JP2008278887A5 - - Google Patents

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Publication number
JP2008278887A5
JP2008278887A5 JP2008109843A JP2008109843A JP2008278887A5 JP 2008278887 A5 JP2008278887 A5 JP 2008278887A5 JP 2008109843 A JP2008109843 A JP 2008109843A JP 2008109843 A JP2008109843 A JP 2008109843A JP 2008278887 A5 JP2008278887 A5 JP 2008278887A5
Authority
JP
Japan
Prior art keywords
antibody
polypeptide
amino acid
nucleotide sequence
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008109843A
Other languages
English (en)
Japanese (ja)
Other versions
JP5070117B2 (ja
JP2008278887A (ja
Filing date
Publication date
Priority claimed from PCT/US1999/031274 external-priority patent/WO2000053752A2/en
Priority claimed from PCT/US2000/004341 external-priority patent/WO2000053756A2/en
Priority claimed from PCT/US2000/005841 external-priority patent/WO2000053758A2/en
Priority claimed from PCT/US2000/007532 external-priority patent/WO2000070050A1/en
Priority claimed from PCT/US2000/015264 external-priority patent/WO2000073452A2/en
Priority claimed from PCT/US2000/023328 external-priority patent/WO2001016318A2/en
Priority claimed from PCT/US2000/030873 external-priority patent/WO2001040465A2/en
Priority claimed from PCT/US2000/032678 external-priority patent/WO2001040466A2/en
Application filed filed Critical
Publication of JP2008278887A publication Critical patent/JP2008278887A/ja
Publication of JP2008278887A5 publication Critical patent/JP2008278887A5/ja
Publication of JP5070117B2 publication Critical patent/JP5070117B2/ja
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2008109843A 1999-12-23 2008-04-21 Il−17相同的ポリペプチドとその治療上の用途 Expired - Fee Related JP5070117B2 (ja)

Applications Claiming Priority (30)

Application Number Priority Date Filing Date Title
US17209699P 1999-12-23 1999-12-23
US60/172,096 1999-12-23
PCT/US1999/031274 WO2000053752A2 (en) 1999-03-08 1999-12-30 Promotion or inhibition of angiogenesis and cardiovascularization
USPCT/US99/31274 1999-12-30
US17548100P 2000-01-11 2000-01-11
US60/175,481 2000-01-11
USPCT/US00/04341 2000-02-18
PCT/US2000/004341 WO2000053756A2 (en) 1999-03-08 2000-02-18 Secreted and transmembrane polypeptides and nucleic acids encoding the same
USPCT/US00/05841 2000-03-02
PCT/US2000/005841 WO2000053758A2 (en) 1999-03-08 2000-03-02 Compositions and methods for the treatment of immune related diseases
US19100700P 2000-03-21 2000-03-21
PCT/US2000/007532 WO2000070050A1 (en) 1999-05-14 2000-03-21 Compositions and methods for the treatment of immune related diseases
US60/191,007 2000-03-21
USPCT/US00/07532 2000-03-21
USPCT/US00/15264 2000-06-02
PCT/US2000/015264 WO2000073452A2 (en) 1999-06-02 2000-06-02 Compositions and methods for the treatment of immune related diseases
US21380700P 2000-06-22 2000-06-22
US60/213,087 2000-06-22
US64484800A 2000-08-22 2000-08-22
US09/644,848 2000-08-22
USPCT/US00/23328 2000-08-24
PCT/US2000/023328 WO2001016318A2 (en) 1999-09-01 2000-08-24 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US24283700P 2000-10-24 2000-10-24
US60/242,837 2000-10-24
PCT/US2000/030873 WO2001040465A2 (en) 1999-11-30 2000-11-10 Compositions and methods for the treatment of immune related diseases
USPCT/US00/30873 2000-11-10
US25364600P 2000-11-28 2000-11-28
US60/253,646 2000-11-28
USPCT/US00/32678 2000-12-01
PCT/US2000/032678 WO2001040466A2 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2005143079A Division JP2005323597A (ja) 1999-12-23 2005-05-16 Il−17相同的ポリペプチドとその治療上の用途

Publications (3)

Publication Number Publication Date
JP2008278887A JP2008278887A (ja) 2008-11-20
JP2008278887A5 true JP2008278887A5 (enExample) 2009-04-09
JP5070117B2 JP5070117B2 (ja) 2012-11-07

Family

ID=40140243

Family Applications (10)

Application Number Title Priority Date Filing Date
JP2008109843A Expired - Fee Related JP5070117B2 (ja) 1999-12-23 2008-04-21 Il−17相同的ポリペプチドとその治療上の用途
JP2009023863A Pending JP2009159968A (ja) 1999-12-23 2009-02-04 Il−17相同的ポリペプチドとその治療上の用途
JP2009171169A Expired - Lifetime JP5258691B2 (ja) 1999-12-23 2009-07-22 Il−17相同的ポリペプチドとその治療上の用途
JP2010152694A Pending JP2010266454A (ja) 1999-12-23 2010-07-05 Il−17相同的ポリペプチドとその治療上の用途
JP2012012914A Pending JP2012115275A (ja) 1999-12-23 2012-01-25 Il−17相同的ポリペプチドとその治療上の用途
JP2012063772A Pending JP2012152218A (ja) 1999-12-23 2012-03-21 Il−17相同的ポリペプチドとその治療上の用途
JP2013038690A Withdrawn JP2013165712A (ja) 1999-12-23 2013-02-28 Il−17相同的ポリペプチドとその治療上の用途
JP2014138440A Pending JP2014239685A (ja) 1999-12-23 2014-07-04 Il−17相同的ポリペプチドとその治療上の用途
JP2014166220A Pending JP2015007091A (ja) 1999-12-23 2014-08-18 Il−17相同的ポリペプチドとその治療上の用途
JP2014243369A Withdrawn JP2015077137A (ja) 1999-12-23 2014-12-01 Il−17相同的ポリペプチドとその治療上の用途

Family Applications After (9)

Application Number Title Priority Date Filing Date
JP2009023863A Pending JP2009159968A (ja) 1999-12-23 2009-02-04 Il−17相同的ポリペプチドとその治療上の用途
JP2009171169A Expired - Lifetime JP5258691B2 (ja) 1999-12-23 2009-07-22 Il−17相同的ポリペプチドとその治療上の用途
JP2010152694A Pending JP2010266454A (ja) 1999-12-23 2010-07-05 Il−17相同的ポリペプチドとその治療上の用途
JP2012012914A Pending JP2012115275A (ja) 1999-12-23 2012-01-25 Il−17相同的ポリペプチドとその治療上の用途
JP2012063772A Pending JP2012152218A (ja) 1999-12-23 2012-03-21 Il−17相同的ポリペプチドとその治療上の用途
JP2013038690A Withdrawn JP2013165712A (ja) 1999-12-23 2013-02-28 Il−17相同的ポリペプチドとその治療上の用途
JP2014138440A Pending JP2014239685A (ja) 1999-12-23 2014-07-04 Il−17相同的ポリペプチドとその治療上の用途
JP2014166220A Pending JP2015007091A (ja) 1999-12-23 2014-08-18 Il−17相同的ポリペプチドとその治療上の用途
JP2014243369A Withdrawn JP2015077137A (ja) 1999-12-23 2014-12-01 Il−17相同的ポリペプチドとその治療上の用途

Country Status (10)

Country Link
EP (1) EP1240325B1 (enExample)
JP (10) JP5070117B2 (enExample)
AT (5) ATE541931T1 (enExample)
AU (1) AU2590901A (enExample)
CA (1) CA2391374A1 (enExample)
CY (1) CY1112334T1 (enExample)
DK (1) DK1240325T3 (enExample)
ES (7) ES2388748T3 (enExample)
PT (4) PT1240325E (enExample)
WO (1) WO2001046420A2 (enExample)

Families Citing this family (43)

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US6562578B1 (en) 1999-01-11 2003-05-13 Schering Corporation IL-17-like cytokine binding compounds and antibodies
US7771719B1 (en) 2000-01-11 2010-08-10 Genentech, Inc. Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E
NZ508878A (en) 1998-05-15 2003-08-29 Genentech Inc IL-17B and IL-17Cactive variants of IL-17 which stimulates epithelial, endothelial and fibroblastic cells
JP2003525251A (ja) * 2000-02-29 2003-08-26 ザイモジェネティクス,インコーポレイティド シュワン細胞によるミエリンの産生を促進するための方法
US7718397B2 (en) 2000-03-21 2010-05-18 Genentech, Inc. Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof
DE60136921D1 (de) * 2000-04-18 2009-01-22 Schering Corp Medizinische Verwendung von IL-174 Agonisten und Antagonisten
MXPA02011617A (es) * 2000-05-24 2003-03-10 Schering Corp Proteinas de mamiferos receptoras, reactivosy metodos relacionados.
US20030096969A1 (en) 2000-06-02 2003-05-22 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2427824A1 (en) * 2000-07-26 2002-01-31 Zymogenetics, Inc. Human cytokine receptor
EP1529843A3 (en) * 2000-08-11 2005-06-08 Eli Lilly & Company Novel secreted proteins and their uses
AU2001296229A1 (en) * 2000-10-13 2002-04-29 Eli Lilly And Company Methods of using a human il-17-related polypeptide to treat disease
US20040171109A1 (en) * 2000-11-10 2004-09-02 Dominik Haudenschild IL-17 receptor-like protein, uses thereof, and modulation of catabolic activity of il-17 cytokines on bone and cartilage
US20070160576A1 (en) 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
AU2002351505B2 (en) * 2001-10-19 2008-04-03 Genentech, Inc. Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders
AU2003267096B9 (en) * 2002-09-11 2010-11-11 Genentech, Inc. Novel compositions and methods for the treatment of immune related diseases
WO2004047728A2 (en) * 2002-11-26 2004-06-10 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
WO2005051988A2 (en) * 2003-03-03 2005-06-09 Genentech, Inc. Compositions and methods for the treatment of systemic lupus erythematosis
EP1641822B1 (en) * 2003-07-08 2013-05-15 Genentech, Inc. Il-17 a/f heterologous polypeptides and therapeutic uses thereof
DK1983000T3 (en) 2003-11-21 2015-12-07 Ucb Biopharma Sprl A method for the treatment of multiple sclerosis by inhibiting IL-17 activity
US20050287593A1 (en) 2004-05-03 2005-12-29 Schering Corporation Use of cytokine expression to predict skin inflammation; methods of treatment
BRPI0510617A (pt) * 2004-05-03 2007-10-30 Schering Corp uso de expressão de il-17 para prever inflamação de pele; processos de tratamento
US7910540B2 (en) 2004-06-10 2011-03-22 Zymogenetics, Inc. Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation
EP1799248B1 (en) * 2004-09-21 2009-04-08 Merck Serono SA Use of il-17f for the treatment and/or prevention of neurologic diseases
JP2009505967A (ja) * 2005-08-04 2009-02-12 ザイモジェネティクス, インコーポレイテッド Il−17bを用いた創傷の処置方法
US20070249533A1 (en) 2005-09-28 2007-10-25 Levin Steven D Il-17a and il-17f antagonists and methods of using the same
DE602007006429D1 (de) 2006-02-10 2010-06-24 Zymogenetics Inc Lösliches il-17rcx4 und verfahren zu dessen anwendung bei entzündungen
EP2091968A2 (en) 2006-10-26 2009-08-26 Novo Nordisk A/S Il-21 variants
EP2089050A2 (en) * 2006-11-08 2009-08-19 Zymogenetics, Inc. Il- 17b for use in wound healing
US7790676B2 (en) 2007-03-28 2010-09-07 Zymogenetics, Inc. Soluble IL-17RA/RC fusion proteins
KR20170023209A (ko) 2008-05-05 2017-03-02 노비뮨 에스 에이 항-il-17a/il-17f 교차-반응성 항체 및 그의 사용 방법
US8790642B2 (en) 2008-08-29 2014-07-29 Genentech, Inc. Cross-reactive and bispecific anti-IL-17A/F antibodies
EP2406282A1 (en) 2009-03-11 2012-01-18 Novo Nordisk A/S Interleukin-21 variants having antagonistic binding to the il-21 receptor
AR075998A1 (es) 2009-04-01 2011-05-11 Genentech Inc Tratamiento de trastornos resistentes a insulina.composicion farmaceutica. uso. kit
GB0905972D0 (en) 2009-04-06 2009-05-20 Medical Res Council Antibodies against IL-17BR
PE20120815A1 (es) 2009-05-05 2012-07-08 Novimmune Sa Anticuerpos anti il-17f y metodos de uso de los mismos
WO2010142551A2 (en) * 2009-06-12 2010-12-16 Ablynx N.V. Single variable domain (vhh) antibodies to cytokines of the il-17 receptor family
JP2014506259A (ja) 2011-01-17 2014-03-13 ノヴォ ノルディスク アー/エス Il−21リガンド
UA117218C2 (uk) 2011-05-05 2018-07-10 Мерк Патент Гмбх Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
HUE037087T2 (hu) * 2011-10-19 2018-08-28 Morphosys Ag IL17C antagonistái gyulladásos rendellenességek kezelésére
JP6236948B2 (ja) * 2013-07-17 2017-11-29 東ソー株式会社 抗体精製用溶出液および当該溶出液を用いた抗体精製方法
KR20150050921A (ko) * 2013-11-01 2015-05-11 현대중공업 주식회사 폐열 회수용 연관식 보일러
CN107148283A (zh) 2014-10-31 2017-09-08 豪夫迈·罗氏有限公司 抗il‑17a和il‑17f交叉反应性抗体变体、包含其的组合物及其制备和使用方法
EP3250927B1 (en) 2015-01-28 2020-02-19 H. Hoffnabb-La Roche Ag Gene expression markers and treatment of multiple sclerosis

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