JP2018510213A5 - - Google Patents
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- Publication number
- JP2018510213A5 JP2018510213A5 JP2017564947A JP2017564947A JP2018510213A5 JP 2018510213 A5 JP2018510213 A5 JP 2018510213A5 JP 2017564947 A JP2017564947 A JP 2017564947A JP 2017564947 A JP2017564947 A JP 2017564947A JP 2018510213 A5 JP2018510213 A5 JP 2018510213A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- von willebrand
- treatment
- life
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 17
- 108010047303 von Willebrand Factor Proteins 0.000 claims 7
- 102100036537 von Willebrand factor Human genes 0.000 claims 7
- 229960001134 von willebrand factor Drugs 0.000 claims 7
- 108010054218 Factor VIII Proteins 0.000 claims 5
- 102000001690 Factor VIII Human genes 0.000 claims 5
- 229960000301 factor viii Drugs 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 102100032532 C-type lectin domain family 10 member A Human genes 0.000 claims 4
- 101000942296 Homo sapiens C-type lectin domain family 10 member A Proteins 0.000 claims 4
- 208000015294 blood coagulation disease Diseases 0.000 claims 2
- 102100026735 Coagulation factor VIII Human genes 0.000 claims 1
- 201000003542 Factor VIII deficiency Diseases 0.000 claims 1
- 208000009292 Hemophilia A Diseases 0.000 claims 1
- 101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 claims 1
- 208000027276 Von Willebrand disease Diseases 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000023555 blood coagulation Effects 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 208000012137 von Willebrand disease (hereditary or acquired) Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15158088 | 2015-03-06 | ||
| EP15158088.3 | 2015-03-06 | ||
| PCT/EP2016/054650 WO2016142289A1 (en) | 2015-03-06 | 2016-03-04 | Compounds for improving the half-life of von willebrand factor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018510213A JP2018510213A (ja) | 2018-04-12 |
| JP2018510213A5 true JP2018510213A5 (enExample) | 2019-04-04 |
| JP6704420B2 JP6704420B2 (ja) | 2020-06-03 |
Family
ID=52629453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017564947A Expired - Fee Related JP6704420B2 (ja) | 2015-03-06 | 2016-03-04 | フォンヴィレブランド因子の半減期を改善するための化合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20180043012A1 (enExample) |
| EP (1) | EP3265489B1 (enExample) |
| JP (1) | JP6704420B2 (enExample) |
| KR (1) | KR20170125942A (enExample) |
| CN (1) | CN107428831A (enExample) |
| AU (1) | AU2016231328B2 (enExample) |
| BR (1) | BR112017017852A2 (enExample) |
| CA (1) | CA2978134A1 (enExample) |
| DK (1) | DK3265489T3 (enExample) |
| ES (1) | ES2755449T3 (enExample) |
| SG (1) | SG11201706657PA (enExample) |
| WO (1) | WO2016142289A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230074641A (ko) * | 2020-09-23 | 2023-05-30 | 아블레비아 바이오테크 게엠베하 | 자가항체-매개 병태의 예방 또는 치료를 위한 화합물 |
| IL303089A (en) * | 2020-11-24 | 2023-07-01 | Band Therapeutics Llc | Compositions and methods for treatment of bleeding disorders |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| DE69735421T2 (de) * | 1996-04-24 | 2006-10-19 | The Regents Of The University Of Michigan, Ann Arbor | Gegen inaktivierung resistenter faktor viii |
| CA2465004A1 (en) * | 2003-05-19 | 2004-11-19 | National Institute For Biological Standards And Control | Composition |
| JP2005132796A (ja) * | 2003-10-31 | 2005-05-26 | Tatsuro Irimura | 肉芽組織形成性疾患の治療のための医薬組成物および方法 |
| EP1593388A1 (en) * | 2004-05-05 | 2005-11-09 | ZLB Behring GmbH | Therapeutic plasma protein-concentrates containing von willebrand factor as high molecular weight multimers |
| EP2662083A1 (en) * | 2012-05-08 | 2013-11-13 | CSL Behring GmbH | Sugar compositions for treating hemophilia a and/or von willebrand disease |
| EP2669679A1 (en) * | 2012-05-28 | 2013-12-04 | Universitätsklinikum Hamburg-Eppendorf | Method for the detection of glycans using polypeptides comprising the CD301 carbohydrate recognition domain |
| US10138291B2 (en) * | 2012-07-11 | 2018-11-27 | Bioverativ Therapeutics Inc. | Factor VIII complex with XTEN and von Willebrand Factor protein, and uses thereof |
| WO2014210558A1 (en) * | 2013-06-28 | 2014-12-31 | Biogen Idec Ma Inc. | Thrombin cleavable linker with xten and its uses thereof |
-
2016
- 2016-03-04 AU AU2016231328A patent/AU2016231328B2/en not_active Ceased
- 2016-03-04 US US15/555,828 patent/US20180043012A1/en not_active Abandoned
- 2016-03-04 JP JP2017564947A patent/JP6704420B2/ja not_active Expired - Fee Related
- 2016-03-04 ES ES16708978T patent/ES2755449T3/es active Active
- 2016-03-04 CN CN201680014068.2A patent/CN107428831A/zh active Pending
- 2016-03-04 BR BR112017017852-4A patent/BR112017017852A2/pt not_active Application Discontinuation
- 2016-03-04 EP EP16708978.8A patent/EP3265489B1/en active Active
- 2016-03-04 WO PCT/EP2016/054650 patent/WO2016142289A1/en not_active Ceased
- 2016-03-04 SG SG11201706657PA patent/SG11201706657PA/en unknown
- 2016-03-04 DK DK16708978.8T patent/DK3265489T3/da active
- 2016-03-04 KR KR1020177028209A patent/KR20170125942A/ko not_active Withdrawn
- 2016-03-04 CA CA2978134A patent/CA2978134A1/en not_active Abandoned