JP2016527286A5 - - Google Patents
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- JP2016527286A5 JP2016527286A5 JP2016532266A JP2016532266A JP2016527286A5 JP 2016527286 A5 JP2016527286 A5 JP 2016527286A5 JP 2016532266 A JP2016532266 A JP 2016532266A JP 2016532266 A JP2016532266 A JP 2016532266A JP 2016527286 A5 JP2016527286 A5 JP 2016527286A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- antibody
- amino acid
- interleukin
- combined
- Prior art date
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019123809A JP7565678B2 (ja) | 2013-08-08 | 2019-07-02 | 組合せ医薬組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13003964.7 | 2013-08-08 | ||
| EP13003964 | 2013-08-08 | ||
| PCT/EP2014/002182 WO2015018529A1 (en) | 2013-08-08 | 2014-08-08 | Combined pharmaceutical composition |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019123809A Division JP7565678B2 (ja) | 2013-08-08 | 2019-07-02 | 組合せ医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016527286A JP2016527286A (ja) | 2016-09-08 |
| JP2016527286A5 true JP2016527286A5 (enExample) | 2017-08-24 |
| JP6794255B2 JP6794255B2 (ja) | 2020-12-02 |
Family
ID=48951300
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016532266A Active JP6794255B2 (ja) | 2013-08-08 | 2014-08-08 | 組合せ医薬組成物 |
| JP2019123809A Active JP7565678B2 (ja) | 2013-08-08 | 2019-07-02 | 組合せ医薬組成物 |
| JP2022063995A Pending JP2022091985A (ja) | 2013-08-08 | 2022-04-07 | 組合せ医薬組成物 |
| JP2024092095A Withdrawn JP2024116254A (ja) | 2013-08-08 | 2024-06-06 | 組合せ医薬組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019123809A Active JP7565678B2 (ja) | 2013-08-08 | 2019-07-02 | 組合せ医薬組成物 |
| JP2022063995A Pending JP2022091985A (ja) | 2013-08-08 | 2022-04-07 | 組合せ医薬組成物 |
| JP2024092095A Withdrawn JP2024116254A (ja) | 2013-08-08 | 2024-06-06 | 組合せ医薬組成物 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US20160184399A1 (enExample) |
| EP (2) | EP3030262B1 (enExample) |
| JP (4) | JP6794255B2 (enExample) |
| KR (3) | KR102457731B1 (enExample) |
| CN (1) | CN105579062A (enExample) |
| CA (1) | CA2920539C (enExample) |
| CY (1) | CY1122465T1 (enExample) |
| DK (1) | DK3030262T3 (enExample) |
| ES (1) | ES2760249T3 (enExample) |
| HR (1) | HRP20192174T1 (enExample) |
| HU (1) | HUE046964T2 (enExample) |
| LT (1) | LT3030262T (enExample) |
| PL (1) | PL3030262T3 (enExample) |
| PT (1) | PT3030262T (enExample) |
| RS (1) | RS59756B1 (enExample) |
| SI (1) | SI3030262T1 (enExample) |
| SM (1) | SMT201900684T1 (enExample) |
| WO (1) | WO2015018529A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101365479B (zh) | 2005-12-02 | 2013-06-26 | 纽约大学西奈山医学院 | 呈现非天然表面蛋白的嵌合病毒及其应用 |
| WO2014158811A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Newcastle disease viruses and uses thereof |
| HUE046964T2 (hu) * | 2013-08-08 | 2020-04-28 | Cytune Pharma | Kombinált gyógyászati készítmény |
| CN105263521B (zh) * | 2014-01-15 | 2021-06-29 | 卡德门企业有限公司 | 免疫调节剂 |
| EP3441084A1 (en) | 2014-02-27 | 2019-02-13 | Viralytics Limited | Oncolytic virus and immuno-stimulatory agent for combined use in the treatment of cancer |
| EP2915569A1 (en) | 2014-03-03 | 2015-09-09 | Cytune Pharma | IL-15/IL-15Ralpha based conjugates purification method |
| US11173179B2 (en) | 2015-06-25 | 2021-11-16 | Icell Gene Therapeutics Llc | Chimeric antigen receptor (CAR) targeting multiple antigens, compositions and methods of use thereof |
| CA2990177A1 (en) | 2015-06-25 | 2016-12-29 | Icell Gene Therapeutics Llc | Chimeric antigen receptors (cars), compositions and methods thereof |
| JP6800219B2 (ja) * | 2015-09-16 | 2020-12-16 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 特異的なインターロイキン−１５（ｉｌ−１５）アンタゴニストポリペプチド並びに炎症疾患及び自己免疫疾患の処置のためのその使用 |
| WO2017123643A1 (en) * | 2016-01-11 | 2017-07-20 | Flagship Pioneering, Inc. | Methods and compositions for modulating thymic function |
| WO2017180587A2 (en) | 2016-04-11 | 2017-10-19 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| EP3458092A1 (en) | 2016-05-18 | 2019-03-27 | Modernatx, Inc. | Mrna combination therapy for the treatment of cancer |
| CN109715196A (zh) | 2016-06-13 | 2019-05-03 | 转矩医疗股份有限公司 | 用于促进免疫细胞功能的组合物和方法 |
| US20200283534A1 (en) * | 2016-06-24 | 2020-09-10 | iCell Gene Therapeuticics LLC | CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOF |
| WO2018026872A1 (en) * | 2016-08-01 | 2018-02-08 | Virogin Biotech Canada Ltd | Oncolytic herpes simplex virus vectors expressing immune system-stimulatory molecules |
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| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| JOP20190256A1 (ar) | 2017-05-12 | 2019-10-28 | Icahn School Med Mount Sinai | فيروسات داء نيوكاسل واستخداماتها |
| CN111247242B (zh) | 2017-06-21 | 2024-07-19 | 美商生物细胞基因治疗有限公司 | 嵌合抗原受体(CARs)、组合物及其使用方法 |
| EP3645122A1 (en) | 2017-06-30 | 2020-05-06 | Xencor, Inc. | Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and antigen binding domains |
| CA3074826A1 (en) | 2017-09-05 | 2019-03-14 | Torque Therapeutics, Inc. | Therapeutic protein compositions and methods of making and using the same |
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| EP3759129A1 (en) | 2018-02-28 | 2021-01-06 | Pfizer Inc | Il-15 variants and uses thereof |
| CN112105645A (zh) | 2018-04-18 | 2020-12-18 | Xencor股份有限公司 | Il-15/il-15ra异二聚体fc融合蛋白及其用途 |
| AU2019256529A1 (en) | 2018-04-18 | 2020-11-26 | Xencor, Inc. | TIM-3 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and TIM-3 antigen binding domains |
| WO2019204665A1 (en) | 2018-04-18 | 2019-10-24 | Xencor, Inc. | Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof |
| KR20210003813A (ko) | 2018-04-18 | 2021-01-12 | 젠코어 인코포레이티드 | IL-15/IL-15Rα Fc-융합 단백질 및 LAG-3 항원 결합 도메인을 함유하는 LAG-3 표적화 이종이량체 융합 단백질 |
| EP3837277A4 (en) | 2018-08-17 | 2022-05-11 | Icahn School of Medicine at Mount Sinai | RECOMBINANT NEWCASTLE DISEASE VIRUSES AND THEIR USES IN THE PREVENTION OF RSV DISEASE OR HUMAN METAPNEUMOVIRUS INFECTION |
| MX2021004059A (es) | 2018-10-12 | 2021-09-23 | Xencor Inc | Proteínas de fusión de il-15/il-15ralfa-fc dirigidas a pd-1 y usos de las mismas en terapias combinadas. |
| WO2020132646A1 (en) | 2018-12-20 | 2020-06-25 | Xencor, Inc. | Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains |
| MX2021014189A (es) * | 2019-05-20 | 2022-01-06 | Cytune Pharma | Regimenes de dosificacion de agonistas de la il-2/il-15r?y para el tratamiento del cancer o enfermedades infecciosas. |
| TW202128757A (zh) | 2019-10-11 | 2021-08-01 | 美商建南德克公司 | 具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白 |
| US20230034677A1 (en) * | 2019-11-21 | 2023-02-02 | INSERM (Institut National de la Santé et la Recherche (Médicale) | Novel immunotherapies targeting pd-1 with anti-pd-1/il-15 immunocytokines |
| CA3195276A1 (en) * | 2020-10-26 | 2022-05-05 | Stefano FERRARA | Il-2/il-15rb?? agonist for treating non-melanoma skin cancer |
| WO2022200525A1 (en) | 2021-03-26 | 2022-09-29 | Innate Pharma | Multispecific proteins comprising an nkp46-binding site, a cancer antgienge binding site fused to a cytokine for nk cell engaging |
| WO2022258678A1 (en) | 2021-06-09 | 2022-12-15 | Innate Pharma | Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a |
| WO2022258662A1 (en) | 2021-06-09 | 2022-12-15 | Innate Pharma | Multispecific proteins binding to nkp46, a cytokine receptor, a tumour antigen and cd16a |
| WO2022258691A1 (en) | 2021-06-09 | 2022-12-15 | Innate Pharma | Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a |
| KR20240051112A (ko) | 2021-07-01 | 2024-04-19 | 인답타 세라뷰틱스 인코포레이티드 | 조작된 자연 살해(nk) 세포 및 관련 방법 |
| US20230151095A1 (en) | 2021-11-12 | 2023-05-18 | Xencor, Inc. | Bispecific antibodies that bind to b7h3 and nkg2d |
| KR20250060188A (ko) | 2022-06-30 | 2025-05-07 | 인답타 세라뷰틱스 인코포레이티드 | 조작된 자연 살해(nk) 세포 및 항체 요법의 조합 및 관련 방법 |
| WO2024102636A1 (en) | 2022-11-07 | 2024-05-16 | Xencor, Inc. | Bispecific antibodies that bind to b7h3 and mica/b |
| WO2024186143A1 (ko) * | 2023-03-07 | 2024-09-12 | 한미약품 주식회사 | 암의 예방 또는 치료를 위한 인터루킨 2 아날로그 또는 이의 결합체 및 면역관문 억제제의 병용 요법 |
| WO2024186142A1 (ko) * | 2023-03-07 | 2024-09-12 | 한미약품 주식회사 | 인터루킨 2 아날로그 또는 이의 결합체를 포함하는 암의 예방 또는 치료용 약학적 조성물 |
| US20250243279A1 (en) | 2023-10-17 | 2025-07-31 | Xencor, Inc. | Bispecific antibodies that bind to nkp46 and mica/b |
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-
2014
- 2014-08-08 HU HUE14761281A patent/HUE046964T2/hu unknown
- 2014-08-08 KR KR1020167005437A patent/KR102457731B1/ko active Active
- 2014-08-08 JP JP2016532266A patent/JP6794255B2/ja active Active
- 2014-08-08 KR KR1020247021359A patent/KR102861895B1/ko active Active
- 2014-08-08 ES ES14761281T patent/ES2760249T3/es active Active
- 2014-08-08 CA CA2920539A patent/CA2920539C/en active Active
- 2014-08-08 DK DK14761281T patent/DK3030262T3/da active
- 2014-08-08 CN CN201480052637.3A patent/CN105579062A/zh active Pending
- 2014-08-08 EP EP14761281.6A patent/EP3030262B1/en active Active
- 2014-08-08 PT PT147612816T patent/PT3030262T/pt unknown
- 2014-08-08 US US14/910,491 patent/US20160184399A1/en not_active Abandoned
- 2014-08-08 PL PL14761281T patent/PL3030262T3/pl unknown
- 2014-08-08 LT LTEP14761281.6T patent/LT3030262T/lt unknown
- 2014-08-08 EP EP19201668.1A patent/EP3659622A1/en active Pending
- 2014-08-08 HR HRP20192174TT patent/HRP20192174T1/hr unknown
- 2014-08-08 RS RS20191542A patent/RS59756B1/sr unknown
- 2014-08-08 SI SI201431420T patent/SI3030262T1/sl unknown
- 2014-08-08 KR KR1020227036248A patent/KR20220148304A/ko not_active Ceased
- 2014-08-08 SM SM20190684T patent/SMT201900684T1/it unknown
- 2014-08-08 WO PCT/EP2014/002182 patent/WO2015018529A1/en not_active Ceased
-
2019
- 2019-07-02 JP JP2019123809A patent/JP7565678B2/ja active Active
- 2019-11-26 CY CY20191101235T patent/CY1122465T1/el unknown
-
2022
- 2022-02-22 US US17/677,589 patent/US20220168395A1/en active Pending
- 2022-03-15 US US17/695,688 patent/US20220202904A1/en active Pending
- 2022-04-07 JP JP2022063995A patent/JP2022091985A/ja active Pending
-
2024
- 2024-06-06 JP JP2024092095A patent/JP2024116254A/ja not_active Withdrawn
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