JP2006223304A5 - - Google Patents
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- Publication number
- JP2006223304A5 JP2006223304A5 JP2006024604A JP2006024604A JP2006223304A5 JP 2006223304 A5 JP2006223304 A5 JP 2006223304A5 JP 2006024604 A JP2006024604 A JP 2006024604A JP 2006024604 A JP2006024604 A JP 2006024604A JP 2006223304 A5 JP2006223304 A5 JP 2006223304A5
- Authority
- JP
- Japan
- Prior art keywords
- acid sequence
- amino acid
- polypeptide
- nucleic acid
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 16
- 108090000765 processed proteins & peptides Proteins 0.000 claims 16
- 102000004196 processed proteins & peptides Human genes 0.000 claims 16
- 125000003275 alpha amino acid group Chemical group 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 10
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 5
- 108091026890 Coding region Proteins 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 230000008878 coupling Effects 0.000 claims 3
- 238000010168 coupling process Methods 0.000 claims 3
- 238000005859 coupling reaction Methods 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 2
- 239000013068 control sample Substances 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 241000588724 Escherichia coli Species 0.000 claims 1
- 206010019695 Hepatic neoplasm Diseases 0.000 claims 1
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 108020005187 Oligonucleotide Probes Proteins 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 239000006143 cell culture medium Substances 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002751 oligonucleotide probe Substances 0.000 claims 1
- 238000005897 peptide coupling reaction Methods 0.000 claims 1
Applications Claiming Priority (22)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22989600P | 2000-09-01 | 2000-09-01 | |
| US23062100P | 2000-09-05 | 2000-09-05 | |
| US23514700P | 2000-09-22 | 2000-09-22 | |
| PCT/US2000/030873 WO2001040465A2 (en) | 1999-11-30 | 2000-11-10 | Compositions and methods for the treatment of immune related diseases |
| US26187801P | 2001-01-12 | 2001-01-12 | |
| US26215001P | 2001-01-16 | 2001-01-16 | |
| US26193901P | 2001-01-16 | 2001-01-16 | |
| US26191001P | 2001-01-16 | 2001-01-16 | |
| US26439501P | 2001-01-25 | 2001-01-25 | |
| US26642101P | 2001-02-02 | 2001-02-02 | |
| US26762301P | 2001-02-09 | 2001-02-09 | |
| PCT/US2001/006520 WO2001068848A2 (en) | 2000-03-01 | 2001-02-28 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US27439901P | 2001-03-09 | 2001-03-09 | |
| US28098201P | 2001-04-03 | 2001-04-03 | |
| US28219901P | 2001-04-04 | 2001-04-04 | |
| US28212901P | 2001-04-04 | 2001-04-04 | |
| US29058901P | 2001-05-09 | 2001-05-09 | |
| PCT/US2001/017092 WO2001092331A2 (en) | 2000-05-30 | 2001-05-25 | Compositions and methods for the treatment of immune related diseases |
| PCT/US2001/017800 WO2001093983A1 (en) | 2000-06-02 | 2001-06-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2001/019692 WO2002000690A2 (en) | 2000-06-23 | 2001-06-20 | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| PCT/US2001/021066 WO2002008288A2 (en) | 2000-07-20 | 2001-06-29 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2001/021735 WO2002008284A2 (en) | 2000-07-20 | 2001-07-09 | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002529483A Division JP4451059B2 (ja) | 2000-09-01 | 2001-08-29 | 分泌及び膜貫通ポリペプチドとそれをコードする核酸 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006223304A JP2006223304A (ja) | 2006-08-31 |
| JP2006223304A5 true JP2006223304A5 (enExample) | 2008-10-09 |
Family
ID=27585542
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002529483A Expired - Lifetime JP4451059B2 (ja) | 2000-09-01 | 2001-08-29 | 分泌及び膜貫通ポリペプチドとそれをコードする核酸 |
| JP2006024604A Pending JP2006223304A (ja) | 2000-09-01 | 2006-02-01 | 分泌及び膜貫通ポリペプチドとそれをコードする核酸 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002529483A Expired - Lifetime JP4451059B2 (ja) | 2000-09-01 | 2001-08-29 | 分泌及び膜貫通ポリペプチドとそれをコードする核酸 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1341814A2 (enExample) |
| JP (2) | JP4451059B2 (enExample) |
| AU (2) | AU2002216610A1 (enExample) |
| CA (2) | CA2421056A1 (enExample) |
| WO (1) | WO2002024888A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6395511B1 (en) | 1998-11-27 | 2002-05-28 | Darwin Discovery, Ltd. | Nucleic acids encoding a novel family of TGF-β binding proteins from humans |
| US20040009535A1 (en) | 1998-11-27 | 2004-01-15 | Celltech R&D, Inc. | Compositions and methods for increasing bone mineralization |
| EP1686134A3 (en) * | 1999-12-01 | 2006-08-09 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WO2001098491A2 (en) * | 2000-06-19 | 2001-12-27 | F. Hoffmann-La Roche Ag | Osteolevin gene polymorphisms |
| US7268223B2 (en) | 2000-09-22 | 2007-09-11 | Wyeth | Isolated nucleic acid molecules which encode a soluble IL-TIF receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof |
| US7094570B2 (en) | 2003-03-11 | 2006-08-22 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules which encode a soluble IL-TIF/IL-22 receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof |
| JP2004533811A (ja) | 2001-01-12 | 2004-11-11 | ジェネティクス インスティテュート，エルエルシー | ２型サイトカインレセプターおよび２型サイトカインレセプターをコードする核酸 |
| AU2002325333B2 (en) * | 2001-07-19 | 2008-04-03 | Innate Pharma | NTB-A, a surface molecule involved in natural killer cells activity |
| AU2003276430A1 (en) | 2002-06-14 | 2003-12-31 | Stowers Institute For Medical Research | Wise/sost nucleic acid sequences and amino acid sequences |
| US7893218B2 (en) | 2003-06-16 | 2011-02-22 | Stowers Institute For Medical Research | Antibodies that specifically bind SOST peptides |
| US7585501B2 (en) | 2002-06-14 | 2009-09-08 | Stowers Institute For Medical Research | Compositions and methods for treating kidney disease |
| FR2844713A1 (fr) * | 2002-09-25 | 2004-03-26 | Exonhit Therapeutics Sa | Nouvelle cible de l'angiogenese et utilisations |
| AU2003269557A1 (en) * | 2002-10-18 | 2004-05-04 | Lg Life Sciences Ltd. | Gene families associated with cancers |
| NZ544618A (en) | 2003-06-16 | 2009-02-28 | Celltech R & D Inc | Antibodies specific for sclerostin and methods for increasing bone mineralization |
| US7592429B2 (en) | 2005-05-03 | 2009-09-22 | Ucb Sa | Sclerostin-binding antibody |
| US8003108B2 (en) | 2005-05-03 | 2011-08-23 | Amgen Inc. | Sclerostin epitopes |
| CL2008002775A1 (es) | 2007-09-17 | 2008-11-07 | Amgen Inc | Uso de un agente de unión a esclerostina para inhibir la resorción ósea. |
| US8921058B2 (en) | 2009-10-26 | 2014-12-30 | Externautics Spa | Prostate tumor markers and methods of use thereof |
| US10288617B2 (en) | 2009-10-26 | 2019-05-14 | Externautics Spa | Ovary tumor markers and methods of use thereof |
| EP2383578A1 (en) * | 2010-04-30 | 2011-11-02 | Externautics S.p.A. | Tumor marker and methods of use thereof |
| SMT202000095T1 (it) | 2010-05-14 | 2020-03-13 | Amgen Inc | Formulazioni di anticorpi anti-sclerostina ad alta concentrazione |
| JP2014509588A (ja) | 2011-03-01 | 2014-04-21 | アムジエン・インコーポレーテツド | 二特異性結合剤 |
| WO2012135035A1 (en) | 2011-03-25 | 2012-10-04 | Amgen Inc. | Anti - sclerostin antibody crystals and formulations thereof |
| SI2739311T1 (en) | 2011-08-04 | 2018-07-31 | Amgen Inc. | Method for the treatment of bone defect defects |
| ES2813524T3 (es) | 2011-12-28 | 2021-03-24 | Amgen Inc | Método para tratar la pérdida de hueso alveolar mediante el uso de anticuerpos antiesclerostina |
| WO2014006100A1 (en) | 2012-07-05 | 2014-01-09 | Ucb Pharma S.A. | Treatment for bone diseases |
| UY35148A (es) | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
| CN107880126B (zh) | 2012-12-21 | 2021-03-30 | 西雅图基因公司 | 抗ntb-a抗体及相关组合物和方法 |
| MA41142A (fr) | 2014-12-12 | 2017-10-17 | Amgen Inc | Anticorps anti-sclérostine et utilisation de ceux-ci pour traiter des affections osseuses en tant qu'élements du protocole de traitement |
| GB201604124D0 (en) | 2016-03-10 | 2016-04-27 | Ucb Biopharma Sprl | Pharmaceutical formulation |
| CN112166120B (zh) | 2018-03-30 | 2024-09-10 | 安姆根有限公司 | C末端抗体变体 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5707829A (en) * | 1995-08-11 | 1998-01-13 | Genetics Institute, Inc. | DNA sequences and secreted proteins encoded thereby |
| US5824504A (en) * | 1996-09-26 | 1998-10-20 | Elshourbagy; Nabil A. | Human 7-transmembrane receptor and DNA |
| CA2283299A1 (en) * | 1997-03-07 | 1998-09-11 | Human Genome Sciences, Inc. | 186 human secreted proteins |
| EP0998490A2 (en) * | 1997-03-25 | 2000-05-10 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| DE19817557A1 (de) * | 1998-04-09 | 1999-10-21 | Metagen Gesellschaft Fuer Genomforschung Mbh | Menschliche Nukleinsäuresequenzen aus Ovartumorgewebe |
| IL139686A0 (en) * | 1998-06-02 | 2002-02-10 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| AU3395900A (en) * | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| JP2004522402A (ja) * | 1999-06-02 | 2004-07-29 | ジェネンテック・インコーポレーテッド | 同一のものをコードする分泌及び膜貫通ポリペプチドと核酸 |
-
2001
- 2001-08-29 CA CA002421056A patent/CA2421056A1/en not_active Abandoned
- 2001-08-29 JP JP2002529483A patent/JP4451059B2/ja not_active Expired - Lifetime
- 2001-08-29 EP EP01985272A patent/EP1341814A2/en not_active Ceased
- 2001-08-29 AU AU2002216610A patent/AU2002216610A1/en not_active Abandoned
- 2001-08-29 WO PCT/US2001/027099 patent/WO2002024888A2/en not_active Ceased
- 2001-08-29 CA CA002632702A patent/CA2632702A1/en not_active Abandoned
- 2001-09-19 AU AU1661002A patent/AU1661002A/xx active Pending
-
2006
- 2006-02-01 JP JP2006024604A patent/JP2006223304A/ja active Pending
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