JP2008501802A5 - - Google Patents
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- Publication number
- JP2008501802A5 JP2008501802A5 JP2007527639A JP2007527639A JP2008501802A5 JP 2008501802 A5 JP2008501802 A5 JP 2008501802A5 JP 2007527639 A JP2007527639 A JP 2007527639A JP 2007527639 A JP2007527639 A JP 2007527639A JP 2008501802 A5 JP2008501802 A5 JP 2008501802A5
- Authority
- JP
- Japan
- Prior art keywords
- solid dispersion
- pharmaceutical composition
- polymer
- amorphous
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57804304P | 2004-06-08 | 2004-06-08 | |
| PCT/US2005/019929 WO2005123076A2 (en) | 2004-06-08 | 2005-06-08 | Pharmaceutical compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012000814A Division JP5337262B2 (ja) | 2004-06-08 | 2012-01-05 | 医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008501802A JP2008501802A (ja) | 2008-01-24 |
| JP2008501802A5 true JP2008501802A5 (enExample) | 2008-07-24 |
Family
ID=35510250
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007527639A Pending JP2008501802A (ja) | 2004-06-08 | 2005-06-08 | 医薬組成物 |
| JP2012000814A Expired - Fee Related JP5337262B2 (ja) | 2004-06-08 | 2012-01-05 | 医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012000814A Expired - Fee Related JP5337262B2 (ja) | 2004-06-08 | 2012-01-05 | 医薬組成物 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20060089385A1 (enExample) |
| EP (1) | EP1765283A4 (enExample) |
| JP (2) | JP2008501802A (enExample) |
| KR (2) | KR101370580B1 (enExample) |
| CN (2) | CN1988885A (enExample) |
| AR (1) | AR049297A1 (enExample) |
| AU (1) | AU2005253957B2 (enExample) |
| BR (1) | BRPI0511900A (enExample) |
| CA (1) | CA2569310A1 (enExample) |
| IL (2) | IL179809A (enExample) |
| MX (1) | MXPA06014253A (enExample) |
| NO (1) | NO20070130L (enExample) |
| NZ (1) | NZ588471A (enExample) |
| RU (1) | RU2373923C2 (enExample) |
| SG (1) | SG153800A1 (enExample) |
| TW (1) | TWI389688B (enExample) |
| WO (1) | WO2005123076A2 (enExample) |
| ZA (2) | ZA200700030B (enExample) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ335276A (en) * | 1996-10-18 | 2000-09-29 | Vertex Pharma | Inhibitors of serine proteases, particularly hepatitis C virus (HCV) NS3 (Non Structural Protein 3) protease |
| SV2003000617A (es) * | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
| MY169670A (en) | 2003-09-03 | 2019-05-08 | Tibotec Pharm Ltd | Combinations of a pyrimidine containing nnrti with rt inhibitors |
| MY148123A (en) * | 2003-09-05 | 2013-02-28 | Vertex Pharma | Inhibitors of serine proteases, particularly hcv ns3-ns4a protease |
| MY141025A (en) | 2004-10-29 | 2010-02-25 | Vertex Pharma | Dose forms |
| US8119602B2 (en) | 2005-06-02 | 2012-02-21 | Schering Corporation | Administration of HCV protease inhibitors in combination with food to improve bioavailability |
| US7772178B2 (en) | 2005-06-02 | 2010-08-10 | Schering Corporation | Pharmaceutical formulations and methods of treatment using the same |
| ES2401661T3 (es) * | 2005-08-02 | 2013-04-23 | Vertex Pharmaceuticals Incorporated | Inhibidores de serina proteasas |
| US8399615B2 (en) | 2005-08-19 | 2013-03-19 | Vertex Pharmaceuticals Incorporated | Processes and intermediates |
| US7964624B1 (en) | 2005-08-26 | 2011-06-21 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
| AR055395A1 (es) * | 2005-08-26 | 2007-08-22 | Vertex Pharma | Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c |
| EP1991229A2 (en) | 2006-02-27 | 2008-11-19 | Vertex Pharmaceuticals Incorporated | Co-crystals and pharmaceutical compositions comprising the same |
| CA2645684A1 (en) * | 2006-03-06 | 2007-09-13 | Abbott Laboratories | Compositions and methods of use of ritonavir for treating hcv |
| JP2009531315A (ja) | 2006-03-16 | 2009-09-03 | バーテックス ファーマシューティカルズ インコーポレイテッド | 重水素化c型肝炎プロテアーゼインヒビター |
| JP2009530415A (ja) * | 2006-03-20 | 2009-08-27 | バーテックス ファーマシューティカルズ インコーポレイテッド | 医薬組成物 |
| WO2007109605A2 (en) * | 2006-03-20 | 2007-09-27 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions |
| EP2518079A3 (en) | 2006-04-11 | 2012-12-12 | Novartis AG | HCV/HIV inhibitors and their uses |
| WO2007120595A2 (en) * | 2006-04-11 | 2007-10-25 | Novartis Ag | Amines for the treatment of hcv |
| MX2009006806A (es) * | 2006-12-22 | 2009-08-27 | Vertex Pharma | Secado por rocio fluidizado. |
| WO2008074035A1 (en) | 2006-12-27 | 2008-06-19 | Abbott Laboratories | Hcv protease inhibitors and uses thereof |
| JP2010519312A (ja) * | 2007-02-23 | 2010-06-03 | アベラ ファーマシューティカルズ, インコーポレイテッド | 薬学的製剤 |
| EA200970806A1 (ru) * | 2007-02-27 | 2010-08-30 | Вертекс Фармасьютикалз Инкорпорейтед | Сокристаллы и содержащие их фармацевтические композиции |
| US8575208B2 (en) * | 2007-02-27 | 2013-11-05 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
| AR065720A1 (es) * | 2007-03-14 | 2009-06-24 | Tibotec Pharm Ltd | Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso. |
| PL2305263T3 (pl) * | 2007-06-07 | 2012-12-31 | Novartis Ag | Stabilizowane amorficzne formy mesylanu imatinibu |
| EP2436682A1 (en) * | 2007-08-30 | 2012-04-04 | Vertex Pharmceuticals Incorporated | Co-crystals and pharmaceutical compositions comprising the same |
| JP5161528B2 (ja) * | 2007-10-02 | 2013-03-13 | 浜松ホトニクス株式会社 | パクリタキセル微粒子、パクリタキセル微粒子分散液、および、これらの製造方法 |
| JP5149585B2 (ja) * | 2007-10-02 | 2013-02-20 | 浜松ホトニクス株式会社 | 微粒子分散液製造方法 |
| KR101396696B1 (ko) * | 2007-10-10 | 2014-05-16 | 노파르티스 아게 | 스피로피롤리딘, 및 hcv 및 hiv 감염에 대한 그의 용도 |
| CN101827585A (zh) * | 2007-10-19 | 2010-09-08 | 雅培股份有限两合公司 | 含有n-芳基脲基化合物的固态分散体产品 |
| EP2214682A2 (en) * | 2007-11-05 | 2010-08-11 | Vertex Pharmaceuticals Incorporated | Hcv combination therapies comprising vx-950, peg-ifn and ribavirin |
| US12458635B2 (en) | 2008-08-13 | 2025-11-04 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| KR20110074870A (ko) | 2008-09-24 | 2011-07-04 | 버텍스 파마슈티칼스 인코포레이티드 | 간염을 치료하기 위한 peg-인터페론, 리바비린 및 vx-950을 포함하는 치료 요법 |
| EP2396028A2 (en) | 2009-02-12 | 2011-12-21 | Vertex Pharmceuticals Incorporated | Hcv combination therapies comprising pegylated interferon, ribavirin and telaprevir |
| CA2738573C (en) | 2009-04-03 | 2013-02-19 | F. Hoffmann-La Roche Ag | Compositions of propane-1 sulfonic acid {3-[5-(4-chloro-phenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide and uses thereof |
| US8512690B2 (en) | 2009-04-10 | 2013-08-20 | Novartis Ag | Derivatised proline containing peptide compounds as protease inhibitors |
| US20110027229A1 (en) | 2009-07-31 | 2011-02-03 | Medtronic, Inc. | Continuous subcutaneous administration of interferon-alpha to hepatitis c infected patients |
| US20120329704A1 (en) * | 2010-02-25 | 2012-12-27 | Vereniging Voor Christelijk Hoger Onderwijs Wetenschappelijk Onderzoek En Patieentenzorg | Process for the preparation of substituted prolyl peptides and similar peptidomimetics |
| EP2593105A1 (en) | 2010-07-14 | 2013-05-22 | Vertex Pharmaceuticals Incorporated | Palatable pharmaceutical composition comprising vx-950 |
| WO2012109646A1 (en) | 2011-02-11 | 2012-08-16 | Vertex Pharmaceuticals Incorporated | Treatment of hcv in hiv infection patients |
| WO2012122279A1 (en) * | 2011-03-08 | 2012-09-13 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
| US8409560B2 (en) | 2011-03-08 | 2013-04-02 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| CN104023726A (zh) | 2011-10-21 | 2014-09-03 | 艾伯维公司 | 用于治疗hcv的一种或多种daa的联合治疗(例如,与abt-072或abt-333) |
| DE112012003510T5 (de) | 2011-10-21 | 2015-03-19 | Abbvie Inc. | Verfahren zur Behandlung von HCV umfassend mindestens zwei direkt wirkende antivirale Wirkstoffe, Ribavirin aber nicht Interferon |
| US9034832B2 (en) | 2011-12-29 | 2015-05-19 | Abbvie Inc. | Solid compositions |
| JP5781706B2 (ja) * | 2011-12-29 | 2015-09-24 | アッヴィ・アイルランド・アンリミテッド・カンパニー | Hcv阻害剤を含む固体組成物 |
| US20130195797A1 (en) | 2012-01-31 | 2013-08-01 | Vertex Pharmaceuticals Incorporated | High potency formulations of vx-950 |
| EP2819670B1 (en) | 2012-02-27 | 2026-05-20 | Vertex Pharmaceuticals Incorporated | Pharmaceutical Composition and Their Administration |
| ITMI20120608A1 (it) | 2012-04-13 | 2013-10-14 | Dipharma Francis Srl | Procedimento per la preparazione di un inibitore delle proteasi virali in forma amorfa |
| WO2013178031A1 (en) * | 2012-06-01 | 2013-12-05 | Sunshine Lake Pharma Co., Ltd. | New forms of telaprevir and preparation methods thereof |
| WO2014096343A1 (en) * | 2012-12-21 | 2014-06-26 | Sandoz Ag | Novel forms of telaprevir |
| EP2950786B1 (en) | 2013-01-31 | 2019-11-27 | Gilead Pharmasset LLC | Combination formulation of two antiviral compounds |
| AU2014233705C1 (en) | 2013-03-15 | 2019-10-10 | Boehringer Ingelheim International Gmbh | Solid oral dosage formulation of HCV inhibitor in the amorphous state |
| EA201690473A1 (ru) | 2013-08-27 | 2017-03-31 | ГАЙЛИД ФАРМАССЕТ ЭлЭлСи | Комбинированный состав двух противовирусных соединений |
| JP7129703B2 (ja) | 2016-04-28 | 2022-09-02 | エモリー ユニバーシティー | アルキン含有ヌクレオチド及びヌクレオシド治療組成物並びにそれらに関連した使用 |
| CN110193013B (zh) * | 2019-07-02 | 2022-02-08 | 力品药业(厦门)股份有限公司 | 一种去乙酰真菌环氧乙酯固体分散体及其制备方法 |
| AU2023272583A1 (en) * | 2022-05-16 | 2024-11-21 | Day One Biopharmaceuticals, Inc. | Oral liquid suspension of pan-raf kinase inhibitor |
| TW202428307A (zh) * | 2022-10-12 | 2024-07-16 | 日商中外製藥股份有限公司 | 包含胜肽、界面活性劑及聚合物的組成物 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9109506D0 (en) * | 1991-05-02 | 1991-06-26 | Wellcome Found | Therapeutic nucleosides |
| TW487582B (en) * | 1995-08-11 | 2002-05-21 | Nissan Chemical Ind Ltd | Method for converting sparingly water-soluble medical substance to amorphous state |
| US6054472A (en) * | 1996-04-23 | 2000-04-25 | Vertex Pharmaceuticals, Incorporated | Inhibitors of IMPDH enzyme |
| JPH107558A (ja) * | 1996-06-19 | 1998-01-13 | Eisai Co Ltd | 溶解性改善製剤 |
| PT901786E (pt) * | 1997-08-11 | 2007-08-07 | Pfizer Prod Inc | Disperções farmacêuticas sólidas com biodisponibilidade melhorada |
| US20020017295A1 (en) * | 2000-07-07 | 2002-02-14 | Weers Jeffry G. | Phospholipid-based powders for inhalation |
| EP1027885B1 (en) * | 1999-02-09 | 2008-07-09 | Pfizer Products Inc. | Basic drug compositions with enhanced bioavailability |
| AR028253A1 (es) * | 2000-03-16 | 2003-04-30 | Pfizer Prod Inc | Inhibidores de la glucogeno fosforilasa |
| US6777400B2 (en) * | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| SV2003000617A (es) * | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
| GB0102342D0 (en) * | 2001-01-30 | 2001-03-14 | Smithkline Beecham Plc | Pharmaceutical formulation |
| US6627760B1 (en) * | 2001-06-25 | 2003-09-30 | Astrazeneca Ab | Amorphous compound |
| KR20050044450A (ko) * | 2001-11-14 | 2005-05-12 | 테바 파마슈티컬 인더스트리즈 리미티드 | 로사르탄 칼륨의 무정형 및 결정형 형태 및 이의 제조 방법 |
| AR038375A1 (es) * | 2002-02-01 | 2005-01-12 | Pfizer Prod Inc | Composiciones farmaceuticas de inhibidores de la proteina de transferencia de esteres de colesterilo |
| US6642204B2 (en) * | 2002-02-01 | 2003-11-04 | Boehringer Ingelheim International Gmbh | Hepatitis C inhibitor tri-peptides |
| US6828301B2 (en) * | 2002-02-07 | 2004-12-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for hepatitis C viral protease inhibitors |
| CN1893978A (zh) * | 2003-10-27 | 2007-01-10 | 沃泰克斯药物股份有限公司 | 用于hcv治疗的组合 |
| MY141025A (en) * | 2004-10-29 | 2010-02-25 | Vertex Pharma | Dose forms |
-
2005
- 2005-06-08 WO PCT/US2005/019929 patent/WO2005123076A2/en not_active Ceased
- 2005-06-08 RU RU2006147247/15A patent/RU2373923C2/ru not_active IP Right Cessation
- 2005-06-08 KR KR1020077000437A patent/KR101370580B1/ko not_active Expired - Fee Related
- 2005-06-08 EP EP05757623A patent/EP1765283A4/en not_active Withdrawn
- 2005-06-08 AU AU2005253957A patent/AU2005253957B2/en not_active Ceased
- 2005-06-08 BR BRPI0511900-6A patent/BRPI0511900A/pt not_active IP Right Cessation
- 2005-06-08 AR ARP050102345A patent/AR049297A1/es unknown
- 2005-06-08 MX MXPA06014253A patent/MXPA06014253A/es not_active Application Discontinuation
- 2005-06-08 US US11/147,524 patent/US20060089385A1/en not_active Abandoned
- 2005-06-08 CN CNA200580024232XA patent/CN1988885A/zh active Pending
- 2005-06-08 KR KR1020127008036A patent/KR20120039763A/ko not_active Ceased
- 2005-06-08 CN CN2011103013245A patent/CN102512372A/zh active Pending
- 2005-06-08 NZ NZ588471A patent/NZ588471A/en not_active IP Right Cessation
- 2005-06-08 ZA ZA200700030A patent/ZA200700030B/xx unknown
- 2005-06-08 SG SG200903859-7A patent/SG153800A1/en unknown
- 2005-06-08 JP JP2007527639A patent/JP2008501802A/ja active Pending
- 2005-06-08 TW TW094118847A patent/TWI389688B/zh not_active IP Right Cessation
- 2005-06-08 CA CA002569310A patent/CA2569310A1/en not_active Abandoned
-
2006
- 2006-12-04 IL IL179809A patent/IL179809A/en not_active IP Right Cessation
-
2007
- 2007-01-08 NO NO20070130A patent/NO20070130L/no not_active Application Discontinuation
-
2008
- 2008-03-26 ZA ZA200802676A patent/ZA200802676B/en unknown
-
2012
- 2012-01-05 JP JP2012000814A patent/JP5337262B2/ja not_active Expired - Fee Related
- 2012-09-20 IL IL222003A patent/IL222003A0/en unknown
-
2013
- 2013-04-12 US US13/861,791 patent/US20130274180A1/en not_active Abandoned
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