JP2008506665A5 - - Google Patents
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- Publication number
- JP2008506665A5 JP2008506665A5 JP2007520813A JP2007520813A JP2008506665A5 JP 2008506665 A5 JP2008506665 A5 JP 2008506665A5 JP 2007520813 A JP2007520813 A JP 2007520813A JP 2007520813 A JP2007520813 A JP 2007520813A JP 2008506665 A5 JP2008506665 A5 JP 2008506665A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- kit according
- app
- antibody
- kit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001413 amino acids Chemical class 0.000 claims 12
- 108010079054 Amyloid beta-Protein Precursor Proteins 0.000 claims 7
- 102000018430 Amyloid-beta precursor proteins Human genes 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 108010090849 Amyloid beta-Peptides Proteins 0.000 claims 2
- 102000013455 Amyloid beta-Peptides Human genes 0.000 claims 2
- 102000004878 Gelsolin Human genes 0.000 claims 2
- 108090001064 Gelsolin Proteins 0.000 claims 2
- 108010064539 amyloid beta-protein (1-42) Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 230000009919 sequestration Effects 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 claims 1
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 102000013918 Apolipoproteins E Human genes 0.000 claims 1
- 108010025628 Apolipoproteins E Proteins 0.000 claims 1
- 108091023037 Aptamer Proteins 0.000 claims 1
- 150000008574 D-amino acids Chemical class 0.000 claims 1
- 229930186217 Glycolipid Natural products 0.000 claims 1
- 238000002617 apheresis Methods 0.000 claims 1
- -1 aromatic amino acid Chemical class 0.000 claims 1
- 102000023732 binding proteins Human genes 0.000 claims 1
- 108091008324 binding proteins Proteins 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 238000002648 combination therapy Methods 0.000 claims 1
- 150000002270 gangliosides Chemical class 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002510 pyrogen Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ATA1185/2004 | 2004-07-13 | ||
| AT0118504A AT500483B1 (de) | 2004-07-13 | 2004-07-13 | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| PCT/EP2005/053224 WO2006005706A2 (de) | 2004-07-13 | 2005-07-06 | Kombinationstherapie zur vorbeugung oder behandlung der alzheimer´schen erkrankung sowie kit hierfür |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013010868A Division JP2013116903A (ja) | 2004-07-13 | 2013-01-24 | アルツハイマー病の予防または治療のための併用療法およびそのキット |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008506665A JP2008506665A (ja) | 2008-03-06 |
| JP2008506665A5 true JP2008506665A5 (enExample) | 2008-08-14 |
| JP5642333B2 JP5642333B2 (ja) | 2014-12-17 |
Family
ID=35115768
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007520813A Expired - Fee Related JP5642333B2 (ja) | 2004-07-13 | 2005-07-06 | アルツハイマー病の予防または治療のための併用療法およびそのキット |
| JP2013010868A Pending JP2013116903A (ja) | 2004-07-13 | 2013-01-24 | アルツハイマー病の予防または治療のための併用療法およびそのキット |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013010868A Pending JP2013116903A (ja) | 2004-07-13 | 2013-01-24 | アルツハイマー病の予防または治療のための併用療法およびそのキット |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7935348B2 (enExample) |
| EP (1) | EP1765388B8 (enExample) |
| JP (2) | JP5642333B2 (enExample) |
| KR (1) | KR101158600B1 (enExample) |
| CN (1) | CN101022825B (enExample) |
| AT (1) | AT500483B1 (enExample) |
| AU (1) | AU2005261687B8 (enExample) |
| CA (1) | CA2577332C (enExample) |
| DK (1) | DK1765388T3 (enExample) |
| ES (1) | ES2414872T3 (enExample) |
| PL (1) | PL1765388T3 (enExample) |
| PT (1) | PT1765388E (enExample) |
| TW (1) | TW200602072A (enExample) |
| WO (1) | WO2006005706A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004056318A2 (en) | 2002-12-19 | 2004-07-08 | New York University | Method for treating amyloid disease |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| AT500483B1 (de) * | 2004-07-13 | 2006-01-15 | Mattner Frank Dr | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| KR20080090408A (ko) | 2005-11-30 | 2008-10-08 | 아보트 러보러터리즈 | 항-Ａβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법 |
| SG10201706600VA (en) | 2005-11-30 | 2017-09-28 | Abbvie Inc | Monoclonal antibodies and uses thereof |
| US8455626B2 (en) * | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| WO2008080045A2 (en) * | 2006-12-22 | 2008-07-03 | Genentech, Inc. | Dr6 antibodies inhibiting the binding of dr6 to app, and uses thereof in treating neurological disorders |
| WO2008104386A2 (en) * | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
| EP2226081A4 (en) | 2007-10-25 | 2011-10-12 | Univ Kagoshima | PEPTIDE VACCINE WITH A MIMIC MOLECULE OF AMYLOID PEPTIDE |
| ES2332846B1 (es) | 2007-10-26 | 2010-07-08 | Grifols, S.A. | Utilizacion de albumina humana terapeutica para la preparacion de un medicamento para el tratamiento de pacientes afectados por desordenes cognitivos. |
| AT506820B1 (de) * | 2008-06-12 | 2011-07-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzine gegen alzheimer-krankheit |
| AT506819B1 (de) * | 2008-06-12 | 2011-06-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzin zur behandlung von alzheimer-krankheit |
| EP2320987A1 (en) * | 2008-07-29 | 2011-05-18 | Medtronic, Inc. | Apheresis of a target molecule from cerebrospinal fluid |
| HUE027027T2 (en) * | 2008-11-13 | 2016-08-29 | Modgene Llc | Reduction of amyloid beta load in non-brain tissue |
| CN104274875A (zh) | 2008-12-22 | 2015-01-14 | 学校法人藤田学园 | Aβ 除去材料、Aβ 除去器和Aβ 除去系统 |
| US20110033463A1 (en) * | 2009-08-06 | 2011-02-10 | Medtronic, Inc. | Apheresis, administration of agent, or combination thereof |
| EP2558494B1 (en) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta binding proteins |
| JP5843345B2 (ja) | 2010-07-08 | 2016-01-13 | 旭化成メディカル株式会社 | β−アミロイド除去システム |
| US9062101B2 (en) | 2010-08-14 | 2015-06-23 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| US20120321694A1 (en) * | 2010-10-27 | 2012-12-20 | Daniel Larocque | Compositions and uses |
| DK2579042T3 (da) | 2011-10-04 | 2014-07-21 | Affiris Ag | Fremgangsmåde til at påvise Aß-specifikke antistoffer i en biologisk prøve |
| MX352749B (es) | 2011-11-01 | 2017-12-06 | Modgene Llc | Composiciones y metodos para la reduccion de la carga amiloide-beta. |
| CN110133298A (zh) * | 2012-03-18 | 2019-08-16 | 株式会社资生堂 | 疾病样品分析装置、分析系统及分析方法 |
| DE102012108598A1 (de) * | 2012-09-14 | 2014-04-10 | Forschungszentrum Jülich GmbH | Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung |
| JP2015518474A (ja) * | 2012-04-05 | 2015-07-02 | フォルシュングスツェントルム ユーリッヒ ゲゼルシャフト ミット ベシュレンクテル ハフツングＦｏｒｓｃｈｕｎｇｓｚｅｎｔｒｕｍ Ｊｕｅｌｉｃｈ ＧｍｂＨ | 血液、血液生産物及び器官を処置する方法 |
| CN104380111B (zh) | 2012-04-05 | 2017-08-29 | 于利希研究中心有限公司 | 包含多价结合淀粉样β蛋白的D‑肽的聚合物及其应用 |
| KR101416954B1 (ko) * | 2012-09-12 | 2014-07-16 | 한양대학교 산학협력단 | 조혈세포 분화 유도 방법 |
| EP3116893B1 (en) * | 2014-03-11 | 2019-08-28 | Jacques Fantini | A chimeric peptide that interacts with cell membrane gangliosides |
| CN106466298A (zh) * | 2015-08-14 | 2017-03-01 | 上海交通大学医学院 | 一种单唾液酸四己糖神经节苷脂修饰的重组脂蛋白及其应用 |
| CN109414482A (zh) * | 2016-05-12 | 2019-03-01 | 俄亥俄州创新基金会 | 用于治疗神经退行性疾病的肽和方法 |
| EP3655001A4 (en) * | 2017-07-17 | 2021-04-28 | Spark Therapeutics, Inc. | Apheresis methods and uses |
| AU2018308088B2 (en) | 2017-07-25 | 2025-05-29 | Truebinding, Inc. | Treating cancer by blocking the interaction of TIM-3 and its ligand |
| US12281166B2 (en) | 2020-05-26 | 2025-04-22 | Truebinding, Inc. | Methods of treating inflammatory diseases by blocking Galectin-3 |
| CN115957324A (zh) * | 2021-10-12 | 2023-04-14 | 首都医科大学宣武医院 | 外周CLU作为靶点在降低脑Aβ中的应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5476715A (en) | 1989-10-03 | 1995-12-19 | Fresenius Ag | Particulate adsorbent for the removal of biomacromolecules such as LDL and endotoxins from whole blood in extracorporeal circuits |
| JP3161604B2 (ja) | 1994-05-13 | 2001-04-25 | プラズマセレクト ゲーエムベーハー テテロウ | 血液中の物質を結合してそれを除去するためのタンパク質を結合させた、無菌かつ発熱物質を含有しないカラム |
| EP0886085B1 (en) | 1997-06-18 | 2002-04-03 | Morse Tec Europe S.p.A. | Sprocket wheel with improved tooth profile for greater silentness |
| US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| US6551266B1 (en) | 1998-12-29 | 2003-04-22 | Occulogix Corporation | Rheological treatment methods and related apheresis systems |
| PE20020574A1 (es) * | 2000-12-06 | 2002-07-02 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido amiloideo beta |
| ES2279869T3 (es) | 2001-06-20 | 2007-09-01 | Ramot At Tel Aviv University Ltd. | Peptido antigenico comprendido por mulitples copias de un epitope de un polipeptido implicado en enfermedades de formacion de placas y los procedimientos de uso correspondientes. |
| US20050227941A1 (en) * | 2001-12-17 | 2005-10-13 | Karen Duff | Sequestration of ass in the periphery in the absence of immunomodulating agent as a therapeutic approach for the treatment or prevention of beta-amyloid related diseases |
| CA2487528A1 (en) | 2002-07-24 | 2004-02-12 | Innogenetics N.V. | Prevention, treatment and diagnosis of diseases associated with beta-amyloid formation and/or aggregation |
| WO2004056318A2 (en) * | 2002-12-19 | 2004-07-08 | New York University | Method for treating amyloid disease |
| AT413945B (de) * | 2003-01-14 | 2006-07-15 | Mattner Frank Dr | Impfstoff für die alzheimer-krankheit |
| PL378571A1 (pl) * | 2003-02-01 | 2006-05-02 | Neuralab Limited | Czynna immunizacja dla wytworzenia przeciwciał przeciw rozpuszczalnemu A-ß |
| AT413336B (de) * | 2003-09-12 | 2006-02-15 | Mattner Frank Dr | Apherese-vorrichtung |
| US20050158306A1 (en) * | 2004-01-16 | 2005-07-21 | Halikas James A. | Treatment for neuro-degenerative disease by a blood cleansing system using monoclonal antibodies |
| AT413946B (de) * | 2004-07-13 | 2006-07-15 | Mattner Frank Dr | Impfstoff gegen die alzheimer-krankheit |
| AT500483B1 (de) * | 2004-07-13 | 2006-01-15 | Mattner Frank Dr | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| AT500835B1 (de) * | 2004-09-13 | 2007-12-15 | Affiris Forschungs & Entwicklungs Gmbh | Cholinestertransport-protein-mimotop als atherosklerose-medikament |
-
2004
- 2004-07-13 AT AT0118504A patent/AT500483B1/de not_active IP Right Cessation
-
2005
- 2005-06-17 TW TW094120199A patent/TW200602072A/zh not_active IP Right Cessation
- 2005-07-06 CA CA2577332A patent/CA2577332C/en not_active Expired - Fee Related
- 2005-07-06 CN CN200580023830.5A patent/CN101022825B/zh not_active Expired - Fee Related
- 2005-07-06 JP JP2007520813A patent/JP5642333B2/ja not_active Expired - Fee Related
- 2005-07-06 KR KR1020077002208A patent/KR101158600B1/ko not_active Expired - Fee Related
- 2005-07-06 EP EP05767978.9A patent/EP1765388B8/de not_active Expired - Lifetime
- 2005-07-06 PL PL05767978T patent/PL1765388T3/pl unknown
- 2005-07-06 DK DK05767978.9T patent/DK1765388T3/da active
- 2005-07-06 WO PCT/EP2005/053224 patent/WO2006005706A2/de not_active Ceased
- 2005-07-06 ES ES05767978T patent/ES2414872T3/es not_active Expired - Lifetime
- 2005-07-06 US US11/571,970 patent/US7935348B2/en not_active Expired - Fee Related
- 2005-07-06 AU AU2005261687A patent/AU2005261687B8/en not_active Ceased
- 2005-07-06 PT PT57679789T patent/PT1765388E/pt unknown
-
2011
- 2011-03-11 US US13/045,967 patent/US20110201987A1/en not_active Abandoned
-
2013
- 2013-01-24 JP JP2013010868A patent/JP2013116903A/ja active Pending
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