JP2008501802A5 - - Google Patents
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- Publication number
- JP2008501802A5 JP2008501802A5 JP2007527639A JP2007527639A JP2008501802A5 JP 2008501802 A5 JP2008501802 A5 JP 2008501802A5 JP 2007527639 A JP2007527639 A JP 2007527639A JP 2007527639 A JP2007527639 A JP 2007527639A JP 2008501802 A5 JP2008501802 A5 JP 2008501802A5
- Authority
- JP
- Japan
- Prior art keywords
- solid dispersion
- pharmaceutical composition
- polymer
- amorphous
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57804304P | 2004-06-08 | 2004-06-08 | |
| PCT/US2005/019929 WO2005123076A2 (en) | 2004-06-08 | 2005-06-08 | Pharmaceutical compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012000814A Division JP5337262B2 (ja) | 2004-06-08 | 2012-01-05 | 医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008501802A JP2008501802A (ja) | 2008-01-24 |
| JP2008501802A5 true JP2008501802A5 (enExample) | 2008-07-24 |
Family
ID=35510250
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007527639A Pending JP2008501802A (ja) | 2004-06-08 | 2005-06-08 | 医薬組成物 |
| JP2012000814A Expired - Fee Related JP5337262B2 (ja) | 2004-06-08 | 2012-01-05 | 医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012000814A Expired - Fee Related JP5337262B2 (ja) | 2004-06-08 | 2012-01-05 | 医薬組成物 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20060089385A1 (enExample) |
| EP (1) | EP1765283A4 (enExample) |
| JP (2) | JP2008501802A (enExample) |
| KR (2) | KR20120039763A (enExample) |
| CN (2) | CN1988885A (enExample) |
| AR (1) | AR049297A1 (enExample) |
| AU (1) | AU2005253957B2 (enExample) |
| BR (1) | BRPI0511900A (enExample) |
| CA (1) | CA2569310A1 (enExample) |
| IL (2) | IL179809A (enExample) |
| MX (1) | MXPA06014253A (enExample) |
| NO (1) | NO20070130L (enExample) |
| NZ (1) | NZ588471A (enExample) |
| RU (1) | RU2373923C2 (enExample) |
| SG (1) | SG153800A1 (enExample) |
| TW (1) | TWI389688B (enExample) |
| WO (1) | WO2005123076A2 (enExample) |
| ZA (2) | ZA200700030B (enExample) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69709671T2 (de) * | 1996-10-18 | 2002-08-22 | Vertex Pharmaceuticals Inc., Cambridge | Inhibitoren von serinproteasen, insbesondere von ns3-protease des hepatitis-c-virus |
| SV2003000617A (es) * | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
| MY169670A (en) | 2003-09-03 | 2019-05-08 | Tibotec Pharm Ltd | Combinations of a pyrimidine containing nnrti with rt inhibitors |
| MY148123A (en) * | 2003-09-05 | 2013-02-28 | Vertex Pharma | Inhibitors of serine proteases, particularly hcv ns3-ns4a protease |
| TWI437990B (zh) * | 2004-10-29 | 2014-05-21 | Vertex Pharma | Vx-950之醫藥用途 |
| WO2006130686A2 (en) * | 2005-06-02 | 2006-12-07 | Schering Corporation | Hcv protease inhibitors in combination with food |
| AU2006252553B2 (en) * | 2005-06-02 | 2012-03-29 | Merck Sharp & Dohme Corp. | Combination of HCV protease inhibitors with a surfactant |
| WO2007016589A2 (en) | 2005-08-02 | 2007-02-08 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
| US8399615B2 (en) | 2005-08-19 | 2013-03-19 | Vertex Pharmaceuticals Incorporated | Processes and intermediates |
| US7964624B1 (en) * | 2005-08-26 | 2011-06-21 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
| AR055395A1 (es) * | 2005-08-26 | 2007-08-22 | Vertex Pharma | Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c |
| CA2643688A1 (en) * | 2006-02-27 | 2007-08-30 | Vertex Pharmaceuticals Incorporated | Co-crystals and pharmaceutical compositions comprising the same |
| CN101460166B (zh) * | 2006-03-06 | 2014-11-19 | Abbvie公司 | 用于治疗c型肝炎病毒的利托那韦组合物及其用途 |
| AU2007227544B2 (en) | 2006-03-16 | 2012-11-01 | Vertex Pharmaceuticals Incorporated | Deuterated hepatitis C protease inhibitors |
| AU2007226984B2 (en) * | 2006-03-20 | 2013-02-21 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions |
| AU2007226983A1 (en) * | 2006-03-20 | 2007-09-27 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions |
| WO2007120595A2 (en) * | 2006-04-11 | 2007-10-25 | Novartis Ag | Amines for the treatment of hcv |
| EP2007789B1 (en) | 2006-04-11 | 2015-05-20 | Novartis AG | Spirocyclic HCV/HIV inhibitors and their uses |
| MX2009006806A (es) * | 2006-12-22 | 2009-08-27 | Vertex Pharma | Secado por rocio fluidizado. |
| WO2008074035A1 (en) * | 2006-12-27 | 2008-06-19 | Abbott Laboratories | Hcv protease inhibitors and uses thereof |
| CA2679028A1 (en) * | 2007-02-23 | 2008-08-28 | Avera Pharmaceuticals, Inc. | Pharmaceutical formulation |
| DK2114924T3 (da) * | 2007-02-27 | 2012-04-10 | Vertex Pharma | Co-krystaller og farmaceutiske sammensætninger omfattende disse |
| NZ579295A (en) * | 2007-02-27 | 2012-03-30 | Vertex Pharma | Inhibitors of serine proteases |
| TWI494133B (zh) * | 2007-03-14 | 2015-08-01 | Tibotec Pharm Ltd | 重組用粉末 |
| PL2305263T3 (pl) * | 2007-06-07 | 2012-12-31 | Novartis Ag | Stabilizowane amorficzne formy mesylanu imatinibu |
| TW200922933A (en) * | 2007-08-30 | 2009-06-01 | Vertex Pharma | Co-crystals and pharmaceutical compositions comprising the same |
| JP5161528B2 (ja) * | 2007-10-02 | 2013-03-13 | 浜松ホトニクス株式会社 | パクリタキセル微粒子、パクリタキセル微粒子分散液、および、これらの製造方法 |
| JP5149585B2 (ja) * | 2007-10-02 | 2013-02-20 | 浜松ホトニクス株式会社 | 微粒子分散液製造方法 |
| AU2008309589B2 (en) * | 2007-10-10 | 2012-07-05 | Novartis Ag | Spiropyrrolidines and their use against HCV and HIV infection |
| CA2699335A1 (en) * | 2007-10-19 | 2009-04-23 | Abbott Gmbh & Co. Kg. | Solid dispersion product containing n-aryl urea-based compound |
| EP2214682A2 (en) * | 2007-11-05 | 2010-08-11 | Vertex Pharmaceuticals Incorporated | Hcv combination therapies comprising vx-950, peg-ifn and ribavirin |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| US12458635B2 (en) | 2008-08-13 | 2025-11-04 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| EP2328656A1 (en) * | 2008-09-24 | 2011-06-08 | Vertex Pharmaceuticals Incorporated | Therapeutic regimen comprising peg- interferon, ribavirin and vx-950 for the treatment of hepatitis " |
| JP2012517478A (ja) | 2009-02-12 | 2012-08-02 | バーテックス ファーマシューティカルズ インコーポレイテッド | ペグ化インターフェロン、リバビリンおよびテラプレビルを含む、hcv組合せ治療剤 |
| MY160737A (en) | 2009-04-03 | 2017-03-15 | Hoffmann La Roche | Propane-i-sulfonic acid {3- [5-(4-chloro-phenyl) -1h -pyrrolo [2, 3-b] pyridine-3-carbonyl] -2,4 difluoro-phenyl} - amide compositions and uses thereof |
| US8512690B2 (en) | 2009-04-10 | 2013-08-20 | Novartis Ag | Derivatised proline containing peptide compounds as protease inhibitors |
| US20110027229A1 (en) | 2009-07-31 | 2011-02-03 | Medtronic, Inc. | Continuous subcutaneous administration of interferon-alpha to hepatitis c infected patients |
| WO2011103932A1 (en) * | 2010-02-25 | 2011-09-01 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg | A process for the preparation of substituted prolyl peptides and similar peptidomimetics |
| US20120014912A1 (en) | 2010-07-14 | 2012-01-19 | Vertex Pharmaceuticals Incorporated | Palatable pharmaceutical composition |
| WO2012109646A1 (en) | 2011-02-11 | 2012-08-16 | Vertex Pharmaceuticals Incorporated | Treatment of hcv in hiv infection patients |
| CN103491964A (zh) * | 2011-03-08 | 2014-01-01 | 扎里卡斯药品有限公司 | 固体分散体制剂及其使用方法 |
| US8409560B2 (en) | 2011-03-08 | 2013-04-02 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| CH707030B1 (de) | 2011-10-21 | 2015-03-13 | Abbvie Inc | Kombinationsbehandlung von DAAs zur Verwendung in der Behandlung von HCV |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| ES2529143B1 (es) | 2011-10-21 | 2015-10-26 | Abbvie Inc. | Combinación de al menos dos agentes antivirales de acción directa, ribavirina pero no interferón para uso de tratamiento del vhc |
| EP2907505A3 (en) * | 2011-12-29 | 2015-12-30 | Abbvie Inc. | Solid compositions comprising an HCV inhibitor |
| US9034832B2 (en) | 2011-12-29 | 2015-05-19 | Abbvie Inc. | Solid compositions |
| WO2013116339A1 (en) | 2012-01-31 | 2013-08-08 | Vertex Pharmaceuticals Incorporated | High potency formulations of vx-950 |
| RU2692779C2 (ru) | 2012-02-27 | 2019-06-27 | Вертекс Фармасьютикалз Инкорпорейтед | Фармацевтическая композиция и ее введения |
| ITMI20120608A1 (it) * | 2012-04-13 | 2013-10-14 | Dipharma Francis Srl | Procedimento per la preparazione di un inibitore delle proteasi virali in forma amorfa |
| WO2013178031A1 (en) * | 2012-06-01 | 2013-12-05 | Sunshine Lake Pharma Co., Ltd. | New forms of telaprevir and preparation methods thereof |
| EP2935245A1 (en) * | 2012-12-21 | 2015-10-28 | Sandoz AG | Novel forms of telaprevir |
| SG11201506021XA (en) | 2013-01-31 | 2015-08-28 | Gilead Pharmasset Llc | Combination formulation of two antiviral compounds |
| US9732076B2 (en) | 2013-03-15 | 2017-08-15 | Boehringer Ingelheim International Gmbh | Solid oral dosage formulation of HCV inhibitor in the amorphous state |
| JP2016529293A (ja) | 2013-08-27 | 2016-09-23 | ギリアド ファーマセット エルエルシー | 2つの抗ウイルス化合物の組合せ製剤 |
| EP3448392A4 (en) | 2016-04-28 | 2020-01-15 | Emory University | ALKYNOUS THERAPEUTIC NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND RELATED APPLICATIONS |
| CN110193013B (zh) * | 2019-07-02 | 2022-02-08 | 力品药业(厦门)股份有限公司 | 一种去乙酰真菌环氧乙酯固体分散体及其制备方法 |
| WO2023225029A1 (en) * | 2022-05-16 | 2023-11-23 | Day One Biopharmaceuticals, Inc. | Oral liquid suspension of pan-raf kinase inhibitor |
| WO2024080308A1 (ja) * | 2022-10-12 | 2024-04-18 | 中外製薬株式会社 | ペプチド、界面活性剤及びポリマーを含む組成物 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9109506D0 (en) * | 1991-05-02 | 1991-06-26 | Wellcome Found | Therapeutic nucleosides |
| TW487582B (en) * | 1995-08-11 | 2002-05-21 | Nissan Chemical Ind Ltd | Method for converting sparingly water-soluble medical substance to amorphous state |
| US6054472A (en) * | 1996-04-23 | 2000-04-25 | Vertex Pharmaceuticals, Incorporated | Inhibitors of IMPDH enzyme |
| JPH107558A (ja) * | 1996-06-19 | 1998-01-13 | Eisai Co Ltd | 溶解性改善製剤 |
| ATE364374T1 (de) * | 1997-08-11 | 2007-07-15 | Pfizer Prod Inc | Feste pharmazeutische dispersionen mit erhöhter bioverfügbarkeit |
| US20020017295A1 (en) * | 2000-07-07 | 2002-02-14 | Weers Jeffry G. | Phospholipid-based powders for inhalation |
| ATE400251T1 (de) * | 1999-02-09 | 2008-07-15 | Pfizer Prod Inc | Zusammensetzungen basischer arzneistoffe mit verbesserter bioverfügbarkeit |
| AR028253A1 (es) * | 2000-03-16 | 2003-04-30 | Pfizer Prod Inc | Inhibidores de la glucogeno fosforilasa |
| US6777400B2 (en) * | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| SV2003000617A (es) * | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
| GB0102342D0 (en) * | 2001-01-30 | 2001-03-14 | Smithkline Beecham Plc | Pharmaceutical formulation |
| US6627760B1 (en) * | 2001-06-25 | 2003-09-30 | Astrazeneca Ab | Amorphous compound |
| PL374442A1 (en) * | 2001-11-14 | 2005-10-17 | Teva Pharmaceutical Industries Ltd. | Amorphous and crystalline forms of losartan potassium and process for their preparation |
| AR038375A1 (es) * | 2002-02-01 | 2005-01-12 | Pfizer Prod Inc | Composiciones farmaceuticas de inhibidores de la proteina de transferencia de esteres de colesterilo |
| US6642204B2 (en) * | 2002-02-01 | 2003-11-04 | Boehringer Ingelheim International Gmbh | Hepatitis C inhibitor tri-peptides |
| US6828301B2 (en) * | 2002-02-07 | 2004-12-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for hepatitis C viral protease inhibitors |
| US20060003942A1 (en) * | 2003-10-27 | 2006-01-05 | Roger Tung | Combinations for HCV treatment |
| TWI437990B (zh) * | 2004-10-29 | 2014-05-21 | Vertex Pharma | Vx-950之醫藥用途 |
-
2005
- 2005-06-08 AR ARP050102345A patent/AR049297A1/es unknown
- 2005-06-08 BR BRPI0511900-6A patent/BRPI0511900A/pt not_active IP Right Cessation
- 2005-06-08 US US11/147,524 patent/US20060089385A1/en not_active Abandoned
- 2005-06-08 KR KR1020127008036A patent/KR20120039763A/ko not_active Ceased
- 2005-06-08 EP EP05757623A patent/EP1765283A4/en not_active Withdrawn
- 2005-06-08 ZA ZA200700030A patent/ZA200700030B/xx unknown
- 2005-06-08 MX MXPA06014253A patent/MXPA06014253A/es not_active Application Discontinuation
- 2005-06-08 KR KR1020077000437A patent/KR101370580B1/ko not_active Expired - Fee Related
- 2005-06-08 CN CNA200580024232XA patent/CN1988885A/zh active Pending
- 2005-06-08 WO PCT/US2005/019929 patent/WO2005123076A2/en not_active Ceased
- 2005-06-08 CN CN2011103013245A patent/CN102512372A/zh active Pending
- 2005-06-08 SG SG200903859-7A patent/SG153800A1/en unknown
- 2005-06-08 NZ NZ588471A patent/NZ588471A/en not_active IP Right Cessation
- 2005-06-08 CA CA002569310A patent/CA2569310A1/en not_active Abandoned
- 2005-06-08 AU AU2005253957A patent/AU2005253957B2/en not_active Ceased
- 2005-06-08 JP JP2007527639A patent/JP2008501802A/ja active Pending
- 2005-06-08 RU RU2006147247/15A patent/RU2373923C2/ru not_active IP Right Cessation
- 2005-06-08 TW TW094118847A patent/TWI389688B/zh not_active IP Right Cessation
-
2006
- 2006-12-04 IL IL179809A patent/IL179809A/en not_active IP Right Cessation
-
2007
- 2007-01-08 NO NO20070130A patent/NO20070130L/no not_active Application Discontinuation
-
2008
- 2008-03-26 ZA ZA200802676A patent/ZA200802676B/en unknown
-
2012
- 2012-01-05 JP JP2012000814A patent/JP5337262B2/ja not_active Expired - Fee Related
- 2012-09-20 IL IL222003A patent/IL222003A0/en unknown
-
2013
- 2013-04-12 US US13/861,791 patent/US20130274180A1/en not_active Abandoned
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