JPH11170A5 - - Google Patents
Info
- Publication number
- JPH11170A5 JPH11170A5 JP1997057503A JP5750397A JPH11170A5 JP H11170 A5 JPH11170 A5 JP H11170A5 JP 1997057503 A JP1997057503 A JP 1997057503A JP 5750397 A JP5750397 A JP 5750397A JP H11170 A5 JPH11170 A5 JP H11170A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- polypeptide
- acid sequence
- seq
- nucleotide sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1328596P | 1996-03-12 | 1996-03-12 | |
| US2871196P | 1996-10-17 | 1996-10-17 | |
| US3734197P | 1997-02-06 | 1997-02-06 | |
| US60/013285 | 1997-02-06 | ||
| US60/028711 | 1997-02-06 | ||
| US60/037341 | 1997-02-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11170A JPH11170A (ja) | 1999-01-06 |
| JPH11170A5 true JPH11170A5 (enExample) | 2005-02-10 |
Family
ID=27359824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9057503A Pending JPH11170A (ja) | 1996-03-12 | 1997-03-12 | デスドメイン含有受容体 |
Country Status (3)
| Country | Link |
|---|---|
| US (3) | US6153402A (enExample) |
| JP (1) | JPH11170A (enExample) |
| WO (1) | WO1997033904A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030198640A1 (en) * | 1994-11-07 | 2003-10-23 | Human Genome Sciences, Inc. | Methods and compositions for treating inflammatory bowel diseases relating to human tumor necrosis factor-gamma-beta |
| US7597886B2 (en) | 1994-11-07 | 2009-10-06 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
| US7429646B1 (en) | 1995-06-05 | 2008-09-30 | Human Genome Sciences, Inc. | Antibodies to human tumor necrosis factor receptor-like 2 |
| US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
| US6713061B1 (en) | 1996-03-12 | 2004-03-30 | Human Genome Sciences, Inc. | Death domain containing receptors |
| WO1997033904A1 (en) | 1996-03-12 | 1997-09-18 | Human Genome Sciences, Inc. | Death domain containing receptors |
| US7964190B2 (en) | 1996-03-22 | 2011-06-21 | Human Genome Sciences, Inc. | Methods and compositions for decreasing T-cell activity |
| US6635743B1 (en) | 1996-03-22 | 2003-10-21 | Human Genome Sciences, Inc. | Apoptosis inducing molecule II and methods of use |
| JP2000507829A (ja) * | 1996-04-01 | 2000-06-27 | ジェネンテック インコーポレーテッド | Ａｐｏ―２ｌｉおよびａｐｏ―３アポトーシスポリペプチド |
| US20020165157A1 (en) * | 1996-04-01 | 2002-11-07 | Genentech, Inc. | Apo-2LI and Apo-3 polypeptides |
| US6462176B1 (en) * | 1996-09-23 | 2002-10-08 | Genentech, Inc. | Apo-3 polypeptide |
| AU718474B2 (en) * | 1996-10-04 | 2000-04-13 | Immunex Corporation | Novel receptor that causes cell death |
| US6297022B1 (en) | 1997-10-08 | 2001-10-02 | Smithkline Beecham Corporation | Method of identifying agonists and antagonists for tumor necrosis related receptor TR1 |
| EP1054961A2 (en) * | 1998-02-17 | 2000-11-29 | Incyte Pharmaceuticals, Inc. | Human short-chain tnf-receptor family protein |
| US20030078211A1 (en) * | 1998-06-24 | 2003-04-24 | Merck & Co., Inc. | Compositions and methods for inhibiting bone resorption |
| WO2000050620A2 (en) | 1999-02-26 | 2000-08-31 | Human Genome Sciences, Inc. | Human endokine alpha and methods of use |
| WO2001077137A1 (en) | 2000-04-12 | 2001-10-18 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| EP1178815A4 (en) * | 1999-04-22 | 2003-02-05 | Human Genome Sciences Inc | THE "DEATH DOMAIN" RECEPTORS |
| US6482411B1 (en) * | 1999-08-27 | 2002-11-19 | Board Of Regents, The University Of Texas System | Methods of reducing bone loss with CD40 ligand |
| US6994976B1 (en) | 1999-11-19 | 2006-02-07 | Tittle Thomas V | Tr3-specific binding agents and methods for their use |
| EP1231937A2 (en) * | 1999-11-19 | 2002-08-21 | Thomas V. Tittle | Tr3-specific binding agents and methods for their use |
| EP2431054A3 (en) | 2000-06-15 | 2013-03-06 | Human Genome Sciences, Inc. | Human tumor necrosis factor delta and epsilon |
| KR20060088905A (ko) | 2000-06-16 | 2006-08-07 | 휴먼 게놈 사이언시즈, 인코포레이티드 | 면역특이적으로 ＢＬｙＳ에 결합하는 항체 |
| CA2426765C (en) | 2000-10-24 | 2012-06-05 | Shunichi Shiozawa | Genomes participating in rheumatoid arthritis, method of the diagnosis thereof, method of evaluating the onset possibility thereof, diagnostic kit for detecting them and therapeutic method and remedies for rheumatoid arthritis |
| US6965023B2 (en) * | 2000-11-17 | 2005-11-15 | The Burnham Institute | Death domain proteins |
| EP2277889B1 (en) | 2001-12-21 | 2014-07-09 | Human Genome Sciences, Inc. | Fusion proteins of albumin and interferon beta |
| ES2428321T3 (es) * | 2003-08-20 | 2013-11-07 | University Of Miami | Composiciones y métodos para tratar la enfermedad del pulmón inflamado |
| ES2611307T3 (es) | 2005-08-30 | 2017-05-08 | University Of Miami | Inmunomodulación de agonistas, antagonistas e inmunotoxinas del receptor del factor de necrosis tumoral 25 (TNFR25) |
| AU2006344395B2 (en) | 2005-10-13 | 2013-05-02 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive diseases |
| US9896511B2 (en) | 2007-01-10 | 2018-02-20 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Antibodies that bind to TL1A and methods of treating inflammatory or autoimmune disease comprising administering such antibodies |
| JP5684130B2 (ja) | 2008-09-26 | 2015-03-11 | トカジェン インコーポレーテッド | 組換えベクター |
| CN102770455B (zh) | 2009-08-03 | 2017-02-08 | 迈阿密大学 | 用于体内扩增调节性t细胞的方法 |
| KR101919170B1 (ko) | 2010-11-19 | 2018-11-15 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 중화 항-ccl20 항체 |
| US9737612B2 (en) | 2011-03-01 | 2017-08-22 | Novo Nordisk A/S | Antagonistic DR3 ligands |
| CA2836898A1 (en) | 2011-05-20 | 2012-11-29 | Government Of The United States, As Represented By The Secretary, Department Of Health And Human Services | Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology and antibodies thereof |
| EP3623478A1 (en) | 2012-10-25 | 2020-03-18 | Tocagen Inc. | Retroviral vector with mini-promoter cassette |
| WO2014110258A1 (en) | 2013-01-09 | 2014-07-17 | Podack Eckhard R | Compositions and methods for the regulation of t regulatory cells using tl1a-ig fusion protein |
| US20160067337A1 (en) | 2013-03-14 | 2016-03-10 | Bristol-Myers Squibb Company | Combination of dr5 agonist and anti-pd-1 antagonist and methods of use |
| JPWO2025018311A1 (enExample) | 2023-07-14 | 2025-01-23 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| EP0103960B1 (en) * | 1982-07-30 | 1991-01-23 | Mach, Bernard François, Prof. | Dna sequences coding for the dr beta-chain locus of the human lymphocyte antigen complex and polypeptides, diagnostic typing processes and products related thereto |
| US5120525A (en) | 1988-03-29 | 1992-06-09 | Immunomedics, Inc. | Radiolabeled antibody cytotoxic therapy of cancer |
| US5349052A (en) | 1988-10-20 | 1994-09-20 | Royal Free Hospital School Of Medicine | Process for fractionating polyethylene glycol (PEG)-protein adducts and an adduct for PEG and granulocyte-macrophage colony stimulating factor |
| CA2006596C (en) | 1988-12-22 | 2000-09-05 | Rika Ishikawa | Chemically-modified g-csf |
| IL106271A (en) * | 1992-09-03 | 2008-03-20 | Yeda Res & Dev | Ligand to TNF 75P receptor and its preparation |
| US5395760A (en) * | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| US5464938A (en) * | 1990-04-09 | 1995-11-07 | Immunex Corporation | Isolated viral protein TNF antagonists |
| US5656272A (en) | 1991-03-18 | 1997-08-12 | New York University Medical Center | Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies |
| DE69229454T2 (de) | 1991-03-28 | 2000-01-05 | Merck & Co., Inc. | Untereinheit-C des vaskulären endothelialen Zellwachstumsfaktors |
| IL99120A0 (en) | 1991-08-07 | 1992-07-15 | Yeda Res & Dev | Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them |
| WO1994009137A1 (en) * | 1992-10-15 | 1994-04-28 | Genentech, Inc. | Antibodies against type 2 tumor necrosis factor receptor |
| JPH08507201A (ja) * | 1992-12-04 | 1996-08-06 | バイオジェン，インコーポレイテッド | リンホトキシン‐β、リンホトキシン‐β複合体、それらの薬学的な調製物および治療への使用 |
| GB9317618D0 (en) | 1993-08-24 | 1993-10-06 | Royal Free Hosp School Med | Polymer modifications |
| CA2174132A1 (en) | 1993-10-14 | 1995-04-20 | Immunex Corporation | Fas antagonists and uses thereof |
| US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| US6608182B1 (en) | 1994-03-08 | 2003-08-19 | Human Genome Sciences, Inc. | Human vascular endothelial growth factor 2 |
| US6599719B2 (en) | 1994-11-07 | 2003-07-29 | Human Genome Sciences, Inc. | Nucleic acid molecules encoding tumor necrosis factor-gamma-alpha |
| ES2285701T3 (es) | 1994-11-07 | 2007-11-16 | Human Genome Sciences, Inc. | Factor-gamma de necrosis tumoral. |
| US5928939A (en) | 1995-03-01 | 1999-07-27 | Ludwig Institute For Cancer Research | Vascular endothelial growth factor-b and dna coding therefor |
| WO1996034095A1 (en) | 1995-04-27 | 1996-10-31 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptors |
| WO1997033904A1 (en) | 1996-03-12 | 1997-09-18 | Human Genome Sciences, Inc. | Death domain containing receptors |
| WO1997033899A1 (en) | 1996-03-14 | 1997-09-18 | Human Genome Sciences, Inc. | Apoptosis inducing molecule i |
| EP0904278A4 (en) | 1996-03-22 | 1999-09-15 | Human Genome Sciences Inc | MOLECULE II INDUCER OF APOPTOSIS |
| JP2000507829A (ja) * | 1996-04-01 | 2000-06-27 | ジェネンテック インコーポレーテッド | Ａｐｏ―２ｌｉおよびａｐｏ―３アポトーシスポリペプチド |
| DE69733204T3 (de) | 1996-07-15 | 2012-03-08 | Chugai Seiyaku K.K. | Neuartige vegf-ähnliche faktoren |
| CA2260754C (en) | 1996-07-15 | 2012-01-24 | Chugai Research Institute For Molecular Medicine, Inc. | Novel vegf-like factor |
| ES2316153T3 (es) | 1996-08-16 | 2009-04-01 | Human Genome Sciences, Inc. | Endoquina alfa humana. |
| AU4055697A (en) | 1996-08-16 | 1998-03-06 | Schering Corporation | Mammalian cell surface antigens; related reagents |
| CA2263890C (en) | 1996-08-23 | 2013-05-14 | Ludwig Institute For Cancer Research | Recombinant vascular endothelial cell growth factor d (vegf-d) |
| AU718474B2 (en) * | 1996-10-04 | 2000-04-13 | Immunex Corporation | Novel receptor that causes cell death |
| CA2266439C (en) | 1996-10-25 | 2009-06-16 | Human Genome Sciences, Inc. | Neutrokine .alpha. |
| WO1998030693A2 (en) | 1997-01-14 | 1998-07-16 | Human Genome Sciences, Inc. | Tumor necrosis factor receptor 5 |
| KR20000070174A (ko) | 1997-01-14 | 2000-11-25 | 벤슨 로버트 에이치. | 종양 괴사 인자 수용체 6α 및 6β |
| JP4450870B2 (ja) | 1997-01-28 | 2010-04-14 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | 死ドメイン含有レセプター４（ｄｒ４：死レセプター４）、ｔｎｆ−レセプタースーパーファミリーのメンバーおよびｔｒａｉｌへの結合 |
| DE69800640T2 (de) | 1997-01-29 | 2001-07-05 | Polymasc Pharmaceuticals Plc, London | Pegylationsverfahren |
| KR100527638B1 (ko) | 1997-03-17 | 2005-11-23 | 휴먼 게놈 사이언시즈, 인코포레이티드 | 사망 도메인을 보유하는 수용체 5 |
| EP0980432A1 (en) | 1997-05-01 | 2000-02-23 | Amgen, Inc. | Chimeric opg polypeptides |
| JP2002503963A (ja) | 1997-06-11 | 2002-02-05 | ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド | ヒト腫瘍壊死因子受容体ｔｒ９ |
-
1996
- 1996-10-17 WO PCT/US1996/016849 patent/WO1997033904A1/en not_active Ceased
-
1997
- 1997-03-11 US US08/815,469 patent/US6153402A/en not_active Expired - Fee Related
- 1997-03-12 JP JP9057503A patent/JPH11170A/ja active Pending
-
1999
- 1999-05-19 US US09/314,889 patent/US6951735B2/en not_active Expired - Lifetime
- 1999-06-16 US US09/333,966 patent/US6759513B2/en not_active Expired - Lifetime
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