JP2003527078A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2003527078A5 JP2003527078A5 JP2000614364A JP2000614364A JP2003527078A5 JP 2003527078 A5 JP2003527078 A5 JP 2003527078A5 JP 2000614364 A JP2000614364 A JP 2000614364A JP 2000614364 A JP2000614364 A JP 2000614364A JP 2003527078 A5 JP2003527078 A5 JP 2003527078A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- polynucleotide
- seq
- amino acid
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091033319 polynucleotide Proteins 0.000 description 27
- 239000002157 polynucleotide Substances 0.000 description 27
- 102000040430 polynucleotide Human genes 0.000 description 27
- 102000004169 proteins and genes Human genes 0.000 description 27
- 108090000623 proteins and genes Proteins 0.000 description 27
- 239000002773 nucleotide Substances 0.000 description 19
- 125000003729 nucleotide group Chemical group 0.000 description 19
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 15
- 125000003275 alpha amino acid group Chemical group 0.000 description 14
- 150000001413 amino acids Chemical class 0.000 description 7
- 239000002299 complementary DNA Substances 0.000 description 7
- 239000012634 fragment Substances 0.000 description 7
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 108091026890 Coding region Proteins 0.000 description 3
- 108060003951 Immunoglobulin Proteins 0.000 description 2
- 108020001507 fusion proteins Proteins 0.000 description 2
- 102000037865 fusion proteins Human genes 0.000 description 2
- 102000018358 immunoglobulin Human genes 0.000 description 2
- 239000003937 drug carrier Substances 0.000 description 1
- 210000004962 mammalian cell Anatomy 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13147399P | 1999-04-28 | 1999-04-28 | |
| US60/131,473 | 1999-04-28 | ||
| PCT/US2000/011479 WO2000065027A2 (en) | 1999-04-28 | 2000-04-28 | Human gil-19/ae289 proteins and polynucleotides encoding same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011034204A Division JP2011160804A (ja) | 1999-04-28 | 2011-02-21 | ヒトｇｉｌ−１９／ａｅ２８９タンパク質、及び、同タンパク質をコードするポリヌクレオチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003527078A JP2003527078A (ja) | 2003-09-16 |
| JP2003527078A5 true JP2003527078A5 (enExample) | 2007-10-18 |
| JP4828703B2 JP4828703B2 (ja) | 2011-11-30 |
Family
ID=22449618
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000614364A Expired - Fee Related JP4828703B2 (ja) | 1999-04-28 | 2000-04-28 | ヒトｇｉｌ−１９／ａｅ２８９タンパク質、及び、同タンパク質をコードするポリヌクレオチド |
| JP2011034204A Pending JP2011160804A (ja) | 1999-04-28 | 2011-02-21 | ヒトｇｉｌ−１９／ａｅ２８９タンパク質、及び、同タンパク質をコードするポリヌクレオチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011034204A Pending JP2011160804A (ja) | 1999-04-28 | 2011-02-21 | ヒトｇｉｌ−１９／ａｅ２８９タンパク質、及び、同タンパク質をコードするポリヌクレオチド |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP2357193B1 (enExample) |
| JP (2) | JP4828703B2 (enExample) |
| AT (1) | ATE377077T1 (enExample) |
| BR (1) | BR0010097A (enExample) |
| CA (1) | CA2367965C (enExample) |
| CY (1) | CY1107138T1 (enExample) |
| DE (1) | DE60036937T2 (enExample) |
| DK (1) | DK1177312T3 (enExample) |
| ES (2) | ES2295026T3 (enExample) |
| MX (1) | MXPA01010883A (enExample) |
| NZ (1) | NZ515678A (enExample) |
| PT (1) | PT1177312E (enExample) |
| WO (1) | WO2000065027A2 (enExample) |
| ZA (1) | ZA200109270B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002016611A2 (en) * | 2000-08-24 | 2002-02-28 | Genentech, Inc. | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
| US6551799B2 (en) | 1999-12-07 | 2003-04-22 | Genentech, Inc. | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
| US6274710B1 (en) | 1998-10-26 | 2001-08-14 | Ludwig Institute For Cancer Research | Antibodies which specifically bind T Cell inducible factors (TIFs) |
| US6331613B1 (en) * | 1998-10-26 | 2001-12-18 | Ludwig Institue For Cancer Research | Isolated nucleic acid molecules which encode T cell inducible factors (TIFS), the proteins encoded, and uses thereof |
| WO2000065027A2 (en) * | 1999-04-28 | 2000-11-02 | Genetics Institute, Inc. | Human gil-19/ae289 proteins and polynucleotides encoding same |
| US6897292B2 (en) | 1999-12-03 | 2005-05-24 | Zymogenetics, Inc. | Human cytokine receptor |
| US7226591B2 (en) | 2000-05-22 | 2007-06-05 | Genentech, Inc. | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
| ATE459716T1 (de) * | 1999-12-23 | 2010-03-15 | Zymogenetics Inc | Zytokin zcyt018 |
| US20030170823A1 (en) | 1999-12-23 | 2003-09-11 | Presnell Scott R. | Novel cytokine ZCYTO18 |
| AU7303301A (en) * | 2000-07-27 | 2002-02-13 | Ludwig Inst Cancer Res | Isolated nucleic acid molecules which encode t cell inducible factors, or interleukin-21, the proteins encoded, and uses thereof |
| WO2002012345A2 (en) | 2000-08-08 | 2002-02-14 | Zymogenetics, Inc. | Soluble zcytor 11 cytokine receptors |
| US7094570B2 (en) | 2003-03-11 | 2006-08-22 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules which encode a soluble IL-TIF/IL-22 receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof |
| US7268223B2 (en) | 2000-09-22 | 2007-09-11 | Wyeth | Isolated nucleic acid molecules which encode a soluble IL-TIF receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof |
| NZ527396A (en) * | 2001-02-23 | 2007-12-21 | Genetics Inst Llc | Antibodies and fragments thereof for the binding of IL-22 and use therefore for treating inflammatory disorders |
| WO2002077174A2 (en) | 2001-03-27 | 2002-10-03 | Zymogenetics, Inc. | Human cytokine receptor |
| US7033787B2 (en) | 2001-12-21 | 2006-04-25 | Ludwig Institute For Cancer Research | Isolated cytokine receptor LICR-2 |
| JP4504023B2 (ja) | 2002-03-22 | 2010-07-14 | ザイモジェネティクス インコーポレーティッド | 抗ｉｌ−ｔｉｆ抗体および炎症において使用する方法 |
| MXPA05010134A (es) | 2003-03-24 | 2005-11-16 | Zymogenetics Inc | Anticuerpos anti-il-20, metodos y moleculas de enlace que se usan en la inflamacion. |
| US7261882B2 (en) | 2003-06-23 | 2007-08-28 | Reagents Of The University Of Colorado | Methods for treating neuropathic pain by administering IL-10 polypeptides |
| US7537761B2 (en) | 2004-10-22 | 2009-05-26 | Zymogenetics, Inc. | Anti-IL-22RA antibodies and binding partners and methods of using in inflammation |
| LT2816118T (lt) | 2005-05-31 | 2018-12-10 | The Regents Of The University Of Colorado, A Body Corporate | Genų pristatymo būdai |
| EA035645B1 (ru) | 2013-03-15 | 2020-07-21 | Дженентек, Инк. | ПОЛИПЕПТИДЫ IL-22, ХИМЕРНЫЕ БЕЛКИ IL-22 Fc И ИХ ПРИМЕНЕНИЕ |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4518584A (en) | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
| US5169939A (en) | 1985-05-21 | 1992-12-08 | Massachusetts Institute Of Technology & Pres. & Fellows Of Harvard College | Chimeric antibodies |
| US4798885A (en) | 1986-02-07 | 1989-01-17 | Genentech, Inc. | Compositions of hormonally active human and porcine inhibin containing an α chain and 62 chain |
| US4737323A (en) | 1986-02-13 | 1988-04-12 | Liposome Technology, Inc. | Liposome extrusion method |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5576184A (en) | 1988-09-06 | 1996-11-19 | Xoma Corporation | Production of chimeric mouse-human antibodies with specificity to human tumor antigens |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| US5126323A (en) | 1989-11-16 | 1992-06-30 | Genetics Institute, Inc. | Homogeneous purified k-fgf and compositions containing the same |
| US5614396A (en) | 1990-06-14 | 1997-03-25 | Baylor College Of Medicine | Methods for the genetic modification of endogenous genes in animal cells by homologous recombination |
| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5194594A (en) | 1990-09-07 | 1993-03-16 | Techniclone, Inc. | Modified antibodies |
| NZ245015A (en) | 1991-11-05 | 1995-12-21 | Transkaryotic Therapies Inc | Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production |
| US5536637A (en) | 1993-04-07 | 1996-07-16 | Genetics Institute, Inc. | Method of screening for cDNA encoding novel secreted mammalian proteins in yeast |
| US6664107B1 (en) | 1993-05-26 | 2003-12-16 | Ontario Cancer Institute, University Health Network | CD45 disrupted nucleic acid |
| DK0716610T3 (da) | 1993-08-26 | 2006-09-04 | Genetics Inst Llc | Humane knogle-morfogenetiske proteiner til anvendelse ved neural regenerering |
| DK0733109T3 (da) | 1993-12-07 | 2006-07-03 | Genetics Inst Llc | BMP-12, BMP-13 og seneinducerende præparater dermed |
| US5679523A (en) | 1995-11-16 | 1997-10-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method for concurrent disruption of expression of multiple alleles of mammalian genes |
| US6331613B1 (en) * | 1998-10-26 | 2001-12-18 | Ludwig Institue For Cancer Research | Isolated nucleic acid molecules which encode T cell inducible factors (TIFS), the proteins encoded, and uses thereof |
| US6274710B1 (en) * | 1998-10-26 | 2001-08-14 | Ludwig Institute For Cancer Research | Antibodies which specifically bind T Cell inducible factors (TIFs) |
| WO2000065027A2 (en) * | 1999-04-28 | 2000-11-02 | Genetics Institute, Inc. | Human gil-19/ae289 proteins and polynucleotides encoding same |
| WO2000073457A1 (en) * | 1999-05-27 | 2000-12-07 | Schering-Corporation | Mammalian interleukin-10 homologs: il-d110 and il-d210 |
| US20020187512A1 (en) * | 2001-09-10 | 2002-12-12 | Nagem Ronaldo Alves Pinto | Crystal structure of human interleukin-22 |
| TWI417301B (zh) * | 2006-02-21 | 2013-12-01 | Wyeth Corp | 對抗人類介白素-２２（ｉｌ-２２）之抗體及其用途 |
-
2000
- 2000-04-28 WO PCT/US2000/011479 patent/WO2000065027A2/en not_active Ceased
- 2000-04-28 EP EP10185792.8A patent/EP2357193B1/en not_active Expired - Lifetime
- 2000-04-28 CA CA2367965A patent/CA2367965C/en not_active Expired - Lifetime
- 2000-04-28 PT PT00928535T patent/PT1177312E/pt unknown
- 2000-04-28 DK DK00928535T patent/DK1177312T3/da active
- 2000-04-28 ES ES00928535T patent/ES2295026T3/es not_active Expired - Lifetime
- 2000-04-28 JP JP2000614364A patent/JP4828703B2/ja not_active Expired - Fee Related
- 2000-04-28 MX MXPA01010883A patent/MXPA01010883A/es active IP Right Grant
- 2000-04-28 DE DE60036937T patent/DE60036937T2/de not_active Expired - Lifetime
- 2000-04-28 NZ NZ515678A patent/NZ515678A/xx not_active IP Right Cessation
- 2000-04-28 BR BR0010097-8A patent/BR0010097A/pt not_active IP Right Cessation
- 2000-04-28 EP EP00928535A patent/EP1177312B1/en not_active Expired - Lifetime
- 2000-04-28 ES ES07119666T patent/ES2530857T3/es not_active Expired - Lifetime
- 2000-04-28 AT AT00928535T patent/ATE377077T1/de active
-
2001
- 2001-11-09 ZA ZA200109270A patent/ZA200109270B/xx unknown
-
2008
- 2008-01-14 CY CY20081100050T patent/CY1107138T1/el unknown
-
2011
- 2011-02-21 JP JP2011034204A patent/JP2011160804A/ja active Pending