TW200602072A - Combination therapy for preventing or treating alzheimer's disease, and kit therefor - Google Patents
Combination therapy for preventing or treating alzheimer's disease, and kit thereforInfo
- Publication number
- TW200602072A TW200602072A TW094120199A TW94120199A TW200602072A TW 200602072 A TW200602072 A TW 200602072A TW 094120199 A TW094120199 A TW 094120199A TW 94120199 A TW94120199 A TW 94120199A TW 200602072 A TW200602072 A TW 200602072A
- Authority
- TW
- Taiwan
- Prior art keywords
- disease
- preventing
- treating alzheimer
- combination therapy
- kit therefor
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 3
- 238000002648 combination therapy Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 238000002617 apheresis Methods 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 230000009919 sequestration Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6056—Antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Marine Sciences & Fisheries (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0118504A AT500483B1 (de) | 2004-07-13 | 2004-07-13 | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200602072A true TW200602072A (en) | 2006-01-16 |
| TWI350173B TWI350173B (enExample) | 2011-10-11 |
Family
ID=35115768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW094120199A TW200602072A (en) | 2004-07-13 | 2005-06-17 | Combination therapy for preventing or treating alzheimer's disease, and kit therefor |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7935348B2 (enExample) |
| EP (1) | EP1765388B8 (enExample) |
| JP (2) | JP5642333B2 (enExample) |
| KR (1) | KR101158600B1 (enExample) |
| CN (1) | CN101022825B (enExample) |
| AT (1) | AT500483B1 (enExample) |
| AU (1) | AU2005261687B8 (enExample) |
| CA (1) | CA2577332C (enExample) |
| DK (1) | DK1765388T3 (enExample) |
| ES (1) | ES2414872T3 (enExample) |
| PL (1) | PL1765388T3 (enExample) |
| PT (1) | PT1765388E (enExample) |
| TW (1) | TW200602072A (enExample) |
| WO (1) | WO2006005706A2 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003303198A1 (en) | 2002-12-19 | 2004-07-14 | New York University | Method for treating amyloid disease |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| AT500483B1 (de) * | 2004-07-13 | 2006-01-15 | Mattner Frank Dr | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| CN101506236B (zh) | 2005-11-30 | 2012-12-12 | 雅培制药有限公司 | 抗淀粉样β蛋白的单克隆抗体及其用途 |
| RU2442793C2 (ru) * | 2005-11-30 | 2012-02-20 | Эбботт Лэборетриз | АНТИТЕЛА ПРОТИВ ГЛОБУЛОМЕРА Аβ, ИХ АНТИГЕНСВЯЗЫВАЮЩИЕ ЧАСТИ, СООТВЕТСТВУЮЩИЕ ГИБРИДОМЫ, НУКЛЕИНОВЫЕ КИСЛОТЫ, ВЕКТОРЫ, КЛЕТКИ-ХОЗЯЕВА, СПОСОБЫ ПОЛУЧЕНИЯ УКАЗАННЫХ АНТИТЕЛ, КОМПОЗИЦИИ, СОДЕРЖАЩИЕ УКАЗАННЫЕ АНТИТЕЛА, ПРИМЕНЕНИЯ УКАЗАННЫХ АНТИТЕЛ И СПОСОБЫ ИСПОЛЬЗОВАНИЯ УКАЗАННЫХ АНТИТЕЛ |
| US8455626B2 (en) * | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| RU2009128039A (ru) * | 2006-12-22 | 2011-01-27 | Дженентек, Инк. (Us) | Антагонисты dr6 и способы их применения в лечении неврологических нарушений |
| EP2124952A2 (en) * | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| US8586706B2 (en) | 2007-10-25 | 2013-11-19 | Kagoshima University | Peptide vaccine using mimic molecules of amyloid β peptide |
| ES2332846B1 (es) | 2007-10-26 | 2010-07-08 | Grifols, S.A. | Utilizacion de albumina humana terapeutica para la preparacion de un medicamento para el tratamiento de pacientes afectados por desordenes cognitivos. |
| AT506820B1 (de) * | 2008-06-12 | 2011-07-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzine gegen alzheimer-krankheit |
| AT506819B1 (de) * | 2008-06-12 | 2011-06-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzin zur behandlung von alzheimer-krankheit |
| WO2010014702A1 (en) * | 2008-07-29 | 2010-02-04 | Medtronic, Inc. | Apheresis of a target molecule from cerebrospinal fluid |
| AU2009313851A1 (en) * | 2008-11-13 | 2010-05-20 | Modgene, Llc | Modification of amyloid-beta load in non-brain tissue |
| KR101538361B1 (ko) | 2008-12-22 | 2015-07-22 | 후지타 헬쓰 유니버시티 | Aβ 제거재, Aβ 제거기 및 Aβ 제거 시스템 |
| US20110033463A1 (en) * | 2009-08-06 | 2011-02-10 | Medtronic, Inc. | Apheresis, administration of agent, or combination thereof |
| US8987419B2 (en) | 2010-04-15 | 2015-03-24 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| US10112000B2 (en) | 2010-07-08 | 2018-10-30 | Asahi Kasei Medical Co., Ltd. | Method for reducing amyloid beta concentration in blood |
| CN103298833B (zh) | 2010-08-14 | 2015-12-16 | Abbvie公司 | β淀粉样蛋白结合蛋白 |
| US20120321694A1 (en) * | 2010-10-27 | 2012-12-20 | Daniel Larocque | Compositions and uses |
| RS53496B1 (sr) | 2011-10-04 | 2015-02-27 | Affiris Ag | POSTUPAK ZA DETEKCIJU Aβ-SPECIFIČNIH ANTITELA U BIOLOŠKOM UZORKU |
| WO2013067157A1 (en) | 2011-11-01 | 2013-05-10 | Modgene, Llc | Compositions and methods for reduction of amyloid-beta load |
| CN110133298A (zh) * | 2012-03-18 | 2019-08-16 | 株式会社资生堂 | 疾病样品分析装置、分析系统及分析方法 |
| DE102012108598A1 (de) * | 2012-09-14 | 2014-04-10 | Forschungszentrum Jülich GmbH | Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung |
| PL3260865T3 (pl) | 2012-04-05 | 2023-04-11 | Priavoid Gmbh | Sposób obróbki krwi, produktów krwiopochodnych i narządów |
| DK2834644T3 (da) | 2012-04-05 | 2019-11-04 | Forschungszentrum Juelich Gmbh | Polymerer, indeholdende multivalente amyloid-beta-bindende d-peptider og deres anvendelse |
| KR101416954B1 (ko) * | 2012-09-12 | 2014-07-16 | 한양대학교 산학협력단 | 조혈세포 분화 유도 방법 |
| EP3116893B1 (en) * | 2014-03-11 | 2019-08-28 | Jacques Fantini | A chimeric peptide that interacts with cell membrane gangliosides |
| CN106466298A (zh) * | 2015-08-14 | 2017-03-01 | 上海交通大学医学院 | 一种单唾液酸四己糖神经节苷脂修饰的重组脂蛋白及其应用 |
| EP3454885A4 (en) * | 2016-05-12 | 2019-12-25 | Ohio State Innovation Foundation | PEPTIDES AND METHOD FOR TREATING NEURODEGENERATIVE DISORDERS |
| CA3069880A1 (en) * | 2017-07-17 | 2019-01-24 | Spark Therapeutics, Inc. | Apheresis methods and uses |
| US12227567B2 (en) | 2017-07-25 | 2025-02-18 | Truebinding, Inc. | Treating cancer by blocking the interaction of TIM-3 and its ligand |
| CN116063520A (zh) | 2019-01-30 | 2023-05-05 | 真和制药有限公司 | 抗gal3抗体及其用途 |
| CN116157151A (zh) | 2020-05-26 | 2023-05-23 | 真和制药有限公司 | 通过阻断半乳凝素-3治疗炎性疾病的方法 |
| CN115957324A (zh) * | 2021-10-12 | 2023-04-14 | 首都医科大学宣武医院 | 外周CLU作为靶点在降低脑Aβ中的应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5476715A (en) | 1989-10-03 | 1995-12-19 | Fresenius Ag | Particulate adsorbent for the removal of biomacromolecules such as LDL and endotoxins from whole blood in extracorporeal circuits |
| ATE294959T1 (de) | 1994-05-13 | 2005-05-15 | Miltenyi Biotec Gmbh | An protein gebundene sterile und pyrogenfreie säulen zum binden und entfernen von substanzen aus blut |
| ES2175325T3 (es) | 1997-06-18 | 2002-11-16 | Morse Tec Europe Srl | Rueda dentada con perfil de dientes mejorado para funcionamiento mas silencioso. |
| US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| WO2000038760A2 (en) * | 1998-12-29 | 2000-07-06 | Occulogix Corporation | Rheological treatment methods and related apheresis systems |
| PE20020574A1 (es) * | 2000-12-06 | 2002-07-02 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido amiloideo beta |
| ES2279869T3 (es) * | 2001-06-20 | 2007-09-01 | Ramot At Tel Aviv University Ltd. | Peptido antigenico comprendido por mulitples copias de un epitope de un polipeptido implicado en enfermedades de formacion de placas y los procedimientos de uso correspondientes. |
| US20050227941A1 (en) * | 2001-12-17 | 2005-10-13 | Karen Duff | Sequestration of ass in the periphery in the absence of immunomodulating agent as a therapeutic approach for the treatment or prevention of beta-amyloid related diseases |
| CA2487528A1 (en) * | 2002-07-24 | 2004-02-12 | Innogenetics N.V. | Prevention, treatment and diagnosis of diseases associated with beta-amyloid formation and/or aggregation |
| AU2003303198A1 (en) * | 2002-12-19 | 2004-07-14 | New York University | Method for treating amyloid disease |
| AT413945B (de) * | 2003-01-14 | 2006-07-15 | Mattner Frank Dr | Impfstoff für die alzheimer-krankheit |
| UA87453C2 (ru) * | 2003-02-01 | 2009-07-27 | Вайет | Применения фрагмента ав для лечения болезни альцгеймера |
| AT413336B (de) | 2003-09-12 | 2006-02-15 | Mattner Frank Dr | Apherese-vorrichtung |
| US20050158306A1 (en) * | 2004-01-16 | 2005-07-21 | Halikas James A. | Treatment for neuro-degenerative disease by a blood cleansing system using monoclonal antibodies |
| AT500483B1 (de) * | 2004-07-13 | 2006-01-15 | Mattner Frank Dr | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| AT413946B (de) * | 2004-07-13 | 2006-07-15 | Mattner Frank Dr | Impfstoff gegen die alzheimer-krankheit |
| AT500835B1 (de) * | 2004-09-13 | 2007-12-15 | Affiris Forschungs & Entwicklungs Gmbh | Cholinestertransport-protein-mimotop als atherosklerose-medikament |
-
2004
- 2004-07-13 AT AT0118504A patent/AT500483B1/de not_active IP Right Cessation
-
2005
- 2005-06-17 TW TW094120199A patent/TW200602072A/zh not_active IP Right Cessation
- 2005-07-06 AU AU2005261687A patent/AU2005261687B8/en not_active Ceased
- 2005-07-06 WO PCT/EP2005/053224 patent/WO2006005706A2/de not_active Ceased
- 2005-07-06 CN CN200580023830.5A patent/CN101022825B/zh not_active Expired - Fee Related
- 2005-07-06 DK DK05767978.9T patent/DK1765388T3/da active
- 2005-07-06 US US11/571,970 patent/US7935348B2/en not_active Expired - Fee Related
- 2005-07-06 EP EP05767978.9A patent/EP1765388B8/de not_active Expired - Lifetime
- 2005-07-06 KR KR1020077002208A patent/KR101158600B1/ko not_active Expired - Fee Related
- 2005-07-06 PT PT57679789T patent/PT1765388E/pt unknown
- 2005-07-06 ES ES05767978T patent/ES2414872T3/es not_active Expired - Lifetime
- 2005-07-06 JP JP2007520813A patent/JP5642333B2/ja not_active Expired - Fee Related
- 2005-07-06 CA CA2577332A patent/CA2577332C/en not_active Expired - Fee Related
- 2005-07-06 PL PL05767978T patent/PL1765388T3/pl unknown
-
2011
- 2011-03-11 US US13/045,967 patent/US20110201987A1/en not_active Abandoned
-
2013
- 2013-01-24 JP JP2013010868A patent/JP2013116903A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008506665A (ja) | 2008-03-06 |
| PL1765388T3 (pl) | 2013-09-30 |
| AU2005261687B8 (en) | 2011-07-21 |
| AT500483B1 (de) | 2006-01-15 |
| DK1765388T3 (da) | 2013-07-22 |
| KR20070036158A (ko) | 2007-04-02 |
| CN101022825A (zh) | 2007-08-22 |
| CA2577332A1 (en) | 2006-01-19 |
| ES2414872T8 (es) | 2014-11-06 |
| EP1765388B8 (de) | 2013-05-29 |
| AU2005261687A1 (en) | 2006-01-19 |
| TWI350173B (enExample) | 2011-10-11 |
| AU2005261687B2 (en) | 2011-02-17 |
| WO2006005706A2 (de) | 2006-01-19 |
| CN101022825B (zh) | 2015-02-04 |
| US20080051690A1 (en) | 2008-02-28 |
| WO2006005706A8 (de) | 2006-11-16 |
| AT500483A4 (de) | 2006-01-15 |
| CA2577332C (en) | 2014-12-09 |
| HK1103354A1 (en) | 2007-12-21 |
| WO2006005706A3 (de) | 2006-07-20 |
| US7935348B2 (en) | 2011-05-03 |
| EP1765388B1 (de) | 2013-04-17 |
| PT1765388E (pt) | 2013-05-24 |
| JP2013116903A (ja) | 2013-06-13 |
| KR101158600B1 (ko) | 2012-07-09 |
| US20110201987A1 (en) | 2011-08-18 |
| ES2414872T3 (es) | 2013-07-23 |
| JP5642333B2 (ja) | 2014-12-17 |
| EP1765388A2 (de) | 2007-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |