AU2005261687B8 - Combination therapy for the prevention or treatment of Alzheimer's disease as well as kit therefor - Google Patents

Combination therapy for the prevention or treatment of Alzheimer's disease as well as kit therefor Download PDF

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Publication number
AU2005261687B8
AU2005261687B8 AU2005261687A AU2005261687A AU2005261687B8 AU 2005261687 B8 AU2005261687 B8 AU 2005261687B8 AU 2005261687 A AU2005261687 A AU 2005261687A AU 2005261687 A AU2005261687 A AU 2005261687A AU 2005261687 B8 AU2005261687 B8 AU 2005261687B8
Authority
AU
Australia
Prior art keywords
app
binding
kit according
amino acid
amyloid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005261687A
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English (en)
Other versions
AU2005261687B2 (en
AU2005261687A1 (en
Inventor
Frank Mattner
Walter Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affiris Forschungs und Entwicklungs GmbH
Original Assignee
Affiris Forschungs und Entwicklungs GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affiris Forschungs und Entwicklungs GmbH filed Critical Affiris Forschungs und Entwicklungs GmbH
Publication of AU2005261687A1 publication Critical patent/AU2005261687A1/en
Application granted granted Critical
Publication of AU2005261687B2 publication Critical patent/AU2005261687B2/en
Publication of AU2005261687B8 publication Critical patent/AU2005261687B8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6056Antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
AU2005261687A 2004-07-13 2005-07-06 Combination therapy for the prevention or treatment of Alzheimer's disease as well as kit therefor Ceased AU2005261687B8 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ATA1185/2004 2004-07-13
AT0118504A AT500483B1 (de) 2004-07-13 2004-07-13 Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung
PCT/EP2005/053224 WO2006005706A2 (de) 2004-07-13 2005-07-06 Kombinationstherapie zur vorbeugung oder behandlung der alzheimer´schen erkrankung sowie kit hierfür

Publications (3)

Publication Number Publication Date
AU2005261687A1 AU2005261687A1 (en) 2006-01-19
AU2005261687B2 AU2005261687B2 (en) 2011-02-17
AU2005261687B8 true AU2005261687B8 (en) 2011-07-21

Family

ID=35115768

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005261687A Ceased AU2005261687B8 (en) 2004-07-13 2005-07-06 Combination therapy for the prevention or treatment of Alzheimer's disease as well as kit therefor

Country Status (14)

Country Link
US (2) US7935348B2 (enExample)
EP (1) EP1765388B8 (enExample)
JP (2) JP5642333B2 (enExample)
KR (1) KR101158600B1 (enExample)
CN (1) CN101022825B (enExample)
AT (1) AT500483B1 (enExample)
AU (1) AU2005261687B8 (enExample)
CA (1) CA2577332C (enExample)
DK (1) DK1765388T3 (enExample)
ES (1) ES2414872T3 (enExample)
PL (1) PL1765388T3 (enExample)
PT (1) PT1765388E (enExample)
TW (1) TW200602072A (enExample)
WO (1) WO2006005706A2 (enExample)

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WO2004056318A2 (en) 2002-12-19 2004-07-08 New York University Method for treating amyloid disease
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
AT500483B1 (de) * 2004-07-13 2006-01-15 Mattner Frank Dr Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung
KR20080090408A (ko) 2005-11-30 2008-10-08 아보트 러보러터리즈 항-Aβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법
SG10201706600VA (en) 2005-11-30 2017-09-28 Abbvie Inc Monoclonal antibodies and uses thereof
US8455626B2 (en) * 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
WO2008080045A2 (en) * 2006-12-22 2008-07-03 Genentech, Inc. Dr6 antibodies inhibiting the binding of dr6 to app, and uses thereof in treating neurological disorders
WO2008104386A2 (en) * 2007-02-27 2008-09-04 Abbott Gmbh & Co. Kg Method for the treatment of amyloidoses
EP2226081A4 (en) 2007-10-25 2011-10-12 Univ Kagoshima PEPTIDE VACCINE WITH A MIMIC MOLECULE OF AMYLOID PEPTIDE
ES2332846B1 (es) 2007-10-26 2010-07-08 Grifols, S.A. Utilizacion de albumina humana terapeutica para la preparacion de un medicamento para el tratamiento de pacientes afectados por desordenes cognitivos.
AT506820B1 (de) * 2008-06-12 2011-07-15 Affiris Forschungs Und Entwicklungs Gmbh Vakzine gegen alzheimer-krankheit
AT506819B1 (de) * 2008-06-12 2011-06-15 Affiris Forschungs Und Entwicklungs Gmbh Vakzin zur behandlung von alzheimer-krankheit
EP2320987A1 (en) * 2008-07-29 2011-05-18 Medtronic, Inc. Apheresis of a target molecule from cerebrospinal fluid
HUE027027T2 (en) * 2008-11-13 2016-08-29 Modgene Llc Reduction of amyloid beta load in non-brain tissue
CN104274875A (zh) 2008-12-22 2015-01-14 学校法人藤田学园 Aβ 除去材料、Aβ 除去器和Aβ 除去系统
US20110033463A1 (en) * 2009-08-06 2011-02-10 Medtronic, Inc. Apheresis, administration of agent, or combination thereof
EP2558494B1 (en) 2010-04-15 2018-05-23 AbbVie Inc. Amyloid-beta binding proteins
JP5843345B2 (ja) 2010-07-08 2016-01-13 旭化成メディカル株式会社 β−アミロイド除去システム
US9062101B2 (en) 2010-08-14 2015-06-23 AbbVie Deutschland GmbH & Co. KG Amyloid-beta binding proteins
US20120321694A1 (en) * 2010-10-27 2012-12-20 Daniel Larocque Compositions and uses
DK2579042T3 (da) 2011-10-04 2014-07-21 Affiris Ag Fremgangsmåde til at påvise Aß-specifikke antistoffer i en biologisk prøve
MX352749B (es) 2011-11-01 2017-12-06 Modgene Llc Composiciones y metodos para la reduccion de la carga amiloide-beta.
CN110133298A (zh) * 2012-03-18 2019-08-16 株式会社资生堂 疾病样品分析装置、分析系统及分析方法
DE102012108598A1 (de) * 2012-09-14 2014-04-10 Forschungszentrum Jülich GmbH Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung
JP2015518474A (ja) * 2012-04-05 2015-07-02 フォルシュングスツェントルム ユーリッヒ ゲゼルシャフト ミット ベシュレンクテル ハフツングForschungszentrum Juelich GmbH 血液、血液生産物及び器官を処置する方法
CN104380111B (zh) 2012-04-05 2017-08-29 于利希研究中心有限公司 包含多价结合淀粉样β蛋白的D‑肽的聚合物及其应用
KR101416954B1 (ko) * 2012-09-12 2014-07-16 한양대학교 산학협력단 조혈세포 분화 유도 방법
EP3116893B1 (en) * 2014-03-11 2019-08-28 Jacques Fantini A chimeric peptide that interacts with cell membrane gangliosides
CN106466298A (zh) * 2015-08-14 2017-03-01 上海交通大学医学院 一种单唾液酸四己糖神经节苷脂修饰的重组脂蛋白及其应用
CN109414482A (zh) * 2016-05-12 2019-03-01 俄亥俄州创新基金会 用于治疗神经退行性疾病的肽和方法
EP3655001A4 (en) * 2017-07-17 2021-04-28 Spark Therapeutics, Inc. Apheresis methods and uses
AU2018308088B2 (en) 2017-07-25 2025-05-29 Truebinding, Inc. Treating cancer by blocking the interaction of TIM-3 and its ligand
US12281166B2 (en) 2020-05-26 2025-04-22 Truebinding, Inc. Methods of treating inflammatory diseases by blocking Galectin-3
CN115957324A (zh) * 2021-10-12 2023-04-14 首都医科大学宣武医院 外周CLU作为靶点在降低脑Aβ中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004056318A2 (en) * 2002-12-19 2004-07-08 New York University Method for treating amyloid disease

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JP3161604B2 (ja) 1994-05-13 2001-04-25 プラズマセレクト ゲーエムベーハー テテロウ 血液中の物質を結合してそれを除去するためのタンパク質を結合させた、無菌かつ発熱物質を含有しないカラム
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AT413945B (de) * 2003-01-14 2006-07-15 Mattner Frank Dr Impfstoff für die alzheimer-krankheit
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Also Published As

Publication number Publication date
KR101158600B1 (ko) 2012-07-09
US7935348B2 (en) 2011-05-03
DK1765388T3 (da) 2013-07-22
AT500483B1 (de) 2006-01-15
KR20070036158A (ko) 2007-04-02
CA2577332A1 (en) 2006-01-19
JP2008506665A (ja) 2008-03-06
TWI350173B (enExample) 2011-10-11
JP5642333B2 (ja) 2014-12-17
JP2013116903A (ja) 2013-06-13
TW200602072A (en) 2006-01-16
AU2005261687B2 (en) 2011-02-17
ES2414872T3 (es) 2013-07-23
EP1765388B1 (de) 2013-04-17
US20110201987A1 (en) 2011-08-18
CA2577332C (en) 2014-12-09
EP1765388B8 (de) 2013-05-29
HK1103354A1 (en) 2007-12-21
PL1765388T3 (pl) 2013-09-30
AT500483A4 (de) 2006-01-15
CN101022825A (zh) 2007-08-22
PT1765388E (pt) 2013-05-24
US20080051690A1 (en) 2008-02-28
CN101022825B (zh) 2015-02-04
AU2005261687A1 (en) 2006-01-19
WO2006005706A3 (de) 2006-07-20
WO2006005706A8 (de) 2006-11-16
WO2006005706A2 (de) 2006-01-19
EP1765388A2 (de) 2007-03-28
ES2414872T8 (es) 2014-11-06

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Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ COMBINATION THERAPY FOR THE PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE AS WELL AS KIT THEREFOR

TH Corrigenda

Free format text: IN VOL 25, NO 7, PAGE(S) 815 UNDER THE HEADING APPLICATIONS ACCEPTED - NAME INDEX UNDER THE NAME AFFIRIS FORSCHUNGS-UND ENTWICKLUNGS GMBH, APPLICATION NO.2005261687, UNDER INID (54) CORRECT THE TITLE TO READ COMBINATION THERAPY FOR THE PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE AS WELL AS KIT THEREFOR

MK14 Patent ceased section 143(a) (annual fees not paid) or expired