JP2006025793A5 - - Google Patents
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- Publication number
- JP2006025793A5 JP2006025793A5 JP2005229454A JP2005229454A JP2006025793A5 JP 2006025793 A5 JP2006025793 A5 JP 2006025793A5 JP 2005229454 A JP2005229454 A JP 2005229454A JP 2005229454 A JP2005229454 A JP 2005229454A JP 2006025793 A5 JP2006025793 A5 JP 2006025793A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- polypeptide
- amino acid
- cancer
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 claims 12
- 229920001184 polypeptide Polymers 0.000 claims 11
- 102000004196 processed proteins & peptides Human genes 0.000 claims 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 125000003275 alpha amino acid group Chemical group 0.000 claims 9
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 230000002401 inhibitory effect Effects 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 7
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 230000004565 tumor cell growth Effects 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 210000004881 tumor cell Anatomy 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 1
- 208000035561 Leukaemic infiltration brain Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 206010038389 Renal cancer Diseases 0.000 claims 1
- 239000006143 cell culture medium Substances 0.000 claims 1
- 201000007455 central nervous system cancer Diseases 0.000 claims 1
- 201000010039 central nervous system leukemia Diseases 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000012010 growth Effects 0.000 claims 1
- 230000009036 growth inhibition Effects 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 201000010982 kidney cancer Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 210000005170 neoplastic cell Anatomy 0.000 claims 1
- 230000009826 neoplastic cell growth Effects 0.000 claims 1
- 208000013755 primary melanoma of the central nervous system Diseases 0.000 claims 1
- 230000004614 tumor growth Effects 0.000 claims 1
- 241000701447 unidentified baculovirus Species 0.000 claims 1
- 210000005253 yeast cell Anatomy 0.000 claims 1
Applications Claiming Priority (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1999/012252 WO1999063088A2 (en) | 1998-06-02 | 1999-06-02 | Membrane-bound proteins and nucleic acids encoding the same |
| US14065099P | 1999-06-22 | 1999-06-22 | |
| US14103799P | 1999-06-23 | 1999-06-23 | |
| US14475899P | 1999-07-20 | 1999-07-20 | |
| PCT/US1999/020111 WO2000012708A2 (en) | 1998-09-01 | 1999-09-01 | Further pro polypeptides and sequences thereof |
| PCT/US1999/020594 WO2000015666A2 (en) | 1998-09-10 | 1999-09-08 | Compositions and methods for the treatment of tumors |
| US16250699P | 1999-10-29 | 1999-10-29 | |
| PCT/US1999/028313 WO2000032221A2 (en) | 1998-12-01 | 1999-11-30 | Promotion or inhibition of angiogenesis and cardiovascularization |
| PCT/US1999/028634 WO2000036102A2 (en) | 1998-12-16 | 1999-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US1999/028551 WO2000053750A1 (en) | 1999-03-08 | 1999-12-02 | Compositions and methods for the treatment of tumors |
| US17026299P | 1999-12-09 | 1999-12-09 | |
| PCT/US1999/030095 WO2000037640A2 (en) | 1998-12-22 | 1999-12-16 | Compositions and methods for the treatment of tumor |
| PCT/US1999/030999 WO2001005836A1 (en) | 1999-07-20 | 1999-12-20 | Polypeptidic compositions and methods for the treatment of tumors |
| PCT/US2000/000376 WO2000053755A2 (en) | 1999-03-08 | 2000-01-06 | Compositions and methods for the treatment of tumor |
| PCT/US2000/003565 WO2001053486A1 (en) | 1999-03-08 | 2000-02-11 | Compositions and methods for the treatment of tumor |
| PCT/US2000/004342 WO2000078961A1 (en) | 1999-06-23 | 2000-02-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2000/004341 WO2000053756A2 (en) | 1999-03-08 | 2000-02-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2000/005841 WO2000053758A2 (en) | 1999-03-08 | 2000-03-02 | Compositions and methods for the treatment of immune related diseases |
| US18720200P | 2000-03-03 | 2000-03-03 | |
| PCT/US2000/006319 WO2000053760A2 (en) | 1999-03-12 | 2000-03-10 | Method of preventing the death of retinal neurons and treating ocular diseases |
| PCT/US2000/006884 WO2001005972A1 (en) | 1999-07-20 | 2000-03-15 | Compositions and methods for the treatment of immune related diseases |
| PCT/US2000/008439 WO2000073454A1 (en) | 1999-06-02 | 2000-03-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2000/013705 WO2000073445A2 (en) | 1999-06-02 | 2000-05-17 | Interleukin-1-receptor associated kinase-3 (irak3) |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001500672A Division JP2003524406A (ja) | 1999-06-02 | 2000-05-30 | 腫瘍細胞成長阻害のための組成物及び方法 |
Related Child Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006225770A Division JP4072181B2 (ja) | 1999-06-02 | 2006-08-22 | 腫瘍細胞成長阻害のための組成物及び方法 |
| JP2006225772A Division JP2007029098A (ja) | 1999-06-02 | 2006-08-22 | 腫瘍細胞成長阻害のための組成物及び方法 |
| JP2006225771A Division JP4074645B2 (ja) | 1999-06-02 | 2006-08-22 | 腫瘍細胞成長阻害のための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006025793A JP2006025793A (ja) | 2006-02-02 |
| JP2006025793A5 true JP2006025793A5 (enExample) | 2007-07-12 |
| JP4145314B2 JP4145314B2 (ja) | 2008-09-03 |
Family
ID=40532223
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005229454A Expired - Lifetime JP4145314B2 (ja) | 1999-06-02 | 2005-08-08 | 腫瘍細胞成長阻害のための組成物及び方法 |
| JP2006225770A Expired - Lifetime JP4072181B2 (ja) | 1999-06-02 | 2006-08-22 | 腫瘍細胞成長阻害のための組成物及び方法 |
| JP2006225772A Pending JP2007029098A (ja) | 1999-06-02 | 2006-08-22 | 腫瘍細胞成長阻害のための組成物及び方法 |
| JP2006225771A Expired - Lifetime JP4074645B2 (ja) | 1999-06-02 | 2006-08-22 | 腫瘍細胞成長阻害のための組成物及び方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006225770A Expired - Lifetime JP4072181B2 (ja) | 1999-06-02 | 2006-08-22 | 腫瘍細胞成長阻害のための組成物及び方法 |
| JP2006225772A Pending JP2007029098A (ja) | 1999-06-02 | 2006-08-22 | 腫瘍細胞成長阻害のための組成物及び方法 |
| JP2006225771A Expired - Lifetime JP4074645B2 (ja) | 1999-06-02 | 2006-08-22 | 腫瘍細胞成長阻害のための組成物及び方法 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1185648B1 (enExample) |
| JP (4) | JP4145314B2 (enExample) |
| AT (1) | ATE357518T1 (enExample) |
| CA (1) | CA2373915A1 (enExample) |
| DK (1) | DK1185648T3 (enExample) |
| ES (1) | ES2287020T3 (enExample) |
| PT (1) | PT1185648E (enExample) |
| WO (1) | WO2000073348A2 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001016319A2 (en) * | 1999-08-31 | 2001-03-08 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| US20020192752A1 (en) | 1998-09-09 | 2002-12-19 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| US6623923B1 (en) | 1998-12-23 | 2003-09-23 | Corixa Corporation | Compounds for immunotherapy and diagnosis of colon cancer and methods for their use |
| US20020055467A1 (en) * | 1998-07-06 | 2002-05-09 | Johansen Teit E. | Novel neurotrophic factors |
| US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
| US20070014787A1 (en) | 1998-07-15 | 2007-01-18 | Human Genome Sciences, Inc. | 71 human secreted proteins |
| JP2002533082A (ja) * | 1998-12-23 | 2002-10-08 | コリクサ コーポレイション | 結腸癌の免疫療法および診断のための化合物およびそれらの使用のための方法 |
| DK1607402T3 (da) * | 1999-03-08 | 2007-04-16 | Genentech Inc | Sammensætninger og fremgangsmåder til tumorbehandling |
| US7282562B2 (en) | 1999-08-31 | 2007-10-16 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| WO2001023553A2 (en) * | 1999-09-29 | 2001-04-05 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Metastasis-associated antigen c4.4a |
| EP1242598A2 (en) * | 1999-12-30 | 2002-09-25 | Corixa Corporation | Compounds for immunotherapy and diagnosis of colon cancer and methods for their use |
| AU2001255168A1 (en) * | 2000-03-03 | 2001-09-17 | Genentech Inc. | Compositions and methods for the treatment of immune related diseases |
| WO2001072958A2 (en) * | 2000-03-28 | 2001-10-04 | Beth Israel Deaconess Medical Center | Bladder cancer-specific peptides for diagnosis and therapy |
| US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
| US7276580B2 (en) | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
| US6734289B2 (en) | 2001-03-29 | 2004-05-11 | The University Of Chicago | Gastrokines and derived peptides including inhibitors |
| US7629317B2 (en) | 2001-03-29 | 2009-12-08 | The University Of Chicago | Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors |
| EP1438427B1 (en) | 2001-09-14 | 2016-04-20 | Clinical Genomics Pty. Ltd | Nucleic acid markers for use in determining predisposition to neoplasm and/or adenoma |
| WO2003053334A2 (en) * | 2001-12-19 | 2003-07-03 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| NZ535925A (en) * | 2002-04-16 | 2008-06-30 | Genentech Inc | An isolated antibody that binds to a particular polypeptide |
| AU2003253677A1 (en) * | 2002-06-11 | 2003-12-22 | Avalon Pharmaceuticals, Inc. | Cancer-linked gene as target for chemotherapy |
| AU2003267096B9 (en) * | 2002-09-11 | 2010-11-11 | Genentech, Inc. | Novel compositions and methods for the treatment of immune related diseases |
| DE10254601A1 (de) | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| US20050187175A1 (en) * | 2003-09-30 | 2005-08-25 | Elly Nedivi | Methods and compositions for CPG15-2 |
| DE102004024617A1 (de) | 2004-05-18 | 2005-12-29 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| ATE472333T1 (de) | 2004-08-19 | 2010-07-15 | Biogen Idec Inc | Rückfaltung von proteinen der transforming-growth-factor-beta-familie |
| US8017576B2 (en) | 2005-05-10 | 2011-09-13 | The University Of Chicago | Methods and compositions to treat mucositis |
| EP1790664A1 (en) | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoclonal antibodies against claudin-18 for treatment of cancer |
| WO2007095113A2 (en) | 2006-02-10 | 2007-08-23 | Massachusetts Institute Of Technology | Cpg15 and cpg15-2 compounds and inhibitors as insulin receptor and insulin-like growth factor receptor agonists and antagonists |
| TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
| AU2008247637B2 (en) | 2007-05-01 | 2013-12-05 | Biogen Ma Inc. | Compositions and methods for increasing vascularization |
| HRP20231525T1 (hr) | 2009-02-20 | 2024-03-15 | Astellas Pharma Inc. | Postupci i pripravci za dijagnozu i liječenje raka |
| HUE035516T2 (en) | 2009-11-11 | 2018-05-28 | Ganymed Pharmaceuticals Gmbh | Antibodies specific to Claulin-6 (CLDN6) |
| EP2404936A1 (en) | 2010-07-06 | 2012-01-11 | Ganymed Pharmaceuticals AG | Cancer therapy using CLDN6 target-directed antibodies in vivo |
| JP6276176B2 (ja) | 2011-05-13 | 2018-02-07 | ガニメド ファーマシューティカルズ ゲーエムベーハー | 癌の治療のための抗体 |
| JP5891561B2 (ja) * | 2011-06-03 | 2016-03-23 | 学校法人自治医科大学 | ミトコンドリア膜タンパク質群およびそれらをコードする遺伝子群 |
| WO2013167153A1 (en) | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis |
| WO2015014376A1 (en) | 2013-07-31 | 2015-02-05 | Biontech Ag | Diagnosis and therapy of cancer involving cancer stem cells |
| CN115197301B (zh) * | 2022-06-10 | 2024-07-16 | 北京师范大学 | 用于胞内钙信号检测及相关药物筛选的钙指示工具及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ226799A (en) * | 1987-11-06 | 1991-08-27 | Oncogen | Breast cancer inhibitory factor and method for inhibiting proliferation of neoplastic cells and compositions therefor |
| US5814307A (en) * | 1989-04-10 | 1998-09-29 | Bristol-Myers Squibb Company | Method for regulating cell growth, leukocyte differentiation and tumor cell growth using Oncostatin M to stimulate synthesis of IL-6 |
| US5416192A (en) * | 1990-04-03 | 1995-05-16 | Bristol-Myers Squibb Company | Epithelins: novel cysteine-rich growth modulating proteins |
| AU4694696A (en) * | 1996-01-04 | 1997-08-01 | Human Genome Sciences, Inc. | Transforming growth factor alpha hiii |
| AU9312198A (en) * | 1997-09-17 | 1999-04-05 | Genentech Inc. | Genes amplified in tumours, antibodies against the proteins encoded thereby, andtheir use in diagnosis and treatment of cancer |
| EP1021532A2 (en) * | 1997-10-08 | 2000-07-26 | Sagami Chemical Research Center | HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS |
| EP1109833A2 (en) * | 1998-09-10 | 2001-06-27 | Genentech, Inc. | Compositions and methods for the treatment of tumors |
-
2000
- 2000-05-30 CA CA002373915A patent/CA2373915A1/en not_active Abandoned
- 2000-05-30 EP EP00941164A patent/EP1185648B1/en not_active Expired - Lifetime
- 2000-05-30 ES ES00941164T patent/ES2287020T3/es not_active Expired - Lifetime
- 2000-05-30 PT PT00941164T patent/PT1185648E/pt unknown
- 2000-05-30 WO PCT/US2000/014941 patent/WO2000073348A2/en not_active Ceased
- 2000-05-30 DK DK00941164T patent/DK1185648T3/da active
- 2000-05-30 AT AT00941164T patent/ATE357518T1/de not_active IP Right Cessation
-
2005
- 2005-08-08 JP JP2005229454A patent/JP4145314B2/ja not_active Expired - Lifetime
-
2006
- 2006-08-22 JP JP2006225770A patent/JP4072181B2/ja not_active Expired - Lifetime
- 2006-08-22 JP JP2006225772A patent/JP2007029098A/ja active Pending
- 2006-08-22 JP JP2006225771A patent/JP4074645B2/ja not_active Expired - Lifetime
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