MA28739B1 - Derives de n-(1-(1-benzyl-4-phenyl-1h-imidazol-2-yl)-2,2-dymethylpropyl) benzamide et composes associes comme inhibiteurs de la proteine kinesine fuseau (ksp) pour le traitement du cancer - Google Patents
Derives de n-(1-(1-benzyl-4-phenyl-1h-imidazol-2-yl)-2,2-dymethylpropyl) benzamide et composes associes comme inhibiteurs de la proteine kinesine fuseau (ksp) pour le traitement du cancerInfo
- Publication number
- MA28739B1 MA28739B1 MA29617A MA29617A MA28739B1 MA 28739 B1 MA28739 B1 MA 28739B1 MA 29617 A MA29617 A MA 29617A MA 29617 A MA29617 A MA 29617A MA 28739 B1 MA28739 B1 MA 28739B1
- Authority
- MA
- Morocco
- Prior art keywords
- dymethylpropyl
- ksp
- imidazol
- fungal
- inhibitors
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58092704P | 2004-06-18 | 2004-06-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA28739B1 true MA28739B1 (fr) | 2007-07-02 |
Family
ID=34980173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA29617A MA28739B1 (fr) | 2004-06-18 | 2007-01-17 | Derives de n-(1-(1-benzyl-4-phenyl-1h-imidazol-2-yl)-2,2-dymethylpropyl) benzamide et composes associes comme inhibiteurs de la proteine kinesine fuseau (ksp) pour le traitement du cancer |
Country Status (21)
Country | Link |
---|---|
US (3) | US7576221B2 (fr) |
EP (1) | EP1765789B1 (fr) |
JP (2) | JP4836280B2 (fr) |
KR (1) | KR101170925B1 (fr) |
CN (1) | CN1993331A (fr) |
AU (1) | AU2005258135B2 (fr) |
BR (1) | BRPI0510929A (fr) |
CA (1) | CA2571002A1 (fr) |
EC (1) | ECSP077183A (fr) |
ES (1) | ES2409345T3 (fr) |
IL (1) | IL180147A0 (fr) |
MA (1) | MA28739B1 (fr) |
MX (1) | MXPA06014909A (fr) |
NO (1) | NO20070343L (fr) |
NZ (1) | NZ552510A (fr) |
RU (1) | RU2427572C2 (fr) |
SG (1) | SG153851A1 (fr) |
TN (1) | TNSN06419A1 (fr) |
TW (1) | TW200612958A (fr) |
WO (1) | WO2006002236A1 (fr) |
ZA (1) | ZA200700481B (fr) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
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MXPA06014909A (es) * | 2004-06-18 | 2007-02-28 | Chiron Corp | Derivados de n-(1-(1-bencil -4-fenil-1h -imidazol -2-il)-2, 2-dimetilpropil) benzamida y compuestos relacionados como inhibidores de proteina de huso de cinesina (ksp) para el tratamiento del cancer. |
BRPI0514390A (pt) | 2004-08-18 | 2008-06-10 | Astrazeneca Ab | enanciÈmero de um composto ou um sal farmacêuticamente aceitável ou um éster hidrolisável in vivo do mesmo, uso do mesmo, métodos para o tratamento de cáncer, para produzir um efeito inibidor de eg5 em um animal de sangue quente e para tratar doenças, e, composição farmacêutica |
WO2007011647A2 (fr) * | 2005-07-15 | 2007-01-25 | Kalypsys, Inc. | Inhibiteurs de la kinesine mitotique |
MY147188A (en) * | 2005-08-09 | 2012-11-14 | Novartis Ag | Substituted imidazole compounds as ksp inhibitors |
US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
TW200813039A (en) | 2006-04-19 | 2008-03-16 | Novartis Ag | 6-O-substituted benzoxazole and benzothiazole compounds and methods of inhibiting CSF-1R signaling |
WO2008029825A1 (fr) * | 2006-09-05 | 2008-03-13 | Kyowa Hakko Kirin Co., Ltd. | Dérivé d'imidazole |
SG175609A1 (en) | 2006-10-09 | 2011-11-28 | Takeda Pharmaceutical | Kinase inhibitors |
EP2091926B1 (fr) | 2006-11-13 | 2015-10-21 | Novartis AG | Composés de pyrazole et de triazole substitués comme inhibiteurs de ksp |
CN101622247A (zh) * | 2007-01-05 | 2010-01-06 | 诺瓦提斯公司 | 作为驱动蛋白纺锤体蛋白抑制剂的咪唑衍生物 |
US8252832B2 (en) | 2007-12-14 | 2012-08-28 | Novartis Ag | Kinesin inhibitors as cancer therapeutics |
EP2389363A1 (fr) | 2009-01-26 | 2011-11-30 | Novartis AG | Sels et polymorphes d'un composé inhibiteur de la kinésine |
AU2011239977B2 (en) * | 2010-04-15 | 2014-11-27 | Novartis Ag | Triazole compounds as KSP inhibitors |
CN103153970A (zh) * | 2010-04-15 | 2013-06-12 | 诺瓦提斯公司 | 作为ksp抑制剂的*唑和噻唑化合物 |
DE102010025663A1 (de) | 2010-06-30 | 2012-01-05 | Karl-Heinz Glüsenkamp | Neue beta-Aminoaldehyd-Derivate, Verfahren zu ihrer Herstellung und ihre chemische Verwendung als reaktive Intermediate |
US8809372B2 (en) | 2011-09-30 | 2014-08-19 | Asana Biosciences, Llc | Pyridine derivatives |
EP2968591A1 (fr) * | 2013-03-15 | 2016-01-20 | Novartis AG | Inhibiteurs de la prolifération cellulaire et leurs conjugués |
US9498540B2 (en) | 2013-03-15 | 2016-11-22 | Novartis Ag | Cell proliferation inhibitors and conjugates thereof |
CA2934617A1 (fr) * | 2013-12-23 | 2015-07-02 | Bayer Pharma Aktiengesellschaft | Conjugues de liant (conjugue anticorps-medicament) comprenant des inhibiteurs de la proteine kinesine du fuseau |
US10786578B2 (en) | 2014-08-05 | 2020-09-29 | Novartis Ag | CKIT antibody drug conjugates |
CN107635586B (zh) * | 2014-12-15 | 2021-09-24 | 拜耳医药股份有限公司 | Ksp抑制剂与无糖基化抗-tweakr抗体的抗体-药物缀合物(adc) |
IS2977B (is) | 2015-02-23 | 2017-07-15 | Actavis Group Ptc Ehf. | Aðferð til framleiðslu á milliefnum sem eru nytsamleg við nýsmíði á elúxadólíni |
JP6971858B2 (ja) | 2015-06-22 | 2021-11-24 | バイエル ファーマ アクチエンゲゼルシャフト | 酵素開裂性基を有する抗体薬物複合体(adc)および抗体プロドラッグ複合体(apdc) |
CA2990394A1 (fr) | 2015-06-23 | 2016-12-29 | Bayer Pharma Aktiengesellschaft | Conjugues anticorps-principe actif (adc) d'inhibiteurs de ksp avec des anticorps anti-tweakr |
WO2016207104A1 (fr) | 2015-06-23 | 2016-12-29 | Bayer Pharma Aktiengesellschaft | Conjugués anticorps-principe actif (adc) d'inhibiteurs de ksp avec des anticorps anti-b7h3 |
MX2017017138A (es) * | 2015-06-23 | 2018-04-30 | Bayer Pharma AG | Conjugados homogeneos especificos de sitio con inhibidores de ksp. |
CN109310781B (zh) | 2016-06-15 | 2024-06-18 | 拜耳制药股份公司 | 具有ksp抑制剂和抗-cd123-抗体的特异性抗体-药物-缀合物(adc) |
JP7066714B2 (ja) | 2016-12-21 | 2022-05-13 | バイエル・ファルマ・アクティエンゲゼルシャフト | 酵素的に切断可能な基を有する抗体薬物コンジュゲート(adc) |
EP3558387B1 (fr) | 2016-12-21 | 2021-10-20 | Bayer Pharma Aktiengesellschaft | Conjugués anticorps-principe actif (adc) spécifiques renfermant des inhibiteurs de ksp |
WO2019243159A1 (fr) | 2018-06-18 | 2019-12-26 | Bayer Aktiengesellschaft | Conjugués liant-principe actif inhibant cxcr5 comprenant des éléments de liaison pouvant être fragmentés de manière enzymatique et présentant un profil d'action amélioré |
MX2021007156A (es) * | 2018-12-20 | 2021-08-16 | Amgen Inc | Inhibidores de kif18a. |
CA3230123A1 (fr) | 2021-08-26 | 2023-03-02 | Derek A. Cogan | Inhibiteurs spiro-indoliniques de la kif18a |
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-
2005
- 2005-06-20 MX MXPA06014909A patent/MXPA06014909A/es active IP Right Grant
- 2005-06-20 ES ES05760871T patent/ES2409345T3/es active Active
- 2005-06-20 WO PCT/US2005/022062 patent/WO2006002236A1/fr active Application Filing
- 2005-06-20 CA CA002571002A patent/CA2571002A1/fr not_active Abandoned
- 2005-06-20 NZ NZ552510A patent/NZ552510A/en not_active IP Right Cessation
- 2005-06-20 RU RU2007101612/04A patent/RU2427572C2/ru not_active IP Right Cessation
- 2005-06-20 JP JP2007516842A patent/JP4836280B2/ja not_active Expired - Fee Related
- 2005-06-20 KR KR1020077000979A patent/KR101170925B1/ko not_active IP Right Cessation
- 2005-06-20 US US11/158,574 patent/US7576221B2/en not_active Expired - Fee Related
- 2005-06-20 SG SG200904294-6A patent/SG153851A1/en unknown
- 2005-06-20 CN CNA2005800262037A patent/CN1993331A/zh active Pending
- 2005-06-20 TW TW094120475A patent/TW200612958A/zh unknown
- 2005-06-20 AU AU2005258135A patent/AU2005258135B2/en not_active Ceased
- 2005-06-20 EP EP05760871A patent/EP1765789B1/fr not_active Not-in-force
- 2005-06-20 BR BRPI0510929-9A patent/BRPI0510929A/pt not_active IP Right Cessation
-
2006
- 2006-12-18 TN TNP2006000419A patent/TNSN06419A1/en unknown
- 2006-12-18 IL IL180147A patent/IL180147A0/en unknown
-
2007
- 2007-01-16 ZA ZA200700481A patent/ZA200700481B/xx unknown
- 2007-01-17 MA MA29617A patent/MA28739B1/fr unknown
- 2007-01-18 EC EC2007007183A patent/ECSP077183A/es unknown
- 2007-01-18 NO NO20070343A patent/NO20070343L/no not_active Application Discontinuation
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2009
- 2009-06-05 US US12/455,798 patent/US8318791B2/en not_active Expired - Fee Related
-
2011
- 2011-08-18 JP JP2011179247A patent/JP2011256197A/ja not_active Withdrawn
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- 2012-09-13 US US13/613,977 patent/US8735599B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7576221B2 (en) | 2009-08-18 |
RU2427572C2 (ru) | 2011-08-27 |
JP2008503501A (ja) | 2008-02-07 |
CN1993331A (zh) | 2007-07-04 |
EP1765789A1 (fr) | 2007-03-28 |
IL180147A0 (en) | 2007-06-03 |
TNSN06419A1 (en) | 2008-02-22 |
TW200612958A (en) | 2006-05-01 |
JP4836280B2 (ja) | 2011-12-14 |
SG153851A1 (en) | 2009-07-29 |
ECSP077183A (es) | 2007-02-28 |
KR101170925B1 (ko) | 2012-08-07 |
JP2011256197A (ja) | 2011-12-22 |
MXPA06014909A (es) | 2007-02-28 |
BRPI0510929A (pt) | 2007-07-17 |
KR20070106961A (ko) | 2007-11-06 |
CA2571002A1 (fr) | 2006-01-05 |
ES2409345T3 (es) | 2013-06-26 |
US8318791B2 (en) | 2012-11-27 |
RU2007101612A (ru) | 2008-08-10 |
US20090258016A1 (en) | 2009-10-15 |
US20130017196A1 (en) | 2013-01-17 |
NO20070343L (no) | 2007-03-05 |
US20060009472A1 (en) | 2006-01-12 |
ZA200700481B (en) | 2008-10-29 |
AU2005258135A1 (en) | 2006-01-05 |
US8735599B2 (en) | 2014-05-27 |
EP1765789B1 (fr) | 2013-02-27 |
WO2006002236A1 (fr) | 2006-01-05 |
NZ552510A (en) | 2010-12-24 |
AU2005258135B2 (en) | 2011-09-22 |
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