JP2008503501A5 - - Google Patents

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Publication number
JP2008503501A5
JP2008503501A5 JP2007516842A JP2007516842A JP2008503501A5 JP 2008503501 A5 JP2008503501 A5 JP 2008503501A5 JP 2007516842 A JP2007516842 A JP 2007516842A JP 2007516842 A JP2007516842 A JP 2007516842A JP 2008503501 A5 JP2008503501 A5 JP 2008503501A5
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JP
Japan
Prior art keywords
imidazol
benzyl
phenyl
dimethylpropyl
propyl
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JP2007516842A
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English (en)
Japanese (ja)
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JP4836280B2 (ja
JP2008503501A (ja
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Priority claimed from PCT/US2005/022062 external-priority patent/WO2006002236A1/en
Publication of JP2008503501A publication Critical patent/JP2008503501A/ja
Publication of JP2008503501A5 publication Critical patent/JP2008503501A5/ja
Application granted granted Critical
Publication of JP4836280B2 publication Critical patent/JP4836280B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2007516842A 2004-06-18 2005-06-20 癌を治療するためのキネシンスピンドルタンパク質（ｋｓｐ）阻害剤としてのｎ−（１−（１−ベンジル−４−フェニル−１ｈ−イミダゾール−２−イル）−２，２−ジメチルプロピル）ベンズアミド誘導体および関連化合物 Expired - Fee Related JP4836280B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58092704P 2004-06-18 2004-06-18
US60/580,927 2004-06-18
PCT/US2005/022062 WO2006002236A1 (en) 2004-06-18 2005-06-20 N- (1- (1-benzyl -4-phenyl-1h-imidazol-2-yl) -2,2-dymethylpropyl) benzamide derivatives and related compounds as kinesin spindle protein (ksp) inhibitors for the treatment of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011179247A Division JP2011256197A (ja) 2004-06-18 2011-08-18 癌を治療するためのキネシンスピンドルタンパク質（ｋｓｐ）阻害剤としてのｎ−（１−（１−ベンジル−４−フェニル−１ｈ−イミダゾール−２−イル）−２，２−ジメチルプロピル）ベンズアミド誘導体および関連化合物

Publications (3)

Publication Number Publication Date
JP2008503501A JP2008503501A (ja) 2008-02-07
JP2008503501A5 true JP2008503501A5 (https=) 2008-08-14
JP4836280B2 JP4836280B2 (ja) 2011-12-14

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ID=34980173

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007516842A Expired - Fee Related JP4836280B2 (ja) 2004-06-18 2005-06-20 癌を治療するためのキネシンスピンドルタンパク質（ｋｓｐ）阻害剤としてのｎ−（１−（１−ベンジル−４−フェニル−１ｈ−イミダゾール−２−イル）−２，２−ジメチルプロピル）ベンズアミド誘導体および関連化合物
JP2011179247A Withdrawn JP2011256197A (ja) 2004-06-18 2011-08-18 癌を治療するためのキネシンスピンドルタンパク質（ｋｓｐ）阻害剤としてのｎ−（１−（１−ベンジル−４−フェニル−１ｈ−イミダゾール−２−イル）−２，２−ジメチルプロピル）ベンズアミド誘導体および関連化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011179247A Withdrawn JP2011256197A (ja) 2004-06-18 2011-08-18 癌を治療するためのキネシンスピンドルタンパク質（ｋｓｐ）阻害剤としてのｎ−（１−（１−ベンジル−４−フェニル−１ｈ−イミダゾール−２−イル）−２，２−ジメチルプロピル）ベンズアミド誘導体および関連化合物

Country Status (21)

Country Link
US (3) US7576221B2 (https=)
EP (1) EP1765789B1 (https=)
JP (2) JP4836280B2 (https=)
KR (1) KR101170925B1 (https=)
CN (1) CN1993331A (https=)
AU (1) AU2005258135B2 (https=)
BR (1) BRPI0510929A (https=)
CA (1) CA2571002A1 (https=)
EC (1) ECSP077183A (https=)
ES (1) ES2409345T3 (https=)
IL (1) IL180147A0 (https=)
MA (1) MA28739B1 (https=)
MX (1) MXPA06014909A (https=)
NO (1) NO20070343L (https=)
NZ (1) NZ552510A (https=)
RU (1) RU2427572C2 (https=)
SG (1) SG153851A1 (https=)
TN (1) TNSN06419A1 (https=)
TW (1) TW200612958A (https=)
WO (1) WO2006002236A1 (https=)
ZA (1) ZA200700481B (https=)

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WO2016207094A1 (de) 2015-06-23 2016-12-29 Bayer Pharma Aktiengesellschaft Antikörper-wirkstoff-konjugate (adcs) von ksp-inhibitoren mit anti-tweakr-antikörpern
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JP7066714B2 (ja) 2016-12-21 2022-05-13 バイエル・ファルマ・アクティエンゲゼルシャフト 酵素的に切断可能な基を有する抗体薬物コンジュゲート（ａｄｃ）
JP7030811B2 (ja) 2016-12-21 2022-03-07 バイエル・ファルマ・アクティエンゲゼルシャフト Ｋｓｐ阻害剤を有する特異的抗体－薬物コンジュゲート（ａｄｃ）
JP2021527640A (ja) 2018-06-18 2021-10-14 バイエル アクチェンゲゼルシャフトＢａｙｅｒ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 酵素的に切断可能なリンカーおよび改善された活性プロファイルを有する、ｃｘｃｒ５に対して向けられるバインダー／活性薬剤複合体
TWI844602B (zh) 2018-12-20 2024-06-11 美商安進公司 Kif18a抑制劑
CN119241504A (zh) 2021-08-26 2025-01-03 沃拉斯查疗法公司 Kif18a的螺吲哚啉抑制剂

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