20071481L
- Authority
- NO
- Norway
- Prior art keywords
- donor
- carbocyclic
- ruthenium
- aren
- compounds
- Prior art date
Links
- 238000011275 oncology therapy Methods 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- 125000002837 carbocyclic group Chemical group 0.000 abstract 3
- 239000003446 ligand Substances 0.000 abstract 2
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
- 125000003627 8 membered carbocyclic group Chemical group 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- -1 ruthenium (II) compound Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0046—Ruthenium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
En rutenium (II) forbindelse ifølge formel (1):. eller et solvat eller promedikament derav, hvor,,, R, Rog Rvelges uavhengig fra H, C-yalkyl, C.aryl, C.heterosyklyl, halo, ester, amido, acyl, sulfo, sulfonamido, eter, tioeter, azo, amino, eller Rog Rdanner sammen med ringen som de er knyttet til, en mettet eller umettet karbosyklisk eller heterosyklisk gruppe som inneholder opptil tre 3- til 8- leddede karbosykliske eller heterosykliske ringer, hvor hver enkelt karbosyklisk eller heterosyklisk ring kan sammenslåes til en eller flere andre karbosykliske eller heterosykliske ringer; X er en nøytral eller negativt ladet N- eller S- donorligand; Y er et motion; m er 0 eller 1; q er 1, 2 eller 3; C er C_alkylen bundet til A-grupper; p er 0 eller 1 og r er 1 når p er 0 og r er 2 når p er 1; og A og B er hver uavhengige O-donor-, N-donor- eller S-donorligander, og kan bindes sammen med hverandre.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0418643.3A GB0418643D0 (en) | 2004-08-20 | 2004-08-20 | Ruthenium (II) compounds |
| PCT/GB2005/003242 WO2006018649A1 (en) | 2004-08-20 | 2005-08-19 | Arene ruthenium (ii) compounds and their use in cancer therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20071481L true NO20071481L (no) | 2007-05-16 |
Family
ID=33042406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20071481A NO20071481L (no) | 2004-08-20 | 2007-03-20 | Aren-ruthenium (II)-forbindelser og deres anvendelse i kreftterapi |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1786412A1 (no) |
| JP (1) | JP2008510693A (no) |
| KR (1) | KR20070060091A (no) |
| CN (1) | CN101043885A (no) |
| AU (1) | AU2005273726A1 (no) |
| BR (1) | BRPI0514430A (no) |
| CA (1) | CA2578280A1 (no) |
| GB (1) | GB0418643D0 (no) |
| MX (1) | MX2007002099A (no) |
| NO (1) | NO20071481L (no) |
| WO (1) | WO2006018649A1 (no) |
| ZA (1) | ZA200702093B (no) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006017594A1 (de) | 2006-04-13 | 2007-10-18 | Wacker Chemie Ag | Neuartige Ru-Komplexe, deren Herstellung und Verwendung |
| EP2016085B9 (en) | 2006-05-09 | 2015-12-30 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Transition metal complexes for inhibiting resistance in the treatment of cancer and metastasis |
| GB0711849D0 (en) | 2007-06-19 | 2007-07-25 | Oxford Biosensors Ltd | Redox Mediators |
| EP2067771A1 (en) | 2007-12-03 | 2009-06-10 | EPFL Ecole Polytechnique Fédérale de Lausanne | Derivatives of Dihydroxypyrrolidine as Anti-Cancer Compounds |
| EP2409697A1 (en) | 2010-07-20 | 2012-01-25 | Université de Neuchâtel | Medicaments Based on Dinuclear Ruthenium, Osmium and Iron Complexes Comprising Triply Bridging Thiolato, Selenolato, Alkoxo and/or Amido Ligands |
| WO2013038395A1 (en) | 2011-09-16 | 2013-03-21 | Universidade De Lisboa | Transition metal complexes for pharmaceutical applications |
| WO2013136296A2 (en) | 2012-03-14 | 2013-09-19 | Universidade De Lisboa | Water-soluble organometallic ruthenium and iron compunds presenting heteroaromatic ligands |
| RU2682674C2 (ru) | 2013-03-15 | 2019-03-20 | Шерри Энн МАКФАРЛЭНД | Координационные комплексы на основе металлов в качестве фотодинамических соединений и их применение |
| US9751081B2 (en) | 2014-12-01 | 2017-09-05 | Clemson University | Self-regenerating antioxidant catalysts and methods of using the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19736152A1 (de) * | 1997-08-14 | 1999-02-18 | Martin Wehlan | Azido-Aziridinkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung |
| EP1224192B1 (en) * | 1999-10-27 | 2005-08-31 | The University Court, The University Of Edinburgh | Half-sandwich ruthenium (ii) compounds comprising nitrogen containing ligands for treatment of cancer |
| GB0016052D0 (en) * | 2000-06-30 | 2000-08-23 | Univ Edinburgh | Ruthenium (II) compounds |
| GB0215526D0 (en) * | 2002-07-05 | 2002-08-14 | Univ Edinburgh | Anticancer compounds |
-
2004
- 2004-08-20 GB GBGB0418643.3A patent/GB0418643D0/en not_active Ceased
-
2005
- 2005-08-19 EP EP05771813A patent/EP1786412A1/en not_active Withdrawn
- 2005-08-19 CA CA002578280A patent/CA2578280A1/en not_active Abandoned
- 2005-08-19 CN CNA2005800355417A patent/CN101043885A/zh active Pending
- 2005-08-19 AU AU2005273726A patent/AU2005273726A1/en not_active Abandoned
- 2005-08-19 BR BRPI0514430-2A patent/BRPI0514430A/pt not_active IP Right Cessation
- 2005-08-19 WO PCT/GB2005/003242 patent/WO2006018649A1/en active Application Filing
- 2005-08-19 MX MX2007002099A patent/MX2007002099A/es not_active Application Discontinuation
- 2005-08-19 JP JP2007526570A patent/JP2008510693A/ja active Pending
- 2005-08-19 KR KR1020077006364A patent/KR20070060091A/ko not_active Application Discontinuation
-
2007
- 2007-03-12 ZA ZA200702093A patent/ZA200702093B/xx unknown
- 2007-03-20 NO NO20071481A patent/NO20071481L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006018649A1 (en) | 2006-02-23 |
| CN101043885A (zh) | 2007-09-26 |
| AU2005273726A1 (en) | 2006-02-23 |
| JP2008510693A (ja) | 2008-04-10 |
| GB0418643D0 (en) | 2004-09-22 |
| MX2007002099A (es) | 2007-04-24 |
| EP1786412A1 (en) | 2007-05-23 |
| ZA200702093B (en) | 2008-08-27 |
| BRPI0514430A (pt) | 2008-05-06 |
| CA2578280A1 (en) | 2006-02-23 |
| KR20070060091A (ko) | 2007-06-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |